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Roberts, MD
Beverly T. Roberts, Baltimore, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110220379 | HOUSING AND GEARBOX FOR DRILL OR DRIVER - A power tool with a handle housing, a motor, an output member and a cassette. The handle housing that defines a handle. The motor is received in the handle housing. The cassette is received in the handle housing and includes a transmission housing, a multi-stage transmission received in the transmission housing, and a rear thrust washer. The transmission housing has a first end with first and second circumferentially extending channels formed therein. The rear thrust washer has a body and first and second lock members that extend radially from the body. Each of the first and second lock members is received in an associated one of the first and second circumferentially extending channels. | 09-15-2011 |
Dale Charles Roberts, Halethorpe, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100045932 | Wireless scleral search coil including systems for measuring eye movement and methods related thereto - Featured is a wireless scleral search coil that includes one or more passive, resonant coils and in a particular embodiment two orthogonal, passive, resonant coils, where each coil resonates at a different frequency. Each resonant coil includes a coil-capacitor circuit, each circuit being configured to resonant at a different frequency. Such a wireless scleral search coil is disposed within a biocompatible material that is shaped to conform and rest upon the eye of a subject. Also featured are system including such a wireless scleral search coil, one or more transmitter coils, an assembly of one or more receiver coils and a calculating sub-system for processing signal data to obtain eye measurement information. | 02-25-2010 |
David D. Roberts, Bethesda, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20080249026 | PEPTIDES AND THEIR UTILITY IN MODULATION OF BEHAVIOR OF CELLS EXPRESSING alpha3beta1 INTEGRINS - The present invention relates to a peptide comprising the sequence R | 10-09-2008 |
| 20090203762 | METHODS FOR THE PRODUCTION OF BILIVERDIN - The present invention relates to compositions and methods for the production of biliverdin. In particular, the invention concerns methods for producing biliverdin in yeast, especially | 08-13-2009 |
| 20100092467 | PREVENTION OF TISSUE ISCHEMIA, RELATED METHODS AND COMPOSITIONS - Provided herein are compositions and methods for preventing, ameliorating, and/or reducing tissue ischemia and/or tissue damage due to ischemia, increasing blood vessel diameter, blood flow and tissue perfusion in the presence of vascular disease including peripheral vascular disease, atherosclerotic vascular disease, coronary artery disease, stroke and influencing other conditions, by suppressing CD47 and/or blocking TSP1 and/or CD47 activity or interaction. Influencing the interaction of CD47-TSP1 in blood vessels allows for control of blood vessel diameter and blood flow, and permits modification of blood pressure and cardiac function. Under conditions of decreased blood flow, for instance through injury or atherosclerosis, blocking TSP1-CD47 interaction allows blood vessels to dilate and increases blood flow, tissue perfusion and tissue survival. This in turn reduces or prevents tissue necrosis and death. The therapeutics identified herein allow for precise regulation of blood flow to tissues and organs which need it, while substantially avoiding systemic complications. Methods and compositions described herein can be used to increase tissue survival under conditions of trauma and surgery, as well as conditions of chronic vascular disease. Also disclosed are methods for the treatment of elderly subjects using agents that affect TSP1 and CD47 and thereby affect tissue perfusion. Additionally, provided herein are compositions and methods for influencing blood coagulation, allowing for controlled increased or decreased blood clotting. Additionally, provided herein are compositions and methods for decreasing blood flow, as in the case of cancer through mimicking the effects of TSP1 and CD47 on blood vessel diameter and blood flow. | 04-15-2010 |
| 20100112626 | Use of Semenogelin in the Diagnosis, Prognosis and Treatment of Cancer - Method of diagnosing cancer in a mammal comprising assaying a test sample from the mammal for an increased level of semenogelin, wherein the increased level of semenogelin in the test sample is diagnostic for the cancer; methods of prognosticating and assessing the effectiveness of treatment of a cancer in a mammal based on the level of semenogelin in a test sample; a composition comprising (a) an immune-response inducing effective amount of (i) semenogelin or polypeptide fragment thereof or (ii) antibody thereto or (b) a recombinant vector encoding and expressing an immune-response inducing effective amount of (i) or (ii); a method of inducing an immune response to a cancer in a mammal comprising administering to the mammal the foregoing composition. | 05-06-2010 |
| 20110009311 | PEPTIDES AND THEIR UTILITY IN MODULATION OF BEHAVIOR OF CELLS EXPRESSING ALPHA3 BETA1 INTEGRINS - The present invention relates to a peptide comprising the sequence R | 01-13-2011 |
| 20110135641 | RADIOPROTECTANTS TARGETING THROMBOSPONDIN-1 AND CD47 - Described herein is the discovery that cell and tissue survival can be dramatically increased following radiation exposure through inhibition of the interaction between TSP-1 and CD47. This effect is shown using antisense molecules, peptides, and antibodies, which can now be used as radioprotectant agents. These agents find application in minimizing, reducing and/or preventing tissue damage following intentional and accidental radiation exposure, as well as increasing the therapeutic efficacy of radiation therapies by protecting non-target tissue from incidental radiation damage and by increasing tumor ablation following radiation treatment. | 06-09-2011 |
| 20120142751 | METHODS FOR THE PRODUCTION OF BILIVERDIN - The present invention relates to compositions and methods for the production of biliverdin and methods of treatment and prevention. In particular, the invention concerns methods for producing biliverdin in yeast, especially | 06-07-2012 |
Delores M. Roberts, Capital Heights, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110076652 | READING GAME - An apparatus and method to improve reading, particularly the reading of young children. The game objective is to score points by answering questions posed by sets of cards. The card set is determined by a spinner. This game is designed to help children to read fluently. | 03-31-2011 |
Delores Moment Roberts, Capitol Hgts., MD US
| Patent application number | Description | Published |
|---|---|---|
| 20080199836 | I-Read board game - I-READ is a board game designed to help children to read fluently, and to improve in critical thinking, problem solving, spelling, social skills and self esteem. The I-READ game can be used by all young children, ages 6-12, as a learning tool at home, in schools, early learning centers, after school and tutoring programs and libraries. Used frequently to help increase test scores. | 08-21-2008 |
Gary D. Roberts, Huntington, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090237247 | REMOTE AREA MONITORING SYSTEM - A Remote Area Monitoring System (RAMS) for detecting movement in a disallowed direction through a passageway (P). The RAMS monitors two volumetric spaces that are established by the system, both of which spaces are defined with respect to depth, width, and height. Both a warning zone and an alarm zone are defined for each space. The warning zone protects against inadvertent incursion into the protected spaces; while the alarm zone protects against intentional intrusions thereinto by movement in the disallowed direction. The RAMS automatically monitors both zones and does not require human vigilance to detect and warn of an incursion or intrusion. Human traffic, in both directions through the zones, is monitored; as well as the movement of objects. Movement of humans is detected using a sensor ( | 09-24-2009 |
Guy Roberts, Potomac, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100127870 | Detecting Loading and Unloading of Material - An apparatus and techniques for detecting the loading and unloading of materials on a mobile structure are disclosed. The techniques can be used to detect when material is on a support structure of the mobile structure and to detect when the material is off the support structure of the mobile structure. | 05-27-2010 |
Guy P. Roberts, Potomac, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20120169569 | INTEGRATED ANTENNA ACTIVITY MONITOR SYSTEM AND METHOD - The present disclosure provides an integrated antenna activity monitor system and method that provides an integrated activity indicator for the antenna by tapping a portion of the radio frequency (RF) energy from the antenna and utilizing the RF energy to drive the integrated activity indicator. In an exemplary embodiment, the integrated activity indicator circuit comprises an impedance matching network, a high-frequency rectifier circuit, and a light emitting diode. The impedance matching network is coupled to an antenna feed of the antenna, and configured to tap a portion of radio frequency energy from the antenna feed. The high-frequency rectifier circuit is coupled to the impedance matching network, and the light emitting diode coupled to an output of the high-frequency rectifier circuit. | 07-05-2012 |
Jack C. Roberts, Columbia, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090029150 | Impact Resistant Flexible Body Device - An impact resistant device is provided comprising a support matrix and a plurality of energy absorbing elements operatively connected to the support matrix, each element comprising at least one ceramic material and at least one strain rate sensitive material. The impact resistant device can be worn as body armor to protect the wearer from high velocity projectiles. | 01-29-2009 |
Jay B. Roberts, Silver Spring, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100011431 | METHODS AND APPARATUS FOR AUTHORIZING ACCESS TO DATA - In one embodiment, a method comprises receiving a request from a first party for access to controlled data, and providing access to the controlled data to a second party. The first party requests access to the controlled data and a token is provided to the first party. The token includes data associated with authorized access to the controlled data. A request for access to the controlled data including the token is later received from the second party, and access to the controlled data is provided to the second party. | 01-14-2010 |
| 20100100950 | CONTEXT-BASED ADAPTIVE AUTHENTICATION FOR DATA AND SERVICES ACCESS IN A NETWORK - A method includes sending a command set to a client module via a network, receiving via the network a context identifier and a data set associated with the command set, verifying the command set, and authenticating the client module. The command set is verified based on the data set. The client module is authenticated based on the context identifier. A service is made accessible to the client module after the authenticating, The service is inaccessible to the client module before the authenticating. | 04-22-2010 |
Jeff Roberts, Rockville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20100135902 | PAPILLOMAVIRUS PSEUDOVIRUSES FOR DETECTION AND THERAPY OF TUMORS - Disclosed herein are methods of detecting tumors, monitoring cancer therapy, and selectively inhibiting the proliferation and/or killing of cancer cells utilizing a papilloma pseudovirus or a papilloma virus-like particle (VLP) | 06-03-2010 |
Jeffrey N. Roberts, Rockville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110091496 | METHODS AND COMPOSITIONS FOR THE DELIVERY OF VACCINES TO DISRUPTED EPITHELIUM - The invention features immunogenic compositions and methods useful for eliciting an immune response. In preferred embodiments, papillomavirus or adenovirus vectors are used to elicit exceptionally potent antibody and T cells responses in disrupted epithelium. The methods are useful in preventing or treating a subject having a disease or an infection. In particular examples, the methods are useful for preventing or treating a viral infection. | 04-21-2011 |
Michael S. Roberts, Walkersville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090081161 | Treatment of neoplasms with viruses - The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy. | 03-26-2009 |
Michael S. Roberts, Myersville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110117060 | CANCER TREATMENT USING VIRUSES, FLUOROPYRIMIDINES AND CAMPTOTHECINS - Mammalian subjects having a neoplasm are treated with a virus, a fluoropyrimidine, for example 5-fluorouracil, and a camptothecin compound. The virus is selected from the group consisting of a Newcastle disease virus, a measles virus, a vesicular stomatitis virus, an influenza virus, a Sindbis virus, a picornavirus, and a myxoma virus. | 05-19-2011 |
Raymond G. Roberts, Montgomery Village, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090184889 | Method and apparatus for displaying - Aspects of the disclosure provide a display system. The display system can include a display module having a configurable optical characteristic that varies from substantially transmissive to substantially reflective, at least one data capturing device configured to capture data to form a display image, and at least a first projector configured to project the display image to the display module. Therefore, the display image can be overlaid with a real image according to an optical configuration of the display module. | 07-23-2009 |
Steve Roberts, Potomac, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090155289 | FURIN-CLEAVABLE PEPTIDE LINKERS FOR DRUG-LIGAND CONJUGATES - Disclosed are certain peptide linkers for conjugating drugs to ligands, and the resulting drug-linker-ligand molecules and compositions thereof. The conjugated molecules useful for the targeted delivery of drugs to the desired cells, and allow for the intracellular release of the drug in cases where the targeted antigen is internalized via the trans Golgi network and not the lysosomal pathway. | 06-18-2009 |
Steven F. Roberts, Bethesda, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110027321 | Chlamydia Vaccine Comprising HtrA Polypeptides - The present invention provides vaccine compositions useful in prevention and treatment of | 02-03-2011 |