Patent application number | Description | Published |
20100191493 | Spectrum Searching Method That Uses Non-Chemical Qualities of the Measurement - Methods and systems for determining information about a sample are disclosed. The methods can include measuring spectral information for the sample and determining a quantity related to a signal-to-noise ratio for the spectral information, repeating the measuring and determining until a value of the quantity is beyond a threshold value, and comparing the spectral information to reference information to determine the information about the sample. | 07-29-2010 |
20100198524 | Spectrum Searching Method That Uses Non-Chemical Qualities of the Measurement - Methods and systems for determining information about a sample are disclosed. The methods can include measuring spectral information for the sample and determining a quantity related to a signal-to-noise ratio for the spectral information, repeating the measuring and determining until a value of the quantity is beyond a threshold value, and comparing the spectral information to reference information to determine the information about the sample. | 08-05-2010 |
20100290042 | Use of Free-space Coupling Between Laser Assembly, Optical Probe Head Assembly, Spectrometer Assembly and/or Other Optical Elements for Portable Optical Applications Such as Raman Instruments - An apparatus includes: a handheld Raman analyzer that can include: a common platform; a laser assembly mounted on a laser platform, the laser platform supported on the common platform by a first material and a second thermally conductive material wherein the first material is softer than the second material; an optical probe head assembly disposed on the common platform, the optical probe head assembly spaced apart from the laser assembly; a spectrometer assembly disposed on the common platform, the spectrometer assembly spaced apart from the optical probe head assembly; and an analysis apparatus configured to identify a specimen based on a Raman signature received from the spectrometer. The laser assembly can be optically coupled to the optical probe head assembly by at least a first free-space coupling region and the optical probe head assembly optically coupled to the spectrometer assembly by at least a second free-space coupling region. | 11-18-2010 |
20100315629 | Optical Scanning - Disclosed are apparatus, kits, methods, and systems that include a radiation source configured to direct radiation to a sample; a detector configured to measure radiation from the sample; an electronic processor configured to determine infotmation about the sample based on the measured radiation; a housing enclosing the source, the detector, and the electronic processor, the housing having a hand-held form factor; an arm configured to maintain a separation between the sample and the housing, the arm including a first end configured to connect to the housing and a second end configured to contact the sample; and a layer positioned on the second end of the arm, the layer being configured to contact the sample and to transmit at least a portion of the radiation from the sample to the detector. | 12-16-2010 |
20110257918 | SPECTRUM SEARCHING METHOD THAT USES NON-CHEMICAL QUALITIES OF THE MEASUREMENT - Methods and systems for determining information about a sample are disclosed. The methods can include measuring spectral information for a sample and determining a quantity related to a signal-to-noise ratio for the spectral information, repeating the measuring and determining until a value of the quantity is beyond a threshold value, and comparing the spectral information to reference information to determine information about the sample. | 10-20-2011 |
20140374601 | Method and Apparatus for the Application of Force to a Sample for Detection Using an Electromechanical Means - The embodiments of the present invention are directed to applying intimate contact pressures to samples while undergoing ATR infrared interrogation. As a general mode of operation, after a solid sample is placed on the ATR element, a force actuator moves an anvil arm to apply a contact force to the sample against the ATR. Thereafter, when the scan is over, the user can see the result of the one or more scans. The force actuator may be a motor or a solenoid or other type of force actuator. The applied contact force may be a fixed force or may be a user-selectable force or may be automatically controlled through feedback from the spectrometer based on the spectroscopic signature of the sample material. | 12-25-2014 |
20150036135 | OPTICAL SCANNING - Disclosed are apparatus, kits, methods, and systems that include a radiation source configured to direct radiation to a sample; a detector configured to measure radiation from the sample; an electronic processor configured to determine information about the sample based on the measured radiation; a housing enclosing the source, the detector, and the electronic processor, the housing having a hand-held form factor; an arm configured to maintain a separation between the sample and the housing, the arm including a first end configured to connect to the housing and a second end configured to contact the sample; and a layer positioned on the second end of the arm, the layer being configured to contact the sample and to transmit at least a portion of the radiation from the sample to the detector. | 02-05-2015 |
Patent application number | Description | Published |
20080224895 | Adaptive range vehicle locating unit, vehicle tracking unit and vehicle recovery system including same - An adaptive range vehicle recovery system including an adaptive range vehicle locating unit including a narrowband baseband generator for generating a narrowband signal, a wideband baseband generator for generating a wideband signal, a timing control circuit responsive to an activation signal to transmit, alternately, said narrowband signal at a first rate, and said wideband signal at a second rate and responsive to a track signal to transmit one of said wideband and narrowband signals at a third, different, rate; and also to an adaptive range vehicle recovery system including an adaptive range vehicle track unit including a data decoder including, a wideband decoder for detecting data from a wideband baseband signal, a narrowband decoder for detecting data from a narrowband baseband signal, a bandwidth detector responsive to a received signal to distinguish narrowband and wideband signals and an input switching circuit responsive to said bandwidth detector for directing the wideband signal to the wideband decoder and the narrowband signal to the narrowband decoder. | 09-18-2008 |
20090305640 | Vehicle locating unit with improved power management method - A method of checking messages from a network of communication sources includes initially testing the signal strength of a plurality of communication sources, storing the identity of the communication sources with the two strongest signals, and alternatively entering a sleep mode and a wake-up mode, the wake-up mode synchronized to the communication source with the strongest signal. The method further includes testing the signal strength of one additional communication source, switching synchronization to the additional communication source if said source presents a signal stronger than the signal of a stored communication source with the strongest signal, and replacing the identity of any stored communication source if an additional communication sources tested in sequence presents a signal stronger than the signal of said stored communication source. | 12-10-2009 |
20110095915 | Power management system and method for vehicle locating unit - Improved power management for a vehicle locating unit is achieved by receiving a transmission from a communication source, each transmission including at least one message frame having a data field and at least one auxiliary field; entering a wake mode upon indexing the assigned message frame of the receiver in the transmission; matching the pattern of bits of at least one auxiliary field of the indexed frame with one or more stored patterns of bits expected for that auxiliary field; and returning to the sleep mode as soon as a mismatch is determined or processing the message if no mismatch occurs. | 04-28-2011 |
20110098015 | Synchronization system and method for achieving low power battery operation of a vehicle locating unit in a stolen vehicle recovery system which receives periodic transmissions - Synchronization for achieving low power battery operation of a vehicle locating unit in a stolen vehicle recovery system whose radio receiver receives periodic transmissions, includes receiving periodic transmissions; turning on a radio receiver for a limited time to detect an expected message; if an expected message is not found, turning off the receiver and turning it on again after a time asynchronous with the transmission period; and after finding an expected message, waiting for the period of the transmissions less the length of an expected message and then looking for a synchronization symbol in the expected message and synchronizing subsequent actuation of the receiver using that synchronization symbol. | 04-28-2011 |
Patent application number | Description | Published |
20120141456 | Use of DR6 and p75 Antagonists to Promote Survival of Cells of the Nervous System - The present invention relates to Death Receptor-6 (DR6) proteins which are members of the tumor necrosis factor (TNF) receptor family, and have now been shown to be important for regulating apoptosis in cells of the nervous system. In addition, it has been discovered that p75 is a ligand for DR6. As a result, this invention relates to methods for inhibiting the interaction of DR6 and p75 using DR6 and/or p75 antagonists. In addition, the methods described herein include methods of promoting survival of cells of the nervous system using DR6 antagonists, optionally in combination with p75 antagonists, and methods of treating neurodegenerative conditions by the administration of a DR6 antagonists, optionally in combination with a p75 antagonist. | 06-07-2012 |
20130040360 | Crystal Structure of the Pro Form of a Matrix Metalloproteinase and an Allosteric Processing Inhibitor - The present invention includes a crystal comprising a complex of the pro form of a matrix metalloprotease (proMMP) and a small-molecule allosteric processing inhibitor that inhibits that activation of the proMMP, methods for identifying small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP, and methods of treatment using small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP. The present invention relates to the crystal structure of a complex of proMMP9 bound to a small-molecule allosteric processing inhibitor that inhibits activation of proMMP9. The invention further relates to the use of the methods and the crystal and related structural information for designing, selecting and/or optimizing small-molecule allosteric processing inhibitors that inhibit activation of proMMP9 and proMMP9 homologues. The present invention also relates to the use of small-molecule allosteric processing inhibitors for the treatment of diseases mediated by inappropriate matrix metalloproteinase (MMP) activity. | 02-14-2013 |
20130040994 | Methods of Treatment Using Allosteric Processing Inhibitors for Matrix Metalloproteinases - The present invention includes a crystal comprising a complex of the pro form of a matrix metalloprotease (proMMP) and a small-molecule allosteric processing inhibitor that inhibits that activation of the proMMP, methods for identifying small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP, and methods of treatment using small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP. The present invention relates to the crystal structure of a complex of proMMP9 bound to a small-molecule allosteric processing inhibitor that inhibits activation of proMMP9. The invention further relates to the use of the methods and the crystal and related structural information for designing, selecting and/or optimizing small-molecule allosteric processing inhibitors that inhibit activation of proMMP9 and proMMP9 homologues. The present invention also relates to the use of small-molecule allosteric processing inhibitors for the treatment of diseases mediated by inappropriate matrix metalloproteinase (MMP) activity. | 02-14-2013 |
20130166268 | Crystal Structure of the Pro Form of a Matrix Metalloproteinase and an Allosteric Processing Inhibitor - The present invention includes a crystal comprising a complex of the pro form of a matrix metalloprotease (proMMP) and a small-molecule allosteric processing inhibitor that inhibits that activation of the proMMP, methods for identifying small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP, and methods of treatment using small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP. The present invention relates to the crystal structure of a complex of proMMP9 bound to a small-molecule allosteric processing inhibitor that inhibits activation of proMMP9. The invention further relates to the use of the methods and the crystal and related structural information for designing, selecting and/or optimizing small-molecule allosteric processing inhibitors that inhibit activation of proMMP9 and proMMP9 homologues. The present invention also relates to the use of small-molecule allosteric processing inhibitors for the treatment of diseases mediated by inappropriate matrix metalloproteinase (MMP) activity. | 06-27-2013 |
20140010826 | Use of DR6 and p75 Antagonists to Promote Survival of Cells of the Nervous System - The present invention relates to Death Receptor-6 (DR6) proteins which are members of the tumor necrosis factor (TNF) receptor family, and have now been shown to be important for regulating apoptosis in cells of the nervous system. In addition, it has been discovered that p75 is a ligand for DR6. As a result, this invention relates to methods for inhibiting the interaction of DR6 and p75 using DR6 and/or p75 antagonists. In addition, the methods described herein include methods of promoting survival of cells of the nervous system using DR6 antagonists, optionally in combination with p75 antagonists, and methods of treating neurodegenerative conditions by the administration of a DR6 antagonists, optionally in combination with a p75 antagonist. | 01-09-2014 |
20150203585 | Use of DR6 and p75 Antagonists to Promote Survival of Cells of the Nervous System - The present invention relates to Death Receptor-6 (DR6) proteins which are members of the tumor necrosis factor (TNF) receptor family, and have now been shown to be important for regulating apoptosis in cells of the nervous system. In addition, it has been discovered that p75 is a ligand for DR6. As a result, this invention relates to methods for inhibiting the interaction of DR6 and p75 using DR6 and/or p75 antagonists. In addition, the methods described herein include methods of promoting survival of cells of the nervous system using DR6 antagonists, optionally in combination with p75 antagonists, and methods of treating neurodegenerative conditions by the administration of a DR6 antagonists, optionally in combination with a p75 antagonist. | 07-23-2015 |
Patent application number | Description | Published |
20080203147 | Internet-based shipping, tracking, and delivery network supporting a plurality of mobile digital image capture and processing (MICAP) systems - An Internet-based shipping, tracking, and delivery network including a data collection and processing center operably connected to the infrastructure of the Internet, and including a RDBMS for storing and managing shipping information, and a plurality of pickup/delivery vehicles. Each pickup/delivery vehicle is equipped with a mobile digital image capture and processing (MICAP) system for (i) capturing and processing digital images of shipping documents, bearing embedded bar codes, at the point of pickup, (ii) automatically decoding embedded bar codes in said shipping documents, and performing optical character recognition (OCR) on text presented therein, (iii) formatting captured digital images of the shipping labels with such decoded/recognized information, and (iv) transmitting the formatted digital images to said data collection and processing center, for automatic recognition processing and population of the RDBMS maintained by said network. | 08-28-2008 |
20080203166 | Web-enabled mobile image capturing and processing (MICAP) cell-phone - A Web-enabled mobile image capturing and processing (MICAP) cell-phone for use on a Web-based shipping, tracking and delivery network. The cell-phone include a hand-supportable housing, and a digital image capture and processing engine for capturing and processing digital images of shipping documents at a point of shipment pickup. An imaging-based bar code reading engine is integrated with the housing for recognizing 1D and/or 2D bar-coded labels in captured digital images. A display panel displays digital images. An RF transceiver circuit, with an RF antenna, supports wireless data communication protocols. A microprocessor and memory aboard the cellphone provides a computing platform supporting an operating system (OS) and one or more application programs, including a Web browser program, and a client application program. At least the application program supports the automatically reading of bar-coded shipment tracking numbers graphically represented in the captured digital images, and automatically generates digital image files (i) having headers that are encoded with machine-recognized shipment tracking numbers, and (ii) which are named or titled using the machine-recognized shipment tracking numbers. | 08-28-2008 |
20080210749 | Internet-based shipping, tracking, and delivering network supporting a plurality of mobile digital image capture and processing instruments deployed on a plurality of pickup and delivery couriers - An Internet-based shipping, tracking, and delivery network supporting a plurality of mobile digital image capture and processing instruments deployed on a plurality of pickup and delivery couriers. Each mobile digital image capture and processing instrument can upload digital images of shipping documents to one or more application servers and/or human-operated data-keying workstations supported on the network for machine and/or human-assisted recognition-processing, and acquisition of shipping information contained in the digital images and the entry of shipping information into an RDBMS maintained on the network for the purpose of supporting its shipping, tracking, and delivery operations. | 09-04-2008 |
20080210750 | Internet-based shipping, tracking, and delivery network supporting a plurality of digital image capture and processing instruments deployed aboard a plurality of pickup/delivery vehicles - The Internet-based shipping, tracking, and delivery network supporting a plurality of digital image capture and processing instruments deployed aboard a plurality of pickup/delivery vehicles, wherein each digital image capture and processing instrument can upload digital images of shipping documents wirelessly to a cellular telephone which, in turn, transmits the digital images to one or more application servers and/or human-operated data-keying workstations supported on the network for machine and/or or human-assisted recognition-processing, and acquisition of shipping information contained in the digital images and the entry of said shipping information into an RDBMS maintained on the network for the purpose of supporting its shipping, tracking, and delivery operations. | 09-04-2008 |