Patent application number | Description | Published |
20090007906 | Methods and Formulations for the Efficient Delivery of Drugs by Nebulizer - Formulations, methods and devices for producing formulations and methods for nebulizer delivery of formulations of water-insoluble drugs and drugs requiring storage in aqueous or other water-miscible pharmaceutically unacceptable vehicles for stability are provided. Also provided are methods for minimizing wastage of drugs administered by nebulizer, and for the achievement of quantitative dosing with diluent from a mass marketed formulations, which because of the mass market is much less costly per dose than formulations manufactured specifically for much lower volume medical use. | 01-08-2009 |
20090270752 | Devices for Measuring Inspiratory Airflow - New applications of unidirectional airflow sensing in devices which measure inspiratory airflow and bidirectional airflow are provided. Such devices can be used for administration of a medication via inhalation, in spirometers and in devices which measure and monitor respiratory ventilation. | 10-29-2009 |
20110092840 | INTELLIGENT AIR FLOW SENSORS - A single sensor capable of detecting both airflow in spirometry and the full range of sound frequencies needed to track clinically relevant breath sounds is provided. The airflow sensor includes a movable flap with one or more integrated strain gauges for measuring displacement and vibration. The airflow sensor is inherently bidirectional. The sensor is an elastic flap airflow sensor that is capable of detecting data needed for both spirometry and auscultation measurements. The sensor is sterilizable and designed for the measurement of human respiratory airflow. The sterilizable sensor is also suitable for non-medical fluid flow metering applications. Additional devices such as sensors for the ambient level of various chemicals, sensors for temperature, sensors for humidity and microphones, may be affixed to the flap. When the strain gauge is placed in a conventional Wheatstone bridge configuration, the sensor can provide the airflow measurements needed for medical spirometry. | 04-21-2011 |
20110153620 | Method and apparatus for improving the transcription accuracy of speech recognition software - A virtual vocabulary database is provided for use with a with a particular user database as part of a speech recognition system. Vocabulary elements within the virtual database are imported from the user database and are tagged to include numerical data corresponding to the historical use of the vocabulary element within the user database. For each speech input, potential vocabulary element matches from the speech recognition system are provided to the virtual database software which creates virtual sub-vocabularies from the criteria according to predefined criteria templates. The software then applies vocabulary element weighting adjustments according to the virtual sub-vocabulary weightings and applies the adjustment to the default weighting provided by the speech recognition system. The modified weightings are returned with the associated vocabulary elements to the speech engine for selection of an appropriate match to the input speech. | 06-23-2011 |
20120035449 | Apparatus method and for intelligent electronic medical devices - An enhanced electronic medical device is provided that combines some of the enhanced electronic features found in other electronic medical devices with software for executing a stochastic process control and evaluating the digital respiratory and other physiological data collected by the electronic medical device. The programmed stochastic process control is capable of selecting and calculating any one of a number of pulmonary function and other physiological parameters including at least one statistical process control variable to determine a pulmonary or other physiological threshold. Information systems linking doctor's offices and patient's electronic medical devices are further provided to transmit warning data in cases where the pulmonary or other physiological threshold is exceeded. | 02-09-2012 |
20120277615 | METHOD AND APPARATUS FOR INTELLIGENT FLOW SENSORS - A single sensor capable of detecting both airflow in spirometry and the full range of sound frequencies needed to track clinically relevant breath sounds is provided. The airflow sensor includes a movable flap with one or more integrated strain gauges for measuring displacement and vibration. The airflow sensor is inherently bidirectional. The sensor is an elastic flap airflow sensor that is capable of detecting data needed for both spirometry and auscultation measurements. The sensor is sterilizable and designed for the measurement of human respiratory airflow. The sterilizable sensor is also suitable for non-medical fluid flow metering applications. Additional devices such as sensors for the ambient level of various chemicals, sensors for temperature, sensors for humidity and microphones, may be affixed to the flap. When the strain gauge is placed in a conventional Wheatstone bridge configuration, the sensor can provide the airflow measurements needed for medical spirometry. | 11-01-2012 |
20130245980 | METHOD AND APPARATUS FOR INTELLIGENT AIRFLOW SENSORS - A sensor capable of detecting both airflow in spirometry and a full range of sound frequencies is provided. The airflow sensor includes a movable flap with one or more integrated strain gauges for measuring displacement and vibration. The sensor may be a bidirectional elastic flap airflow sensor that is capable of providing data needed for both spirometry and auscultation measurements. The sensor is provided in connection with a software module that analyzes sensor output waveforms and provides for correction functions that correct for certain non-linear response functions of the flap. The correction functions are also suitable for non-medical fluid flow metering applications. Additional devices may also be affixed to the flap, such as sensors for the ambient level of various chemicals, sensors for temperature, sensors for humidity and microphones. | 09-19-2013 |
20150140040 | METHODS OF DEPOSITING PARTICLES OF A SUBSTANCE IN A TISSUE - Provided herein are methods of populating a target tissue of interest of a subject with particles of a substance of interest by precipitation. Example methods include administering a solution to a subject, the solution including the substance of interest and a pharmaceutically acceptable solvent. The substance of interest must be soluble in a pharmaceutically acceptable, water-miscible solvent but insoluble in tissue fluids of the target tissue of interest; and the pharmaceutically acceptable solvent must be freely miscible with the tissue fluids of the target tissue of interest. According to example embodiments, the solution is administered in a volume of the pharmaceutically acceptable solvent that will be diluted by tissue fluids in the target tissue of interest following administration at a rate that will result in precipitation of an effective amount of particles of the substance of interest in a range of sizes that will accomplish a purpose for which the substance is administered. Examples of the present methods include administering the solution to tissue of an animal, such that the substance of interest in the solution precipitates and provides an effective amount of insoluble particles of the substance of interest to the tissue. Also provided are kits that include the solution or components thereof; and methods of making such solutions. | 05-21-2015 |