Roberts, GB
Adrian Roberts, Nottinghamshire GB
Patent application number | Description | Published |
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20090229993 | Treatment Process For Concrete - A single anode system used in multiple electrochemical treatments to control steel corrosion in concrete comprises a sacrificial metal that is capable of supporting high impressed anode current densities with an impressed current anode connection detail and a porous embedding material containing an electrolyte. Initially current is driven from the sacrificial metal [ | 09-17-2009 |
20110168571 | TREATMENT PROCESS FOR CONCRETE - A single anode system used in multiple electrochemical treatments to control steel corrosion in concrete. The anode system comprises a sacrificial metal that is capable of supporting high impressed anode current densities with an impressed current anode connection detail and a porous embedding material containing an electrolyte. Initially current is driven from the sacrificial metal ( | 07-14-2011 |
20130118916 | TREATMENT PROCESS FOR CONCRETE - A single anode system used in multiple electrochemical treatments to control steel corrosion in concrete comprises a sacrificial metal that is capable fo supporting high impressed anode current densities with an impressed current anode connection detail and a porous embedding material containing an electrolyte. Initially current is driven fromt eh sacrificial metal [ | 05-16-2013 |
Adrian Roberts, Nottingham GB
Patent application number | Description | Published |
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20080230398 | Sacrificial Anode and Backfill - The installation and use of embedded sacrificial anodes to protect reinforced concrete may be improved. In one example a cavity [ | 09-25-2008 |
Adrian Roberts, Chilwell GB
Patent application number | Description | Published |
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20110303530 | SACRIFICIAL ANODE AND BACKFILL - The installation and use of embedded sacrificial anodes to protect reinforced concrete may be improved. In one example a cavity [ | 12-15-2011 |
20130118897 | SACRIFICIAL ANODE AND BACKFILL COMBINATION - An anode and backfill steel protector combination for inserting into at least one cavity which is mechanically formed in steel reinforced concrete. The anode and the backfill steel protector combination comprises an anode for insertion into the at least one cavity with the anode comprising a sacrificial metal element less noble than steel and a backfill which comprises a viscous and pliable ionically conductive material for insertion into the at least one cavity. The backfill is packaged within a cartridge and the cartridge is a cartridge for use with a cartridge which facilitates injecting the backfill from the cartridge into the at least cavity formed in the concrete. The backfill in a cartridge has a shelf life of at least 2 days. | 05-16-2013 |
Andrew Roberts, Woodley GB
Patent application number | Description | Published |
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20080301977 | TOE STRAP PROTECTOR, AND FOOTWEAR COMPRISING SAID PROTECTOR - The present invention relates to a protector for a toe strap of a footwear such, in particular in the form of a shoe, a sandal or a flip-flop, comprising a tube or a tube-like body with a first end and an opposite second end along its longitudinal axis, in particular in the form of a circumferential sleeve, which at least partially encloses a space, with a first opening at the first end and an opposite second opening at the second end for the at least partial inclusion of a toe strap, wherein an inner wall of the tube or tube-like body extends from the first to the second end and wherein an outer wall extends from the first to the second end, wherein the tube or tube-like body, in particular the circumferential sleeve, comprises a slit extending from the first end to the second end and from the outer to the inner wall so that the tube or tube-like body, in particular the circumferential sleeve, comprises adjacent longitudinal first and second areas, in particular contact areas which are facing each other and wherein the tube or tube-like body comprises an elastomeric material. | 12-11-2008 |
Andrew Roberts, West Sussex GB
Patent application number | Description | Published |
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20080286281 | CD25 BINDING MOLECULES FOR THE USE IN THE TREATMENT OF MANIFESTATIONS OF REJECTION IN TRANSPLANTATION - Administration of monoclonal antibodies specific for IL-2R to xenograft recipients, or long-term to immunosuppression-intolerant or non-compliant patients over a period of time beyond the very early phase of organ transplantation, prevents transplant rejection. | 11-20-2008 |
Andrew Roberts, Berkshire GB
Patent application number | Description | Published |
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20110232129 | CUSHIONING PAD FOR A HUMAN FOOT, AN INSOLE AND A SHOE COMPRISING SAID PAD, AND A METHOD FOR THE MANUFACTURE OF SAID INSOLE - Pad for the ball regions of a human foot adapted to be placed in a shoe beneath a foot of a wearer of the shoe having a dimension in the heel to toe direction (X axis), a dimension in the outside to inside direction (Y axis) and a dimension in the down to up direction (Z axis) and comprising a front side surface and a back side surface, wherein the pad comprises at least two different zones, at least one first zone located on the X axis towards the toe direction and adapted for the support of the ball regions relating to at least three adjacent toes, in particular to all five toes of a human foot, and at least one adjacent second zone located on the X axis towards the heel direction, wherein the first zone has an average thickness greater than that of the second zone, wherein the second zone is tapered in the Z dimension in a toe to heel direction, wherein the front side surface of the first zone exhibits a pattern of protruding elements adapted for the massaging of the foot of the wearer, and wherein the first and second zones are comprising an elastomeric material. | 09-29-2011 |
Anthony Roberts, Brandon GB
Patent application number | Description | Published |
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20090121185 | METHOD OF FORMING A COMPOSITE CONTAINING A MATRIX COMPONENT AND AT LEAST ONE LIQUID CRYSTAL COMPONENT - A method of forming a composite containing a matrix component and at least one liquid crystal component includes providing a matrix, providing a first material that is phase separable from the matrix, adding the first material to the matrix, and replacing the first material that is phase separable form the matrix with a second material exhibiting liquid crystalline behavior. | 05-14-2009 |
Bryan Roberts, Leicestershire GB
Patent application number | Description | Published |
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20080293742 | Novel N-(Fluoro-Pyrazinyl)-Phenylsulfonamides as Modulators of Chemokine Receptor Ccr4 - The invention provides N-(fluoro-pyrazinyl)-phenylsulfonamides of formula (I) wherein R | 11-27-2008 |
20090023746 | COMPOUNDS AND THEIR USES 707 - The present invention relates to isoquinolinone derivatives of formula (I): | 01-22-2009 |
Bryan Roberts, Loughborough GB
Patent application number | Description | Published |
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20100081670 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES - The invention provides N-pyrazinyl-phenyl-sulphonamides of formula (I) for use in the treatment of chemokine mediated diseases. Particularly inflammatory diseases, such as asthma. | 04-01-2010 |
20100144759 | NOVEL N-(FLUORO-PYRAZINYL)-PHENYLSULFONAMIDES AS MODULATORS OF CHEMOKINE RECEPTOR CCR4 - The invention provides N-(fluoro-pyrazinyl)-phenylsulfonamides of formula (I) | 06-10-2010 |
Bryan Glyn Roberts, Loughborough GB
Patent application number | Description | Published |
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20100099665 | ISOQUINOLINONE DERIVATIVES - The present invention relates to isoquinolinone derivatives of formula (I): | 04-22-2010 |
Christopher Digby Roberts, West Midlands GB
Patent application number | Description | Published |
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20100194325 | ELECTRIC MOTOR CONTROL - A control system for an electric motor comprises processing means arranged to perform a control process which includes monitoring electrical voltages applied to the motor and electrical currents in the motor, and determining from them the rotational position of the motor. The system is further arranged to monitor at least one parameter of the control process thereby to detect a stall condition of the motor. | 08-05-2010 |
Christopher I. Roberts, Cheshire GB
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20120035800 | Vehicle Diagnostic, Communication and Signal Delivery System - A diagnostic tool that includes components that allow the diagnostic tool to record data while the vehicle is driven in order to capture data for intermittent faults. The diagnostic tool can operate in harsh conditions such as high and low temperatures. The diagnostic tool includes a capacitor to power the diagnostic tool in order to prevent complete drainage of the vehicle battery. The diagnostic tool includes a support module that can couple with a socket and a plug in order to keep them mated together during use. | 02-09-2012 |
20120035804 | Diagnostic Tool with Recessed Connector - A diagnostic tool that includes components that allow the diagnostic tool to record data while the vehicle is driven in order to capture data for intermittent faults. The diagnostic tool can operate in harsh conditions such as high and low temperatures. The diagnostic tool includes a capacitor to power the diagnostic tool in order to prevent complete drainage of the vehicle battery. The diagnostic tool includes a support module that can couple with a socket and a plug in order to keep them mated together during use. | 02-09-2012 |
Clive J. Roberts, Nottingham GB
Patent application number | Description | Published |
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20110189299 | PHARMACEUTICAL COMPOSITION CONTAINING SURFACE-COATED MICROPARTICLES - The invention provides a pharmaceutical composition that can be used for efficient administration of low-molecular weight drugs and polymeric compounds such as peptides and proteins by methods other than injection, as well as a method for producing the composition. The pharmaceutical composition is for transmucosal administration and comprises (a) a drug having a positive or negative charge at a predetermined pH, (b) a pharmaceutically acceptable small particle and (c) a pharmaceutically acceptable surface-coating polymer capable of being electrically charged at the pH, wherein the surface of the small particle is coated by the surface-coating polymer, the drug is immobilized on the surface of the small particle via the surface-coating polymer, and a complex is formed by a noncovalent interaction between the small particle and the surface-coating polymer and a concurrent electrostatic interaction between the surface-coating polymer and the drug. | 08-04-2011 |
20120244196 | PHARMACEUTICAL COMPOSITION CONTAINING MEDICAMENT-CONTAINING FINE PARTICLES AND METHOD FOR PRODUCING SAME - The invention provides a pharmaceutical composition that can be used for an efficient administration of a water-soluble polymer drug by a method other than injection, and a method for production of the pharmaceutical composition. The pharmaceutical composition contains a small particle comprised of (a) a water-soluble drug and (b) a pharmaceutically acceptable ionic crystalline compound which is solid at room temperature, wherein the ionic crystalline compound is crystallized in the small particle. | 09-27-2012 |
Craig Roberts, Glasglow GB
Patent application number | Description | Published |
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20110229531 | ANTI-PROTOZOA COMPOUNDS - Use of a compound in the control of growth of at least one organism of the order of Amoebida, wherein said compound is capable of modulating the histidine biosynthesis pathway, and/or the methionine biosynthesis pathway and/or a pathway branching from the histidine biosynthesis pathway and/or methionine biosynthesis pathway in said organism. | 09-22-2011 |
Craig William Roberts, Glasgow GB
Patent application number | Description | Published |
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20080249051 | Antimicrobial Compounds - The present invention relates to compounds that modulate the shikimate pathway and/or a pathway branching from the shikimate pathway in members of the Amoebida Order. In particular these compounds may be useful in the treatment or prevention of diseases caused or contributed to by members of the Amoebida Order. | 10-09-2008 |
20110245324 | ANTIMICROBIAL COMPOUNDS - The present invention relates to compounds that modulate the shikimate pathway and/or a pathway branching from the shikimate pathway in members of the Amoebida Order. In particular these compounds may be useful in the treatment or prevention of diseases caused or contributed to by members of the Amoebida Order. | 10-06-2011 |
Damon Roberts, Hampshire GB
Patent application number | Description | Published |
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20110176125 | SYSTEM AND METHOD FOR MONITORING BENDING OF A FLEXIBLE RISER - A system and method for monitoring bending curvature of a flexible pipe structure, including at least one conduit configured to conform to a profile of a bend stiffener of a flexible pipe structure, and the at least one conduit including one or more sensors, wherein each sensor is configured for measuring a bending curvature of the bend stiffener. | 07-21-2011 |
20110178730 | Flexible Pipe Fatigue Monitoring Below the Bend Stiffener of a Flexible Riser - A flexible pipe fatigue monitoring system | 07-21-2011 |
Damon Roberts, Southampton GB
Patent application number | Description | Published |
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20110259115 | STRUCTURAL LOAD MONITORING USING COLLARS AND CONNECTING ELEMENTS WITH STRAIN SENSORS - A system and method for measuring loads on a pipe, including a pair of collars that can be secured around the outer surface of the pipe to be monitored in an axially spaced relationship; and a connecting element having a strain gauge is fixed to the collars such that when the collars are secured to the pipe, the connecting element is arranged to measure distortion of the pipe due to applied loads, wherein the ends of the connecting element are attached to the collars such that when the collars are secured to the pipe, the ends of the connecting element are fixed against axial and circumferential movement relative to the pipe. The system includes the apparatus mounted on a pipe, such as a flexible pipe, in a subsea oil or gas installation. | 10-27-2011 |
Damon Richard Roberts, Hampshire GB
Patent application number | Description | Published |
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20120099097 | SYSTEM AND METHOD FOR UNIFORM AND LOCALIZED WALL THICKNESS MEASUREMENT USING FIBER OPTIC SENSORS - A system and method are provided for determining wall thickness of a structure such as a metallic pressurized pipe. The system includes an optical fiber having a plurality of Fiber Bragg Gratings (FBGs), and a mounting for securing the FBGs over discrete portions of the exterior surface of the pipe such that strain in the pressurized pipe wall is transmitted to the FBGs. The system further includes a light source and a light sensor coupled to an end of the optical fiber. The light sensor converts light reflected back from the FBGs into electrical signals that a digital processor converts into strain measurements. The FBGs are mounted around portions of the pipe expected to have significant metal loss as well as portions of the pipe expected to have negligible metal loss. The method includes at least one of comparing relative strains at locations with negligible metal loss to those with significant metal loss to accurately determine the thickness of the wall with metal loss; compensating for temperature effects by considering relative strains at areas of the pipe with and without metal loss; and measuring axial strain on the pipe with one or more of the FBGs to correct for at least one of bending and torsion effects on hoop strain. | 04-26-2012 |
20120192982 | FLEXIBLE PIPE TERMINAL END-ATTACHMENT DEVICE - A terminal end-attachment device ( | 08-02-2012 |
Dannielle Frances Roberts, Sandwich GB
Patent application number | Description | Published |
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20100010040 | Triazol Derivatives Useful For The Treatment of Diseases - The invention relates to compounds of formula (1) | 01-14-2010 |
Dave Roberts, Warrington GB
Patent application number | Description | Published |
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20110022521 | Authentication arrangement and method for use with financial transaction - A system and method for generating an authentication token which is used by an issuer associated with a integrated circuit card to authenticate a transaction. A personal card reader receives data, including an authentication cryptogram, from the integrated circuit card. The personal card reader uses the data received from the integrated circuit card to select one of at least two default bitmaps stored in a memory portion of the personal card reader. The personal card reader uses the selected default bitmap and the authentication cryptogram to build the authentication token. | 01-27-2011 |
20140365776 | Electronic Authentication Systems - A transaction device for establishing a shared secret with a point of interaction (POI) over a communications network to enable encrypted communications between the transaction device and the point of interaction, the device comprising: an input arranged to receive communications from the point of interaction; a processor arranged to generate a first communication according to a Diffie-Hellman protocol; an output arranged to send the first communication to the point of interaction; wherein the processor is arranged to apply a randomly generated blinding factor, r, when generating the first communication and wherein, in response to receiving a second communication from the point of interaction at the input, the second communication having been generated according to the Diffie-Hellman protocol, the processor is arranged to apply the randomly generated blinding factor and generate a shared secret according to the Diffie-Hellman protocol in dependence on data contained within the second communication. | 12-11-2014 |
Dave Anthony Roberts, Appleton Warrington GB
Patent application number | Description | Published |
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20090185687 | Systems and Methods for Mutual Authentication Using One Time Codes - Methods and systems for mutual authentication and personalizing a transaction device, such as a payment, transaction, or identity card. Successively generated one time codes are calculated by a first and second entity. One of the codes is transmitted to the second entity, which verifies the code is proper, then encrypts a second one time code using a third one time code and transmits the encrypted data to the first entity. The first entity decrypts the data using the third one time code, verifies the encrypted second one time code is proper, thereby mutually authenticating, and establishing a shared encryption key for subsequent communications, including transmission of personalization data. | 07-23-2009 |
20120303960 | Systems and Methods for Mutual Authentication Using One Time Codes - Methods and systems for mutual authentication and personalizing a transaction device, such as a payment, transaction, or identity card. Successively generated one time codes are calculated by a first and second entity. One of the codes is transmitted to the second entity, which verifies the code is proper, then encrypts a second one time code using a third one time code and transmits the encrypted data to the first entity. The first entity decrypts the data using the third one time code, verifies the encrypted second one time code is proper, thereby mutually authenticating, and establishing a shared encryption key for subsequent communications, including transmission of personalization data. | 11-29-2012 |
David Anthony Roberts, South Croydon GB
Patent application number | Description | Published |
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20120076269 | Radiotherapy Apparatus - The present invention provides a radiotherapy apparatus for applying therapeutic radiation to a target region of a patient, comprising a patient support, a source of radiation, a collimator comprising a plurality of leaves, a sensing system and control circuitry. The position of a target region is determined and resolved into two components orthogonal to the radiation beam axis. One component is assigned to the patient support, and the other to the collimator leaves, such that movement of the target region is compensated for and the radiation beam intersects is correctly targeted. | 03-29-2012 |
David John Roberts, Stockton-On-Tees GB
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20130041670 | SPEECH COMMAND INPUT RECOGNITION SYSTEM FOR INTERACTIVE COMPUTER DISPLAY WITH INTERPRETATION OF ANCILLARY RELEVANT SPEECH QUERY TERMS INTO COMMANDS - In an interactive computer controlled display system with speech command input recognition and visual feedback including means for predetermining a plurality of speech commands for respectively initiating each of a corresponding plurality of system actions in combination with means for providing for each of the plurality of speech commands an associated set of speech terms, each term having relevance to its associated command Also included are means responsive to a detected speech term having relevance to one of the speech commands for displaying a relevant command. The system preferably may display basic speech commands simultaneously along with relevant commands. The means for providing the associated set of speech terms may comprise a stored relevance table of universal speech input commands and universal computer operation terms conventionally associated with system actions initiated by the input commands, and means for relating operation terms of the system with terms in the relevance table. | 02-14-2013 |
David John Howard Roberts, Leeds GB
Patent application number | Description | Published |
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20080261960 | Biologically active methylene blue derivatives - The present invention relates to a phenothiazinium compound of Formula (I): | 10-23-2008 |
20080268033 | BIOLOGICALLY ACTIVE METHYLENE BLUE DERIVATIVES - The present invention relates to a phenothiazinium compound of Formula (I): | 10-30-2008 |
20080275033 | BIOLOGICALLY ACTIVE METHYLENE BLUE DERIVATIVES - A phenothiazinium compound of Formula (I) | 11-06-2008 |
20080312219 | Biologically active methylene blue derivatives - The present invention relates to a phenothiazinium compound of Formula (I): | 12-18-2008 |
20120302557 | BIOLOGICALLY ACTIVE METHYLENE BLUE DERIVATIVES - The present invention relates to a method of photodynamic therapy and to a method of inducing a photocytoxic effect which comprises applying to an area to be treated an effective amount of a compound of formula | 11-29-2012 |
David Keith Roberts, Crawley GB
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20110128444 | METHOD AND DEVICE FOR GENERATING AND DETECTING FINGERPRINTS FOR SYNCHRONIZING AUDIO AND VIDEO - This invention relates to a device and a method of generating a first and a second fingerprint ( | 06-02-2011 |
20120016876 | METHOD AND DEVICE FOR GENERATING AND DETECTING A FINGERPRINT FUNCTIONING AS A TRIGGER MARKER IN A MULTIMEDIA SIGNAL - A device is configured to perform a method that detects a trigger marker for an action corresponding to a segment of a multimedia signal. A fingerprint is generated based on the segment of the multimedia signal at a trigger time point. The generated fingerprint is stored in a database and communicated to the device. During playback of the multimedia signal, fingerprints of segments of the multimedia signal are generated and matched against fingerprints in the database. When a match is found, one or more associated actions for the segment are retrieved by the device. The trigger time point may be determined as a time point near or at the segment of the multimedia signal with the matched fingerprint. In this way, trigger markers for actions may be enabled without modifying the multimedia signal. | 01-19-2012 |
20140169505 | SPACE-TIME/SPACE-FREQUENCY CODING FOR MULTI-SITE AND MULTI-BEAM TRANSMISSION - The present invention relates to space-time or space-frequency coding in cellular systems. The same data is transmitted from different antennas with different coverage areas, corresponding to different cells. The different data streams have different parts of the space-time block codes applied. A mobile terminal can combine the different parts of the space-time block codes in different received signals. This provides better performance than the known techniques for single frequency networks. The invention can also be applied to antennas with different coverage areas from the same site, and different beams formed with antenna arrays. | 06-19-2014 |
D. K. Roberts, Crawley GB
Patent application number | Description | Published |
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20090190681 | SPACE-TIME/SPACE-FREQUENCY CODING FOR MULTI-SITE AND MULTI-BEAM TRANSMISSION - The present invention relates to space-time or space-frequency coding in cellular systems. The same data is transmitted from different antennas with different coverage areas, corresponding to different cells. The different data streams have different parts of the space-time block codes applied. A mobile terminal can combine the different parts of the space-time block codes in different received signals. This provides better performance than the known techniques for single frequency networks. The invention can also be applied to antennas with different coverage areas from the same site, and different beams formed with antenna arrays. | 07-30-2009 |
Edward P.l. Roberts, Chester GB
Patent application number | Description | Published |
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20090321361 | ADSORBENTS FOR TREATING CONTAMINATED LIQUIDS - An adsorbent particulate product for treating contaminated fluid and capable of electrochemical regeneration. The product includes unexpanded intercalated graphite in particulate form, in the form of flakes or in powder form. | 12-31-2009 |
20100251890 | TREATMENT OF CONTAMINATED GASES - A contaminant is removed from a gas in a method in which the gas is contacted with a solvent for the contaminant, and the resultant solution is contacted with intercalated graphite onto which the contaminant is adsorbed. The solvent will normally comprise water, and may itself be a contaminated liquid. In a preferred method the solvent is in a reservoir with particulate intercalated graphite; the contaminated gas is delivered to the base of the reservoir; and the gas rises in the solvent mobilizing the intercalated graphite in the reservoir. | 10-07-2010 |
20120118829 | TREATMENT OF CONTAMINATED LIQUIDS - Contaminants are removed from a quantity of contaminated liquid in a treatment reservoir ( | 05-17-2012 |
20120228230 | ADSORPTION OF CONTAMINANTS FROM LIQUID AND ELECTROCHEMICAL REGENERATION OF ADSORBENT - A method for the treatment of a liquid. The method comprises contacting the liquid within a treatment zone with an adsorbent material, which is then electrochemically regenerated within a regeneration zone following contact with said liquid. A disinfectant precursor species is provided within the regeneration zone and then electrochemically converted to a disinfectant species which can then contact adsorbent material and/or liquid within the regeneration zone effecting in-situ disinfection and resulting in the presence of residual disinfectant species in the treated liquid. There is further provided apparatus for carrying out such a method. | 09-13-2012 |
Edward P. L. Roberts, Chester GB
Patent application number | Description | Published |
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20090242488 | APPARATUS FOR THE ELECTROCHEMICAL REGENERATION OF ABSORBENTS - Apparatus for treating liquid by contact with a particulate adsorbent material comprises a regeneration chamber ( | 10-01-2009 |
20120304857 | TREATMENT OF CONTAMINATED GASES - A contaminant is removed from a gas in a method in which the gas is contacted with a solvent for the contaminant, and the resultant solution is contacted with intercalated graphite onto which the contaminant is adsorbed. The solvent will normally comprise water, and may itself be a contaminated liquid. In a preferred method the solvent is in a reservoir with particulate intercalated graphite; the contaminated gas is delivered to the base of the reservoir; and the gas rises in the solvent mobilizing the intercalated graphite in the reservoir. | 12-06-2012 |
Emily Jane Roberts, Cheshire GB
Patent application number | Description | Published |
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20120022110 | PHARMACEUTICAL DEPOT FOR 5-FLUORO-2-[[(1S)-1-(5-FLUORO-2-PYRIDYL)ETHYL]AMINO]-6-[(5-ISOPROPOXY-1H-- PYRAZOL-3-YL)AMINO]PYRIDINE-3-CARBONITRILE - A pharmaceutical depot comprising (i) 5-fluoro-2-[[(1S)-1-(5-fluoro-2-pyridyl)ethyl]amino]-6-[(5-isopropoxy-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile, or a pharmaceutically-acceptable salt thereof, as a pharmaceutical agent (PA) and (ii) a polymer which degrades to create an acidic microclimate, wherein the PA is released from the polymer upon polymer degradation. | 01-26-2012 |
20140045895 | PHARMACEUTICAL DEPOT FOR 5-FLUORO-2-[[(1S)-1-(5-FLUORO-2-PYRIDYL)ETHYL]AMINO]-6-[(5-ISOPROPOXY-1H-- PYRAZOL-3-YL)AMINO]PYRIDINE-3-CARBONITRILE - A pharmaceutical depot comprising (i) 5-fluoro-2-[[(1S)-1-(5-fluoro-2-pyridyl)ethyl]amino]-6-[(5-isopropoxy-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile, or a pharmaceutically-acceptable salt thereof, as a pharmaceutical agent (PA) and (ii) a polymer which degrades to create an acidic microclimate, wherein the PA is released from the polymer upon polymer degradation. | 02-13-2014 |
Eric Thomas Eldon Roberts, North Wales GB
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20090047615 | ORTHODONTIC LIGATURE - An orthodontic ligature to be applied in fixed appliance orthodontic treatments, such as dental braces (also known as orthodontic braces), that eliminates friction at an archwire/bracket interface by forming a channel between a bracket and a ligature, an archwire being displaced in the channel, so as to facilitate tooth movement. | 02-19-2009 |
Gareth J. Roberts, Derby GB
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20110254390 | MOUNTING ARRANGEMENT FOR AN ELECTRICAL MACHINE - A mounting arrangement for locating a stator ( | 10-20-2011 |
Gareth Wyn Roberts, Great Shelford GB
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20080275912 | Computer-Assisted Means for Providing Personalised Healthcare Products - The present invention relates to a computer assisted method of providing a personalized assessment of supplement requirements for a human subject in which an individual's genotype is analysed for the presence of alleles at one or more genetic loci which may be associated with risk factors, and the alleles present compared to a first dataset comprising information correlating the presence of individual alleles at genetic loci with a lifestyle risk factor to provide a risk factor associated with the presence of particular alleles in order to generate a personalized assessment of nutritional and therapeutic supplement requirements, which may include a personalized supplementation formula. | 11-06-2008 |
Gldeon Roberts, Stone GB
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20120264435 | Apparatus and Method for Cell Reselection in a Radio Access Network - A method for cell reselection from a serving cell to another cell in a radio access network covering a geographical area divided into a plurality of cells, the method comprising: attempting to reselect to a first other cell with a higher rank value than the serving cell; setting up a channel on the first other cell and initiating a completion period; conditional on the completion period expiring before the first other cell is identified as being a suitable cell, receiving cell measurements for cells and creating a cell ranking list of the cells based on rank values of the cells; conditional on a second other cell having a higher rank value than the serving cell or first other cell, attempting to reselect to the second other cell. | 10-18-2012 |
Guy Roberts, Buckinghamshire GB
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20090089287 | Automatically verifying that anti-phishing URL signatures do not fire on legitimate web sites - A method and computer program product prevent false positives from occurring by reducing or preventing legitimate web site content from triggering matches to phishing black lists, but provides time and cost savings over manual review of black lists. A method implemented in a computer system for detecting false positives among a plurality of search patterns of web sites that include illegitimate content comprises accessing a first page of a legitimate web site, obtaining all links included in the first page, for each link included in the first page that points to a page on the web site, determining whether the link matches at least one of the plurality of search patterns, and for each link that matches the search pattern, indicating that the search pattern is a false positive. | 04-02-2009 |
Guy Roberts, Milton Keynes GB
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20090074008 | Multiple packet UDP data transfers - A method and computer program produce provide the capability to use UDP to send messages that include more data than can be handled by a single UDP packet. A method for performing data transfer implemented in a computer system comprises transmitting a request for data, receiving a response to the request for data comprising a portion of the requested data and an indication that additional data is available, and transmitting a request for additional data. | 03-19-2009 |
20090248814 | Increasing spam scanning accuracy by rescanning with updated detection rules - A method, system, and computer program product for processing email messages rescans emails messages that have already been scanned for spam and delivered to user inboxes with updated spam detection rules. This increases the accuracy of spam scanning and reduces the need for users to submit missed spam in emails that was not detected at the time the emails were received, but would subsequently be detected with newer anti-spam rules. A method of processing email messages comprises receiving email messages in a local inbox or in an inbox on an email server, or both, the received email messages having been scanned using spam detection rules to determine whether or not they include spam, obtaining updated spam detection rules, and rescanning at least some of the received email messages using the updated spam detection rules to determine whether or not they include spam. | 10-01-2009 |
20120246274 | METHOD AND COMPUTER PROGRAM PRODUCT UTILIZING MULTIPLE UDP DATA PACKETS TO TRANSFER A QUANTITY OF DATA OTHERWISE IN EXCESS OF A SINGLE UDP PACKET - A method and computer program produce provide the capability to use UDP to send messages that include more data than can be handled by a single UDP packet. A method for performing data transfer implemented in a computer system comprises transmitting a request for data, receiving a response to the request for data comprising a portion of the requested data and an indication that additional data is available, and transmitting a request for additional data. | 09-27-2012 |
Guy William Welch Roberts, Milton Keynes GB
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20130031111 | SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR SEGMENTING A DATABASE BASED, AT LEAST IN PART, ON A PREVALENCE ASSOCIATED WITH KNOWN OBJECTS INCLUDED IN THE DATABASE - A system, method, and computer program product are provided for segmenting a database based, at least in part, on a prevalence associated with known objects included in the database. In operation, a database including a plurality of known objects is identified. Additionally, the database is segmented into a plurality of segments. Furthermore, each of the plurality of known objects are assigned to one of the plurality of segments, based at least in part on a prevalence associated with each of the plurality of known objects. | 01-31-2013 |
20130276106 | SYSTEM, METHOD, AND COMPUTER PROGRAM PRODUCT FOR VERIFYING AN IDENTIFICATION OF PROGRAM INFORMATION AS UNWANTED - A system, method, and computer program product are provided for verifying an identification of program information as unwanted. In use, program information is identified as unwanted at a client. Furthermore, the identification of the program information as unwanted is verified, utilizing a communication between the client and a server. | 10-17-2013 |
Ian Stanley Roberts, Cheshire GB
Patent application number | Description | Published |
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20100062084 | Treatment Of Gastrointestinal Diseases - The present invention relates to compositions (including medicaments and nutritional products) for use in the prevention or treatment of gastrointestinal disease. Such compositions comprise a therapeutically effective amount of a less than or equal to 4 kDa soluble fraction derivable from potato juice. | 03-11-2010 |
20100215787 | Composition For The Treatment Of Gastrointestinal Diseases - The present invention relates to compositions (including medicaments and nutritional products) for use in the prevention or treatment of gastrointestinal disease. Such compositions comprise a therapeutically effective amount of an alcohol soluble fraction derivable from potato juice. | 08-26-2010 |
James Jonathan Welch Roberts, Southampton GB
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20130064792 | THERAPY FOR INFLUENZA LIKE ILLNESS - An agent selected from: (a) interferon-β (IFN-β); (b) an agent that increases IFN-β expression; or (c) a polynucleotide which is capable of expressing (a) or (b); for use in the treatment of individuals with lower respiratory tract illness that has developed during or following an established ILI, wherein said treatment is by airway delivery of said medicament. | 03-14-2013 |
James P Roberts, Derby GB
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20080319684 | Method and system for determining the torque induced in a rotating shaft - A method of determining the torque induced in a rotating shaft ( | 12-25-2008 |
20110194122 | CLEARANCE AND WEAR DETERMINATION APPARATUS - Apparatus is provided for determining the clearance between a member and a casing surface over and relative to which the member moves, e.g. in a gas turbine engine. The apparatus includes a main waveguide and a reference element that is provided at a position intermediate the proximal and distal ends, or at the distal end, of the waveguide. The transmitter/receiver is arranged to transmit an electromagnetic signal through the main waveguide and receive (i) a first portion of the electromagnetic signal reflected from the reference element, (ii) a second portion of the electromagnetic signal reflected from the casing surface, and (iii) a third portion of the electromagnetic signal reflected from the member, allowing the relative positioning of the reference element, the casing surface and the member to be simultaneously determined. | 08-11-2011 |
Jennifer Roberts, East Lothian GB
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20120128629 | METHOD OF LABELLING INTERFERONS WITH PEG - A method of site specific labelling of an interferon molecule is provided. The method comprises the steps: a) providing a label molecule comprising a PEG moiety having an aldehyde or ketone moiety; b) providing an interferon molecule having a C terminal hydrazide moiety; and c) allowing the aldehyde or ketone moiety of the PEG moiety to react with the C terminal hydrazide of the interferon molecule to form a labelled interferon molecule, which comprises a PEG moiety attached to the C terminus of the interferon molecule via a hydrazone bond. Interferon molecules labelled using such a method are also described. | 05-24-2012 |
Jonathan James Roberts, Wantage GB
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20120223191 | Short Landing Air Vehicle by the use of Rotating Wings - An air vehicle | 09-06-2012 |
Keith Roberts, Crawley GB
Patent application number | Description | Published |
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20080285675 | Multiple Antenna Transmission with Variable Diversity Gain - A MIMO transmitter has a modulator ( | 11-20-2008 |
Keith Roberts, Cheddar GB
Kris Jonathan Roberts, Hampshire GB
Patent application number | Description | Published |
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20110026872 | DEVICE FOR APPLYING A FIBER-OPTIC MONITORING SYSTEM TO A COMPONENT TO BE MONITORED - An adapter device for applying a fiber-optic monitoring system to a component to be monitored includes a shell adapted to surround the component to be monitored, the shell having a rounded exposed surface onto which a first optical fiber of the fiber-optic monitoring system can be wrapped. | 02-03-2011 |
Louise Jannette Roberts, Bebington GB
Patent application number | Description | Published |
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20100104612 | ANTIPERSPIRANT COMPOSITIONS - Fragrance leaches rapidly from capsules having shells made from cross linked gelatin into volatile silicone oils. Unfortunately such oils are much favoured for anhydrous antiperspirant compositions. The rate and extent of leaching can be ameliorated greatly or nearly halted by employing as carrier oil, an ester oil or an ether oil, even in the presence of a significant fraction of volatile silicone oil. Consequently, the capability of antiperspirant compositions to generate detectable fragrance over an extended period after application to the skin is improved by employing ester or ether oil as all or part of the carrier liquid in which the antiperspirant is suspended. | 04-29-2010 |
Mark Roberts, Glasgow GB
Patent application number | Description | Published |
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20100255033 | Non-toxic double mutant forms of pertussis toxin as adjuvants - The invention relates to the use of an antigen which is a non-toxic double mutant form of pertussis toxin for the manufacture of a vaccine composition for intranasal administration to induce an immune response against | 10-07-2010 |
Martin Roberts, Lancashire GB
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20080236030 | Fuel Additives - The invention provides a fuel additive compound represented by the general formula (I) | 10-02-2008 |
Matthew I. Roberts, Southampton GB
Patent application number | Description | Published |
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20120005286 | Application of System Level Policy in Message Oriented Middleware - One or more policies to be applied to a set of one or more messages in a message oriented middleware are defined. Metrics of the message oriented middleware are monitored. Application of a policy in response to a trigger condition being satisfied is initiated. Application of the policy applies actions across the set of one or more messages. | 01-05-2012 |
20120192205 | APPLICATION OF SYSTEM LEVEL POLICY IN MESSAGE ORIENTED MIDDLEWARE - One or more policies to be applied to a set of one or more messages in a message oriented middleware are defined. Metrics of the message oriented middleware are monitored. Application of a policy in response to a trigger condition being satisfied is initiated. Application of the policy applies actions across the set of one or more messages. | 07-26-2012 |
Matthew William Lewis Roberts, Oxfordshire GB
Patent application number | Description | Published |
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20100050558 | MODULAR CONSTRUCTION SYSTEM AND METHOD OF CONSTRUCTION - The invention relates to a modular construction system. In particular, but not exclusively, the invention relates to a construction system, including modules, which are capable of being used in a wide range of applications including buildings and various other structures. Prior systems included structured modules connected by means of flexible joints which were composed of cables. These allowed relative movement between walls of various units. Such systems were complex and expensive to manufacture An improved modular construction system overcame this problem by providing a plurality of structural elements of V-shaped or chevron-shaped cross section. These are adapted to be assembled in a cellular configuration by their similar form, size and by virtue of the elements having apertures. Any aperture may receive a connector, which permits an amount of relative movement between said elements in two-rotational degrees of freedom. | 03-04-2010 |
20100058676 | MODULAR CONSTRUCTION ELEMENTS - Various modular construction systems exist and these all have limitations of cost, adaptability and strength. Some were also complex and time consuming to assemble. The present invention overcomes these problems by providing a simple modular construction element ( | 03-11-2010 |
Mike Roberts, Bradley Stoke GB
Patent application number | Description | Published |
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20110145749 | METHOD AND APPARATUS FOR USER INTERFACE DISPLAYS - An approach for providing a user interface display, for example, with a first window that includes a first predefined area to present a status display control and a second predefined area that is separately defined in the first window to present a status display related to the status display control. Further providing, for example, the user interface display with a second window that includes the first predefined area to present the status display control and a third area that transparently presents the status display over content in the second window upon selection of the status display control. | 06-16-2011 |
Paul R. Roberts, Southampton GB
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20080262562 | Energy Harvester for an Implant Device - This invention relates to the use of an electromagnetic generator and a pressure bladder located within a biological body in such a position to take advantage of the pressure fluctuations found within that body to produce electrical power. The invention uses these pressure fluctuations to displace the moving parts of a generator, to produce electricity in accordance with the Faraday principal, to power implanted devices. | 10-23-2008 |
Paul R. Roberts, Derby GB
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20110194906 | MACHINE TOOL - A machine tool has a tool holder mounted to a platform, and a plurality of legs for connecting the platform to a workpiece. Each leg has joint systems which allow each leg to rotate relative to the platform and the workpiece and are also actuatable to alter the inter-joint distance. By alterations in the inter-joint distances of the legs the position and orientation of the tool holder relative to the workpiece is controllable. Each leg also has an attachment foot for removably attaching the leg to the workpiece. The provision of separate attachment feet avoids the need for a dedicated base for the machine tool so that it can be used in-situ and in confined and obstructed working environments. | 08-11-2011 |
Peter John Roberts, Oxford GB
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20110267612 | Hollow Core Photonic Crystal Fibre Comprising a Fibre Grating in the Cladding and Its Applications - An optical fibre is provided having a fibre cladding around a longitudinally extending optical propagation core. The cladding has a reflection region of a varying refractive index in the longitudinal direction. | 11-03-2011 |
20120133624 | DISPLAY PANEL - A display panel incorporates the functionality to determine the three dimensional position of a light reflecting or emitting object ( | 05-31-2012 |
20120147296 | PHOSPHOR-BASED DISPLAY - A phosphor-based multi-coloured display is provided which includes a spatial light modulator comprising an addressable array of apertures each corresponding to a respective sub-pixel in the display; an array of phosphor regions each indexed to a corresponding aperture of the spatial light modulator; and a backlight which provides quasi-monochromatic light to phosphor within each of the phosphor regions. The phosphor within each of the phosphor regions, upon being excited by the quasi-monochromatic light of the backlight, emits light having a colour different from a colour of the quasi-monochromatic light, through the corresponding aperture of the spatial light modulator. | 06-14-2012 |
20130033849 | BACKLIGHT - A backlight is provided for an at least partially transmissive display or another lighting application. The backlight comprises an array of primary light sources that emit downwards towards an arrangement of curved mirror surfaces. The light reflected by the mirror surfaces is collimated by an arrangement of lenses. The mirror surface shape, lens shape, primary light source positions and the separation between the lens and mirror surfaces are chosen to ensure a high degree of spatial uniformity as well as collimation. | 02-07-2013 |
Peter Miles Roberts, Horsham GB
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20100212405 | METHOD AND APPARATUS FOR PIPE TESTING - A method of testing pipes for use in making subsea pipelines comprises cutting a ring from one or more pipes of the type used to make the pipeline; forming flat, substantially parallel surfaces on the ends of the ring; providing means for measuring strain and deformation of the ring; mounting the ring in a pressure chamber such that the ends of the ring form seals with opposing walls of the chamber to isolate the inside of the ring from the outside; increasing the pressure outside the ring and measuring the strain and deformation on the ring as the pressure increases; and using the deformation and strain measurements to determine a wall thickness for pipes to be used for the pipeline. An apparatus for testing rings cut from pipes for use in making subsea pipelines, comprises first and second test chamber sections which, when placed together define a test chamber for receiving the ring to be tested; one or more sensors for measuring strain and deformation of the ring; sealing means located in the chamber for forming a seal against the ring when received in the chamber; means for clamping the first and second sections together to form the chamber and engage the sealing means against the ring when received in the chamber to form a pressure resistant seal between the inside and outside of the ring; and a fluid inlet port in one of the chamber sections to allow a pressurised fluid to be admitted to the chamber outside the ring when received in the chamber. | 08-26-2010 |
Peter Miles Roberts, Surrey GB
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20110236135 | METHOD AND APPARATUS FOR INSTALLING TIDAL BARRAGES - A method of and modifies for installing a barrage across a body of water for generating electricity from tidal or current flow, the barrage being formed from a series of modules ( | 09-29-2011 |
Philip Mark Shryane Roberts, Hampshire GB
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20110186771 | Composite Material - A composite materil comprises magnetic particles dispersed in electrically insulating material. The magnetic particles have an aspect ratio greater than 1 (preferably greater than 10) and a concentration sufficiently high to produce negative permeability. The magnetic particles may be magnetic flakes of reduced carbonyl iron of average diameter 50 μm, average thickness 1 μm and aspect ratio 50, the magnetic flakes being at least 25% by volume of the composite material. The magnetic flakes may be aligned to produce enhanced permeability. The electrically insulating material may be paraffin wax, particulate PTFE, or another polymer. To control permittivity, the composite material may include an electrically conducting component such as graphite or conductive coatings upon the magnetic flakes. | 08-04-2011 |
Philip Mark Shryane Roberts, Woodcote GB
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20120301642 | SMART WINDOW - A core-shell nanoparticle which includes a core formed of a transparent material and a shell including vanadium dioxide (VO | 11-29-2012 |
20140196488 | WATER HARVESTING DEVICE - An apparatus extracts water from the air using a single circuit of gas containing a compressor, a cooling element, a heat exchanger and an ion source, where a single stream of air is used to provide water and to pre-cool the inlet air. | 07-17-2014 |
Richard Roberts, Bedfordshire GB
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20100052816 | Signal Branch for Use in a Communication System - A signal branch for use in a communication system, in particular in a reflector antenna, for the transmission of microwave signals is provided. The signal branch includes a common signal wave guide for transmitting a transmission signal and a received signal that has one first end and one second end as well as an exterior and interior. Moreover, a plurality of transmission signal wave guides is provided for feeding the transmission signal, with the transmission signal wave guides being disposed on the exterior of the common signal wave guide in a symmetrically distributed manner and each being communicatively connected to the common signal wave guide. A plurality of receiver signal wave guides is provided for transmitting the received signal, with the receiver signal wave guides being symmetrically adjacent to the second end of the common signal wave guide and each being communicatively connected to the common signal wave guide. | 03-04-2010 |
Richard Roberts, Henfield GB
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20100049479 | Crush modelling - A method of determining the impact resistance of a structure including a crushable material comprises the steps of determining for one or more layers of a finite element of the material during an impact whether the element or layer thereof is to be treated as failing by crushing. If the element or layer is determined to fail by crushing, a load-bearing portion of the structure is defined and the load-bearing portion is treated for the purpose of subsequent calculations as exhibiting an ongoing resistance. | 02-25-2010 |
Sally Roberts, Powys GB
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20110118379 | INTERVERTEBRAL DISC AND INTRAOCULAR LENS - The invention relates to the use of an aqueous gel in the repair of or prevention of damage to soft tissue, the gel comprising an aqueous gel obtainable by polymerizing one or more olefinically unsaturated monomers comprising one or more phosphate, phosphonate, borate, sulphate and/or sulphonate groups. This is preferably used for intervertebral discs or a lens of an eye. Kits and syringes containing the components are also provided. | 05-19-2011 |
Sarah Elizabeth Roberts, Middlewich GB
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20120035929 | MESSAGING SYSTEM - The messaging system ( | 02-09-2012 |
Sarah Louise Roberts, Kingston-Upon-Thames GB
Patent application number | Description | Published |
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20090291876 | Fabric Softening Composition - A liquid fabric treatment composition comprising a cationic fabric softening agent and a water-soluble linear polymeric viscosity modifier represented by the formula: Z-Y-(X-Y) | 11-26-2009 |
Scott Roberts, Warwickshire GB
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20090076376 | Material For Electrical Isolation And Vibro-Acoustic Performance - The present invention provides a material for the construction of external coverings accessible by humans or animals. It aims to increase the breakdown voltage between a high voltage VRF, high frequency source of energy and the human or animal, by adaptation of materials and structures. According to an embodiment of the invention, a structure is provided for the cover | 03-19-2009 |
Simon Roberts, Hampshire GB
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20100249352 | Process for the Production of Diols - The invention relates to a process for the production of diols with a special structure which are characterized by formula (I). These diols are substances which, besides two OH groups, contain a C═C double bond so that they are suitable as monomers for the production of polymers. The process comprises hydrolyzing a corresponding cyclic precursor in aqueous medium in the presence of an acid dissolved in that medium, the hydrolysis being accompanied by the elimination of a carbonyl compound, and subsequently neutralizing the acid present in the reaction mixture with a base, the base having a pK | 09-30-2010 |
Simon Roberts, Romsey GB
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20120151453 | AUTOMATED DEBUGGING SYSTEM AND METHOD - system and method for automatically identifying a source of a run-time error in a computer system comprises a static analysis system (SAS), an instrumentation system (IS) and a post-execution analysis system (PEAS). The is arranged to generate static analysis data on computer program code (CPC) for the computer system, including information on possible behaviors of the CPC when executed. The IS is arranged to instrument the CPC by inserting marker triggers into the CPC that, generate a marker associated with each of a number of predetermined points in the CPC that would be reached during execution of the CPC. Each marker is, uniquely identifiable. The predetermined points are determined in dependence on the static analysis data. The PEASpost execution analysis system is arranged to processes data on a run-time error produced by execution of the instrumented CPC, wherein the generated markers and the static analysis data to identify the source of the run-time error. | 06-14-2012 |
Simon Nicholas Roberts, Doncaster GB
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20130052106 | PROCESS FOR THE PRODUCTION OF FERROUS SULPHATE MONOHYDRATE - The invention provides a process for the production of ferrous sulphate monohydrate which comprises: (a) reacting a source of iron with an aqueous solution of sulphuric acid in at least a first reaction vessel, to obtain a process liquor comprising ferrous sulphate and acid solution; and then (b) combining the process liquor with concentrated sulphuric acid in a mixing vessel, causing the solution to self crystallize, thus forming a slurry comprising crystalline ferrous sulfate monohydrate. The slurry can, if desired, then be converted to ferric sulphate. | 02-28-2013 |
Stephen John Roberts, Oxfordshire GB
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20110169951 | ESTIMATING STATES OF A PLURALITY OF TARGETS TRACKED BY A PLURALITY OF SENSORS - A method of estimating states of a plurality of targets tracked by a plurality of sensors. The method includes obtaining a plurality of data sets based on measurements taken by a plurality of sensors, each data set including information on states of a plurality of targets. The method then generates a plurality of target correlation data sets describing correlation of the targets within a first data set and at least one other data set. A Generalised Covariance Union (GCU) technique is used to merge at least some of the plurality of target correlation data sets to generate an estimate of the states of the plurality of targets. | 07-14-2011 |
Stephen John Roberts, Oxford GB
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20120089554 | ESTIMATING A STATE OF AT LEAST ONE TARGET USING A PLURALITY OF SENSORS - The method includes receiving a plurality of target observations from a respective plurality of sensors and using the target observations to compute target state estimates. Each of the target state estimates is assessed to check if it suffers from one of a set of modelled possible fault types. The target state estimates are adjusted to compensate for any modelled fault type when it is assessed to be suffering from that fault type. A reliability value is computed for each of the target state estimates and the target state estimates are fused together based on the computed reliability values to produce a fused target state estimate. | 04-12-2012 |
Thomas Roberts, Cambridgeshire GB
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20110153312 | METHOD AND COMPUTER SYSTEM FOR AUTOMATICALLY ANSWERING NATURAL LANGUAGE QUESTIONS - A computer system and method for automatically answering natural language questions. The system comprises an input to receive said natural language questions; a data store to record linked pairs of questions and corresponding answers; a matcher configured to compare a said received natural language question withsaid linked question and answer pairs and an output to transfer a said received natural language question to a researcher if no matches are found. The system may further comprise a system to link pairs of questions and corresponding answers into groups, to enable the generation of a prototypicalanswer for each group of pairs of questions and answers and to store said prototypicalanswers in said data store; wherein said matcher compares a said received naturallanguage question with a question in said data store having an associated prototypicalanswer and output said associated prototypical answer for said question in response to said matching. Alternatively, said matcher may be configured to output all linked question and answer pairs which matchsaid received natural language question. The system may be further adapted to distribute natural language questions to be answered to researchers by assigning unpopularity scores to each of said natural language questions. | 06-23-2011 |
Tomos Huw Roberts, Bangor GB
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20110295025 | PROCESS FOR THE PREPARATION OF CHOLYL-L-LYSINE - A process for the preparation of cholyl-L-lysine comprising the steps of: —(a) reacting N-ε-CBZ-cholyl-L-lysine with a hydrogen source in the presence of a catalyst in a solvent comprising one or more alkanols; (b) removing the catalyst; (c) optionally diluting the resulting reaction mixture with water and optionally adjusting the pH of the resultant reaction mixture to a pH less than or equal to about 4; (d) removing the bulk of the alkanol whilst ensuring that the alkanol content of the resultant mixture is maintained above about 3% w/w of the remaining mixture; (e) extracting the resultant mixture from step (d) with an organic solvent; (f) adjusting the pH of the aqueous layer to a pH of about 4.5 or greater to precipitate cholyl-L-lysine; (g) isolate the precipitate. | 12-01-2011 |
20120220787 | PROCESS FOR THE PREPARATION OF 5-/6-NITROFLUORESCEIN - A process for the preparation of a mixture of 3′,6′-dihydroxy-6-nitrospiro[2-benzofuran-3,9′-xanthene]-1-one and 3′,6′-dihydroxy-5-nitrospiro[2-benzofuran-3,9′- xanthene]-1-one comprising the steps of:- (a) reacting 4-nitrophthalic acid or 4-nitrophthalic anhydride with benzene-1,3-diol in methanesulphonic acid; (b) quenching the reaction in step (a) with a solvent to precipitate product; (c) isolating the precipitate; (d) heating the precipitate in water in order to hydrolyse any methansulphonic acid ester present. | 08-30-2012 |
Vanessa Roberts, Nant Peris GB
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20120232328 | DRUG ACTIVATION SYSTEM - The present invention discloses a drug activator carrier comprising: a) particles having a metallic or metallic oxide core prepared from a paramagnetic material, said metallic core being coated with a coating material selected from polymer, metal or metal oxide; b) a biological material, having reductase activity, bound onto the metal coating the particles of step a), and wherein said biological material is capable of activating non-toxic pro-drugs into active and toxic drugs suitable for treating a disease; said drug activator carrier allowing targeted delivery of the toxic drug. | 09-13-2012 |