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Rubenstein, US

Adam Rubenstein, Coconut Creek, FL US

Patent application numberDescriptionPublished
20120016655DYNAMIC LANGUAGE TRANSLATION OF WEB SITE CONTENT - Methods, systems, and computer readable medium for providing translated web content. A request is received from a user for content in a second language translated from content in a first language from a first Internet source. The content in the first language is obtained and divided into one or more translatable components. Whether the one or more translatable components have been previously translated, via at least one of machine translation, human translation, and a combination thereof, into the second language and stored as translated components in a storage is determined. If there are one or more translatable components previously translated and stored, the content is generated in the second language by modifying the content in the first language so that at least some translatable components are replaced with corresponding translated components and sent in the second language to the user as a response to the request.01-19-2012
20120016929DYNAMIC LANGUAGE TRANSLATION OF WEB SITE CONTENT - Methods, systems, and computer readable medium for providing content with respect to a website. A request for content is received where the request includes information related to a user. One or more pieces of localized content associated with at least one condition is retrieved when it is determined that the at least one condition is consistent with the information related to the user, where each localized content is localized with respect to the content requested. At least one of the retrieved localized content is identified when the information related to the user meets the associated at least one condition. The identified at least one localized content is sent as a response to the received request for content.01-19-2012
20120017146DYNAMIC LANGUAGE TRANSLATION OF WEB SITE CONTENT - Methods, systems, and computer readable medium for facilitating selection of a preferred language associated with a website. In one example, information including information relating to a user is first received via the communication platform. The received information is then automatically analyzed to estimate a preferred language in which the user likely uses to view content from the website. A selector is displayed with an available selection of a language that most closely matches the estimated preferred language to allow the user to specify the user's preferred language with respect to the website. The user's preferred language is stored, and the user is redirected to the website in the user's preferred language.01-19-2012

Adam Rubenstein, Boca Raton, FL US

Patent application numberDescriptionPublished
20090281790DYNAMIC LANGUAGE TRANSLATION OF WEB SITE CONTENT - A method, system and computer program product for providing translated web content is disclosed. The method includes receiving a request from a user on a web site, the web site having a first web content in a first language, wherein the request calls for a second web content in a second language. The method further includes dividing the first web content into a plurality of translatable components and generating a unique identifier for each translatable component. The method further includes identifying a plurality of translated components of the second web content using the unique identifier of each of the plurality of translatable components of the first web content and putting the plurality of translated components of the second web content to preserve a format that corresponds to the first web content. The method further includes providing the second web content in response to the request that was received.11-12-2009
20100030550SYNCHRONIZATION OF WEB SITE CONTENT BETWEEN LANGUAGES - A system, method and computer readable medium for synchronizing web content is disclosed. The method includes retrieving a first web content in a first language from a web site, the first web content corresponding to a second web content wherein the second web content is a translation in a second language of the first web content. The method further includes dividing the first web content into a plurality of translatable components and generating a unique identifier for each of the plurality of translatable components. The method further includes matching each of the plurality of translatable components to a plurality of translated components of the second web content using the unique identifier of each of the plurality of translatable components. If a translatable component is not matched to a translated component, the method further includes designating the translatable component for translation into the second language.02-04-2010
20100169764AUTOMATION TOOL FOR WEB SITE CONTENT LANGUAGE TRANSLATION - A system, method and computer readable medium for providing translated web content is disclosed. The method on an information processing system includes retrieving a first content in a first language and parsing the first content into a plurality of translatable components. The method further includes generating a unique identifier for each of the plurality of translatable components of the first content and queuing the plurality of translatable components and corresponding unique identifiers for translation into a second language. The method further includes, for each of the plurality of translatable components, storing a translated component and an associated unique identifier corresponding to the translatable component, thereby storing a plurality of translated components and corresponding unique identifiers.07-01-2010
20100174525ANALYZING WEB SITE FOR TRANSLATION - A system, method and computer readable medium for synchronizing web content is disclosed. The method includes retrieving a first web content in a first language from a web site, the first web content corresponding to a second web content wherein the second web content is a translation in a second language of the first web content. The method further includes dividing the first web content into a plurality of translatable components and generating a unique identifier for each of the plurality of translatable components. The method further includes matching each of the plurality of translatable components to a plurality of translated components of the second web content using the unique identifier of each of the plurality of translatable components. If a translatable component is not matched to a translated component, the method further includes designating the translatable component for translation into the second language.07-08-2010
20110209038DYNAMIC LANGUAGE TRANSLATION OF WEB SITE CONTENT - A method, system and computer program product for providing translated web content is disclosed. The method includes receiving a request from a user on a web site, the web site having a first web content in a first language, wherein the request calls for a second web content in a second language. The method further includes dividing the first web content into a plurality of translatable components and generating a unique identifier for each translatable component. The method further includes identifying a plurality of translated components of the second web content using the unique identifier of each of the plurality of translatable components of the first web content and putting the plurality of translated components of the second web content to preserve a format that corresponds to the first web content. The method further includes providing the second web content in response to the request that was received.08-25-2011

Patent applications by Adam Rubenstein, Boca Raton, FL US

Allan Rubenstein, New York, NY US

Patent application numberDescriptionPublished
20110190237Macrocyclic Prodrug Compounds Useful as Therapeutics - The present invention includes macrocyclic prodrug compounds, pharmaceutical compositions containing them. The present invention also includes use of these compounds in the treatment of various diseases including an autoimmune disease, an inflammatory disease, a neurological or neurodegenerative disease, cancer, a cardiovascular disease, allergy, asthma, a hormone-related disease, and tumors or symptoms resulting from neurofibromatosis.08-04-2011

Allan E. Rubenstein, New York, NY US

Patent application numberDescriptionPublished
20090118240LOCAL TREATMENT OF NEUROFIBROMAS - A method for treating a neurofibroma, e.g. dermal neurofibroma, a subdermal neurofibroma, or a superficial plexiform neurofibroma, in a subject in need of such treatment is disclosed. The method comprises locally applying a composition to a neurofibroma either topically or intralesionally. This method does not encompass systemic administration of the composition to the subject to have an effect on the neurofibromas. Compositions useful for such treatments and methods of preparing the compositions are disclosed.05-07-2009
20100292218Treatment Of Neurofibromatosis With Radicicol And Its Derivatives - The present invention provides compounds of formulae Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va and the therapeutic use thereof. The present invention also includes methods of treating NF2-deficient or NF1-deficient cells or neurodegenerative diseases with radicicol or its derivatives, such as one or more compounds of formula I, II, III, IV, V, Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va. Furthermore, the present invention is directed to methods of inhibiting the growth of NF2-deficient or NF1-deficient tumors. The methods comprise contacting NF2-deficient or NF1-deficient tumor cells with radicicol or its derivatives, such as one or more compounds of formula I, II, III, IV, V, Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va. The present invention is also directed to the combinational use of radicicol or its derivatives, such as one or more compounds of formula I, II, III, IV, V, Ia, Ia′, IIa, IIa′, IIIa, IIIa′, IVa, or Va with at least one additional active agent, such as one or more HSP90 inhibitors.11-18-2010
20120315298LOCAL TREATMENT OF NEUROFIBROMAS - A method for treating a neurofibroma, e.g. dermal neurofibroma, a subdermal neurofibroma, or a superficial plexiform neurofibroma, in a subject in need of such treatment is disclosed. The method comprises locally applying a composition to a neurofibroma either topically or intralesionally. This method does not encompass systemic administration of the composition to the subject to have an effect on the neurofibromas. Compositions useful for such treatments and methods of preparing the compositions are disclosed.12-13-2012

Patent applications by Allan E. Rubenstein, New York, NY US

Brandon Rubenstein, Loveland, CO US

Patent application numberDescriptionPublished
20090101317JACKET FOR HEAT DISPERSION DEVICE - An apparatus comprising a heat dispersion device having a first end. The first end has a shape different than that of the remainder of the heat dispersion device. The apparatus also comprises a jacket coupled to the heat dispersion device at the first end. The jacket has another shape associated with that of the remainder of the heat dispersion device.04-23-2009
20090111293RETRACTABLE PROTECTION APPARATUS FOR ELECTRONIC DEVICE PINS - An apparatus for protecting an array of pins of an electronic device is provided. The apparatus includes a pin protector defining an array of holes therethrough, wherein each hole is configured to receive one of the pins. The apparatus also comprises a spring element configured to bias the pin protector away from the electronic device toward an end of each of the pins. The spring element is also configured to allow the pin protector to be retracted toward the electronic device to expose the pins for insertion into a socket or similar component.04-30-2009
20110085296Cooling System For A Computer Blade - A cooling system for a computer blade is disclosed. The cooling system comprises a main printed circuit (PC) board with at least one component mounted on a top side of the main PC board. A heat transfer plate is located at the first end of the main PC board. An airflow divider is mounted on, and is perpendicular with, the top side of the main PC board. The airflow divider runs in an axis generally parallel with the first side of the main PC board. A lid is coupled to the main PC board thereby enclosing the main PC board, the heat transfer plate and the airflow divider. The lid encloses a first airflow channel running along the first side of the main PC board and a second airflow channel running along the second side of the main PC board. A fan is located on top side of the main PC board in the first airflow channel. The fan is configured to re-circulate air from the second airflow channel through the first airflow channel, past the heat transfer plate, and then back into the second airflow channel.04-14-2011
20110304979COOLING APPARATUS - A cooling apparatus is disclosed. The cooling apparatus comprising a printed circuit (PC) board with an integrated circuit (IC) socket mounted onto the top side of the PC board. A mounting frame generally in the shape of a plate, with a first opening passing through the center of the plate, is mounted on the top side of the PC board with the IC socket located inside the first opening. A cold plate is attached to the mounting frame, the cold plate has an opening that passes through the cold plate. The opening in the cold plate is sized to allow an IC to be inserted into the IC socket through the opening. A fluid passageway is formed inside the cold plate. A fluid inlet port and a fluid outlet port are mounted on the cold plate and coupled to a first end and a second end of the fluid passageway, respectively. A heat spreader is removably attached to the top side of the cold plate wherein the bottom side of the heat spreader is configured to contact the top side of an IC when the IC is mounted in the IC socket.12-15-2011
20120012714DUAL-ARM CABLE-MANAGEMENT SYSTEM - One embodiment of the present invention employs two articulated cable-management arms, each articulated cable-management arm pivotally mounted, at a first end, to a system frame or rack and pivotally mounted, at a second end, to a component-system enclosure or sliding component-system-enclosure mount. The articulated cable-management arms provide mechanical channels through which cables connected to the back of a component-system enclosure are routed together to a structural member of the rack or frame.01-19-2012
20120020022PRINTED CIRCUIT BOARD COOLING ASSEMBLY - A cooling apparatus for a printed circuit board assembly is disclosed. The cooling apparatus comprises a main printed circuit (PC) board 01-26-2012
20120039036THERMAL BUS BAR FOR A BLADE ENCLOSURE - A cooling system for a blade enclosure is disclosed. The cooling system comprises a thermal bus bar (TBB) 02-16-2012
20120125573HEAT STORAGE BY PHASE-CHANGE MATERIAL - Methods and means related to rejecting heat through thermal storage are provided. A heat sink includes internal cavities containing a phase-change material. Heat from a thermal load is rejected by flowing fluid coolant at a normal operating temperature. Failure of the fluid coolant system causes heat storage within the phase-change material at a temperature slightly greater than the normal operating temperature. Restoration of the fluid coolant system results in stored heat rejection and a return to a normal operating temperature. Normal operation of the thermal load can be performed while efforts are made to restore the fluid coolant system.05-24-2012
20120134678SYSTEM FOR PROVIDING PHYSICALLY SEPARATED COMPUTE AND I/O RESOURCES IN THE DATACENTER TO ENABLE SPACE AND POWER SAVINGS - An embodiment of a system and method disaggregate I/O resources from a server's compute resources, such as CPU and memory, by moving the server's local I/O devices to a remote location apart from the server's compute resources. An embodiment uses optical technology to accomplish the fast communication speeds needed between the compute resources and the remotely located I/O resources. Specifically, an embodiment uses fiber-optic cables and electrical-to-optical conversion to facilitate communication between the compute resources and the I/O resources. The compute resources and the remotely located I/O resources can be designed differently to allow conductive liquid cooling for the compute resources and air cooling for the I/O resources.05-31-2012
20120325013FLOW MEASUREMENT SYSTEM AND METHODS - Flow measurement systems and methods are provided. A flow measurement system can include at least one heat-producing computing device (12-27-2012

Patent applications by Brandon Rubenstein, Loveland, CO US

Brandon A. Rubenstein, Lynnwood, WA US

Patent application numberDescriptionPublished
20130018523Indirect Thermal Fan ControlAANM Rubenstein; Brandon A.AACI LynnwoodAAST WAAACO USAAGP Rubenstein; Brandon A. Lynnwood WA US - Indirect thermal fan control is described. In one or more implementations, a speed of a fan may be adjusted based on indirect measurements of temperature. For example, a temperature of air entering an enclosure and a current draw of an electrical component within the enclosure may be determined. A speed of a fan may then be adjusted based on the temperature of the air and the current draw of the component to change a flow of the air over the electrical component.01-17-2013

Daniel Rubenstein, New York, NY US

Patent application numberDescriptionPublished
20090222477METHODS, SYSTEMS, AND MEDIA FOR FORMING LINEAR COMBINATIONS OF DATA - Methods, systems, and media for forming linear combinations of data are provided. In some embodiments, methods for forming a linear combination of data include: receiving at a device a first codeword, wherein the first codeword comprises a linear combination of at least a first data unit including data, and a second data unit including data; encoding at the device the first codeword and a third data unit including data to form a second codeword, wherein the second codeword includes a linear combination of at least the first data unit, the second data unit, and the third data unit; and transmitting from the device the second codeword.09-03-2009

Daniel S. Rubenstein, New York, NY US

Patent application numberDescriptionPublished
20090080377Distributed Channel Management Based on Channel Hopping in Uncoordinated 802.11 Based WLAN - In accordance with the invention, a method includes i) obtaining first for each AP hopping sequences of other interfering APs; and ii) determining for the AP a respective hopping sequence that maximizes each APs throughput. Preferably, the step of determining comprises for each slot AP choosing a channel that minimizes the number of edges which violate a k-coloring property. In an exemplary embodiment, the method further includes the step of the AP selecting one of (a) a channel uniformly at random from all such channels and (b) selecting a channel that distributes interference evenly as possible among neighboring APs.03-26-2009

David Rubenstein, Falmouth, ME US

Patent application numberDescriptionPublished
20100220008SYSTEM AND METHOD FOR OPTIMAL TIME, POSITION AND HEADING SOLUTION THROUGH THE INTEGRATION OF INDEPENDENT POSITIONING SYSTEMS - A system for, and method of, blending (or integrating) pseudo-range or position measurements and bearing-to-transmitter measurements from an eLORAN or LORAN-C receiver and position (alternatively, pseudo ranges) and velocity (alternatively pseudo-range rate) measurements from a GPS receiver. The described system can also be integrated with additional external positioning systems. In the context of an inertial navigation system (INS) application, this combined GPS/LORAN signal can be employed to provide external positioning solutions, potentially integrated with measurements from devises such as accelerometers, gyroscopes, altimeters, etc. The system includes a GPS signal input, a LORAN signal input, preprocessors for each, and an integrator to combine the two preprocessed signals to estimate errors in the full trajectory variables.09-02-2010

David Rubenstein, Westminster, CA US

Patent application numberDescriptionPublished
20080243034Body decompression technique for pain treatment - A method for treatment of compressed fascial tissues on the human body comprising a two part process. The first part comprises a treatment of fascial tissues around the cranium and the second part comprises a treatment of fascial tissues along the torso and limbs. The first part administers a method of palpation to tactilely identify areas of compressed fascial tissue and treats identified areas using compressive and tractional forces applied to the area perpendicularly to one another until compression is released. The second part includes a sequences of stretching postures that elongate the tissues in the torso and limbs further relieving the body of compressed tissues. The second part is aided by use of an orientation device that provides reference points for commencement of a stretching posture and for directing movement thereafter. A platform device is also included for promoting a stretching posture and a balancing aid is provided for supporting the weight of the torso during select exercises.10-02-2008

David Rubenstein, Naperville, IL US

Patent application numberDescriptionPublished
20090117910Methods and Apparatus to Perform Wireless Peering in Communication Systems - Methods and apparatus to route communications at an interexchange carrier are disclosed. One method of routing communications may include receiving a communication at the interexchange carrier, determining a destination at which the communication is to terminate, and routing the communication from the interexchange carrier through a terminating access charge free line to a terminating mobile telephone switching office.05-07-2009

David J. Rubenstein, Woodland Hills, CA US

Patent application numberDescriptionPublished
20100137721TRANSURETHRAL ULTRASONIC IMAGING SYSTEM - An ultrasound scanning system and methods of using the same. In one preferred form, an ultrasound scanning system comprises an acoustic imaging catheter comprising an ultrasonic transducer, a motion control system and an imaging computer system for imaging a patient's genitourinary system. In another preferred form, an ultrasound scanning system is used for imaging a patient's prostate gland.06-03-2010

Patent applications by David J. Rubenstein, Woodland Hills, CA US

David Scott Rubenstein, Chapel Hill, NC US

Patent application numberDescriptionPublished
20080207519Inhibition of Hsp27 Phosphorylation for the Treatment of Blistering Disorders - A method of treating a blistering disorder, which includes administering to a target tissue in a subject in need thereof an effective amount of a composition that inhibits activation of the HSP27 phosphorylation pathway.08-28-2008

Edward Rubenstein, Hillsborough, CA US

Patent application numberDescriptionPublished
20110088457COMPOSITIONS, SYSTEMS AND METHODS FOR THE DIAGNOSIS, PREVENTION AND TREATMENT OF DISORDERS ASSOCIATED WITH AZETIDINE-2-CARBOXYLIC ACID - Methods and systems for detecting azetidine-2-carboxylic acid (Aze) in food consumable by humans and animals are provided. Also provided are methods and systems for inactivating Aze in food and byproducts, as well as other methods for the diagnosis, prevention, and treatment of disorders associated with Aze.04-21-2011

Edward B. Rubenstein, Houston, TX US

Patent application numberDescriptionPublished
20120238590COMPOSITIONS FOR TREATING CANCER-RELATED FATIGUE AND METHODS OF SCREENING THEREOF - An animal model has been developed based the understanding that a central mechanism in patients with CTRF is that chemotherapy and/or radiation initiates canonical pathways leading to the development of disrupted sleep architecture, resulting in disruption of REM sleep and fatigue and cognitive dysfunction. Drugs that restore the activity patterns and levels towards normal and/or decrease the pro-inflammatory cytokines associated with the disrupted sleep, should be effective in alleviating one or more symptoms of CTRF. Pentoxifylline was demonstrated to improve activity levels in animals treated with etoposide.09-20-2012

Eric Rubenstein, Longmeadow, MA US

Patent application numberDescriptionPublished
20100116136Carbon-based sorbent for gas storage, and method for preparation thereof - The method enables control over carbon pore structure to provide sorbents that are particularly advantageous for the adsorption of specific gases. It involves preparation of a sorbent precursor material, carbonization of the precursor material, and, usually, activation of the carbonized material. The resultant material is subjected to heat treatment and/or to surface conditioning by a reducing gas at elevated temperatures.05-13-2010

Eric P. Rubenstein, East Hartford, CT US

Patent application numberDescriptionPublished
20090114830Apparatus and Method for Detection of Radiation - Digital images or the charge from pixels in light sensitive semiconductor based imagers may be used to detect gamma rays and energetic particles emitted by radioactive materials. Methods may be used to identify pixel-scale artifacts introduced into digital images and video images by high energy gamma rays. Statistical tests and other comparisons on the artifacts in the images or pixels may be used to prevent false-positive detection of gamma rays. The sensitivity of the system may be used to detect radiological material at distances in excess of 50 meters. Advanced processing techniques allow for gradient searches to more accurately determine the source's location, while other acts may be used to identify the specific isotope. Coordination of different imagers and network alerts permit the system to separate non-radioactive objects from radioactive objects.05-07-2009
20110176707IMAGE ANALYSIS BY OBJECT ADDITION AND RECOVERY - The invention described herein is generally directed to methods for analyzing an image. In particular, crowded field images may be analyzed for unidentified, unobserved objects based on an iterative analysis of modified images including artificial objects or removed real objects. The results can provide an estimate of the completeness of analysis of the image, an estimate of the number of objects that are unobserved in the image, and an assessment of the quality of other similar images.07-21-2011
20110307222APPARATUS AND METHOD FOR DETECTION OF RADIATION - Digital images or the charge from pixels in light sensitive semiconductor based imagers may be used to detect gamma rays and energetic particles emitted by radioactive materials. Methods may be used to identify pixel-scale artifacts introduced into digital images and video images by high energy gamma rays. Statistical tests and other comparisons on the artifacts in the images or pixels may be used to prevent false-positive detection of gamma rays. The sensitivity of the system may be used to detect radiological material at distances in excess of 50 meters. Advanced processing techniques allow for gradient searches to more accurately determine the source's location, while other acts may be used to identify the specific isotope. Coordination of different imagers and network alerts permit the system to separate non-radioactive objects from radioactive objects.12-15-2011
20120077544APPARATUS AND METHOD FOR DETECTION OF RADIATION - Digital images or the charge from pixels in light sensitive semiconductor based imagers may be used to detect gamma rays and energetic particles emitted by radioactive materials. Methods may be used to identify pixel-scale artifacts introduced into digital images and video images by high energy gamma rays. Statistical tests and other comparisons on the artifacts in the images or pixels may be used to prevent false-positive detection of gamma rays. The sensitivity of the system may be used to detect radiological material at distances in excess of 50 meters. Advanced processing techniques allow for gradient searches to more accurately determine the source's location, while other acts may be used to identify the specific isotope. Coordination of different imagers and network alerts permit the system to separate non-radioactive objects from radioactive objects.03-29-2012
20120177251IMAGE ANALYSIS BY OBJECT ADDITION AND RECOVERY - The invention described herein is generally directed to methods for analyzing an image. In particular, crowded field images may be analyzed for unidentified, unobserved objects based on an iterative analysis of modified images including artificial objects or removed real objects. The results can provide an estimate of the completeness of analysis of the image, an estimate of the number of objects that are unobserved in the image, and an assessment of the quality of other similar images.07-12-2012

Patent applications by Eric P. Rubenstein, East Hartford, CT US

Eric P. Rubenstein, Longmeadow, MA US

Patent application numberDescriptionPublished
20110167530High-strength porous carbon and its multifunctional applications - High-strength porous carbon and a method of its manufacture are described for multifunctional applications, such as ballistic protection, structural components, ultracapacitor electrodes, gas storage, and radiation shielding. The carbon is produced from a polymer precursor via carbonization, and optionally by surface activation and post-treatment.07-14-2011

Jason Rubenstein, Brookfield, WI US

Patent application numberDescriptionPublished
20100137700CATHETERS AND ELECTROPHYSIOLOGICAL DEVICES - The present invention provides systems and methods of use for catheters and electrophysiological devices. In particular, the present invention provides coronary catheters within which an extendable electrode array is housed.06-03-2010
20110306904ABLATION DEVICES AND RELATED METHODS THEREOF - The present invention relates generally to devices for performing targeted tissue ablation in a subject. In particular, the present invention provides devices configured to deliver energy to a targeted tissue region without causing damage to untargeted tissue.12-15-2011

Jason Rubenstein, Naperville, IL US

Patent application numberDescriptionPublished
20100125189SYSTEMS AND METHODS FOR CATHETER STABILITY - The present invention provides systems and methods for stabilizing catheters, such as decapolar coronary sinus catheters in veins. In particular, the present invention provides fixation elements for improved tissue contact and stability.05-20-2010
20100125281CARDIAC PACING LEAD AND DELIVERY SHEATH - The present invention provides compositions and methods related to epicardial pacing systems. In particular, the present invention provides a novel delivery sheath and cardiac pacing lead to be deployed in the pericardial space via a percutaneous approach.05-20-2010

Jeff David Rubenstein, Sugar Land, TX US

Patent application numberDescriptionPublished
20120204142OILFIELD APPLICATION SYSTEM - A computerized system for oil field applications. The computerized system may include an oilfield application and an oilfield application development kit that provides a software architecture for developing one or more plug-in components that may be executable by the oilfield application. The computerized system may also include an online distribution center that facilitates access to the plug-in components.08-09-2012

John L. Rubenstein, San Francisco, CA US

Patent application numberDescriptionPublished
20090311222TRANSPLANTATION OF NEURAL CELLS - Restoration or increase of inhibitory interneuron function in vivo is achieved by transplantation of MGE cells into the brain. Compositions containing MGE cells are provided as are uses to treat various diseases characterised by abnormal inhibitory interneuron function or in cases where increase inhibition may ameliorate neural circuits that are abnormally activated.12-17-2009

John L.r. Rubenstein, San Francisco, CA US

Patent application numberDescriptionPublished
20110165129Ameliorating Nervous Systems Disorders - The present disclosure provides methods for the treatment of a mammal having a neurological condition, disease, or injury. The methods involve increasing the number of functional GABAergic interneurons at or near the site of the neurological disease, injury, or condition.07-07-2011

Michael Rubenstein, Cammbridge, MA US

Patent application numberDescriptionPublished
20110211771Content Aware Resizing of Images and Videos - A method resizes input images by first constructing a grid graph. The grid graph includes one node for each pixel in the input image, and adjacent nodes in the grid graph are connected by arcs. Each arc is directed and has an associated cost. A cut is applied to the arcs of the grid graph using a cost function. A seam of pixels is determined from the cut so that coordinates of the pixels in the seam enforce monotonicity and connectivity constraints. Then, the input image is resized according to the seam to produce an output image while minimizing a change of energy in the output image when compared with the input image.09-01-2011

Paul E. Rubenstein, Roswell, GA US

Patent application numberDescriptionPublished
20100148920AUTOMATED PRESENCE DETECTOR FOR MOTOR VEHICLES - The disclosure presents various embodiments, as well as features and aspects thereof, of a presence detection technique and system used in motor vehicles. Exemplary embodiments recognize the presence of a motor vehicle driver in, or near, a motor vehicle. Based on the recognized presence of a driver, embodiments of an automated presence detector for motor vehicles may inhibit, block or otherwise restrict access to services or applications associated with the driver's mobile device. To recognize the presence of a motor vehicle driver, embodiments may employ wireless radio frequency standards, such as Bluetooth, position indication technologies, such as GPS, or any other means suitable for correlating the physical presence of a driver with a motor vehicle.06-17-2010
20100153983AUTOMATED PRESENCE FOR SET TOP BOXES - Exemplary automated presence detection systems comprise set top box components equipped with a Bluetooth receiver, or another receiver configured to receive data from a personal identification device via a wireless and automatic radio frequency standard. In various embodiments, the Bluetooth receiver may be integrated into the set top box or may operate as an adjunct to an existing set top box. The wireless radio frequency receiver in the set top box will poll to determine the presence of previously paired personal identification devices. If any such device is present, then the set top box will track and record the presence of a viewer that is associated with the device and correlate the viewer's presence with content displayed on the television or other local content display component. Alternatively, based on detected viewer presence, some embodiments of an automated presence detection system may be configured to push and/or restrict specific content. Further, some embodiments are configured to gather statistical data concerning viewer behavior and/or exposure to displayed content.06-17-2010

Richard Rubenstein, Staten Island, NY US

Patent application numberDescriptionPublished
20100261195RAPID ANTEMORTEM DETECTION OF INFECTIOUS AGENTS - Methods for detection of the presence or absence of PrP10-14-2010
20110042585FIBER OPTICAL ASSEMBLY FOR FLUORESCENCE SPECTROMETRY - System and method for analyzing a sample for the presence of an analyte in a sample, the system comprising a sample holder for containing the sample; an excitation source in optical communication with the sample, wherein radiation from the excitation source is directed to the sample, and wherein the radiation induces a fluorescence signal; and at least one linear array comprising a proximal end disposed in proximity to the sample holder and an end port distal from the proximal end; a plurality of optical fibers extending from the proximal end to the end port and having a first end and a second end, wherein the first ends of the individual optical fibers are substantially coplanar and adjacent to one another, and wherein the second ends of the optical fibers form a non-linearly arranged bundle, and wherein the plurality of optical fibers transmits the fluorescent signal from the proximal end to the end port; and an end port assembly optically coupled to the end port, the end port assembly comprising a single photo-detector, wherein the photo-detector detects the fluorescent signal and converts the fluorescent signal into an electrical signal.02-24-2011
20120112069FIBER OPTICAL ASSSEMBLY FOR FLUORESCENCE SPECTROMETRY - System is provided for detecting the presence of an analyte of interest in a sample, said system comprising an elongated, transparent container for a sample; an excitation source in optical communication with the sample, wherein radiation from the excitation source is directed along the length of the sample, and wherein the radiation induces a signal which is emitted from the sample; and, at least two linear arrays disposed about the sample holder, each linear array comprising a plurality of optical fibers having a first end and a second end, wherein the first ends of the fibers are disposed along the length of the container and in proximity thereto; the second ends of the fibers of each array are bundled together to form a single end port.05-10-2012

Patent applications by Richard Rubenstein, Staten Island, NY US

Steven M. Rubenstein, Pacifica, CA US

Patent application numberDescriptionPublished
20090221635QUINOLINYL AND BENZOTHIAZOLYL MODULATORS - Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPARγ. In particular, the compounds of the invention modulate the function of PPARγ. The subject methods are particularly useful in the treatment and/or prevention of diabetes, obesity, hypercholesterolemia, rheumatoid arthritis and atherosclerosis.09-03-2009

Steven M. Rubenstein, Pacific, CA US

Patent application numberDescriptionPublished
20100113522COMPOUNDS FOR THE MODULATION OF PPARgamma ACTIVITY - Modulators of PPARγ activity are provided which are useful in pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes and obesity.05-06-2010