Roymans
Dirk André E. Roymans, Turnhout BE
Patent application number | Description | Published |
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20100035363 | Homogeneous Time Resolved Fluorescence Based Test System for Paramyxoviridae - The present invention concerns a fluorescence resonance energy transfer based high throughput test system to measure the formation of the RSV F1 six-helix bundle. In a first embodiment the current invention relates to a homogeneous time resolved fluorescence-based test system comprising a first helical polypeptide consisting essentially of the sequence of IQN57 (SEQ ID NO: 1); a second helical polypeptide consisting essentially of the sequence of C45 (SEQ ID NO: 2) wherein said IQN57 is labeled with a light emitting fluorophore and said C45 is labeled with an ultra-violet excitable fluorophore. | 02-11-2010 |
Dirk André E. Roymans, Turnhout BE
Patent application number | Description | Published |
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20100035363 | Homogeneous Time Resolved Fluorescence Based Test System for Paramyxoviridae - The present invention concerns a fluorescence resonance energy transfer based high throughput test system to measure the formation of the RSV F1 six-helix bundle. In a first embodiment the current invention relates to a homogeneous time resolved fluorescence-based test system comprising a first helical polypeptide consisting essentially of the sequence of IQN57 (SEQ ID NO: 1); a second helical polypeptide consisting essentially of the sequence of C45 (SEQ ID NO: 2) wherein said IQN57 is labeled with a light emitting fluorophore and said C45 is labeled with an ultra-violet excitable fluorophore. | 02-11-2010 |
Dirk Andre Emmy Roymans, Turnhout BE
Patent application number | Description | Published |
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20150226695 | POTENTIOMETRIC SENSOR - The invention relates to a flux based ion selective electrode sensing device for biological molecules or substances. The device comprises an ion selective sensor, an incorporated passive flux of the ion and biological recognition element. The device measures the change in flux away from the sensor of the ion fluxing out of the sensor upon binding of the analyte on the sensor surface by means of the biological recognition element. | 08-13-2015 |
Dirk André Emmy Roymans, Mechelen BE
Patent application number | Description | Published |
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20110009408 | METHODS FOR IDENTIFIYING INHIBITORS AGAINST VIRUSES THAT USE A CLASS I FUSION PROTEIN - The invention concerns the generation of a three dimensional model of the six helix bundle (6HB) complexed with an inhibitor and the use of that model to identify, screen and/or develop inhibitors against viruses that use a class I fusion protein. Such inhibitors of viruses that use a class I fusion protein may be effective for treating, for example, respiratory infections by Respiratory Syncytial Virus (RSV). | 01-13-2011 |
Dirk André Emmy Roymans, Mechelen BE
Patent application number | Description | Published |
---|---|---|
20110009408 | METHODS FOR IDENTIFIYING INHIBITORS AGAINST VIRUSES THAT USE A CLASS I FUSION PROTEIN - The invention concerns the generation of a three dimensional model of the six helix bundle (6HB) complexed with an inhibitor and the use of that model to identify, screen and/or develop inhibitors against viruses that use a class I fusion protein. Such inhibitors of viruses that use a class I fusion protein may be effective for treating, for example, respiratory infections by Respiratory Syncytial Virus (RSV). | 01-13-2011 |