Patent application number | Description | Published |
20100129794 | Magnetic Polymer Particles - The present invention relates to magnetic polymer particles including magnetic particles selected from the group of ferromagnetic, ferrimagnetic and/or superparamagnetic particles, where the magnetic particles are embedded in a crosslinked polyacrylate or polyalkylacrylate matrix. | 05-27-2010 |
20110054054 | HYDRAZINE-MODIFIED MATRICES AND USE THEREOF IN METHODS FOR ISOLATING BIOMOLECULES - The invention relates to novel functionalized matrices or matrix materials comprising structures of general formula Carrier-Linker-Spacer-NR | 03-03-2011 |
20110071031 | COMPOSITIONS, METHODS, AND KITS FOR ISOLATING AND ANALYZING NUCLEIC ACIDS USING AN ANION EXCHANGE MATERIAL - The present disclosure relates to methods for isolating, amplifying, and/or analyzing nucleic acids in the presence of an anion exchange material by performing the isolation, amplification and/or analysis step in the presence of at least one anionic compound. | 03-24-2011 |
20110076751 | LYSIS, BINDING AND/OR WASH REAGENT FOR ISOLATING AND/OR PURIFYING NUCLEIC ACIDS - The present invention relates to a lysis, binding and/or wash reagent for isolating and/or purifying nucleic acids and a method for isolating and/or purifying nucleic acids. | 03-31-2011 |
20110105739 | NOVEL MATRIX MATERIALS, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF IN METHODS FOR ISOLATING BIOMOLECULES - The invention relates to functionalized matrix materials or matrices that have structures of general formula (I) T-(C═O)O—B-D, methods for the production thereof, and the use thereof in methods for purifying and isolating biomolecules. | 05-05-2011 |
20110186524 | Porous Ferro- or Ferrimagnetic Glass Particles for Isolating Molecules - Porous, ferro- or ferrimagnetic, glass particles are described that selectively bind molecules of interest, especially nucleic acid molecules; under appropriate conditions. Methods of preparing the porous, ferro- or ferrimagnetic, glass particles and their use for identifying or separating molecules of interest are also described. Kits comprising the porous, ferro- or ferrimagnetic, glass particles are also provided. | 08-04-2011 |
20110318784 | PREPARATION AND AMPLIFICATION OF NUCLEIC ACIDS BY MEANS OF MAGNETIC PARTICLES - The invention relates to the preparation of a biological sample for performing verifications and examinations, wherein the aim of the invention is the creation of a method for preparing a biological sample having an improved PCR sensitivity compared to the reference standard having standard PCR without having to raise the cost thereof. | 12-29-2011 |
20110319506 | NUCLEIC ACID PURIFICATION METHOD - The present invention relates to a method for purifying nucleic acids using a nucleic acid-binding phase which is furnished with a deficit of nucleic acid-binding groups A having a pK of 8 to 13, or which has groups A and binding-inhibiting groups N which are neutrally charged during the binding, and preferably during the elution, and the method comprises the following steps: (a) binding the nucleic acids to the nucleic acid-binding phase at a pH which is below the pH of the pK of the nucleic acid-binding groups A (binding pH); (b) eluting the nucleic acids at a pH which is above the binding pH (elution pH). In addition, corresponding kits and also nucleic acid-binding phases which can be used for purifying nucleic acids are disclosed. The technology according to the invention permits the purification of nucleic acids and, in particular, elution, with use of low salt concentrations, and so the purified nucleic acids can be directly processed, for example used in a PCR. | 12-29-2011 |
20120077969 | NUCLEIC ACID PURIFICATION METHOD - The present invention relates to a method for purifying a defined amount of nucleic acids from a nucleic acid-containing sample, which has at least the following steps: (a.) contacting the nucleic acid-containing sample with a defined amount of a nucleic acid binding phase with the following features: (i) the nucleic acid binding phase has nucleic acid binding ligands that have at least one protonatable group; (ii) the nucleic acid binding ligands are bound to a carrier; (iii) the nucleic acid binding phase has a surface with a low charge density, wherein the amount of nucleic acids in the sample exceeds the binding capacity of the amount of nucleic acid binding phase used; (b.) binding of the nucleic acids to the nucleic acid binding phase at a pH (binding pH) that is below the pKs value of at least one of the protonatable groups; (c.) elution of the nucleic acids at a pH that is above the binding pH, wherein a defined amount of nucleic acids is obtained. Furthermore, corresponding kits and nucleic acid binding phases, which can be used for the purification of nucleic acids, are disclosed. | 03-29-2012 |
20120245337 | NUCLEIC ACID PURIFICATION METHOD - The present intimation relates to a method for purifying nucleic acids from a sample containing nucleic acids, the method comprising at least the following steps: a. bringing the sample containing nucleic acids into contact with a nucleic acid binding phase comprising protonatable groups, wherein the protonatable groups have a pKa value of 9 to 12; b. binding the nucleic acids to the nucleic acid phase at a pH (binding pH) that is at least one pH unit less than the pKa value of at least one of the protonatable groups; c. eluting the nucleic acids at a pH greater than the binding pH but at least one pH unit less than the pKa value of at least one of the protonatable groups. Also disclosed are corresponding kits and nucleic acid binding phases that can be used for purifying nucleic acids. | 09-27-2012 |
Patent application number | Description | Published |
20100261289 | WATER-SOLUBLE POLYMERS HAVING CHELATORS - The present invention relates to a functionalized polymer having a high solubility in at least one solvent having high E | 10-14-2010 |
20130023655 | METHOD FOR PRECIPITATING ANIONIC SURFACTANT IONS IN THE PRESENCE OF NUCLEIC ACIDS - The present invention relates to a method for selectively precipitating anionic surfactant ions from a liquid sample comprising anionic surfactant ions and nucleic acids, as well as to a kit for the isolation and purification of nucleic acids. | 01-24-2013 |
20130030163 | METHOD FOR ISOLATING AND PURIFYING NUCLEIC ACIDS - The present invention relates to a method for isolating and purifying nucleic acids, preferably comprising genomic DNA, from biological samples comprising the steps of lysing the sample using a lysis buffer comprising a source of anionic surfactant ions, optionally disintegrating the RNA present in the lysate, precipitating the surfactant ions from the lysate, and separating the nucleic acids from the precipitate and further contaminants by size-exclusion chromatography. The invention furthermore relates to a lysis buffer, a method of lysing cells and a kit for the isolation and purification of nucleic acids. | 01-31-2013 |
20130030165 | CHROMATOGRAPHIC DEVICE AND METHOD FOR ISOLATING AND PURIFYING NUCLEIC ACIDS - The present invention relates to a chromatographic device for isolating and purifying nucleic acids, preferably genomic DNA, by gel filtration chromatography, a method for isolating and purifying nucleic acids, preferably genomic DNA, using this device and a kit comprising this device. | 01-31-2013 |
20130158247 | METHOD FOR ISOLATING AND/OR PURIFYING NUCLEIC ACID(S) - The present invention relates to a method for isolating and/or purifying one or more nucleic acid(s) from a sample, comprising the steps of essentially separating the nucleic acid(s) from the sample by binding the nucleic acid(s) to a solid phase by means of a non-chaotropic water-soluble binding ligand at a first pH (pH I), and essentially eluting the nucleic acid(s) from the solid phase at a second pH (pH II). The invention further relates to a kit for isolating and/or purifying nucleic acid(s) from a sample and/or for protecting nucleic acid(s). | 06-20-2013 |
20140243216 | METHODS FOR SEPARATING NUCLEIC ACIDS BY SIZE - The present invention pertains to a method for isolating nucleic acids by size from a sample comprising nucleic acids of different sizes using an anion exchange matrix, wherein nucleic acids of a preselected size or a preselected size range are isolated by varying the pH value during elution and/or binding. | 08-28-2014 |