Roos, NL
Andre Leonardus Roos, Delft NL
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20080220124 | Transfer of Active Compounds to Curd During Cheese Making - The present invention relates to a composition comprising a whey protein and an active compound, wherein the composition releases at most 30 wt % of the active compound when hydrated in Jennes-Koops buffer at room temperature during a period of 30 minutes. The invention also relates to a production method for the composition. During the cheese making process this composition can be added to milk. The enzymes are then mainly released from the particle after the separation of curd from the whey has taken place. | 09-11-2008 |
20090042809 | Blood Pressure Lowering Protein Hydrolysates - The present invention describes the tripeptide MAP and/or the tripeptide ITP and/or a salt thereof. | 02-12-2009 |
20100286034 | USES FOR AQUEOUS STREAMS CONTAINING PROTEINS - The present invention relates to a protein hydrolysate comprising free amino acids and peptides whereby the weight ratio of free amino acids to peptides is about 1:1 and wherein at least about 50 molar % of the peptides has a molecular weight of 400 Da or less. This composition may be rich in one or more branched-chain amino acid-(BCAA-) and or glutamine-containing di- or tripeptides. Also, the invention relates to the use of a water soluble protein-containing aqueous fraction obtained from a wet-milling process or the protein hydrolysate in: the manufacture of a medicament for the treatment or prevention of a condition associated with inappropriate blood sugar metabolism; aiding recovery and/or endurance during or after exercise; stimulating the generation of lean body mass; infant nutrition; or the preparation of a food or feed composition or a food or feed supplement. | 11-11-2010 |
Anna Roos, Amsterdam NL
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20130236494 | VACCINATION AGAINST INFLUENZA - Described are methods for vaccinating a subject against influenza comprising administering a vaccine multiple times to a subject where the vaccine comprises influenza hemagglutinin (HA) and neuraminidase (NA) proteins from at least a first influenza strain, wherein the HA and NA proteins of the first influenza strain are administered to the subject at least three times within a period of less than one year. Such immunization schemes induce cross-protection against heterologous and heterosubtypic influenza strains. | 09-12-2013 |
Dirk Roos, Amsterdam NL
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20090263795 | DIAGNOSTIC METHODS INVOLVING DETERMINING GENE COPY NUMBERS AND SNPs IN THE FcyRII/FcyRIII GENE CLUSTER, AND PROBES FOR USE IN SUCH METHODS TO DETECT SUSCEPTIBILITY TO AND TREATMENT EFFICACY IN AUTOIMMUNE DISEASES - The invention relates to diagnostic methods to predict whether a subject is predisposed for acquiring a disease or to predict the therapy responsiveness of an individual patient. Provided is a method for determining whether a subject is predisposed for developing an autoimmune disease, comprising determining in a sample isolated from said subject the amount of intact genes, or gene products thereof, of the FcγRII/FcγRIII gene cluster, said gene cluster comprising the FCGR2C, FCGR3A, FCGR2A and FCGR3B genes encoding an activating FcγR, and FCGR2B encoding an inhibitory Fcγ R; and correlating said amount to the amount observed in a healthy population. Also provided is a method to predict the responsiveness of a subject to therapy with intravenous immunoglobulin (IVIg) therapy or a monospecific biological, such as a humanized or human monoclonal antibody or a chimeric molecule, comprising the C-terminal Fc-tail of IgG. | 10-22-2009 |
20110189672 | DIAGNOSTIC METHODS INVOLVING DETERMINING GENE COPY NUMBERS AND SNPs IN THE FcyRll/FcyRlll GENE CLUSTER, AND PROBES FOR USE IN SUCH METHODS TO DETECT SUSCEPTIBILITY TO AND TREATMENT EFFICACY IN AUTOIMMUNE DISEASES - The invention relates to diagnostic methods to predict whether a subject is predisposed for acquiring a disease or to predict the therapy responsiveness of an individual patient. Provided is a method for determining whether a subject is predisposed for developing an autoimmune disease, comprising determining in a sample isolated from said subject the amount of intact genes, or gene products thereof, of the FcγRII/FcγRIII gene cluster, said gene cluster comprising the FCGR2C, FCGR3A, FCGR2A and FCGR3B genes encoding an activating FcγR, and FCGR2B encoding an inhibitory FcγR; and correlating said amount to the amount observed in a healthy population. Also provided is a method to predict the responsiveness of a subject to therapy with intravenous immunoglobulin (IVIg) therapy or a monospecific biological, such as a humanized or human monoclonal antibody or a chimeric molecule, comprising the C-terminal Fc-tail of IgG. | 08-04-2011 |
Johanna Roos, Katwijk NL
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20080286803 | Method for the Functional Determination of Mannan-Binding-Lectin Associated Serine Proteases (Masps) and Complexes Thereof - This invention relates to the field of determining, assaying or quantifying activity of components of the complement system. More particularly, the invention relates to methods for detecting the presence or level of activity in a sample of mannan-binding-lectin associated serine proteases (MASPs) or complexes of such proteases with lectins and to detection of the particular lectins themselves. Provided is a method for determining the activity of a MASP in a sample, comprising incubating the sample with a pro-urokinase comprising at its activation site the consensus sequence Arg/Leu/Gly-Yyy-Arg/Lys-Ile/Leu/Val-Zzz-Gly-Gly cleavable by a MASP, wherein Yyy can be any amino acid and Zzz is preferably an aliphatic amino acid, and determining proteolytic activation of said pro-urokinase. | 11-20-2008 |
Johannes Adrianus Roos, Doetinchem NL
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20140302272 | BALLISTIC RESISTANT ARTICLE COMPRISING POLYETHYLENE TAPES - A ballistic-resistant moulded article containing a compressed stack of sheets that contain high molecular weight polyethylene tapes. The direction of the polyethylene tapes within the compressed stack is not unidirectional. At least part of the tapes have a width of at least 2 mm, a thickness to width ratio of at least 10:1, and a density of at most 99% of the theoretical tape density. The moulded article is made of tapes that have a density below the theoretical density of the tapes. | 10-09-2014 |
Rein Andre Roos, Delft NL
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20140367478 | SYSTEM AND METHOD FOR DELIVERING SPRAYED PARTICLES BY ELECTROSPRAYING - A spraying device for producing a spray of particles in a carrier gas at ambient pressure, includes a storage volume for a liquid substance; at least one nozzle having an inlet and an outlet, the nozzle inlet fluidly communicating with the storage volume; a counter electrode; an electric supply coupled between the at least one nozzle and counter electrode for providing a first potential and create a first electric field between the nozzle outlet and the counter electrode. The device further includes at least one discharge electrode coupled to the electric supply for providing a second potential between the discharge electrode and the counter electrode, the polarity of the second potential being opposite to the polarity of the first potential. The at least one nozzle and the at least one discharge electrode are arranged adjacent and parallel to each other and facing the counter electrode from a substantially same direction. | 12-18-2014 |
Reinder Wietse Roos, Utrecht NL
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20090168037 | Lithographic apparatus and device manufacturing method - An immersion lithographic projection apparatus is disclosed. The apparatus includes a substrate table for holding a substrate and a liquid supply system for supply liquid to the substrate. The apparatus is constructed and arranged to allow the liquid to flow off the substrate and over at least two edges of a top surface of the substrate table. The geometry of the edge may be optimized to reduce a static thickness of a layer of liquid on the top surface. | 07-02-2009 |
20090168042 | Lithographic apparatus and device manufacturing method - An immersion lithographic projection apparatus is disclosed. The apparatus includes a substrate table for holding a substrate, the substrate table being constructed and arranged to allow liquid to flow off the substrate and over an edge of a top surface of the substrate table, and a gutter for collecting the liquid flow under the edge. Several features for improving liquid retrieval are described. | 07-02-2009 |
Steven Roos, Eindhoven NL
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20100050164 | PIPELINED PROCESSOR AND COMPILER/SCHEDULER FOR VARIABLE NUMBER BRANCH DELAY SLOTS - Different numbers of delay slots are assigned by a compiler/scheduler to each different type of jump operation in a pipelined processor system. The number of delay slots is variable and kept to the minimum needed by each type of jump operation. A compatible processor uses a corresponding number of branch delay slots to exploit the difference in predictability of different types of branch or jump operations. Different types of jump operations resolved their target addresses in different numbers of delay slots. As a result, the compiler/scheduler is able to generate more efficient code than for a processor with a fixed number of delay slots for all jump types, resulting in better processor performance. | 02-25-2010 |
Willem Frederik Roos, Hoensbroek NL
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20120187223 | PROCESS FOR PRODUCING GRANULES - The present invention relates to a process for the production of granules from a liquid composition with a decreased dust production, said process comprising the steps of: applying the liquid composition onto solid particles that are kept in a continuous movement by a gas stream in a granulation zone of an oblong granulator, thereby depositing and solidifying said liquid composition around said solid particles to increase the size of the particles and thereby form grown solid particles; discharging a stream of said grown solid particles from the granulation zone, dividing, in a size-sorting apparatus, said stream of said grown solid particles into individual streams based on the size of said grown solid particles to thereby produce streams of undersized, oversized, and desired-sized grown solid particles; transferring said stream of said oversized grown solid particles to a size-reducing apparatus; crushing said stream of said oversized grown solid particles in said size-reducing apparatus, thereby reducing the particle size of said oversized grown solid particles and thereby producing a stream of crushed solid particles wherein that said stream of crushed solid particles is introduced in the granulator at a place below the place where the gas stream leaves the granulator. | 07-26-2012 |
20120231277 | PROCESS FOR PRODUCING GRANULES - The present invention relates to a process for the preparation of granules comprising the steps of: providing a granulation zone comprising particles, the particles being kept in motion; providing a first feed stream comprising a liquid composition into the granulation zone, the liquid composition being applied onto or over the moving particles in the granulation zone; withdrawing a product stream comprising granules from the granulation zone, the granules being the result of layered growth of the moving particles in the granulation zone; wherein a second feed stream comprising granulation nuclei is fed into the granulation zone, wherein the granulation nuclei have a particle size distribution characterized by a standard deviation of the particle size that is less than 15% of the mean particle size, and wherein the second feed stream comprises between 0.05 wt % and 50 wt % of the product stream. | 09-13-2012 |