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Rodesch, WI

Matthew Rodesch, Stoughton, WI US

Patent application number	Description	Published
20090105081	METHODS AND SYSTEMS FOR SOLUTION BASED SEQUENCE ENRICHMENT - The present invention provides methods and systems for the capture and enrichment of target nucleic acids and analysis of the enriched target nucleic acids. In particular, the present invention provides for the enrichment of targeted sequences in a solution based format.	04-23-2009
20090221438	METHODS AND SYSTEMS FOR UNIFORM ENRICHMENT OF GENOMIC REGIONS - The present invention provides methods and compositions for the enrichment of target nucleic acids in a microarray system. In particular, the present invention provides methods and compositions for uniform enrichment of target nucleic acid molecules in a microarray format. The present invention also provides for intentionally non-uniform enrichment among target nucleic acid molecules.	09-03-2009
20100222232	ENRICHMENT AND SEQUENCE ANALYSIS OF GENOMIC REGIONS - The present invention provides novel methods for reducing the complexity of preferably a genomic sample for further analysis such as direct DNA sequencing, resequencing or SNP calling. The methods use pre-selected immobilized oligonucleotide probes to capture target nucleic acid molecules from a sample containing denatured, fragmented (genomic) nucleic acids for reducing the genetic complexity of the original population of nucleic acid molecules.	09-02-2010
20100331204	METHODS AND SYSTEMS FOR ENRICHMENT OF TARGET GENOMIC SEQUENCES - The present invention provides methods and systems for targeted nucleic acid sequence enrichment in a sample. In particular, the present invention provides for enriching for targeted nucleic acid sequences during hybridizations in hybridization assays by first depleting non-target nucleic acid sequences.	12-30-2010
20120046175	METHODS AND SYSTEMS FOR SOLUTION BASED SEQUENCE ENRICHMENT - The present invention provides methods and systems for the capture and enrichment of target nucleic acids and analysis of the enriched target nucleic acids. In particular, the present invention provides for the enrichment of targeted sequences in a solution based format.	02-23-2012
20120238477	METHODS FOR SYNTHESIS OF AN OLIGOPEPTIDE MICROARRAY - An oligopeptide microarray and methods for the synthesis thereof are presented. Further presented is a microarray on a solid support comprising at least about 10,000 oligopeptide features per cm	09-20-2012
20120245057	WHOLE PROTEOME TILING MICROARRAYS - The present invention relates to a microarray comprising at least 50,000 oligopeptide features per cm	09-27-2012

Matt J. Rodesch, Madison, WI US

Patent application number	Description	Published
20100016178	METHODS FOR RAPID PRODUCTION OF TARGET DOUBLE-STRANDED DNA SEQUENCES - It has been previously disclosed that DNA segments can be made in massively parallel chemical synthesis operations on a common substrate followed by release of the segments from the substrate and assembly of the segments into target DNA molecules. Here it is taught that if the DNA primary constructs are sufficiently long and properly designed, that the copy numbers of the primary constructs can be multiplied as needed by a PCR process using as a template regions at the ends of the primary constructs. The end regions, called flanking regions, can also be designed so that they may be cleaved easily from the amplification products. The target double-stranded DNA can then be assembled from the cleaved fragments. Hundreds of thousands of oligonucleotides can be synthesized and assembled into many different individual genes by this process in a relatively quick and efficient process.	01-21-2010