Roughton
Andrew Roughton, Port Hope CA
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20120295903 | FLAVIN DERIVATIVES - The present invention relates novel flavin derivatives and other flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives. The invention also provides method of making novel flavin derivatives. | 11-22-2012 |
20130029980 | FLAVIN DERIVATIVES - The present invention relates novel flavin derivatives, their use and compositions for use as riboswitch ligands and/or anti-infectives. | 01-31-2013 |
Andrew L. Roughton, Plainsboro, NJ US
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20090281075 | ISOMERIC PURINONES AND 1H-IMIDAZOPYRIDINONES AS PKC-THETA INHIBITORS - A chemical genus of purinones and 1H-imidazopyridinones, which are useful as PKCθ inhibitors, and their methods of use are disclosed. The genus is represented by the formula I: | 11-12-2009 |
Andrew Laird Roughton, Plainsboro, NJ US
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20090264416 | N-BENZYL,N'-ARYLCARBONYLPIPERAZINE DERIVATIVES - The present invention relates to N-benzyl,N′-arylcarbonylpiperazine derivatives having the general formula I | 10-22-2009 |
20110046131 | PURINES AS PKC-THETA INHIBITORS - A chemical genus of purines, which are useful as PKCθ inhibitors, is disclosed. The genus is represented by the formula (I); A representative example is: (II) | 02-24-2011 |
20110218189 | PYRROLO[2,3-d]PYRIMIDIN-2-YL-AMINE DERIVATIVES AS PKC-THETA INHIBITORS - The present invention relates to a pyrrolo[2,3-d]pyrimidin-2-yl-amine derivative according to formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceutical composition comprising one or more of said pyrrolo[2,3-d]pyrimidine-2-ylamine derivatives and to their use in therapy, for instance in the treatment of PKCθ mediated disorders. | 09-08-2011 |
Andrew Laird Roughton, Toronto CA
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20110065764 | 5- PHENYL-ISOXAZOLE-3-CARBOXAMIDE DERIVATIVES AS TRPV1 MODULATORS - The present invention relates to isoxazole-3-carboxamide derivative having the general Formula (I), or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of said isoxazole-3-carboxamide derivatives for the treatment of TRPV1 mediated disorders, such as acute and chronic pain disorders, acute and chronic neuropathic pain, acute and chronic inflammatory pain, respiratory diseases, and lower urinary tract disorders. | 03-17-2011 |
Andrew Laird Roughton, Port Hope CA
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20120015958 | 1-(4-UREIDOBENZOYL)PIPERAZINE DERIVATIVES - The present invention relates to 1-(4-ureidobenzoyl)piperazine derivatives having the general Formula I (We bring to your attention that formula I is not provided on this electronic version as it is provided in the abstract of the paper copy) Wherein R | 01-19-2012 |
20120071481 | ISOXAZOLE-5-CARBOXAMIDE DERIVATIVES - The present invention relates to isoxazole-3-carboxamide derivative having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of said isoxazole-3-carboxamide derivatives for the treatment of TRPV1 mediated disorders, such as acute and chronic pain disorders, acute and chronic neuropathic pain, acute and chronic inflammatory pain, respiratory diseases, and lower urinary tract disorders. | 03-22-2012 |
Jason Roughton, Saginaw, MI US
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20130283741 | Industrial Air Vacuum Filter Assembly - An air vacuum filter assembly is disclosed for use in filtering particulates from smoke and air during scrap metal cutting processes. The air vacuum filter assembly includes an enclosed container forming an air chamber therethrough between an air inlet and an exhaust outlet. A pair of fans creates a vacuum pressure in the container to suction air through the air chamber. A deflector within the enclosed container deflects and directs the air along a predetermined path through the air chamber between the air inlet and exhaust outlet. A series of filters are provided in the air flow path to filter and clean particulates from the smoke and air prior to the air exiting the container through the exhaust outlet and into the atmosphere. | 10-31-2013 |
Micheal Roughton, Belle Mead, NJ US
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20090084278 | Process for making metalized micro-embossed films - The present invention provides a process for manufacturing a metalized micro-embossed plastic film using a shim made from a flexographic plate. A digital image is transferred to the flexographic plate and the flexographic plate is processed to create a shim having a raised image corresponding to the digital image. A film is embossed by extruding the film across the flexographic plate, creating a micro-embossed surface in the film. The micro-embossed surface of the film can further be metalized to enhance the visual effects of the image when viewed from the non-embossed surface of the film. | 04-02-2009 |