Patent application number | Description | Published |
20090186888 | NOVEL FUSED PYRROLOCARBAZOLES - The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles. | 07-23-2009 |
20100152196 | Novel Fused Pyrrolocarbazoles - The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles. | 06-17-2010 |
20100273779 | Pyridazinone Derivatives - The present invention is directed to novel pyridizinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition. | 10-28-2010 |
20100280007 | Pyridazinone Derivatives - The present invention is directed to novel pyridizinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition. | 11-04-2010 |
20100298332 | Substituted Spirocyclic Piperidine Derivatives as Histamine-3 (H3) Receptor Ligands - The present invention provides compounds of Formula (I): | 11-25-2010 |
20100311752 | Substituted pyridazine derivatives - The present invention is directed to compounds having histamine H | 12-09-2010 |
20110053920 | SUBSTITUTED BICYCLIC PYRIMIDINES - The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted heterobicyclic pyrimidines of Formula (I): | 03-03-2011 |
20110059959 | NOVEL MULTICYCLIC COMPOUNDS AND THE USE THEREOF - The present invention is directed to novel multicyclic molecules that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of PARP, VEGFR2, and MLK3 enzymes, including, for example, neurodegenerative diseases, inflammation, ischemia, and cancer. | 03-10-2011 |
20110071131 | Substituted Spirocyclic Piperidine Derivatives as Histamine-3 (H3) Receptor Ligands - The present invention provides compounds of Formula (I): | 03-24-2011 |
20110098269 | Substituted Pyridazinone Derivatives as Histamine-3 (H3) Receptor Ligands - The present invention provides compounds according to Formulas I, II, III, IV, V, VI, VII or VIII: | 04-28-2011 |
20110288075 | Pyridazinone Derivatives - The present invention is directed to novel pyridazinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition/cognitive disorders. | 11-24-2011 |
20120004231 | Substituted Pyridazine Derivatives - The present invention is directed to compounds having histamine H | 01-05-2012 |
20120004253 | Novel Fused Pyrrolocarbazoles - The present invention relates generally to selected fused pyrrolocarbazoles, including pharmaceutical compositions thereof and methods of treating diseases therewith. The present invention is also directed to intermediates and processes for making these fused pyrrolocarbazoles. | 01-05-2012 |
20120028919 | PYRROLOTRIAZINES AS ALK AND JAK2 INHIBITORS - The present invention provides a compound of formula I | 02-02-2012 |
20120238551 | Substituted Phenoxypropylcycloamine Derivatives as Histamine-3 (H3) Receptor Ligands - The present invention provides compounds of formula I: | 09-20-2012 |
20130310389 | SUBSTITUTED SPIROCYCLIC PIPERIDINE DERIVATIVES AS HISTAMINE-3 (H3) RECEPTOR LIGANDS - The present invention is directed to methods of treating disorders mediated by Histamine H | 11-21-2013 |
20140113882 | Azaquinazoline Inhibitors of Atypical Protein Kinase C - The present application provides a compound of formula (I) | 04-24-2014 |
20140142088 | PYRIDAZINONE DERIVATIVES - The present invention is directed to novel pyridazinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition. | 05-22-2014 |
20140275077 | URACIL DERIVATIVES AS AXL AND C-MET KINASE INHIBITORS - The present application provides compounds of Formula I | 09-18-2014 |
20140296212 | SUBSTITUTED PHENOXYPROPYLCYCLOAMINE DERIVATIVES AS HISTAMINE-3 (H3) RECEPTOR LIGANDS - The present invention provides compounds of formula I: | 10-02-2014 |