Patent application number | Description | Published |
20080208284 | SYSTEMS AND METHODS FOR NEUROMODULATION USING PRE-RECORDED WAVEFORMS - Methods for neuromodulation using waveform signals. In certain embodiments, an input waveform is obtained from a signal source site in a source subject and an output waveform is applied to a target site in a target subject. The source subject is a human or animal and the signal source site is in the nervous system, including the brain. The source subject and target subject are the same subjects or different subjects. The output waveform is identical to the input waveform or derived from the input waveform. In some embodiments, the output waveform is modified in response to physiologic feedback. Also provided are systems for neuromodulation using waveform signals. | 08-28-2008 |
20080215101 | SYSTEMS AND METHODS FOR TREATING MEDICAL CONDITIONS BY STIMULATION OF MEDIAL THALAMIC REGION - A system for treating medical conditions by neuromodulation of one or more target sites in the nervous system. In certain embodiments, at least one of the target sites is the medial thalamic region, including the intralaminar nucleus and the adjacent white and grey matter. In certain embodiments, where there is more than one target site, the other target sites is elsewhere in the nervous system, including the globus pallidus interna, subthalamic nucleus, corpus callosum, cerebellum, cerebral cortex (including the premotor cortex, motor cortex, and sensory cortex), ventral striatum, lateral thalamus, substantia nigra, and pedunculopontine nuclei. The medical conditions include movement disorders or improvement of movement function, stroke, neuropsychiatric or neuropsychologic disorders, neurodevelopmental disorders, and pain. Methods for treating medical conditions by neuromodulation of the intralaminar nuclei either alone or in combination with another target site(s) is also provided. | 09-04-2008 |
20080288018 | METHODS OF IMPROVING NEUROPSYCHOLOGICAL FUNCTION IN PATIENTS WITH NEUROCOGNITIVE DISORDERS - The present invention provides methods of improving neuropsychological function in a patient having a neurocognitive disorder by chemical or electrically modulating a target site(s) in the ventral striatum/ventral capsule region. Methods also include modulating the treatment based on a closed-loop feedback system that measures bodily activities associated with the neuropsychological function (i.e. that help to determine whether a neuropsychological function is or can be improved. | 11-20-2008 |
Patent application number | Description | Published |
20130013023 | ELECTRICAL STIMULATION OF THE SYMPATHETIC NERVE CHAIN - The present invention provides a method of affecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of affecting a variety of physiological disorders or pathological conditions by placing an electrode adjacent to or in communication with at least one ganglion along the sympathetic nerve chain and stimulating the at least one ganglion until the physiological disorder or pathological condition has been affected. | 01-10-2013 |
20130018436 | ELECTRICAL STIMULATION OF THE SYMPATHETIC NERVE CHAIN - The present invention provides a method of affecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of affecting a variety of physiological disorders or pathological conditions by placing an electrode adjacent to or in communication with at least one ganglion along the sympathetic nerve chain and stimulating the at least one ganglion until the physiological disorder or pathological condition has been affected. | 01-17-2013 |
20130123877 | ELECTRICAL STIMULATION OF THE SYMPATHETIC NERVE CHAIN - The present invention provides a method of affecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of affecting a variety of physiological disorders or pathological conditions by placing an electrode adjacent to or in communication with at least one ganglion along the sympathetic nerve chain and stimulating the at least one ganglion until the physiological disorder or pathological condition has been affected. | 05-16-2013 |
20130131770 | ELECTRICAL STIMULATION OF THE SYMPATHETIC NERVE CHAIN - The present invention provides a method of affecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of affecting a variety of physiological disorders or pathological conditions by placing an electrode adjacent to or in communication with at least one ganglion along the sympathetic nerve chain and stimulating the at least one ganglion until the physiological disorder or pathological condition has been affected. | 05-23-2013 |
20130172953 | METHODS AND SYSTEMS FOR TREATING ACUTE HEART FAILURE BY NEUROMODULATION - Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation. | 07-04-2013 |
20130178829 | METHODS OF TREATING MEDICAL CONDITIONS BY TRANSVASCULAR NEUROMODULATION OF THE AUTONOMIC NERVOUS SYSTEM - The present invention is directed to a method of treating a respiratory or pulmonary condition in a patient by transvascular neuromodulation of an adrenal gland or neural structures that innervate the adrenal gland or components thereof. Methods also include implanting a controller in the patient to control delivery of a therapy signal to the patient's adrenal gland. The therapy signal can be an electrical and/or chemical signal. | 07-11-2013 |
20130274824 | NEUROMODULATORY METHOD FOR TREATING CHRONIC RHINOSINUSITIS - One aspect of the present invention includes a method for treating chronic rhinosinusitis (CRS) in a subject. One step of the method includes implanting a therapy delivery system in the subject so that at least one therapy delivery component of the system is positioned substantially adjacent a target location where modulation of the autonomic nervous system (ANS) is effective to treat CRS. The therapy delivery component includes at least one electrode configured to deliver electric current to the target location. Next, electric current is delivered to the at least one electrode to effect a change in the ANS. | 10-17-2013 |
20130274831 | NEUROMODULATORY METHOD FOR TREATING CHRONIC OR REFRACTORY RHINITIS - One aspect of the present disclosure includes a method for treating chronic or refractory rhinitis in a subject. One step of the method includes implanting a therapy delivery system in the subject so that at least one therapy delivery component of the system is positioned substantially adjacent a target location where modulation of the autonomic nervous system (ANS) is effective to treat chronic or refractory rhinitis. The therapy delivery component includes at least one electrode configured to deliver electric current to the target location. Next, electric current is delivered to the at least one electrode to effect a change in the ANS. | 10-17-2013 |
20130317474 | METHOD OF IMPROVING NEUROPSYCHOLOGICAL FUNCTION IN PATIENTS WITH NEUROCOGNITIVE DISORDERS - The present invention provides methods of improving neuropsychological function in a patient having a neurocognitive disorder by chemical or electrically modulating a target site(s) in the ventral striatum/ventral capsule region. Methods also include modulating the treatment based on a closed-loop feedback system that measures bodily activities associated with the neuropsychological function (i.e. that help to determine whether a neuropsychological function is or can be improved. | 11-28-2013 |
20140052214 | ELECTRICAL STIMULATION OF THE SYMPATHETIC NERVE CHAIN - The present invention provides a method of effecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of effecting a variety of physiological disorders or pathological conditions by placing an electrode adjacent to or in communication with at least one ganglion along the sympathetic nerve chain and stimulating the at least one ganglion until the physiological disorder or pathological condition has been effected. | 02-20-2014 |
20140065107 | DEVICES, SYSTEMS, AND METHODS FOR MODULATING UTERINE FUNCTION - One aspect of the present disclosure relates to a method for modulating uterine function in a mammal. One step of the method includes placing a therapy delivery device into direct contact with a spinal cord target associated with uterine function. Next, the therapy delivery device is activated to deliver a therapy signal to the spinal cord target in an amount and for a time sufficient to effect a change in sympathetic and/or parasympathetic activity in the mammal and thereby modulate uterine function. | 03-06-2014 |
20140067021 | DEVICES, SYSTEMS, AND METHODS FOR TREATING CIRCADIAN RHYTHM DISORDERS - One aspect of the present disclosure relates to a method for treating a circadian rhythm disorder in a mammal. One step of the method includes placing a therapy delivery device into electrical communication with an autonomic nervous system (ANS) nerve target associated with the circadian rhythm disorder. Next, the therapy delivery device is activated to deliver a therapy signal to the ANS nerve target in an amount and for a time sufficient to effect a change in sympathetic and/or parasympathetic activity in the mammal and thereby treat the circadian rhythm disorder. | 03-06-2014 |
20140074069 | METHODS AND SYSTEMS FOR TREATING ACUTE HEART FAILURE BY NEUROMODULATION - Methods of treating acute heart failure in a patient in need thereof. Methods include inserting a therapy delivery device into a pulmonary artery of the patient and applying a therapy signal to autonomic cardiopulmonary fibers surrounding the pulmonary artery. The therapy signal affects heart contractility more than heart rate. Specifically, the application of the therapy signal increases heart contractility and treats the acute heart failure in the patient. The therapy signal can include electrical or chemical modulation. | 03-13-2014 |
20140081355 | APPARATUS, SYSTEMS, AND METHODS FOR TREATING BODY ORGAN AGING - One aspect of the present disclosure relates to a method for treating body organ aging in a mammal. One step of the method includes identifying at least one target organ in need of a therapy signal. Next, a therapy delivery device is placed into electrical communication with an autonomic nervous system (ANS) nerve target and/or a central nervous system (CNS) nerve target associated with the at least one target organ. The therapy delivery device is then activated to deliver the therapy signal to the ANS nerve target and/or the CNS nerve target in an amount and for a time sufficient to effect a change in sympathetic and/or parasympathetic activity associated with the at least one target organ. | 03-20-2014 |
Patent application number | Description | Published |
20100057161 | Methods of Treating Medical Conditions by Neuromodulation of the Cerebellar Pathways - Methods of treating various medical conditions by neuromodulation of target sites of a cerebello-thalamo-cortical pathway and/or a cortical-ponto-cerebellar pathway. Such medical conditions include unilateral motor deficits, movement disorders, psychiatric disorders, epilepsy, speech or cognitive deficits associated with hemispheric lesions, visual deficits associated with hemispheric lesions, learning disorders associated with hemispheric lesions, vertigo and/or dizziness, gait disturbances, hereditary/genetic disorders, congenital malformations, infectious disease, degenerative disorders, autoimmune disorders, and metabolic disorders. A method of enhancing memory, learning and/or cognitive capacity in a normal individual by stimulating a target site of a cerebello-thalamo-cortical pathway and/or a cortical-ponto-cerebellar pathway is also provided. | 03-04-2010 |
20130238068 | CORPUS CALLOSUM NEUROMODULATION ASSEMBLY - Neuromodulation assemblies with lead bodies having curvatures that mimic the curvatures of the splenium, trunk, genu, or rostrum of the corpus callosum. Methods of stimulating the corpus callosum and methods of securing an electrical lead in the brain are also provided. | 09-12-2013 |
Patent application number | Description | Published |
20080228158 | Absorbent article with patterned SBS based adhesive - An SBS based construction adhesive that includes an amount of SIS adhesive to make an SBS/SIS adhesive that shows excellent shear hang time values when used to manufacture disposable absorbent articles. The SBS/SIS adhesive is applied in a spiral pattern having a particular width and frequency to form an endflap seal that may reduce the likelihood of a gel on skin occurrence. | 09-18-2008 |
20100217216 | Absorbent Article - A disposable absorbent article that includes a first and second substrate, a portion of which is joined together with a hot-melt adhesive applied at a temperature of less than 130° C. At least one of the first second substrates has a basis weight of less than 15 grams per square meter. The adhesive provides suitable bond strength on low basis weight substrates and allows for flexible processing conditions. | 08-26-2010 |
20100307668 | METHOD FOR MAINTAINING A FASTENER IN A FOLDED CONFIGURATION - A method for folding a fastener during a high speed manufacturing process and maintaining the fastener in a folded configuration throughout the high speed manufacturing process. The method includes obtaining an article that has a foldable fastener and moving the article in the machine direction during the high speed manufacturing process. The foldable fastener has first and second opposing surfaces, a web and at least one engaging member joined to the web. The method includes applying a frangible bonding agent to a first portion of the first surface of the fastening system; folding the fastening system such that the frangible bonding agent contacts a second portion of the first surface of the fastening system; and allowing the frangible bonding agent to cool at a temperature of less than 60° C. | 12-09-2010 |
20120004630 | Absorbent Article With Low Cold Flow Construction Adhesive - Absorbent articles comprising a low cold flow construction adhesive suitable for joining at least two absorbent article components together, wherein the adhesive comprises an ethylene-based polyolefin resin and certain crystallization enhancers, and wherein the absorbent articles have an in-bag compression opening force of less than about 0.75N. Also, a method for assembling such articles. | 01-05-2012 |
20120209235 | Disposable Absorbent Article Containing An Unapertured Skinless Elastomeric Layer - The present invention relates to a disposable absorbent article comprising a chassis having a front waist region, a back waist region, and a crotch region between the front and back waist regions, said chassis having two opposing longitudinal edges and two perpendicularly placed end edges, said chassis further comprising: | 08-16-2012 |
20130098530 | Method For Maintaining A Fastener In A Folded Configuration - A method for folding a fastener during a high speed manufacturing process and maintaining the fastener in a folded configuration throughout the high speed manufacturing process. The method includes obtaining an article that has a foldable fastener and moving the article in the machine direction during the high speed manufacturing process. The foldable fastener has first and second opposing surfaces, a web and at least one engaging member joined to the web. The method includes applying a frangible bonding agent to a first portion of the first surface of the fastening system; folding the fastening system such that the frangible bonding agent contacts a second portion of the first surface of the fastening system; and allowing the frangible bonding agent to cool at a temperature of less than 60° C. | 04-25-2013 |
20130218114 | Absorbent Article With Low Cold Flow Construction Adhesive - Absorbent articles comprising a low cold flow construction adhesive suitable for joining at least two absorbent article components together, wherein the adhesive comprises an ethylene-based polyolefin resin and a crystallization enhancer, wherein the adhesive is maintained at a temperature from about 100° C. to about 230° C. before application, and wherein the absorbent articles have an in-bag compression opening force of less than about 0.75N. Also, a method for assembling such articles. | 08-22-2013 |
20130245590 | Disposable Absorbent Article Having A Frangible Bonding Agent - A disposable absorbent article that includes a frangible bonding agent for maintaining the absorbent article in a predetermined configuration. The frangible bonding agent may be disposed on a fastening system in order to maintain one or more portions of the fastening system in a particular position during manufacturing but still provide an easy-to-open fastener when used by a consumer. | 09-19-2013 |
20140142532 | DISPOSABLE ABSORBENT ARTICLE HAVING A FRANGIBLE BONDING AGENT - A disposable absorbent article that includes a frangible bonding agent for maintaining the absorbent article in a predetermined configuration. The frangible bonding agent may be disposed on a fastening system in order to maintain one or more portions of the fastening system in a particular position during manufacturing but still provide an easy-to-open fastener when used by a consumer. | 05-22-2014 |
20140180231 | ABSORBENT ARTICLE WITH LOW COLD FLOW CONSTRUCTION ADHESIVE - Absorbent articles comprising a low cold flow construction adhesive suitable for joining at least two absorbent article components together, wherein the adhesive comprises an ethylene-based polyolefin resin and a crystallization enhancer, wherein at least one of the absorbent article components comprises a nonwoven material, and wherein the absorbent articles have an in-bag compression opening force of less than about 0.75N. Also, a method for assembling such articles. | 06-26-2014 |