Patent application number | Description | Published |
20100214768 | Light for a power tool and method of illuminating a workpiece - A power tool including a end effector rotatable with respect to the housing, a collar rotatable with respect to the housing, a printed circuit board (PCB) rotatably fixed with respect to the housing, and a light element operatively connected to the PCB and adjacent to the end effector and in a recess of the collar and located to illuminate a workpiece machined by the power tool. A method of providing light for a workpiece being machined by a power tool including locating lighting elements around a spindle of a power tool, aligning the lighting elements to shine light on a workpiece being machined by the power tool, operatively connecting the lighting elements to a PCB, containing and supporting the PCB with a guide, supporting wires configured to provide power to the PCB with the guide, locating the lighting elements, PCB and guide in a rotatable collar, and preventing the lighting elements, PCB and guide from rotating when the collar rotates. | 08-26-2010 |
20110058356 | POWER TOOL WITH LIGHT EMITTING ASSEMBLY - A power tool including an end effector rotatable with respect to the housing, a collar non-rotatably coupled to the housing, an annular printed circuit board (PCB) rotatably fixed with respect to the housing, and a light element operatively connected to the PCB and adjacent to the end effector and in a recess of the collar and located to illuminate a workpiece machined by the power tool. | 03-10-2011 |
20110188232 | POWER TOOL WITH A LIGHT FOR ILLUMINATING A WORKPIECE - A power tool having a light for illuminating an area proximate a movable end effector. The light may be mounted in such a way as to transmit light through a rotatable collar on the power tool, through or through a member of a housing of the power tool, or from the moving end effector. The light may be powered by a power source that is used for moving the end effector or from a generator that generates electrical power when the power tool is used. | 08-04-2011 |
20130003358 | Power Tool with Light for Illuminating a Workpiece - A power tool having a light for illuminating an area proximate a movable end effector. The light may be mounted in such a way as to transmit light through a rotatable collar on the power tool, through or through a member of a housing of the power tool, or from the moving end effector. The light may be powered by a power source that is used for moving the end effector or from a generator that generates electrical power when the power tool is used. | 01-03-2013 |
20130003359 | Light for a Power Tool and Method of Illuminating a Workpiece - A power tool including a end effector rotatable with respect to the housing, a collar rotatable with respect to the housing, a printed circuit board (PCB) rotatably fixed with respect to the housing, and a light element operatively connected to the PCB and adjacent to the end effector and in a recess of the collar and located to illuminate a workpiece machined by the power tool. A method of providing light for a workpiece being machined by a power tool including locating lighting elements around a spindle of a power tool, aligning the lighting elements to shine light on a workpiece being machined by the power tool, operatively connecting the lighting elements to a PCB, containing and supporting the PCB with a guide, supporting wires configured to provide power to the PCB with the guide, locating the lighting elements, PCB and guide in a rotatable collar, and preventing the lighting elements, PCB and guide from rotating when the collar rotates. | 01-03-2013 |
20130286635 | Power Tool with Light Emitting Assembly - A power tool includes a housing having a large diameter rear portion and a narrow diameter nosepiece. An end effector is rotatably coupled to the housing. A holder with a substantially annular holder body is received over the nosepiece and non-rotatably coupled to the housing. A substantially annular cover having at least one transparent surface, and an internal annular groove, is received at least partially inside the holder body, and non-rotatably and axially fixed with respect to the holder. A substantially annular printed circuit board is received at least partially inside the annular groove in the cover, and non-rotatably and axially fixed with respect to the cover. A plurality of lighting elements is operatively connected to the printed circuit board and radially disposed about the printed circuit board. The lighting elements are aligned with the at least one transparent surface so as to illuminate a workpiece. | 10-31-2013 |
20130301244 | Power Tool With Light For Illuminating Workpiece - A power tool having a light for illuminating an area proximate a movable end effector. The light may be mounted in such a way as to transmit light through a rotatable collar on the power tool, through or through a member of a housing of the power tool, or from the moving end effector. The light may be powered by a power source that is used for moving the end effector or from a generator that generates electrical power when the power tool is used. | 11-14-2013 |
Patent application number | Description | Published |
20080306148 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 12-11-2008 |
20120141578 | COMPOSITIONS AND METHODS RELATING TO PROLIFERATIVE DISEASES - Anti-cancer compositions and methods are described herein. In particular, compositions including one or more of leelamine, a leelamine derivative, abietylamine, an abietylamine derivative, and an abietic acid derivative are described. Methods for treatment of pathological conditions particularly cancer, in a subject using one or more of leelamine, a leelamine derivative, abietylamine, an abietylamine derivative, and an abietic acid derivative are described herein. | 06-07-2012 |
20130178523 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 07-11-2013 |
20130184339 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 07-18-2013 |
20130184340 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 07-18-2013 |
20130209546 | COMBINATORIAL METHODS AND COMPOSITIONS FOR TREATMENT OF MELANOMA - The invention relates to combining targeted therapies with selected chemotherapeutics for the treatment of melanoma. The invention provides a method for inducing apoptosis in a melanoma tumor cell by reducing Akt3 activity. A method for inducing apoptosis in a melanoma tumor cell comprising contacting a melanoma tumor cell with an agent that reduces Akt3 activity to restore normal apoptotic sensitivity to a melanoma tumor cell, allowing a lower concentration of chemotherapeutic agents resulting in decreased toxicity to a patient. Also disclosed is a method for treating a melanoma comprising administering an agent that reduces Akt3 activity and an agent that reduces V599E B-Raf activity, thereby treating a melanoma tumor. | 08-15-2013 |
20130217949 | COMBINATORIAL METHODS AND COMPOSITIONS FOR TREATMENT OF MELANOMA - The invention relates to combining targeted therapies with selected chemotherapeutics for the treatment of melanoma. The invention provides a method for inducing apoptosis in a melanoma tumor cell by reducing Akt3 activity, a method for inducing apoptosis in a melanoma tumor cell comprising contacting a melanoma tumor cell with an agent that reduces Akt3 activity to restore normal apoptotic sensitivity to a melanoma tumor cell, allowing a lower concentration of chemotherapeutic agents resulting in decreased toxicity to a patient. Also disclosed is a method for treating a melanoma comprising administering an agent that reduces Akt3 activity and an agent that reduces V599E B-Raf activity, thereby treating a melanoma tumor. | 08-22-2013 |
20130253052 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 09-26-2013 |
20140212475 | ANTI-CANCER COMPOSITIONS AND METHODS - Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor. | 07-31-2014 |
20140322304 | COMPOSITIONS AND METHODS RELATING TO PROLIFERATIVE DISEASES - Anti-cancer compositions and methods are described herein. In particular, compositions including one or more of leelamine, a leelamine derivative, abietylamine, an abietylamine derivative, and an abietic acid derivative are described. Methods for treatment of pathological conditions particularly cancer, in a subject using one or more of leelamine, a leelamine derivative, abietylamine, an abietylamine derivative, and an abietic acid derivative are described herein. | 10-30-2014 |
20140348901 | COMBINATORIAL METHODS AND COMPOSITIONS FOR TREATMENT OF MELANOMA - The invention relates to combining targeted therapies with selected chemotherapeutics for the treatment of melanoma. The invention provides a method for inducing apoptosis in a melanoma tumor cell by reducing Akt3 activity, a method for inducing apoptosis in a melanoma tumor cell comprising contacting a melanoma tumor cell with an agent that reduces Akt3 activity to restore normal apoptotic sensitivity to a melanoma tumor cell, allowing a lower concentration of chemotherapeutic agents resulting in decreased toxicity to a patient. Also disclosed is a method for treating a melanoma comprising administering an agent that reduces Akt3 activity and an agent that reduces V599E B-Raf activity, thereby treating a melanoma tumor. | 11-27-2014 |
20150265577 | ANTI-CANCER COMPOSITIONS AND METHODS - Compositions and pharmaceutical compositions including one or more selenium-containing COX-2 inhibitors are provided according to aspects of the present invention. Methods of treating a subject having or suspected of having cancer are provided according to aspects of the present invention which include administering a therapeutically effective amount of a pharmaceutical composition including a selenium-containing COX-2 inhibitor. | 09-24-2015 |
20150376124 | ANTI-CANCER COMPOSITIONS AND METHODS - Anti-cancer compositions and methods are described including one or more isothiocyanates and/or isoselenocyanates. Methods of treating a subject are provided according to embodiments of the present invention which include administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject having a condition characterized by Akt dysregulation. Administering a therapeutically effective amount of a composition including an isothiocyanate and/or isoselenocyanate to a subject detectably increases apoptosis and/or decreases proliferation of cancer cells, particularly cancer cells characterized by Akt dysregulation. | 12-31-2015 |
20160030366 | COMPOSITIONS AND METHODS INCLUDING LEELAMINE AND ARACHIDONYL TRIFLUOROMETHYL KETONE RELATING TO TREATMENT OF CANCER - The present invention relates to compositions and methods for treatment of proliferative disease. In specific aspects, the present invention relates to compositions including (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1-,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine (leelamine) and arachidonyl trifluoromethyl ketone (ATK) in combination; methods for treatment of cancer including administration of leelamine and ATK in a subject in need thereof; and particularly methods for treatment of skin cancer including administration of leelamine and ATK in a subject in need thereof. | 02-04-2016 |
20160045437 | COMPOSITIONS AND METHODS INCLUDING CELECOXIB AND PLUMBAGIN RELATING TO TREATMENT OF CANCER - The present invention relates to compositions and methods for treatment of proliferative disease. In specific aspects, the present invention relates to compositions including celecoxib and plumbagin in combination; methods for treatment of a proliferative disease including administration of celecoxib and plumbagin in a subject in need thereof; and particularly methods for treatment of skin cancer including administration of celecoxib and plumbagin in a subject in need thereof. | 02-18-2016 |
Patent application number | Description | Published |
20090169628 | ARTICLE AND METHOD FOR FOCUSED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC MATERIALS - A microfiber extrudate and delivery process includes a bio-compatible polymer matrix forming a body of the microfiber extrudate, an exogenously excitable material arranged within the body, and an active load arranged within the body. | 07-02-2009 |
20100078848 | SPINNERET AND METHOD OF SPINNING FIBER - Disclosed is a spinneret and a method of spinning. The spinneret includes a first pore configured for extruding a first component of a multi-component fiber, a second pore configured for extruding a second component of the multi-component fiber, and a thermal insulator positioned between the first pore and the second pore and configured for preventing heat from the first component from damaging the second component. The first component and the second component have incompatible thermal resistance. | 04-01-2010 |
20110076771 | TISSUE FIBER SCAFFOLD AND METHOD FOR MAKING - The present disclosure relates to a fiber, a method of forming a fiber, a system for forming a fiber, and a method of engineering tissue from a fiber. The fiber includes an engineered geometric feature forming a non-Euclidian geometry. | 03-31-2011 |
20110111225 | Extruded Filament Having High Definition Cross-Sectional Indicia/Coding, Microscopic Tagging System Formed Therefrom and Method of Use Thereof for Anti-Counterfeiting of Product Authentication - An extruded filament is provided having a cross-sectional configuration which permits a cut transverse section of the filament to function as a high definition tagging material, the extruded filament having contained therein along the direction of the longitudinal axis (the axis of extrusion) of the filament a multitude of extruded strand portions, which may be the same or different from one another from the standpoint of composition, visual or forensic effect, and which strand portions provide a multitude of pixel-like portions within a cross-sectional portion of the filament, which multitude of pixel-like portions, when taken together, comprise at least one pre-selected degree of identification whereby the tagging material may be differentiated or identified based on at least one degree of identification. A cut fiber or microparticle formed from the filament may be used to authenticate a product when used in association with the product. | 05-12-2011 |
20120093930 | ARTICLE AND METHOD FOR FOCUSED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC MATERIALS - A microfiber extrudate and delivery process includes a bio-compatible polymer matrix forming a body of the microfiber extrudate, an exogenously excitable material arranged within the body, and an active load arranged within the body. | 04-19-2012 |
Patent application number | Description | Published |
20140239609 | CARGO TRUCK MULTI-STAGE EXTENDABLE PERSONNEL PLATFORM - A personnel platform for installation on a cargo truck comprises a mounting bracket securely fastened to a framing structure of the cargo truck beneath a personnel door, a platform deck mounted to a sliding mechanism securely fastened to the mounting bracket, wherein the platform deck is operable to be slidably configured in a stowed position beneath the cargo truck and a deployed position extending substantially horizontally beyond the cargo truck, and a latching mechanism operable to lock the platform deck in one of the stowed position and the deployed position. | 08-28-2014 |
20150224936 | CARGO TRUCK MULTI-STAGE EXTENDABLE PERSONNEL PLATFORM WITH FOLDABLE GUARDRAIL - A personnel platform for installation on a cargo truck comprises a mounting bracket securely fastened to a framing structure of the cargo truck beneath a personnel door, a platform deck mounted to a sliding mechanism securely fastened to the mounting bracket, wherein the platform deck is operable to be slidably configured in a stowed position beneath the cargo truck and a deployed position extending substantially horizontally beyond the cargo truck, and a latching mechanism operable to lock the platform deck in one of the stowed position and the deployed position. The platform further includes a guardrail accessory stowable under the platform deck, the guardrail accessory having first and second elongated members rotatably coupled together at one end. A free end of the first elongated member being adapted to secure to the platform deck to form a substantially vertical post, and a free end of the second elongated member being adapted to secure to the open personnel door to form a substantially horizontal guardrail. | 08-13-2015 |
20150233408 | SELF-REAMING SELF-TAPPING FASTENER - A fastener comprises a driver head, an elongated shank having an unthreaded section coupled to the driver head and a threaded section terminating in a blunt end thereof, and at least two elongated flutes formed in the elongated shank extending over the threaded section and at least a portion of the unthreaded section. The elongated flutes are substantially triangular in cross-section with a vertex and two asymmetrical legs, one leg forming a cutting element adapted for reaming and cutting a thread in an opening having a diameter less than a major thread diameter of the threaded section. | 08-20-2015 |