| Patent application number | Description | Published |
| 20090008306 | EXTRACORPOREAL DIALYSIS READY PERITONEAL DIALYSIS MACHINE - A dialysis system includes: (i) a dialysate pump; (ii) a patient line having a connector configured to be attached to a peritoneal patient part; (iii) an extracorporeal circuit; (iv) a blood pump in fluid communication with the extracorporeal circuit; (v) a blood filter in fluid communication with the extracorporeal circuit; and (vi) a control unit configured and arranged to selectively perform a therapy which (a) the blood pump is deactivated and the dialysate pump is caused to pump dialysate through the patient line or (b) the blood pump is activated to pump blood to the blood filter and the dialysate pump is caused to pump dialysate to the filter/extracorporeal circuit and/or remove fluid from the filter. | 01-08-2009 |
| 20090012448 | FLUID DELIVERY SYSTEM WITH SPIKED CASSETTE - A fluid dispensing machine, such as a peritoneal dialysis or hemodialysis machine, includes a dispenser or cassette that pumps a medical fluid for dialysis or other treatments for patients. The machine includes and uses an autoconnect device for connecting containers of liquid, such as bags of dialysis fluid or medication fluids, to the machine, while maintaining the sterility of the connection. The autoconnect device removes the cap from the fluid bag and pierces a sealing membrane on tubing from the bag. This makes it easier for patients to receive treatment, especially home treatment. The cassettes preferably have tubing ports with integral spikes for piercing the membrane on tubing from bags of liquids. The ports may be staggered for sequential engagement with the spikes. Other embodiments are useful for dispensing other liquids from other types of dispensing or pumping machines. | 01-08-2009 |
| 20090012449 | FLUID DELIVERY SYSTEM WITH AUTOCONNECT FEATURES - A fluid dispensing machine, such as a peritoneal dialysis or hemodialysis machine, includes a dispenser or cassette that pumps a medical fluid for dialysis or other treatments for patients. The machine includes and uses an autoconnect device for connecting containers of liquid, such as bags of dialysis fluid or medication fluids, to the machine, while maintaining the sterility of the connection. The autoconnect device removes the cap from the fluid bag and pierces the scaling membrane on tubing from the bag. This makes it easier for patients to receive treatment, especially home treatment. Other embodiments are useful for dispensing other liquids from other types of dispensing or pumping machines. | 01-08-2009 |
| 20090012453 | MOBILE DIALYSIS SYSTEM HAVING SUPPLY CONTAINER DETECTION - A dialysis system includes a dialysis instrument including at least one pump actuator; a disposable cassette operable with the at least one pump actuator; a plurality of supply containers connected fluidly to the disposable cassette; and a cart which includes a rotatable bearing plate onto which the instrument and supply containers are loaded, the bearing plate allowing a patient to turn the instrument and supply containers relative to the cart for selective access to the instrument or the supply containers. | 01-08-2009 |
| 20090012454 | DIALYSIS SYSTEM HAVING NON-INVASIVE TEMPERATURE SENSING - A dialysis system includes a dialysis instrument; a disposable item configured to hold a dialysis fluid and including an at least substantially opaque portion and an at least substantially clear portion; at least one non-invasive temperature sensor mounted to the dialysis instrument so as to be pointed selectively at the at least substantially clear portion and the at least substantially opaque portion; and a processor configured to calculate a temperature of the dialysis fluid within the disposable item using (i) a first temperature measurement from the at least one sensor while pointed at the at least substantially opaque portion, and (ii) a second temperature measurement from the at least one sensor pointed at the at least substantially clear portion. | 01-08-2009 |
| 20090012455 | DIALYSIS SYSTEM HAVING SUPPLY CONTAINER AUTOCONNECTION - A dialysis system includes a dialysis instrument including at least one pump actuator; a disposable cassette operable with the at least one pump actuator, a plurality of supply lines connected to the disposable cassette, each supply line including a supply line connector and a supply line tip protector; a plurality of dialysis fluid containers, the dialysis fluid containers each including a solution line having a solution line connector and a solution line tip protector; and an auto-connection mechanism including a solution line connector holder, a supply line connector holder, one of the holders fixed, the other of the holders moveable, and a moveable tip protector remover. | 01-08-2009 |
| 20090012456 | DIALYSIS SYSTEM HAVING DISPOSABLE CASSETTE - A dialysis system includes a dialysis instrument; a disposable cassette, the cassette including a rigid portion defining at least one pumping chamber, a pouch fitted over the rigid portion, the pouch including at least one flexible sheet sealed so as to provide a sealed environment inside the pouch; and wherein the instrument is configured to press the at least one flexible sheet against the pumping chamber to seal the pumping chamber for operation. | 01-08-2009 |
| 20090012457 | DIALYSIS SYSTEM HAVING DISPOSABLE CASSETTE AND INTERFACE THEREFORE - A medical fluid flow control system includes an interface including a first pump area, the first pump area of the interface including a pneumatic actuator port and a gasket seal port; and a membrane gasket including a second pump area for mating with the first pump area, the second pump area including a blind section which covers the pneumatic actuator port when the gasket is mated with the interface, the second pump area further including an aperture, the aperture sized and positioned to seal around the gasket seal port, allowing a negative pressure to be applied through the gasket seal port to a flexible sheet of a pumping cassette. | 01-08-2009 |
| 20090012458 | DIALYSIS SYSTEM HAVING DUAL PATIENT LINE CONNECTION AND PRIME - A dialysis system includes a dialysis instrument; a disposable cassette operable with the dialysis instrument; a dual lumen patient line including dual lumens, the dual lumen patient line connected to the disposable cassette; and a priming sequence in which ends of the dual lumens are connected together, a first pump chamber of the disposable cassette pumps fluid through the dual lumens until fluid reaches a second pump chamber of the disposable cassette. | 01-08-2009 |
| 20090012461 | DIALYSIS SYSTEM HAVING DISPOSABLE CASSETTE AND HEATED CASSETTE INTERFACE - A dialysis fluid flow control system includes a pumping cassette interface including a pump area operable with a pump chamber of a disposable cassette; the cassette interface further including a volumetric reference chamber used in a volumetric control of a dialysis fluid pumped pneumatically into and out of the pump chamber of the disposable cassette; a heater connected operably to the cassette interface; and a controller connected operably to the heater so as to cause the heater to heat at least a portion of the cassette interface to a desired temperature. | 01-08-2009 |
| 20090084719 | DIALYSIS SYSTEMS HAVING AIR SEPARATION CHAMBERS WITH INTERNAL STRUCTURES TO ENHANCE AIR REMOVAL - A dialysis fluid cassette includes a rigid portion defining at least one valve chamber, the rigid portion further defining an air separation chamber, the air separation chamber when in an operating position including a first sidewall and a second sidewall, a first fluid opening, a second fluid opening, and a separation wall extending from the first sidewall to the second sidewall, the separation wall having a free edge residing within the air separation chamber, the separation wall forcing the dialysis fluid to flow from one of the fluid openings around the free edge of the separation wall to the other of the openings. | 04-02-2009 |
| 20090088675 | FLUID AND AIR HANDLING IN BLOOD AND DIALYSIS CIRCUITS - An air purging method includes: (a) detecting a low fluid level in a blood circuit indicating a high amount of air in the blood circuit; (b) stopping a blood pump; (c) closing a venous patient line; (d) opening a blood circuit air vent valve and a drain valve; and (e) running the blood pump to meter air through the air vent valve and the drain valve to a drain. | 04-02-2009 |
| 20090107902 | PERSONAL HEMODIALYSIS SYSTEM - A dialysis machine includes a dialysis instrument having a pump actuator and first and second valve actuators, and a disposable cassette operable with the dialysis instrument, the disposable cassette including a pump portion operable with the pump actuator, first and second valve chambers operable with the first and second valve actuators, the first and second valve chambers communicating fluidly with each other, at least the first valve chamber communicating fluidly with a compliance chamber, the compliance chamber negating a first backpressure due to a pneumatic closing pressure used to close the first valve chamber to help to ensure the pneumatic pressure applied to the first valve chamber will close the first valve chamber against a second backpressure from an existing closure of the second valve chamber. | 04-30-2009 |
| 20090112151 | DIALYSIS SYSTEM HAVING INTEGRATED PNEUMATIC MANIFOLD - A dialysis machine valve manifold assembly includes a plurality of pneumatic valves; a plate including a first side and a second side, the plurality of pneumatic valves mounted to the first side of the plate, the second side of the plate defining a plurality of pneumatic flow paths; and a port header mounted removably to the plate, the port header including a plurality of ports configured to connect sealingly to pneumatic tubing, the ports in fluid communication with the pneumatic valves via the pneumatic flow paths defined in the plate. | 04-30-2009 |
| 20090124963 | BALANCED FLOW DIALYSIS MACHINE - A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber. | 05-14-2009 |
| 20090198170 | MULTI-PASS DIALYSIS - A system for dialysis is disclosed. The system uses renal failure therapy fluid, such as dialysis fluid, several times before it is discarded. In a home hemodialysis application, the patient's blood is passed through the dialyzer several times, that is, multiple passes through the dialyzer, until the dialysis fluid is saturated or near saturation, with waste products from the patient's blood. In peritoneal dialysis, the dialysate is used at least twice within the patient's peritoneal cavity, i.e., multiple passes, before it is discarded. This has the effect minimizing the amount of dialysate a patient must handle and dispose of in the dialysis process. | 08-06-2009 |
| 20090281484 | PERITONEAL DIALYSIS MACHINE - A peritoneal dialysis machine including: a housing; a mechanically actuated piston head extending from a pump actuator housed by the housing, the mechanically actuated piston head positioned to extend towards and away from a fluid pumping cassette, the fluid pumping cassette coupled operably to the housing such that a flexible membrane of the fluid pumping cassette faces the piston head; a pressure sensor positioned by the housing adjacent to the mechanically actuated piston head so as to sense a pressure of a medical fluid moved by the mechanically actuated piston head within the fluid pumping cassette; and a vacuum chamber formed about the mechanically actuated piston head, the vacuum chamber holding a vacuum that sucks the flexible membrane of the fluid pumping cassette onto the mechanically actuated piston head as the mechanically actuated piston head extends away from the fluid pumping cassette. | 11-12-2009 |
| 20100010423 | DIALYSIS SYSTEM HAVING FILTERING METHOD FOR DETERMINING THERAPY PRESCRIPTIONS - A peritoneal dialysis system includes a logic implementer configured to: (i) generate a number of peritoneal dialysis therapy regimens that meet at least one therapy target input; (ii) accept a filter input; and (iii) filter the generated therapy regimens according to the filter input to refine the number of therapy regimens available for selection. | 01-14-2010 |
| 20100010424 | DIALYSIS SYSTEM HAVING REGIMEN GENERATION METHODOLOGY - A peritoneal dialysis system includes a logic implementer configured to: (i) accept at least one therapy target input; (ii) accept at least one patient transport characteristic input; (iii) accept at least one solution input; (iv) accept at least one fluid volume input; (v) accept at least one therapy time input, at least one of the inputs (ii) to (v) including an input range; and (vi) generate each therapy regimen using the inputs of (ii), (iii), (iv) and (v), including each of the possibilities within the at least one input range, that satisfy the at least one therapy target input. | 01-14-2010 |
| 20100010425 | PERITONEAL EQUILIBRATION TEST AND DIALYSIS SYSTEM USING SAME - An ultrafiltration (“UF”) evaluation method includes: (i) determining an amount of UF removed from a patient over a first dwell time; (ii) determine an amount of UF removed from the patient over a second, different dwell time; (iii) determining an amount of UF removed from the patient over a third, different dwell time; and (iv) fitting a curve to the UF removal amounts for the first, second and third dwell time. A peritoneal dialysis therapy generation method using the curve determined according to the “UF” evaluation method to generate at least one peritoneal dialysis therapy regimen. | 01-14-2010 |
| 20100010426 | DIALYSIS SYSTEM HAVING INVENTORY MANAGEMENT INCLUDING ONLINE DEXTROSE MIXING - A peritoneal dialysis system includes: a plurality of automated peritoneal dialysis (“APD”) machines; and a server computer in communication with the APD machines, the APD machines programmed to inform the server computer of how much dialysate is consumed over a first delivery period, the server computer configured to use the amounts consumed to determine dialysate delivery amounts for the plurality of APD machines for a second delivery period. | 01-14-2010 |
| 20100010427 | DIALYSIS SYSTEM HAVING TRENDING AND ALERT GENERATION - A peritoneal dialysis system includes: an automated peritoneal dialysis (“APD”) machine configured to remove ultrafiltrate (“UF”) from a patient and record how much UF has been removed; and a logic implementer configured to (i) form a first moving average UF removed trend, (ii) determine a trending range around the first moving average UF removed trend, (iii) determine at least one of an upper and lower UF removed limit from the trending range, (iv) form a second moving average UF removed trend, and (v) alert if the second moving average UF removed trend moves outside of the at least one UF removed limit. | 01-14-2010 |
| 20100010428 | DIALYSIS SYSTEM AND MACHINE HAVING THERAPY PRESCRIPTION RECALL - In one embodiment an automated peritoneal dialysis (“APD”) machine includes: at least one pump; a logic implementer storing a plurality of therapy prescriptions by which to operate the at least one pump, each therapy prescription pre-approved for a particular patient; and an input device operating with the logic implementer to allow the patient to select one of the therapy prescriptions for a particular therapy. In another embodiment, the input device operating with the logic implementer allows a doctor/clinician to select or approve one of the therapy prescriptions to be run on the APD machine. In a further embodiment, the logic implementer is programmed to select or suggest one of the therapy prescriptions to be run on the is APD machine. | 01-14-2010 |
| 20100010429 | SYSTEMS AND METHODS FOR PERFORMING PERITONEAL DIALYSIS - A regenerative peritoneal dialysis system includes a dialysis fluid loop; a filter located in the dialysis fluid loop, a first portion of the dialysis fluid sent to the filter rejected by the filter and returned upstream of the filter, a second portion of the dialysis fluid sent to the filter forming permeate, the permeate being rich in urea; and a urea removing apparatus located in the dialysis fluid loop downstream from the filter to receive the permeate and absorb urea from the permeate. | 01-14-2010 |
| 20100191180 | METHOD FOR OPTIMIZING TIDAL THERAPIES EMPLOYING ULTRAFILTRATE TRENDING - A system and method for automatically adjusting a Continuous Cycling Peritoneal Dialysis (“CCPD”) therapy to minimize the potential for excess intra-peritoneal volume. The adjustments are made at the end of the drain, just prior to the next fill. The adjustments short the next fill, if necessary, to limit the intra-peritoneal volume, add a cycle, if necessary, to use all of the available dialysis solution and will average the remaining dwell time to maximize the therapeutic benefit of the therapy in the allotted time. In another embodiment, a tidal therapy using trended patient UF data is provided. | 07-29-2010 |
| 20100191181 | DRAIN AND FILL LOGIC FOR AUTOMATED PERITONEAL DIALYSIS - A system and method for automatically adjusting a Continuous Cycling Peritoneal Dialysis (“CCPD”) therapy to minimize the potential for excess intra-peritoneal volume. The adjustments are made at the end of the drain, just prior to the next fill. The adjustments short the next fill, if necessary, to limit the intra-peritoneal volume, add a cycle, if necessary, to use all of the available dialysis solution and will average the remaining dwell time to maximize the therapeutic benefit of the therapy in the allotted time. In another embodiment, a tidal therapy using trended patient UF data is provided. | 07-29-2010 |
| 20100229366 | DIALYSIS METHOD HAVING SUPPLY CONTAINER AUTOCONNECTION - A method for connecting a plurality of solution line connectors to a plurality of supply line connectors of a dialysis system includes: translating a tip protector remover in a first direction towards the plurality of supply line connectors to remove a plurality of solution line tip protectors from the plurality of solution line connectors; locking the tip protector remover to each of a plurality of supply line tip protectors connected to the plurality of supply line connectors; translating the tip protector remover in a second direction towards the plurality of solution line connectors to remove the plurality of supply line tip protectors from the supply line connectors; translating the tip protector remover in a third direction different from the first and second directions; translating one of the plurality of solution line connectors and the plurality of supply line connectors the other of the solution line connectors and the supply line connectors to connect each of the solution line connectors to one of the supply line connectors. | 09-16-2010 |
| 20110000832 | DIALYSIS SYSTEM WITH ENHANCED FEATURES - A dialysis system includes a dialysis fluid cassette-based membrane blood pump; a dialyzer in fluid communication with the blood pump: first and second dialysis fluid cassette-based balance chambers each having (i) a fresh dialysis fluid compartment in fluid communication with the dialyzer and (ii) a spent dialysis fluid compartment; a dialysis fluid cassette-based fresh dialysis fluid membrane pump in fluid communication with the fresh dialysis fluid compartments of the first and second balance chambers; a dialysis fluid cassette-based spent dialysis fluid membrane pump in fluid communication with the dialyzer and the spent dialysis fluid compartments of the first and second balance chambers; and arterial and venous lines in fluid communication with the dialyzer for patient connection, the arterial and venous lines each including a contact used for electrically detecting a patient access disconnection. | 01-06-2011 |
| 20110004351 | DIALYSIS SYSTEM INCLUDING DOWNLOADED PRESCRIPTION ENTRY - A dialysis system includes a dialysis fluid cassette-based membrane blood pump; a dialyzer in fluid communication with the blood pump; first and second dialysis fluid cassette-based balance chambers each having (i) a fresh dialysis fluid compartment in fluid communication with the dialyzer and (ii) a spent dialysis fluid compartment; a dialysis fluid cassette-based fresh dialysis fluid membrane pump in fluid communication with the fresh dialysis fluid compartments of the first and second balance chambers; a dialysis fluid cassette-based spent dialysis fluid membrane pump in fluid communication with the dialyzer and the spent dialysis fluid compartments of the first and second balance chambers; and which is configured to receive a data transfer including a prescription entry for the system. | 01-06-2011 |
| 20110005986 | DIALYSIS SYSTEM WITH CASSETTE BASED BALANCE CHAMBERS AND VOLUMETRIC PUMPS - A dialysis system includes a fresh dialysis fluid membrane pump; a spent dialysis fluid membrane pump; a first balance chamber having a fresh dialysis fluid compartment connected fluidly to the fresh dialysis fluid membrane pump and a spent dialysis fluid compartment connected fluidly to the spent dialysis fluid membrane pump; a second balance chamber having a fresh dialysis fluid compartment connected fluidly to the fresh dialysis fluid membrane pump and a spent dialysis fluid compartment connected fluidly to the spent dialysis fluid membrane pump; and a dialysis fluid cassette, wherein at least one of the fresh dialysis fluid membrane pump, the spent dialysis fluid membrane pump, the first balance chamber and the second balance chamber includes a fluid receiving portion provided in the dialysis fluid cassette. | 01-13-2011 |
| 20110005992 | DIALYSIS SYSTEM WITH BALANCE CHAMBER PRIME AND RINSEBACK - A dialysis system includes an extracorporeal circuit including a dialyzer; a dialysis fluid circuit including a first balance chamber, a second balance chamber, a fresh dialysis fluid pump in fluid communication with first and second fresh compartments of the first and second balance chambers, respectively, the first and second fresh compartments in fluid communication with a fresh dialysate fluid inlet of the dialyzer, and a spent dialysis fluid pump in fluid communication with first and second spent compartments of the first and second balance chambers, respectively, the spent dialysis fluid pump also in fluid communication with a spent dialysis fluid outlet of the dialyzer; and wherein the system is configured to run a priming sequence that uses (i) at least one of the fresh and spent dialysis fluid pumps and the first and second balance chambers to pump dialysis fluid through the dialysis fluid circuit and (ii) at least one of the fresh and spent dialysis fluid pumps to pump dialysis fluid through the dialyzer and into the extracorporeal circuit. | 01-13-2011 |
| 20110009797 | DIALYSIS SYSTEM INCLUDING BLOOD AND DIALYSATE CASSETTE - A dialysis system including a dialysis machine including a blood pump actuator, dialysate pump actuator, a blood valve actuator and a dialysate valve actuator; and a disposable cassette operable with the dialysis machine, the disposable cassette including: (i) a housing, (ii) a dialysate pump portion of the housing configured to operate with the dialysate pump actuator, (iii) a blood valve portion of the housing configured to operate with the blood valve actuator, (iv) a dialysate valve portion of the housing configured to operate with the dialysate valve actuator, (v) a dialyzer supported by the housing, the dialyzer including a dialysate inlet and a dialysate outlet, (vi) a first dialysate connection extending externally from the housing to the dialyzer inlet, and (vii) a second dialysate connection extending externally from the housing to the dialyzer outlet. | 01-13-2011 |
| 20110009798 | RENAL THERAPY SYSTEM HAVING PUMP REVERSING FLUID CONTROL - A renal therapy system includes: a filter; an arterial blood flowpath in fluid communication with the filter; a venous blood flowpath in fluid communication with the filter; extracorporeal circuit including the filter, the arterial blood flowpath and the venous blood flowpath; a renal therapy fluid flowpath in fluid communication with the extracorporeal circuit; a plurality of renal therapy fluid valves; and first and second renal therapy fluid pumps, wherein the system is configured to operate the plurality of renal therapy fluid valves so that (i) the first renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath to the extracorporeal circuit for a number of first pump actuations and (ii) the second renal therapy fluid pump pumps renal therapy fluid through the renal therapy fluid flowpath for a number of second pump actuations. | 01-13-2011 |
| 20110105983 | HEMODIALYSIS SYSTEM INCLUDING ON-LINE DIALYSATE GENERATION - A hemodialysis system includes an on-line dialysate generator; a dialysate pump actuator configured to pump dialysate generated by the generator to a dialyzer; a conductivity sensor located adjacent to a temperature sensor upstream of the dialyzer; a blood pump actuator; an air detector; and a disposable cassette configured to carry dialysate pumped by the dialysate pump actuator, the disposable cassette including a conductivity sensor portion and a temperature sensor portion located to operate with the conductivity sensor and the temperature sensor, respectively, the disposable cassette further configured to carry blood pumped by the blood pump actuator and to provide an air detection portion located to operate with the air detector. | 05-05-2011 |
| 20110144557 | DIALYSIS SYSTEMS AND METHODS INCLUDING CASSETTE WITH FLUID HEATING AND AIR REMOVAL - A dialysis fluid system includes an instrument including a pump actuator and a fluid heater, and a dialysis fluid cassette. The dialysis fluid cassette includes a rigid portion defining a pumping section for operation with the pump actuator and a heating section for operation with the fluid heater. The heating section includes a dialysis fluid inlet, a dialysis fluid outlet, and a dialysis fluid heating area located between the fluid inlet and the fluid outlet, the heating section further includes an air separation chamber for collecting air separated from the dialysis fluid. | 06-16-2011 |
| 20110144570 | SYSTEMS AND METHODS FOR PERFORMING PERITONEAL DIALYSIS - Systems and methods for providing multiple pass continuous flow dialysis therapy are provided. The present invention includes a fluid circuit connected to a patient via a catheter thereby defining a fluid loop along which a therapy fluid including a dialysate can be continuously circulated into, through and out of a peritoneal cavity of a patient to remove a therapeutically effective amount of excess water and solutes including uremic toxins. The feed rate and discharge rate of therapy fluid into the fluid loop can be controllably regulated in proportion to the circulation rate of fluid in the fluid loop such that the therapy fluid can pass a multiple number of times along the fluid loop prior to discharge. | 06-16-2011 |
| 20110163033 | NOISE-REDUCING DIALYSIS SYSTEMS AND METHODS OF REDUCING NOISE IN DIALYSIS SYSTEMS - A dialysis system includes at least one pneumatic valve, a pneumatic pump in fluid communication with the pneumatic valve, a pneumatic line communicating with an inlet and an outlet of the pneumatic pump, a flow restrictor placed in the pneumatic line, and a logic implementer. The logic implementer is programmed to operate the pneumatic valve to either (i) communicate the pneumatic outlet with the pneumatic inlet of the pneumatic pump through the flow restrictor and the pneumatic line, or (ii) communicate the outlet of the pneumatic pump with a component of the dialysis system. | 07-07-2011 |
| 20110166507 | DIALYSIS SYSTEMS AND METHODS HAVING DISPOSABLE CASSETTE AND INTERFACE THEREFORE - A medical fluid flow control system comprises an interface including a pump actuator port and a pump seal port, a membrane gasket including a pump actuation area and a pump aperture, and a pumping cassette including a flexible sheet and defining a pump chamber, a pump portion of the flexible sheet covering the pump chamber. The pump seal port is operable with the pump aperture to seal the pump portion of the flexible sheet to the pump actuation area of the membrane gasket and the pump actuator port is configured to move the pump portion of the flexible sheet and the pump actuation area of the membrane gasket at the pump chamber of the cassette. | 07-07-2011 |