Rocco D.
Rocco D. Gogliotti, Kingston Springs, TN US
Patent application number | Description | Published |
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20100120858 | Piperidine Derivatives - The invention relates to compounds of Formula (I) | 05-13-2010 |
20110172227 | ALKYL 3-((2-AMIDOETHYL)AMINO)-8-AZABICYCLO[3.2.1]OCTANE-8-CARBOXYLATE ANALOGS AS SELECTIVE M1 AGONISTS AND METHODS OF MAKING AND USING SAME - In one aspect, the invention relates to compounds having a general structure: | 07-14-2011 |
20110319429 | SUBSTITUTED 1,1,3,1-TETRAOXIDOBENZO[D][1,3,2]DITHIAZOLES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION - Compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) and methods of using the compounds. | 12-29-2011 |
20120245153 | MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION - Compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) and use thereof. | 09-27-2012 |
20130040944 | MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION - Pyrrole compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction. | 02-14-2013 |
20130096110 | Pyrazolopyridine, Pyrazolopyrazine, Pyrazolopyrimidine, Pyrazolothiophene and Pyrazolothiazole Compounds as MGLUR4 Allosteric Potentiators, Compositions, and Methods of Treating Neurological Dysfunction - Pyrazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction. | 04-18-2013 |
20130158078 | Heterocyclic Sulfone MGLUR4 Allosteric Potentiators, Compositions, and Methods of Treating Neurological Dysfunction - Heterocyclic sulfone compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction. | 06-20-2013 |
20140371239 | MENIN-MLL INHIBITORS AND METHODS OF USE THEREOF - The present invention relates generally to compounds that inhibit the binding of menin and MLL or MLL fusion proteins and methods of use thereof. In particular embodiments, the present invention provides compositions comprising piperidine-containing compounds and methods of use thereof to inhibit the interaction of menin with MLL oncoproteins (e.g., MLL1, MLL2, MLL-fusion oncoproteins), for example, for the treatment of leukemia, solid cancers, diabetes, and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, MLL-PTD and/or menin. | 12-18-2014 |
Rocco D. Gogliotti, Nashville, TN US
Patent application number | Description | Published |
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20130065895 | Pyrazolopyridine, Pyrazolopyrazine, Pyrazolopyrimidine, Pyrazolothiophene and Pyrazolothiazole Compounds as MGLUR4 Allosteric Potentiators, Compositions, and Methods of Treating Neurological Dysfunction - Pyrazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction. | 03-14-2013 |
Rocco D. Pochy, Fremont, CA US
Patent application number | Description | Published |
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20090243807 | RFID System for Identifying Location of Sensors/Indicators - A system of identifying the source location that a particle counter is using to draw its data from. The present invention includes a transmitting sensor placed at the location of interest, and a receiving sensor placed on the particle-counter device. A receiving sensor communicates a new position when a particle counter is not replaced at its origination point. | 10-01-2009 |
20090246101 | Apparatus for Rapid Oxidation using UV Radiation - An apparatus employing a UV reaction chamber that produces light for levying high-level amounts of hydroxyl radicals during the oxidation process. The flow passes through a fluid intake and into the UV reaction chamber. A metallic coating on the outer shell and quartz reactor work for increased efficiency during the oxidation process, as does a coolant tube. The apparatus is connected to a number of conceivable systems as the apparatus aids in the rapid oxidation process of the water flow. | 10-01-2009 |
20090246882 | System for Measurement of Dissolved Organic Compounds in Water - A system for measuring dissolved organic compounds in water that engages separate conductivity and temperature sensors at various points in the water flow. In addition, a UV reaction chamber produces light that levies high-level amounts of hydroxyl radicals during the oxidation process. The flow is then diverted into various directions based upon the settings of a three-way valve that determines when the sensor readings will take place as the water flows through the UV radiation. | 10-01-2009 |
Rocco D. Pochy, Milpitas, CA US
Patent application number | Description | Published |
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20150077230 | Protection System for Instrument Service and Calibration - A system designed to maintain calibration and protect the location-based data acquired in measurements performed with a precise instrument. The system of the present invention is preferably implemented via an instrument that includes an RFID system. The RFID reader is preferably integrated into the measurement instrument itself, and is capable of reading RFID tags that are proximal to the instrument or are affixed to location information encoded within the RFID tags. | 03-19-2015 |
20150077860 | Beam Profile in Particle Counter - A particle counter system is disclosed having a linear diverging lens, preferably a Powell lens, in order to create a top-hat profile without a loss of beam energy. The particle counter system disclosed creates ideal beam intensity distribution across the ribbon of light originating from the laser diode of the particle counter. | 03-19-2015 |