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Richard Wyatt
Richard Wyatt, West Chester, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100219994 | SYSTEMS AND METHODS FOR OPTIMIZING BIT UTILIZATION IN DATA ENCODING - In one of many possible embodiments, a system for optimizing bit utilization in data encoding is provided. The exemplary system includes a data processing subsystem configured to identify a total number of unique characters within a set of data, which number represents an original base of representation of the set of data. The data processing subsystem is further configured to convert the set of data to a base of representation that is higher than the original base of representation and then encode the base-converted data with a fixed-length encoding scheme. | 09-02-2010 |
| 20110234432 | SYSTEMS AND METHODS FOR OPTIMIZING BIT UTILIZATION IN DATA ENCODING - In one of many possible embodiments, a system for optimizing bit utilization in data encoding is provided. The exemplary system includes a data processing subsystem configured to identify a total number of unique characters within a set of data, which number represents an original base of representation of the set of data. The data processing subsystem is further configured to convert the set of data to a base of representation that is higher than the original base of representation and then encode the base-converted data with a fixed-length encoding scheme. | 09-29-2011 |
Richard Wyatt, Ipswich GB
| Patent application number | Description | Published |
|---|---|---|
| 20090016741 | OPTICAL COMMUNICATION - The present invention relates to a method of optical communication, in particular optical communication involving spectral filtering in a passive optical network. The method includes the steps of: (i) performing a first spectral filtering function on a source signal having a spectral width so as to generate a plurality of feeder signals that are spectrally spaced apart from one another; (ii) performing a respective noise reduction function on the feeder signals; (iii) combining the feeder signals over a common waveguide of the optical link; (iv) receiving the feeder signals carried over the optical link and modulating the received feeder signals so as to impose data thereon; and, (v) returning the modulated feeder signals over the optical link so as to communicate the imposed data. Because noise is reduced centrally, a simpler passive optical network can be achieved. | 01-15-2009 |
| 20100142962 | MULTIWAVELENGTH TRANSMITTER - A multiwavelength transmitter comprises several laser sources ( | 06-10-2010 |
Richard Wyatt, Rockville, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20080267989 | Hiv Gp-41-Membrane Proximal Region Arrayed On Hepatitis B Surface Antigen Particles as Novel Antigens - Recombinant HBsAg-gp120 has been used to present approximately amino acids 1-500 gp120. However, this presentation of gp120 in this form has not successfully been used to produce neutralizing antibodies. The use of the immunogenic Hepatitis B surface antigen (HBsAg) particulate platform to array specific epitopes from the conserved, neutralization-sensitive membrane proximal region (MPR) of HIV-1, and the use of these monomeric fusion proteins, polymeric forms of these fusion proteins, and nucleic acids encoding these fusion proteins to induce an immune response to HIV-1 are disclosed. | 10-30-2008 |
| 20090110690 | Hiv Gp120 Crystal Structure and Its Use to Identify Immunogens - The present disclosure relates to stabilized forms of the HIV gp120 envelope protein in complex with the broadly neutralizing CD4-binding site antibody b12, to crystalline forms of the stabilized forms of the HIV gp120 envelope protein in complex with the broadly neutralizing CD4-binding site antibody b12, and to the high resolution structure obtained from these crystals by X-ray diffraction methods. Methods for identifying immunogenic polypeptides based on these structures are also disclosed. | 04-30-2009 |
| 20090191235 | CONFORMATIONALLY STABILIZED HIV ENVELOPE IMMUNOGENS AND TRIGGERING HIV-1 ENVELOPE TO REVEAL CRYPTIC V3-LOOP EPITOPES - Stabilized forms of gp120 polypeptide, nucleic acids encoding these stabilized forms, vectors comprising these nucleic acids, and methods of using these polypeptides, nucleic acids, vectors and host cells are disclosed. Crystal structures and computer systems including atomic coordinates for stabilized forms of gp120, and gp120 with an extended V3 loop, and methods of using these structures and computer systems are also disclosed. | 07-30-2009 |
| 20090220536 | HIV vaccine immunogens and immunization strategies to elicit broadly-neutralizing anti-HIV-1 antibodies against the membrane proximal domain of HIV GP41 - This invention relates to novel peptide immunogens that generate an immune response in mammals against HIV gp41, to pharmaceutical compositions that comprise such immunogens, and to methods of treating Immunodeficiency disease, especially HIV infection and AIDS, that employ such pharmaceutical compositions. | 09-03-2009 |
| 20100068217 | EPITOPE-TRANSPLANT SCAFFOLDS AND THEIR USE - Computational protocols for the design of epitope-protein scaffolds which elicit selected neutralizing antibodies are disclosed, and related compositions and uses. | 03-18-2010 |
Richard Wyatt, La Jolla, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110244477 | ANTIBODY-SECRETING CELL ASSAY - An improved assay is described where a surface is provided with immobilized anti-Ig antibodies rather than antigen and where specific antibody-secreting cells (ASC) are detected using soluble antigen probes containing one of several possible labels. The method gives improved sensitivity with less background and is also more representative because antigen binding does not employ immobilized antigen. The assay is particularly effective for measuring antibody secreting cells against HIV, for determining whether an infection is acute as opposed to old or latent, for mapping epitopes and for measuring for ASCs against different antigens in the same reaction. | 10-06-2011 |
Richard Wyatt, Woodbridge GB
| Patent application number | Description | Published |
|---|---|---|
| 20120008650 | HYBRID INTEGRATED TUNEABLE LASER - A hybrid integrated tuneable optical laser device, suitable for tuning to different wavelengths via a piezo micromotor ( | 01-12-2012 |