Rick Wagner, Cambridge US
Rick Wagner, Cambridge, MA US
Patent application number | Description | Published |
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20080299673 | Method for Employing a Biosensor to Detect Small Molecules ("Fragments") that Bind Directly to Immobilized Protein Targets - The invention provides method of detecting interactions of small molecules with target molecules. | 12-04-2008 |
20090130703 | Methods of Detection of Changes in Cells - Methods are provided to detect changes in cells without the use of detection labels. | 05-21-2009 |
20090131360 | Tripartite RNAi constructs - The present invention provides compositions and methods for inhibiting expression of a target gene in a cell. The process comprises introduction of double-stranded tripartite RNAi constructs into the cells and reducing the expression of the corresponding messenger RNA in the cells. The constructs, which may be packaged in or delivered as sequestered RNAi constructs, differ from the canonical siRNA in that they comprise a tripartite structure which follows the general formula of having (1) an RNAi core (either native or abbreviated), (2) one or more terminal moieties attached to the RNAi core and optionally (3) a linker between the RNAi core and the terminal moiety. Once packaged into sequestration vehicles, the constructs are activated for gene regulation by the application of certain forms of energy | 05-21-2009 |
20090137422 | Methods for Identifying Modulators of Ion Channels - The invention provides methods for identifying modulators of ion channels without the use of recombinant cell lines over-expressing the ion channel proteins or the use of detection labels. | 05-28-2009 |
20090305304 | High Resolution Label Free Analysis of Cellular Properties - The invention provides methods of detecting a change in cell growth patterns. | 12-10-2009 |
20100291575 | Detection of Changes in Cell Populations and Mixed Cell Populations - The invention provides methods of label-free detection of changes in cell populations and mixed cell populations. | 11-18-2010 |
20110237535 | Use of Induced Pluripotent Cells and other Cells for Screening Compound Libraries - The invention provides methods for screening test compounds or toxins for effects on cells. The invention also provides methods for determining frequency, amplitude and kinetic profiles of cells. | 09-29-2011 |
20120040866 | High Resolution Label Free Analysis of Cellular Properties - The invention provides methods of detecting a change in cell growth patterns. | 02-16-2012 |