Patent application number | Description | Published |
20080294228 | METHOD AND DEVICE FOR CONTROLLED STIMULATION OF LYMPHATIC FLOW - A device and method for controllably augmenting the flow of lymphatic fluid through one or more lymphatic vessels. The device may utilize various means of modulating the flow of lymph, including neural, mechanical and/or chemical stimulation and could be a stand-alone device or be incorporated into any cardiac, neuromodulation and/or drug delivery device. | 11-27-2008 |
20080306561 | Multiple pulse defibrillation for subcutaneous implantable cardiac devices - Cardiac stimulation methods and systems provide for multiple pulse defibrillation, and involve sensing a fibrillation event, determining a fibrillation cycle length associated with the fibrillation event, and delivering a plurality of defibrillation pulses to treat the fibrillation event. Defibrillation pulses are delivered using a combination of subcutaneous non-intrathoracic electrodes. Delivery of each defibrillation waveform subsequent to a first defibrillation waveform is separated in time by a delay associated with the fibrillation cycle length. Delays between defibrillation waveform delivery may be associated with a percentage of the fibrillation cycle length. | 12-11-2008 |
20090054828 | Systems for transient conduction control - The invention provides a system coupled to a heart having a right atrium (RA) and an atrioventricular (AV) node, which includes an implantable gene regulatory signal delivery device configured to deliver a light to a target site in the heart to transiently control an aberrant cardiac electrical conduction, the light having characteristics suitable for regulating a transcription control element; and an implantable medical device communicatively coupled to the implantable gene regulatory signal delivery device, the implantable medical device including: an atrial fibrillation (AF) detector configured to detect AF; and a control circuit configured to initiate an emission of the light from the implantable gene regulatory signal delivery device in response to the detection of AF. Also provided are methods to transiently control aberrant AV conduction or transiently control cardiac arrhythmias, which employ expression cassettes. | 02-26-2009 |
20090054883 | Systems and devices for photoablation - The invention provides a catheter for optical ablation of tissue in a living body, the catheter including: a distal end; a proximal end; an elongate catheter body coupled between the distal end and the proximal end; a light emission device at the distal end and configured to emit an ablation light having characteristics selected to regulate an optically regulatable transcription control element operably linked to a nucleic acid sequence for a gene product, the expression of which gene product in cells directly or indirectly kills cells; and a projection control mechanism coupled to the light emission device and configured to control an effectively illuminated area where the optically regulatable transcription control element is effectively regulatable by the ablation light projected from the light emission device. Also provided is a system which includes the catheter, and methods to prevent, inhibit or treat AF which employ an expression cassette and/or one or more selected wavelengths of light. | 02-26-2009 |
20090124916 | Acoustic physiological sensor - This document describes, among other things, a body having at least one acoustically detectable property that changes in response to a change in a physiological condition, such as ischemia. The body is positioned with respect to a desired tissue region. At least one acoustic transducer is used to acoustically detect a change in physical property. In one example, the body is pH sensitive and/or ion selective. A shape or dimension of the body changes in response to pH and/or ionic concentration changes resulting from a change in an ischemia state. An indication of the physiological condition is provided to a user. | 05-14-2009 |
20090192362 | System And Method For Corroborating Transitory Changes In Wellness Status Against A Patient Population - A system and method for corroborating transitory changes in wellness status against a patient population through remote patient care is provided. A population that includes patients under remote patient care is managed. Physiometry for each patient over corresponding temporal periods is regularly obtained and contains recorded physiological measures. A wellness status for each patient is determined. The physiometry is evaluated against historical data maintained for the patient over a predetermined temporal period. Each difference in the physiometry and the historical data that exceeds a testing metric is flagged as a transitory change. Profiles of the patients in the population, which are similar, for those patients presenting corresponding transitory changes are correlated. A cumulative transitory change for the correlated patients is generated. The transitory change of each patient is corroborated against the cumulative transitory change to determine one of a match and deviation in wellness statuses. | 07-30-2009 |
20090192395 | SIGNAL COMPRESSION BASED ON CURVATURE PARAMETERS - For a sampled signal, storing characteristic points generated based on parameters corresponding to curvature of the signal. The characteristic points include a time of occurrence of a lobe in a curvature series based on the signal and a corresponding amplitude of the signal. The characteristic points provide a compressed version of the sampled signal. The signal is reconstructed by establishing a function between a chronological sequence of characteristic points. For a repetitive signal, the stored data includes a code to indicate a time of reoccurrence of a previous cycle or data corresponding to differences between a previous cycle and a current cycle. | 07-30-2009 |
20090275811 | USE OF PERIODICITY IN MEDICAL DATA ANALYSIS - A patient management system is described that includes an implantable device for collecting one or more physiological parameter values and associated timestamps indicating the time at which the value is collected. The system is then configured to determine the periodic variation, if any, of a particular physiological parameter and use that periodicity in assessing changes in the parameter values over time. | 11-05-2009 |
20100045467 | WITHIN-PATIENT ALGORITHM TO PREDICT HEART FAILURE DECOMPENSATION - This document discusses, among other things, systems and methods for predicting heart failure decompensation using within-patient diagnostics. A method comprises detecting an alert status of each of one or more sensors; calculating an alert score by combining the detected alerts; and calculating a composite alert score, the composite alert score being indicative of a physiological condition and comprising a combination of two or more alert scores. | 02-25-2010 |
20100198283 | Automatic Orientation Determination for ECG Measurements Using Multiple Electrodes - Cardiac monitoring and/or stimulation methods and systems provide monitoring, defibrillation and/or pacing therapies. A signal processor receives a plurality of composite signals associated with a plurality of sources, separates a signal using a source separation algorithm, and identifies a cardiac signal using a selected vector. The signal processor may iteratively separate signals from the plurality of composite signals until the cardiac signal is identified. The selected vector may be updated if desired or necessary. A method of signal separation involves detecting a plurality of composite signals at a plurality of locations, separating a signal using source separation, and selecting a vector that provides a cardiac signal. The separation may include a principal component analysis and/or an independent component analysis. Vectors may be selected and updated based on changes of position and/or orientation of implanted components and changes in patient parameters such as patient condition, cardiac signal-to-noise ratio, and disease progression. | 08-05-2010 |
20100250287 | OPTIMIZATION OF TIMING FOR DATA COLLECTION AND ANALYSIS IN ADVANCED PATIENT MANAGEMENT SYSTEM - Advanced patient management systems include a unit for collecting data from a device associated with a patient, and a host in communication with the unit, the host identifying a time for the device to update data on the device. The system can identify a time for the device to update data associated with the device by developing a histogram of the availability of the device for interrogation. The system can also optimize processing loads for the system by developing a histogram of the time at which the caregiver is most likely to access the system to review the collected and processed data. Methods for optimizing device data update and processing times are also included. | 09-30-2010 |
20100286737 | ARTIFICIAL CONDUCTION PATHWAYS IN TACHYARRHYTHMIA - An implantable medical device can establish one or more artificial conduction pathways during tachyarrhythmia. Withdrawal of the artificial conduction pathway may help self-terminate the tachyarrhythmia, or may pre-condition the tachyarrhythmia to be more favorable for receiving an anti-tachyarrhythmia therapy, such as anti-tachyarrhythmia pacing, defibrillation shock therapy, or cardioversion. This can help provide enhanced anti-tachyarrhythmia therapy. | 11-11-2010 |
20100305645 | TACHYARRHYTHMIA DETECTION AND DISCRIMINATION BASED ON CURVATURE PARAMETERS - Estimating a frequency of a sampled cardiac rhythm signal and classifying the rhythm. The received signal is sampled and transformed into a curvature series. A lobe in the curvature series corresponds to a characteristic point in the sampled series. Characteristic points are selected based on a time of a lobe in the curvature series and, in one embodiment, an amplitude of the signal at the time of the lobe. A frequency of the sampled series is estimated by autocorrelating a function of the series of the characteristic points. In one embodiment, the function is a time difference function. The rhythm is classified by plotting the timewise proximity of characteristic points derived from an atrial signal with characteristic points derived from a ventricular signal. Regions of the plot are associated with a particular rhythm and the grouping of the data corresponds to the classification. | 12-02-2010 |
20110009914 | CONTROLLED TITRATION OF NEUROSTIMULATION THERAPY - Described herein are methods and devices that utilize electrical neural stimulation to treat heart failure by modulating a patient's autonomic balance in a manner that inhibits sympathetic activity and/or augments parasympathetic activity. Because other therapies for treating heart failure may also affect a patient's autonomic balance, a device for delivering neural stimulation is configured to appropriately titrate such therapy in either an open-loop or closed-loop fashion. | 01-13-2011 |
20110015701 | METHOD AND APPARATUS FOR ESTABLISHING CONTEXT AMONG EVENTS AND OPTIMIZING IMPLANTED MEDICAL DEVICE PERFORMANCE - An apparatus and method for adjusting the performance of an implanted device based on data including contextual information. Contextual information, including operational and performance data concerning the implanted device as well as the patient with the implanted device, is stored by a portable electronic device. In one embodiment, the portable electronic device is adapted for battery operation and includes a personal digital assistant (PDA). The portable electronic device is adapted for use as an interface to conduct wireless communications with the implanted device. In one embodiment, the portable electronic device interfaces with a clinical programmer for use by a physician. | 01-20-2011 |
20110071848 | OPTIMIZATION OF TIMING FOR DATA COLLECTION AND ANALYSIS IN ADVANCED PATIENT MANAGEMENT SYSTEM - Advanced patient management systems include a unit for collecting data from a device associated with a patient, and a host in communication with the unit, the host identifying a time for the device to update data on the device. The system can identify a time for the device to update data associated with the device by developing a histogram of the availability of the device for interrogation. The system can also optimize processing loads for the system by developing a histogram of the time at which the caregiver is most likely to access the system to review the collected and processed data. Methods for optimizing device data update and processing times are also included. | 03-24-2011 |
20110172729 | USE OF SIGNIFICANT POINT METHODOLOGY TO PREVENT INAPPROPRIATE THERAPY - An apparatus example comprises a cardiac signal sensing circuit configured to provide a sensed cardiac signal representative of cardiac depolarization events of a subject, a sampling circuit coupled to the cardiac signal sensing circuit, a therapy circuit, and a controller communicatively coupled to the sampling circuit and the therapy circuit. The controller includes a detection module configured to detect tachyarrhythmia using the cardiac signal and a signal analysis module configured to establish significant points (SPs) of the sampled cardiac signal, estimate heart rate during the tachyarrhythmia using the SPs, and provide an indication of whether noise is present in the cardiac signal using the SPs. The controller is configured to select a therapy for delivery by the therapy circuit in response to the tachyarrhythmia detection and to modify the selected therapy according to the heart rate estimation and the noise indication. | 07-14-2011 |
20110301660 | HEART FAILURE MANAGEMENT SYSTEM - Various system embodiments comprise a stimulator adapted to deliver a stimulation signal for a heart failure therapy, a number of sensors adapted to provide at least a first measurement of a heart failure status and a second measurement of the heart failure status, and a controller. The controller is connected to the stimulator and to the number of sensors. The controller is adapted to use the first and second measurements to create a heart failure status index, and control the stimulator to modulate the signal using the index. Other aspects and embodiments are provided herein. | 12-08-2011 |
20110319726 | WITHIN-PATIENT ALGORITHM TO PREDICT HEART FAILURE DECOMPENSATION - This document discusses, among other things, systems and methods for predicting heart failure decompensation using within-patient diagnostics. A method comprises detecting an alert status of each of one or more sensors; calculating an alert score by combining the detected alerts; and calculating a composite alert score, the composite alert score being indicative of a physiological condition and comprising a combination of two or more alert scores. | 12-29-2011 |
20110319776 | CARDIAC CONTRACTION DETECTION USING INFORMATION INDICATIVE OF LEAD MOTION - Systems and methods for cardiac contraction detection using information indicative of lead motion are described. In an example, an implantable medical device can include a receiver circuit configured to be electrically coupled to conductor comprising a portion of an implantable lead and be configured to obtain information indicative of a movement of the implantable lead due at least in part to a motion of a heart. The device can include a processor circuit configured to determine whether a cardiac mechanical contraction occurred during a specified interval included in the obtained information indicative of the movement of the implantable lead. The processor circuit can be configured to determine information about the cardiac mechanical contraction using the obtained information indicative of the movement of the implantable lead. | 12-29-2011 |
20110319778 | CARDIAC FUNCTION MONITOR USING INFORMATION INDICATIVE OF LEAD MOTION - Systems and methods to monitor cardiac function using information indicative of lead motion are described. In an example, a system including an implantable medical device can include a receiver circuit configured to be electrically coupled to conductor comprising a portion of an implantable lead and be configured to obtain information indicative of a movement of the implantable lead due at least in part to a motion of a heart. The system can include a sensing circuit configured to obtain information indicative of cardiac electrical activity. The system can include a processor circuit configured to construct a template representative of a contraction of the heart, where the template can be constructed using the information indicative of the movement of the implantable lead due at least in part to the motion of the heart during the contraction, and using the information indicative of the cardiac electrical activity sensed during the contraction. | 12-29-2011 |
20110319779 | RHYTHM DISCRIMINATION USING INFORMATION INDICATIVE OF LEAD MOTION - Systems and methods for rhythm discrimination using the motion of an implantable lead are described. In an example, an implantable medical device can include a receiver circuit configured to be electrically coupled to an implantable lead and be configured to obtain information indicative of a movement of the implantable lead due at least in part to a motion of a heart. The device can include an arrhythmia detection circuit configured to determine an arrhythmia status using the information indicative of the movement of the implantable lead and an arrhythmia classification circuit configured to determine one or more of a location or a type of an arrhythmia, using the information indicative of the movement of the implantable lead, when the arrhythmia status indicates that an arrhythmia is occurring or has occurred. | 12-29-2011 |
20110319782 | CARDIAC MECHANICAL VIBRATION MONITOR USING INFORMATION INDICATIVE OF LEAD MOTION - Systems and methods to monitor cardiac mechanical vibrations using information indicative of lead motion are described. In an example, a system including an implantable medical device can include an excitation circuit configured to provide a non-tissue stimulating, non-therapeutic electrical excitation signal to a portion of an implantable lead. A receiver circuit can be configured to obtain information indicative of a mechanical vibration of the implantable lead due at least in part to one or more of an impact of at least a portion of the heart to the implantable lead, or friction contact between the implantable lead and cardiac tissue. The system can include a processor circuit configured to determine one or more of a lead mechanical status, or information indicative of valvular activity using the information indicative of the mechanical vibration of the implantable lead. | 12-29-2011 |
20120041789 | OPTIMIZATION OF TIMING FOR DATA COLLECTION AND ANALYSIS IN ADVANCED PATIENT MANAGEMENT SYSTEM - Advanced patient management systems include a unit for collecting data from a device associated with a patient, and a host in communication with the unit, the host identifying a time for the device to update data on the device. The system can identify a time for the device to update data associated with the device by developing a histogram of the availability of the device for interrogation. The system can also optimize processing loads for the system by developing a histogram of the time at which the caregiver is most likely to access the system to review the collected and processed data. Methods for optimizing device data update and processing times are also included. | 02-16-2012 |
20120197151 | USE OF PERIODICITY IN MEDICAL DATA ANALYSIS - A patient management system is described that includes an implantable device for collecting one or more physiological parameter values and associated timestamps indicating the time at which the value is collected. The system is then configured to determine the periodic variation, if any, of a particular physiological parameter and use that periodicity in assessing changes in the parameter values over time. | 08-02-2012 |
20120203092 | PATIENT HEALTH IMPROVEMENT MONITOR - Systems and methods to monitor an improvement of a subject's physiological condition using a goal improvement profile are described. In an example, a physiological condition of a subject can be compared to a goal improvement profile, where the profile includes at least one target condition indicative of an improved physiological condition detectable using a physiological sensor signal, and a target time when the subject is expected to reach the target condition, where the comparison can be used to indicate whether the subject has met the target condition by the target time. | 08-09-2012 |
20120238886 | SYSTEMS AND METHODS TO INDICATE HEART FAILURE CO-MORBIDITY - Systems and methods to indicate heart failure co-morbidity are described. In an example, one or more physiological signals can be analyzed for a specified time period to determine at least one of an indication of a heart failure event or a characteristic of heart failure co-morbidity, such as a characteristic of a non-heart failure physiological event. At least one of the different physiological signals can be compared to a specified criterion indicative of the heart failure event to provide a comparison value, where the comparison value is indicative of whether the at least one of the different physiological signals contributed towards the indication of the heart failure event. An indication of a non-heart failure physiological event can be determined using the heart failure event indication, the non-heart failure physiological event characteristic, and the comparison value indicative of whether the one or more physiological signals contributed towards the heart failure event. | 09-20-2012 |
20120245437 | Sleep State Classification - Systems and methods for sleep state classification involve detecting conditions related to sleep, including at least one condition associated with rapid eye movement (REM) sleep. Additionally, a condition modulated by the sleep-wake status of the patient may be detected. A medical system that is partially or fully implantable incorporates sensors and circuitry for detecting and processing the sleep-related signals. A sleep state processor classifies the patient's sleep state based on the sleep-related signals. Sleep state classification may be used in connection with the delivery of sleep state appropriate therapy, diagnostic testing, or patient monitoring. | 09-27-2012 |
20120245656 | CONTROLLED TITRATION OF NEUROSTIMULATION THERAPY - Described herein are methods and devices that utilize electrical neural stimulation to treat heart failure by modulating a patient's autonomic balance in a manner that inhibits sympathetic activity and/or augments parasympathetic activity. Because other therapies for treating heart failure may also affect a patient's autonomic balance, a device for delivering neural stimulation is configured to appropriately titrate such therapy in either an open-loop or closed-loop fashion. | 09-27-2012 |
20120271183 | WITHIN-PATIENT ALGORITHM TO PREDICT HEART FAILURE DECOMPENSATION - This document discusses, among other things, systems and methods for predicting heart failure decompensation using within-patient diagnostics. A method comprises detecting an alert status of each of one or more sensors; calculating an alert score by combining the detected alerts; and calculating a composite alert score, the composite alert score being indicative of a physiological condition and comprising a combination of two or more alert scores. | 10-25-2012 |
20120310099 | MONITORING OF HEART SOUNDS - A system comprises an implantable medical device (MID) including an implantableimplantabie heart sound sensor circuit configured to produce an electrical heart sound signal representative of a heart sound of a subject and a processor circuit. The processor circuit is coupled to the heart sound sensor circuit and includes a detection circuit, a heart sound feature circuit and a trending circuit. The detection circuit configured to detect a physiologic perturbation and the heart sound feature circuit is configured to identify a heart sound feature in the electrical signal. The processor circuit is configured to trigger the heart sound feature circuit in relation to a detected physiologic perturbation. The trending circuit is configured to trend the heart sound feature in relation to a recurrence of the physiologic perturbation. The processor circuit is configured to declare a change in a physiologic condition of the patient according to the trending. | 12-06-2012 |
20120323289 | METHOD AND APPARATUS FOR ESTABLISHING CONTEXT AMONG EVENTS AND OPTIMIZING IMPLANTED MEDICAL DEVICE PERFORMANCE - An apparatus and method for adjusting the performance of an implanted device based on data including contextual information. Contextual information, including operational and performance data concerning the implanted device as well as the patient with the implanted device, is stored by a portable electronic device. In one embodiment, the portable electronic device is adapted for battery operation and includes a personal digital assistant (PDA). The portable electronic device is adapted for use as an interface to conduct wireless communications with the implanted device. In one embodiment, the portable electronic device interfaces with a clinical programmer for use by a physician. | 12-20-2012 |
20130116578 | RISK STRATIFICATION BASED HEART FAILURE DETECTION ALGORITHM - A system comprises a risk analysis module and a worsening heart failure (WHF) detection module. The risk analysis module measures at least one first physiological parameter of a subject using a physiological sensor of an ambulatory medical device, and determines a heart failure (HF) risk score for the subject according to the at least one measured first physiological parameter. The HF risk score indicates susceptibility of the subject to experiencing a HF event. The WHF detection module measures at least one second physiological parameter of the subject using the same or different physiological sensor, and generates an indication of prediction that the subject will experience a WHF event when the at least one second physiological parameter satisfies a WHF detection algorithm. The risk analysis module adjusts generation of the indication by the WHF detection algorithm according to the determined HF risk score. | 05-09-2013 |
20130123873 | HEART FAILURE MANAGEMENT - Various system embodiments comprise a stimulator adapted to deliver a stimulation signal for a heart failure therapy, a number of sensors adapted to provide at least a first measurement of a heart failure status and a second measurement of the heart failure status, and a controller. The controller is connected to the stimulator and to the number of sensors. The controller is adapted to use the first and second measurements to create a heart failure status index, and control the stimulator to modulate the signal using the index. Other aspects and embodiments are provided herein. | 05-16-2013 |
20130245466 | WITHIN-PATIENT ALGORITHM TO PREDICT HEART FAILURE DECOMPENSATION - This document discusses, among other things, systems and methods for predicting heart failure decompensation using within-patient diagnostics. A method comprises detecting an alert status of each of one or more sensors; calculating an alert score by combining the detected alerts; and calculating a composite alert score, the composite alert score being indicative of a physiological condition and comprising a combination of two or more alert scores. | 09-19-2013 |
20140031643 | HEART FAILURE PATIENTS STRATIFICATION - A system, apparatus and method are provided to quantify a risk of worsening heart failure for subject using at least one physiological sensor circuit such as, for example, a heart sound sensor, a respiration sensor, a cardiac activity sensor, or other sensor circuit. A central tendency measurement of the at least one physiological sensor can be used to quantify the risk of worsening heart failure of the subject. | 01-30-2014 |
20140046200 | MONITORING OF HEART SOUNDS - This document discusses, among other things, a system comprising an implantable medical device (IMD) including an implantable heart sound sensor circuit configured to produce an electrical heart sound signal representative of a heart sound of a subject and a processor circuit. The processor circuit is coupled to the heart sound sensor circuit and includes a detection circuit, a heart sound feature circuit and a trending circuit. The detection circuit configured to detect a physiologic perturbation and the heart sound feature circuit is configured to identify a heart sound feature in the electrical signal. The processor circuit is configured to trigger the heart sound feature circuit in relation to a detected physiologic perturbation. The trending circuit is configured to trend the heart sound feature in relation to a recurrence of the physiologic perturbation. The processor circuit is configured to declare a change in a physiologic condition of the patient according to the trending. | 02-13-2014 |
20140114370 | HEART FAILURE MANAGEMENT - Various system embodiments comprise a stimulator adapted to deliver a stimulation signal for a heart failure therapy, a number of sensors adapted to provide at least a first measurement of a heart failure status and a second measurement of the heart failure status, and a controller. The controller is connected to the stimulator and to the number of sensors. The controller is adapted to use the first and second measurements to create a heart failure status index, and control the stimulator to modulate the signal using the index. Other aspects and embodiments are provided herein. | 04-24-2014 |
20140236026 | METHOD AND APPARATUS FOR MULTI-STATE HEART FAILURE DECOMPENSATION DETECTION - Devices and methods for detecting events indicative of heart failure (HF) decompensation status are described. An ambulatory medical device can determine the present physiologic state as being either a drift state or a stable state, and applies an algorithm to detect HF decompensation event according to the physiologic state. In some embodiments, the ambulatory medical device uses the present physiologic state to estimate one ore more expected future signal characteristics, and to detect HF decompensation event using the one or more expected futures signal characteristics. | 08-21-2014 |
20140243929 | CONTROLLED TITRATION OF NEUROSTIMULATION THERAPY - Described herein are methods and devices that utilize electrical neural stimulation to treat heart failure by modulating a patient's autonomic balance in a manner that inhibits sympathetic activity and/or augments parasympathetic activity. Because other therapies for treating heart failure may also affect a patient's autonomic balance, a device for delivering neural stimulation is configured to appropriately titrate such therapy in either an open-loop or closed-loop fashion. | 08-28-2014 |
20140343438 | METHODS AND APPARATUS FOR DETECTING HEART FAILURE EVENT USING PATIENT CHRONIC CONDITIONS - Devices and methods for detecting physiological target event such as events indicative of HF decompensation status are described. A medical device is configured to receive at least a first and a second chronic condition indictors of a patient, receive one or more physiologic signals from the patient, and generate a plurality of signal metrics when the first and the second chronic condition indicators meet their respective criterion. The medical device can detect the target event or condition using one or more patient-specific signal metrics selected from a group including both the first and the second set of the signal metrics. The medical device and the methods can be configured to detect an event indicative of HF decompensation. | 11-20-2014 |
20140343439 | METHODS AND APPARATUS FOR STRATIFYING RISK OF HEART FAILURE DECOMPENSATION - Devices and methods for identifying patient at elevated risk of developing future heart failure (HF) events, such as events indicative of HF decompensation status, are described. The devices and methods can stratify the risk using sensor signals or signal metrics selected in accordance with patient chronic conditions. A medical device can receive a patient status input including at least a first and a second chronic condition indicators, sense one or more physiologic signals from the patient, and generate a plurality of signal metrics from the physiologic signals when the first chronic condition indicator and the second chronic condition indicator meets respective criterion. One or more patient-specific signal metrics can be selected from a group including the signal metrics selected for both the first and the second chronic conditions. A risk stratification algorithm can use the selected one or more patient-specific signal metrics to compute a composite risk index indicative of the probability of the patient later developing an event indicative of worsening of HF. | 11-20-2014 |
20150025404 | METHODOLOGY FOR AUTOMATED SIGNAL MORPHOLOGY ANALYSIS IN IMPLANTABLE ELECTROTHERAPY AND DIAGNOSTIC SYSTEMS - Systems and related methods for analyzing data sensed from a device implanted in a patient, such as a cardiac pacing system. The system detects and evaluates electric signals within the patient that share a common event marker. By using algorithms and graphical presentation of the collected signals having common event markers, deviations in signals over time can be identified and evaluated in consideration of taking further action related to the patient and the implanted device. The system can also be used in conjunction with an advanced patient management system that includes a programmer or repeater capable of gathering information from the implanted device and transmitting the data to a host via a communications network for evaluation at a remote location. | 01-22-2015 |
20150088026 | METHODS AND APPARATUS FOR DETECTING HEART FAILURE EVENT USING RANK OF THORACIC IMPEDANCE - Devices and methods for detecting physiological target event such as events indicative of HF decompensation status are described. An ambulatory medical device (AMD) can measure bio-impedance, such as thoracic impedance, from a patient. The AMD can receive a specified threshold within a range or a distribution of impedance measurement, or a specified percentile such as less than 50 | 03-26-2015 |