Patent application number | Description | Published |
20090036434 | Substituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto - The present invention relates to certain substituted aryl and heteroaryl derivative of Formula (I) that are modulators of metabolism. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and complications thereof, such as, diabetes and obesity. | 02-05-2009 |
20100093761 | FUSED-ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO - The present invention relates to certain fused aryl and heteroaryl derivatives of Formula (I) that are modulators of metabolism. | 04-15-2010 |
20100240653 | BIPHENYL SULFONYL AND PHENYL-HETEROARYL SULFONYL MODULATORS OF THE HISTAMINE H3-RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO - The present invention relates to certain biphenyl sulfonamide derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the histamine H3-receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of histamine H3-associated disorders, such as, cognitive disorders, epilepsy, brain trauma, depression, obesity, disorders of sleep and wakefulness such as narcolepsy, shift-work syndrome, drowsiness as a side effect from a medication, maintenance of vigilance to aid in completion of tasks and the like, cataplexy, hypersomnia, somnolence syndrome, jet lag, sleep apnea and the like, attention deficit hyperactivity disorder (ADHD), schizophrenia, allergies, allergic responses in the upper airway, allergic rhinitis, nasal congestion, dementia, Alzheimer's disease and the like. | 09-23-2010 |
20110112060 | 1,2,3-TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO - The present invention relates to certain trisubstituted aryl and heteroaryl derivatives of Formula (I) that are modulators of metabolism. | 05-12-2011 |
20110263592 | IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO - Imidazo[1,2-α]pyridine derivatives of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the 5-HT | 10-27-2011 |
20150353488 | BIPHENYL-ETHYL-PYRROLIDINE DERIVATIVES AS HISTAMINE H3 RECEPTOR MODULATORS FOR THE TREATMENT OF COGNITIVE DISORDERS - The present invention relates to compounds of Formula (Ia) and pharmaceutically acceptable salts, solvates, and hydrates thereof, that modulate the activity of the histamine H3 receptor (Ia). Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of histamine H3-associated disorders. | 12-10-2015 |
Patent application number | Description | Published |
20100138281 | System and method for retail store shelf stock monitoring, predicting, and reporting - A system for retail store shelf stock status monitoring, predicting, and reporting that is capable of monitoring retail store current shelf stock capacity and shelf product freshness at product level, category level, department level, store level, and other product hierarchy levels. It is also capable of intelligently predicting future shelf stock status according to predicted future store sales activities. It uses shelf stock empty index, out-of-stock alert, shelf stock freshness, shelf stock expiration alert, and other shelf stock performance measures to present current shelf status, future shelf status, and past shelf stock performances through interactive store maps and other visual presentation means to optimally deliver retail store shelf stock performance information in real time. The system empowers store clerks, store managers, chain store management, and corporation analysts to monitor, review, and analyze store shelf stock status in real time from anywhere at any time. | 06-03-2010 |
20100205045 | System and method for improving retail store customer loyalty - A system and method for improving and maintaining retail store customer loyalty through providing customers with quality services, timely assistances, and conveniences in all stages of product shopping. The system provides a web parts based collaborative online platform for retailers, product manufacturers, and service providers to share resources, distribute coupons, promote products and services, and communicate with customers. It further provides shopping assistances to help customers selectively receive coupons, redeem coupons online, build shopping lists online, retrieve shopping list and shopping reminders, find product shelf locations, place online orders, and manage budgets and nutrition. The system has the capability to collect customer shopping activity data, automatically analyze customer product purchase preferences, recommend products and services, and deliver relevant coupons and advertisements to customers. | 08-12-2010 |
20140148013 | ACTIVELY HEATED ALUMINUM BAFFLE COMPONENT HAVING IMPROVED PARTICLE PERFORMANCE AND METHODS OF USE AND MANUFACTURE THEREOF - An actively heated aluminum baffle component such as a thermal control plate or baffle ring of a showerhead electrode assembly of a plasma processing chamber has an exposed outer aluminum oxide layer which is formed by an electropolishing procedure. The exposed outer aluminum oxide layer minimizes defects and particles generated as a result of differential thermal stresses experienced by the aluminum component and outer aluminum oxide layer during plasma processing compared to an identically shaped component having a Type III anodized surface. | 05-29-2014 |
Patent application number | Description | Published |
20130298942 | ETCH REMNANT REMOVAL - Methods of removing residual polymer from vertical walls of a patterned dielectric layer are described. The methods involve the use of a gas phase etch to remove the residual polymer without substantially disturbing the patterned dielectric layer. The gas phase etch may be used on a patterned low-k dielectric layer and may maintain the low dielectric constant of the patterned dielectric layer. The gas phase etch may further avoid stressing the patterned low-k dielectric layer by avoiding the use of liquid etchants whose surface tension can upset delicate low-K features. The gas phase etch may further avoid the formation of solid etch by-products which cars also deform the delicate features. | 11-14-2013 |
20140141621 | DRY-ETCH SELECTIVITY - A method of etching exposed patterned heterogeneous structures is described and includes a remote plasma etch formed from a reactive precursor. The plasma power is pulsed rather than left on continuously. Plasma effluents from the remote plasma are flowed into a substrate processing region where the plasma effluents selectively remove one material faster than another. The etch selectivity results from the pulsing of the plasma power to the remote plasma region, which has been found to suppress the number of ionically-charged species that reach the substrate. The etch selectivity may also result from the presence of an ion suppression element positioned between a portion of the remote plasma and the substrate processing region. | 05-22-2014 |
20140262755 | UV-ASSISTED REACTIVE ION ETCH FOR COPPER - In some embodiments, a plasma etching apparatus is provided for etching copper that includes (1) a chamber body having a process chamber adapted to receive a substrate; (2) an RF source coupled to an RF electrode; (3) a pedestal located in the processing chamber and adapted to support a substrate; and (4) a UV source configured to delivery UV light to the processing chamber during at least a portion of an etch process performed within the plasma etching apparatus. Numerous other aspects are provided. | 09-18-2014 |
20140273487 | PULSED DC PLASMA ETCHING PROCESS AND APPARATUS - In one aspect, a plasma etching apparatus is disclosed. The plasma etching apparatus includes a chamber body having a process chamber adapted to receive a substrate, an RF source coupled to an RF electrode, a pedestal located in the processing chamber and adapted to support a substrate, a plurality of conductive pins adapted to contact and support the substrate during processing, and a DC bias source electrically coupled to the plurality of conductive pins. Etching methods are provided, as are numerous other aspects. | 09-18-2014 |
20150056800 | Self-aligned interconnects formed using substractive techniques - A method of forming an interconnect structure for semiconductor or MEMS structures at a 10 nm Node (16 nm HPCD) down to 5 nm Node (7 nm HPCD), or lower, where the conductive contacts of the interconnect structure are fabricated using solely subtractive techniques applied to conformal layers of conductive materials. | 02-26-2015 |
20150099369 | PROCESS FOR ETCHING METAL USING A COMBINATION OF PLASMA AND SOLID STATE SOURCES - An apparatus configured to remove metal etch byproducts from the surface of substrates and from the interior of a substrate processing chamber. A plasma is used in combination with a solid state light source, such as an LED, to desorb metal etch byproducts. The desorbed byproducts may then be removed from the chamber. | 04-09-2015 |
20150132968 | DRY-ETCH SELECTIVITY - A method of etching exposed patterned heterogeneous structures is described and includes a remote plasma etch formed from a reactive precursor. The plasma power is pulsed rather than left on continuously. Plasma effluents from the remote plasma are flowed into a substrate processing region where the plasma effluents selectively remove one material faster than another. The etch selectivity results from the pulsing of the plasma power to the remote plasma region, which has been found to suppress the number of ionically-charged species that reach the substrate. The etch selectivity may also result from the presence of an ion suppression element positioned between a portion of the remote plasma and the substrate processing region. | 05-14-2015 |
20150140827 | METHODS FOR BARRIER LAYER REMOVAL - Implementations described herein generally relate to semiconductor manufacturing and more particularly to methods for etching a low-k dielectric barrier layer disposed on a substrate using a non-carbon based approach. In one implementation, a method for etching a barrier low-k layer is provided. The method comprises (a) exposing a surface of the low-k barrier layer to a treatment gas mixture to modify at least a portion of the low-k barrier layer and (b) chemically etching the modified portion of the low-k barrier layer by exposing the modified portion to a chemical etching gas mixture, wherein the chemical etching gas mixture includes at least an ammonium gas and a nitrogen trifluoride gas or at least a hydrogen gas and a nitrogen trifluoride gas. | 05-21-2015 |
20150147879 | ULTRA-THIN STRUCTURE TO PROTECT COPPER AND METHOD OF PREPARATION - Methods of depositing thin, low dielectric constant layers that are effective diffusion barriers on metal interconnects of semiconductor circuits are described. A self-assembled monolayer (SAM) of molecules each having a head moiety and a tail moiety are deposited on the metal. The SAM molecules self-align, wherein the head moiety is formulated to selectively bond to the metal layer leaving the tail moiety disposed at a distal end of the molecule. A dielectric layer is subsequently deposited on the SAM, chemically bonding to the tail moiety of the SAM molecules. | 05-28-2015 |
20150214101 | METHODS FOR ETCHING A DIELECTRIC BARRIER LAYER IN A DUAL DAMASCENE STRUCTURE - Methods for eliminating early exposure of a conductive layer in a dual damascene structure and for etching a dielectric barrier layer in the dual damascene structure are provided. In one embodiment, a method for etching a dielectric barrier layer disposed on a substrate includes patterning a substrate having a dielectric bulk insulating layer disposed on a dielectric barrier layer using a hardmask layer disposed on the dielectric bulk insulating layer as an etching mask, exposing a portion of the dielectric barrier layer after removing the dielectric bulk insulating layer uncovered by the dielectric bulk insulating layer, removing the hardmask layer from the substrate, and subsequently etching the dielectric barrier layer exposed by the dielectric bulk insulating layer. | 07-30-2015 |
20150221596 | DIELECTRIC/METAL BARRIER INTEGRATION TO PREVENT COPPER DIFFUSION - An interconnect structure for use in semiconductor devices and a method for fabricating the same is described. The method includes positioning a substrate in a vacuum processing chamber. The substrate has an exposed copper surface and an exposed low-k dielectric surface. A metal layer is formed over the copper surface but not over the low-k dielectric surface. A metal-based dielectric layer is formed over the metal layer and the low-k dielectric layer. | 08-06-2015 |
20150255329 | METHODS FOR FORMING PASSIVATION PROTECTION FOR AN INTERCONNECTION STRUCTURE - Methods for forming a passivation protection structure on a metal line layer formed in an insulating material in an interconnection structure are provided. In one embodiment, a method for forming passivation protection on a metal line in an interconnection structure for semiconductor devices includes selectively forming a metal capping layer on a metal line bounded by a dielectric bulk insulating layer in an interconnection structure formed on a substrate in a processing chamber incorporated in a multi-chamber processing system, in-situ forming a barrier layer on the substrate in the processing chamber; wherein the barrier layer is a metal dielectric layer, and forming a dielectric capping layer on the barrier layer in the multi-chamber processing system. | 09-10-2015 |
20150262869 | METHODS FOR FORMING INTERCONNECTION STRUCTURES IN AN INTEGRATED CLUSTER SYSTEM FOR SEMICONDCUTOR APPLICATIONS - Embodiments of the present invention provide methods for forming an interconnection structure in semiconductor devices without breaking vacuum with minimum oxidation/atmosphere exposure. In one embodiment, a method for forming an interconnection structure for semiconductor devices includes supplying a barrier layer etching gas mixture into a first processing chamber having a substrate disposed therein to etch portions of a barrier layer exposed by a patterned metal layer until the underlying substrate is exposed, the first processing chamber disposed in a processing system, and forming a liner layer on the substrate covering the etched barrier layer in a second processing chamber disposed in the processing system. | 09-17-2015 |
20150279726 | INTEGRATED METAL SPACER AND AIR GAP INTERCONNECT - Embodiments described herein relate to methods for forming an air gap interconnect. A metal spacer layer is conformally deposited on a substrate having mandrel structures formed thereon. The metal spacer layer is etched to form spacer features and the mandrel structures are removed from the substrate. Various other dielectric deposition, patterning and etching steps may be performed to desirably pattern materials present on the substrate. Ultimately, a trench is formed between adjacent spacer features and a capping layer is deposited over the trench to form an air gap between the adjacent spacer features. For packaging purposes, an interconnect via may be configured to contact at least one of the spacer features adjacent the air gap. | 10-01-2015 |
20150357183 | METHODS FOR FORMING INTERCONNECT STRUCTURE UTILIZING SELECTIVE PROTECTION PROCESS FOR HARDMASK REMOVAL PROCESS - Methods and apparatuses for forming a dual damascene structure utilizing a selective protection process to protect vias and/or trenches in the dual damascene structure while removing a hardmask layer from the dual damascene structure. In one embodiment, a method for removing a patterned hardmask layer from a substrate includes forming an organic polymer material on a dual damascene structure that exposes substantially a patterned hardmask layer disposed on an upper surface of the dual damascene structure, removing the patterned hardmask layer on the substrate, and removing the organic polymer material from the substrate. | 12-10-2015 |
Patent application number | Description | Published |
20100157086 | DYNAMIC AUTOFOCUS METHOD AND SYSTEM FOR ASSAY IMAGER - A method and system are provided for controlling focus dynamically of a sample imager. The method comprises scanning a sample with an optical assembly that apportions the sample into regions based on a scan pattern. The optical assembly has a focal setting with respect to the sample. The method further comprises shifting the focal setting of the optical assembly during scanning of the sample, and detecting one or more images representative of one of the regions from the sample. The one or more images have associated degrees of focus corresponding to the focal setting of the optical assembly. The method analyzes the image(s) to obtain a focus score or scores corresponding thereto, where the focus scores represent a degree to which the optical assembly was in focus when detecting the images. The method adjusts the focus setting based on the focus score(s). | 06-24-2010 |
20110105356 | COMPOSITIONS AND METHODS FOR PROVIDING SUBSTANCES TO AND FROM AN ARRAY - Methods, kits, systems, and multilayer transfer media for transferring a substance to and from an array are disclosed herein. Also disclosed herein are methods of detecting a substance that has been transferred to an array. | 05-05-2011 |
20130235388 | DYNAMIC AUTOFOCUS METHOD AND SYSTEM FOR ASSAY IMAGER - Method of detecting surface features of a microarray. The method includes providing a microarray to an optical scanner, wherein the microarray includes a surface having features. The method also includes carrying out a scanning process using the optical scanner, wherein the scanning process includes: (i) acquiring images of sequential regions on the surface, wherein a defocus spread is applied to the optical scanner during the acquiring, (ii) determining a focus score for the images, (iii) adjusting the optical scanner to a different defocus spread based on the focus score, and (iv) repeating (i) through (iii) at the different defocus spread, thereby acquiring images of further sequential regions on the surface. The method also includes analyzing the images to distinguish different target molecules at the features of the microarray. The images that are analyzed were acquired at the defocus spread and at the different defocus spread during the scanning process. | 09-12-2013 |
20140079923 | POLYMER COATINGS - The present disclosure relates to polymer coatings covalently attached to the surface of a substrate and the preparation of the polymer coatings, such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM), in the formation and manipulation of substrates, such as molecular arrays and flow cells. The present disclosure also relates to methods of preparing a substrate surface by using beads coated with a covalently attached polymer, such as PAZAM, and the method of determining a nucleotide sequence of a polynucleotide attached to a substrate surface described herein. | 03-20-2014 |
20150259735 | POLYMER COATINGS - The present disclosure relates to polymer coatings covalently attached to the surface of a substrate and the preparation of the polymer coatings, such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM), in the formation and manipulation of substrates, such as molecular arrays and flow cells. The present disclosure also relates to methods of preparing a substrate surface by using beads coated with a covalently attached polymer, such as PAZAM, and the method of determining a nucleotide sequence of a polynucleotide attached to a substrate surface described herein. | 09-17-2015 |
Patent application number | Description | Published |
20100017763 | Stochastic Steady State Circuit Analyses - A method for simulating a system without a time invariant or periodically time-varying steady state is provided. The method limits the number of states included in a Markov chain model by discretizing the states based on Gaussian decomposition, utilizes a state exploration algorithm that discovers only recurrent states, and/or utilizes a state truncation algorithm that eliminates states with negligible stationary probabilities. | 01-21-2010 |
20100046600 | Methods and Circuits for Asymmetric Distribution of Channel Equalization Between Devices - A transceiver architecture supports high-speed communication over a signal lane that extends between a high-performance integrated circuit (IC) and one or more relatively low-performance ICs employing less sophisticated transmitters and receivers. The architecture compensates for performance asymmetry between ICs communicating over a bidirectional lane by instantiating relatively complex transmit and receive equalization circuitry on the higher-performance side of the lane. Both the transmit and receive equalization filter coefficients in the higher-performance IC may be adaptively updated based upon the signal response at the receiver of the higher-performance IC. | 02-25-2010 |
20100103999 | PARTIAL RESPONSE DECISION-FEEDBACK EQUALIZATION WITH ADAPTATION BASED ON EDGE SAMPLES | 04-29-2010 |
20100135378 | Receiver with Clock Recovery Circuit and Adaptive Sample and Equalizer Timing - A receiver is equipped with an adaptive phase-offset controller and associated timing-calibration circuitry that together shift the timing for a data sampler and a digital equalizer. The sample and equalizer timing is shifted to a position with less residual inter-symbol interference (ISI) energy relative to the current symbol. The shifted position may be calculated using a measure of signal quality, such as a receiver bit-error rate or a comparison of filter-tap values, to optimize the timing of data recovery. | 06-03-2010 |
20100272215 | Signaling with Superimposed Differential-Mode and Common-Mode Signals - A data receiver circuit ( | 10-28-2010 |
20110084737 | FREQUENCY RESPONSIVE BUS CODING - A data system permits bus encoding based on frequency of the bus and the frequency of switching on the bus so as to avoid undesirable frequency conditions such as a resonant condition or interference with other electrical devices. Transmission frequencies along one or more busses are monitored and used to control the encoding process, for example, an encoding process based on data bus inversion (DBI). The use of both a measure of an absolute number of logic levels (“DBI_DC”) and a measure of a number of logic level transitions relative to a prior signal (“DBI_AC”) provides a measure of control that may be used to compensate for both main and predriver switching noise. | 04-14-2011 |
20110142112 | Signaling with Superimposed Clock and Data Signals - A data transmission circuit includes a clock driver to obtain a clock signal having a first rate and to drive the clock signal onto one or more transmission lines. The data transmission circuit also includes a timing circuit to obtain the clock signal and to generate a symbol clock having a second rate. The first rate is a multiple of the second rate, wherein the multiple is greater than one. The data transmission circuit further includes a data driver synchronized to the symbol clock. The data driver obtains a data signal and drives the data signal onto the one or more transmission lines at the second rate. The data signal and the clock signal are driven onto the one or more transmission lines simultaneously. | 06-16-2011 |
20110222594 | Methods and Circuits for Asymmetric Distribution of Channel Equalization Between Devices - A transceiver architecture supports high-speed communication over a signal lane that extends between a high-performance integrated circuit (IC) and one or more relatively low-performance ICs employing less sophisticated transmitters and receivers. The architecture compensates for performance asymmetry between ICs communicating over a bidirectional lane by instantiating relatively complex transmit and receive equalization circuitry on the higher-performance side of the lane. Both the transmit and receive equalization filter coefficients in the higher-performance IC may be adaptively updated based upon the signal response at the receiver of the higher-performance IC. | 09-15-2011 |
20130162460 | HIGH-ACCURACY DETECTION IN COLLABORATIVE TRACKING SYSTEMS - An electronic device for wirelessly tracking the position of a second electronic device is disclosed. The electronic device includes transceiver circuitry and processing circuitry. The transceiver circuitry includes a beacon generator to generate a beacon at a particular frequency and direction. An antenna array transmits the beacon, and receives at least one modulated reflected beacon from the second electronic device. The transceiver circuitry also includes a discriminator to discriminate between received modulated reflected beacons and received reflected interfering beacons. The processing circuitry couples to the transceiver circuitry and tracks the position of the second device based on the modulated reflected beacons. | 06-27-2013 |
20130249612 | METHOD AND APPARATUS FOR SOURCE-SYNCHRONOUS SIGNALING - A low-power, high-performance source-synchronous chip interface which provides rapid turn-on and facilitates high signaling rates between a transmitter and a receiver located on different chips is described in various embodiments. Some embodiments of the chip interface include, among others: a segmented “fast turn-on” bias circuit to reduce power supply ringing during the rapid power-on process; current mode logic clock buffers in a clock path of the chip interface to further reduce the effect of power supply ringing; a multiplying injection-locked oscillator (MILO) clock generator to generate higher frequency clock signals from a reference clock; a digitally controlled delay line which can be inserted in the clock path to mitigate deterministic jitter caused by the MILO clock generator; and circuits for periodically re-evaluating whether it is safe to retime transmit data signals in the reference clock domain directly with the faster clock signals. | 09-26-2013 |
20140016692 | EDGE BASED PARTIAL RESPONSE EQUALIZATION - A device implements data reception with edge-based partial response decision feedback equalization. In an example embodiment, the device implements a tap weight adapter circuit that sets the tap weights that are used for adjustment of a received data signal. The tap weight adapter circuit sets the tap weights based on previously determined data values and input from an edge analysis of the received data signal using a set of edge samplers. The edge analysis may include adjusting the sampled data signal by the tap weights determined by the tap weight adapter circuit. A clock generation circuit generates an edge clock signal to control the edge sampling performed by the set of edge samplers. The edge clock signal may be generated as a function of the signals of the edge samplers and prior data values determined by the equalizer. | 01-16-2014 |
20140152357 | METHODS AND CIRCUITS FOR REDUCING CLOCK JITTER - A communication system includes a continuous-time linear equalizer in the clock forward path. The equalizer may be adjusted to minimize clock jitter, including jitter associated with the first few clock edges after the clock signal is enabled. Reducing early-edge jitter reduces the power and circuit complexity otherwise needed to turn the system on quickly. | 06-05-2014 |
20140153631 | METHODS AND CIRCUITS FOR ASYMMETRIC DISTRIBUTION OF CHANNEL EQUALIZATION BETWEEN DEVICES - A transceiver architecture supports high-speed communication over a signal lane that extends between a high-performance integrated circuit (IC) and one or more relatively low-performance ICs employing less sophisticated transmitters and receivers. The architecture compensates for performance asymmetry between ICs communicating over a bidirectional lane by instantiating relatively complex transmit and receive equalization circuitry on the higher-performance side of the lane. Both the transmit and receive equalization filter coefficients in the higher-performance IC may be adaptively updated based upon the signal response at the receiver of the higher-performance IC. | 06-05-2014 |
20140169438 | Receiver with Clock Recovery Circuit and Adaptive Sample and Equalizer Timing - A receiver is equipped with an adaptive phase-offset controller and associated timing-calibration circuitry that together shift the timing for a data sampler and a digital equalizer. The sample and equalizer timing is shifted to a position with less residual inter-symbol interference (ISI) energy relative to the current symbol. The shifted position may be calculated using a measure of signal quality, such as a receiver bit-error rate or a comparison of filter-tap values, to optimize the timing of data recovery. | 06-19-2014 |
20140210683 | CALIBRATING A RETRO-DIRECTIVE ARRAY FOR AN ASYMMETRIC WIRELESS LINK - The disclosed embodiments relate to a technique for calibrating a retro-directive array. During the calibration process, the system measures a gain g | 07-31-2014 |
20140347108 | METHOD AND APPARATUS FOR SOURCE-SYNCHRONOUS SIGNALING - A low-power, high-performance source-synchronous chip interface which provides rapid turn-on and facilitates high signaling rates between a transmitter and a receiver located on different chips is described in various embodiments. Some embodiments of the chip interface include, among others: a segmented “fast turn-on” bias circuit to reduce power supply ringing during the rapid power-on process; current mode logic clock buffers in a clock path of the chip interface to further reduce the effect of power supply ringing; a multiplying injection-locked oscillator (MILO) clock generator to generate higher frequency clock signals from a reference clock; a digitally controlled delay line which can be inserted in the clock path to mitigate deterministic jitter caused by the MILO clock generator; and circuits for periodically re-evaluating whether it is safe to retime transmit data signals in the reference clock domain directly with the faster clock signals. | 11-27-2014 |
20150036732 | EDGE BASED PARTIAL RESPONSE EQUALIZATION - A method is disclosed. The method includes sampling a data signal having a voltage value at an expected edge time of the data signal. A first alpha value is generated, and a second alpha value generated in dependence upon the voltage value. The data signal is adjusted by the first alpha value to derive a first adjusted signal. The data signal is adjusted by the second alpha value to derive a second adjusted signal. The first adjusted signal is sampled to output a first data value while the second adjusted signal is sampled to output a second data value. A selection is made between the first data value and the second data value as a function of a prior received data value to determine a received data value. | 02-05-2015 |
20150036775 | METHODS AND CIRCUITS FOR REDUCING CLOCK JITTER - A communication system includes a continuous-time linear equalizer in the clock forward path. The equalizer may be adjusted to minimize clock jitter, including jitter associated with the first few clock edges after the clock signal is enabled. Reducing early-edge jitter reduces the power and circuit complexity otherwise needed to turn the system on quickly. | 02-05-2015 |
20150049798 | RECEIVER WITH ENHANCED ISI MITIGATION - A receiver integrated circuit is disclosed that includes a filter and a linear equalization circuit. The filter has an input to receive a signal symbols a main tap and a pre-cursor tap to reduces a pre-cursor ISI acting on the data symbols. The linear equalization circuit couples to the output and cooperates with the filter to further reduce ISI. | 02-19-2015 |
20150078495 | Clock and Data Recovery Having Shared Clock Generator - This disclosure provides a clock recovery circuit for a multi-lane communication system. Local clocks are recovered from the input signals using respective local CDR circuits, and associated CDR error signals are aggregated or otherwise combined. A global recovered clock for shared use by the local CDR circuits is generated at a controllable oscillation frequency as a function of a combination of the error signals from the plurality of receivers. A voltage- or current-controlled delay line can also be used to phase adjust the global recovered clock to mitigate band-limited, lane-correlated, high frequency jitter. | 03-19-2015 |
20150349986 | METHODS AND CIRCUITS FOR ASYMMETRIC DISTRIBUTION OF CHANNEL EQUALIZATION BETWEEN DEVICES - A transceiver architecture supports high-speed communication over a signal lane that extends between a high-performance integrated circuit (IC) and one or more relatively low-performance ICs employing less sophisticated transmitters and receivers. The architecture compensates for performance asymmetry between ICs communicating over a bidirectional lane by instantiating relatively complex transmit and receive equalization circuitry on the higher-performance side of the lane. Both the transmit and receive equalization filter coefficients in the higher-performance IC may be adaptively updated based upon the signal response at the receiver of the higher-performance IC. | 12-03-2015 |
Patent application number | Description | Published |
20140270530 | DUPLICATE/NEAR DUPLICATE DETECTION AND IMAGE REGISTRATION - Embodiments are disclosed for detecting duplicate and near duplicate images. An exemplary method includes receiving an original image, preparing the image for fingerprinting, and calculating an image fingerprint, the fingerprint expressed as a sequence of numbers. The method further includes comparing the image fingerprint thus obtained with a set of previously stored fingerprints obtained from a set of previously stored images, and determining if the original image is either a duplicate or a near duplicate of an image in the set if the dissimilarity between the two fingerprints is less than a defined threshold T. Once a duplicate or near duplicate is detected, various defined actions may be taken, including culling the less desirable image or referring the redundancy to a user. | 09-18-2014 |
20140270547 | PRESENTATION AND ORGANIZATION OF CONTENT - Embodiments are provided for organization and presentation of content. In some embodiments, a plurality of images and a plurality of similarity rules for image categorization are received. For each image in the plurality of images, the image from the plurality and each remaining image from the plurality is compared by: applying each similarity rule to the image and a remaining image from the plurality to obtain a numeric result, and recording the numeric result for the two images in a numeric representation, the numeric representation embodying similarities found between each of the plurality of images. The numeric representation is used as a reference for clustering the plurality of images into clusters of similar images, and each image is stored with a marker denoting a cluster to which it has been assigned. | 09-18-2014 |
20140270550 | PRESENTATION AND ORGANIZATION OF CONTENT - Embodiments are provided for organization and presentation of content. In some embodiments, a plurality of images and a plurality of similarity rules for image categorization are received. For each image in the plurality of images, that image and each remaining image from the plurality is compared by: applying each similarity rule to the image and a remaining image from the plurality to obtain a numeric result, and recording the numeric result for the pair of images in a numeric representation, the numeric representation embodying similarities. The numeric representation is used as a reference for clustering the plurality of images into clusters of similar images, and each image is stored with a marker denoting a cluster to which it has been assigned. | 09-18-2014 |
20140270571 | SHUFFLE ALGORITHM AND NAVIGATION - Embodiments are disclosed for randomly and pseudo-randomly presenting images to a user. An exemplary method includes receiving a first set of images from a user, receiving a second set of conditions that an image must satisfy, creating a subset of the first set of images that satisfies the second set of conditions, selecting a random element of said subset, and displaying said random element to a user. The conditions define the breadth or narrowness of the subset of images from which a random element is chosen. The conditions may be system set, user configured, or any combination, and a user may repeat the process, or may choose to view a new image that has one or more affinities to the last randomly chosen image presented. Affinities function in similar manner to the conditions of a pseudo-random selection, but generally serve to narrow the available set of photos to a greater extent. Conditions or affinities may be, for example, time based, location based, event based, based on a relationship of the user to a person appearing in the last displayed photo, or based upon various other defined connections or commonalities. | 09-18-2014 |
20140282901 | MANAGING SHARED CONTENT WITH A CONTENT MANAGEMENT SYSTEM - Embodiments are provided for managing shared content with a content management system. In some embodiments, a request is received for a history of content shares for an authenticated account, at least one content share is retrieved for the authenticated account, the at least one content share having at least one shared item and at least one recipient identifier, information on the at least one content share on a user interface is displayed, and a request is received to modify the at least one content share and updating the at least one content share in response to the request. | 09-18-2014 |
20160026896 | PRESENTATION AND ORGANIZATION OF CONTENT - Embodiments are provided for organization and presentation of content. In some embodiments, a plurality of images and a plurality of similarity rules for image categorization are received. For each image in the plurality of images, that image and each remaining image from the plurality is compared by: applying each similarity rule to the image and a remaining image from the plurality to obtain a numeric result, and recording the numeric result for the pair of images in a numeric representation, the numeric representation embodying similarities. The numeric representation is used as a reference for clustering the plurality of images into clusters of similar images, and each image is stored with a marker denoting a cluster to which it has been assigned. | 01-28-2016 |
20160041722 | SYSTEMS AND METHODS FOR PROCESSING ORDERS OF CONTENT ITEMS - Various embodiments of the present disclosure can include systems, methods, and non-transitory computer readable media configured to highlight, by a computing system, a reference content item of a plurality of content items associated with a story in response to a selection of the reference content item, the plurality of content items having a first order. The reference content item may be reranked relative to the plurality of content items in response to user input to create a second order of the plurality of content items. The story may be published using the second order of the plurality of content items. | 02-11-2016 |
20160041723 | SYSTEMS AND METHODS FOR MANIPULATING ORDERED CONTENT ITEMS - Various embodiments of the present disclosure can include systems, methods, and non-transitory computer readable media configured to display, by a computing system, an arrangement of a plurality of content items in a first order. A reference content item may be highlighted at an initial position in the arrangement in response to a selection of the reference content item. The reference content item may be moved to another position in the arrangement in response to a motion input relating to the reference content item to create a second order of the plurality of content items. An arrangement of the plurality of content items may be displayed in the second order. | 02-11-2016 |
Patent application number | Description | Published |
20120278801 | MAINTAINING HIGH AVAILABILITY OF A GROUP OF VIRTUAL MACHINES USING HEARTBEAT MESSAGES - Embodiments maintain high availability of software application instances in a fault domain. Subordinate hosts are monitored by a master host. The subordinate hosts publish heartbeats via a network and datastores. Based at least in part on the published heartbeats, the master host determines the status of each subordinate host, distinguishing between subordinate hosts that are entirely inoperative and subordinate hosts that are operative but partitioned (e.g., unreachable via the network). The master host may restart software application instances, such as virtual machines, that are executed by inoperative subordinate hosts or that cease executing on partitioned subordinate hosts. | 11-01-2012 |
20140059379 | PROACTIVE RESOURCE RESERVATION FOR PROTECTING VIRTUAL MACHINES - A system for proactive resource reservation for protecting virtual machines. The system includes a cluster of hosts, wherein the cluster of hosts includes a master host, a first slave host, and one or more other slave hosts, and wherein the first slave host executes one or more virtual machines thereon. The first slave host is configured to identify a failure that impacts an ability of the one or more virtual machines to provide service, and calculate a list of impacted virtual machines. The master host is configured to receive a request to reserve resources on another host in the cluster of hosts to enable the impacted one or more virtual machines to failover, calculate a resource capacity among the cluster of hosts, determine whether the calculated resource capacity is sufficient to reserve the resources, and send an indication as to whether the resources are reserved. | 02-27-2014 |
20140059380 | PROTECTING PAIRED VIRTUAL MACHINES - A system for monitoring virtual machines includes a master host and a slave host. The slave host includes a primary virtual machine and a secondary virtual machine. The slave host is configured to identify a failure that impacts an ability of at least one of the primary virtual machine and the secondary virtual machine to provide service. If the failure is a Permanent Device Loss failure, the slave host is configured to terminate each impacted virtual machine. If the failure is an All Paths Down failure, the master host is configured to apply one of the following: a first remedy if the primary virtual machine is impacted and the secondary virtual machine is not impacted; a second remedy if the secondary virtual machine is impacted and the primary virtual machine is not impacted; or a third remedy if both the primary virtual machine and the secondary virtual machine are impacted. | 02-27-2014 |
20140059392 | PROTECTING VIRTUAL MACHINES AGAINST STORAGE CONNECTIVITY FAILURES - A system for monitoring a virtual machine executed on a host. The system includes a processor that receives an indication that a failure caused a storage device to be inaccessible to the virtual machine, the inaccessible storage device impacting an ability of the virtual machine to provide service, and applies a remedy to restore access to the storage device based on a type of the failure. | 02-27-2014 |
20140344805 | Managing Availability of Virtual Machines in Cloud Computing Services - Recovery of virtual machines when one or more hosts fail includes identifying virtual machines running on the remaining functioning hosts. Some of the identified powered on virtual machines are suspended in favor of restarting some of the failed virtual machines from the failed host(s). A subsequent round of identifying virtual machines for suspension and virtual machines for restarting is performed. Virtual machines for suspension and restarting may be identified based on their associated “recovery time objective” (RTO) values or their “maximum number of RTO violations” value. | 11-20-2014 |
20150089272 | MAINTAINING HIGH AVAILABILITY OF A GROUP OF VIRTUAL MACHINES USING HEARTBEAT MESSAGES - Embodiments maintain high availability of software application instances in a fault domain. Subordinate hosts are monitored by a master host. The subordinate hosts publish heartbeats via a network and datastores. Based at least in part on the published heartbeats, the master host determines the status of each subordinate host, distinguishing between subordinate hosts that are entirely inoperative and subordinate hosts that are operative but partitioned (e.g., unreachable via the network). The master host may restart software application instances, such as virtual machines, that are executed by inoperative subordinate hosts or that cease executing on partitioned subordinate hosts. | 03-26-2015 |
20150154046 | INTERDEPENDENT VIRTUAL MACHINE MANAGEMENT - Exemplary methods, apparatuses, and systems determine a list of virtual machines to be subject to a corrective action. When one or more of the listed virtual machines have dependencies upon other virtual machines, network connections, or storage devices, the determination of the list includes determining that the dependencies of the one or more virtual machines have been met. An attempt to restart or take another corrective action for the first virtual machine within the list is made. A second virtual machine that is currently deployed and running or powered off or paused in response to the corrective action for the first virtual machine is determined to be dependent upon the first virtual machine. In response to the second virtual machine's dependencies having been met by the attempt to restart or take corrective action for the first virtual machine, the second virtual machine is added to the list of virtual machines. | 06-04-2015 |
20160085582 | INTERDEPENDENT VIRTUAL MACHINE MANAGEMENT - Exemplary methods, apparatuses, and systems determine a list of virtual machines to be subject to a corrective action. When one or more of the listed virtual machines have dependencies upon other virtual machines, network connections, or storage devices, the determination of the list includes determining that the dependencies of the one or more virtual machines have been met. An attempt to restart or take another corrective action for the first virtual machine within the list is made. A second virtual machine that is currently deployed and running or powered off or paused in response to the corrective action for the first virtual machine is determined to be dependent upon the first virtual machine. In response to the second virtual machine's dependencies having been met by the attempt to restart or take corrective action for the first virtual machine, the second virtual machine is added to the list of virtual machines. | 03-24-2016 |
Patent application number | Description | Published |
20110090221 | 3D NAVIGATION METHODS USING NONPHOTOREALISTIC (NPR) 3D MAPS - A method of displaying a navigation map includes automatically determining a location of a vehicle. Three-dimensional or 2D data associated with buildings surrounding the vehicle is identified. A nonphotorealistic image of 3D objects around the vehicle is rendered based on the data. The nonphotorealistic image is electronically displayed to a user. | 04-21-2011 |
20110140928 | METHOD FOR RE-USING PHOTOREALISTIC 3D LANDMARKS FOR NONPHOTOREALISTIC 3D MAPS - A method of displaying a navigation map includes preprocessing photorealistic three- dimensional data offline. A location of a vehicle is automatically determined online. A portion of the preprocessed photorealistic three-dimensional data is identified that is associated with objects that are disposed within a geographic area. The geographic area includes the location of the vehicle. A nonphotorealistic image is rendered based on the identified portion of the preprocessed data. The nonphotorealistic image is electronically displayed to a user within the vehicle. | 06-16-2011 |
20110144909 | PERSONALIZED AND CONTEXT-SENSITIVE 3D ROUTE GUIDANCE - A method of displaying a navigation map includes determining a route of a vehicle. Three-dimensional data is received. The data is associated with buildings that are disposed within a geographic area. The geographic area includes the route of the vehicle. At least one of the buildings in the data that is adjacent to at least one street of the route is rendered in a first opaque visual style. All of the buildings in the data that are nonadjacent to at least one street of the route are rendered in at least one second visual style different from the first opaque visual style. | 06-16-2011 |
20110166783 | STYLIZED PROCEDURAL MODELING FOR 3D NAVIGATION - A method of displaying a navigation map includes determining a route of a vehicle. A two-dimensional footprint of a building disposed within a geographic area is received within the vehicle. The geographic area includes the route of the vehicle. Attribute information associated with the building is received. The attribute information is received within the vehicle. A visual representation of the building is rendered based upon the two-dimensional footprint and the attribute information. | 07-07-2011 |
20120105613 | ROBUST VIDEO-BASED HANDWRITING AND GESTURE RECOGNITION FOR IN-CAR APPLICATIONS - A method of receiving input from a user includes sensing a first trajectory of a center of mass of a hand of the user during a gesture made by the hand. A second trajectory of a finger tip of the hand of the user during the gesture made by the hand is also sensed. An alphanumeric character represented by the gesture made by the hand is determined dependent upon both the first trajectory and the second trajectory. | 05-03-2012 |
20130024113 | Selecting and Controlling the Density of Objects Rendered in Two-Dimensional and Three-Dimensional Navigation Maps - A method of displaying an electronic map includes receiving map data associated with a plurality of objects that are disposed within a geographic area. The map data is analyzed to thereby determine a state or value of a metric associated with one of the objects. The associated object is rendered in a low density or high density within the map depending upon the state or value of the metric. | 01-24-2013 |
20130317738 | STYLIZED PROCEDURAL MODELING FOR 3D NAVIGATION - A method of displaying a navigation map includes determining a route of a vehicle. A two-dimensional footprint of a building disposed within a geographic area is received within the vehicle. The geographic area includes the route of the vehicle. Attribute information associated with the building is received. The attribute information is received within the vehicle. A visual representation of the building is rendered based upon the two-dimensional footprint and the attribute information. | 11-28-2013 |
20140267229 | System And Method For Classification Of Three-Dimensional Models In A Virtual Environment - A method for classification of three-dimensional structures in a virtual environment includes identifying a plurality of polygons in a structure located in a virtual environment, identifying a plurality of surface normals, each surface normal corresponding to one polygon in the plurality of polygons that are in the structure, identifying a variance of a distribution of the plurality of surface normals, generating a first classification for the structure in response to the variance being less than a predetermined threshold, and generating a graphical display of the structure with at least one visual aspect of the structure being modified with reference to the first classification. | 09-18-2014 |
20140267248 | System And Method For Generation Of Shadow Effects In Three-Dimensional Graphics - Methods for generating ground shadow and lighting effects for three-dimensional models include identifying polygon data for a three-dimensional model, generating a convex polygon around a base of the model, generating hard and soft shadow meshes in and around the base of the model, and rendering the model with the shadow meshes with a display device. Methods for generating wall shadows and lighting effects for the three dimensional models further include identifying an orientation and height of a polygon in the model that extends from a ground surface in a virtual environment, and rendering the model with a lighting texture applied to either the full polygon if the polygon height is less than a threshold height or to only a portion of the polygon below the threshold height if the polygon exceeds the threshold height. | 09-18-2014 |
20140267271 | System And Method For Remote Generation Of Indirect Illumination Sources In Three-Dimensional Graphics - A method for generating three-dimensional graphics includes generating a virtual environment in a server including a first object, second object and a direct illumination source. The method includes generating a virtual point light (VPL) in the virtual environment at an intersection between a ray from the direct illumination source and the first object, and sending data corresponding to the VPL to a client computing device through a data network. The method includes generating an illumination of the second object in the virtual environment with the VPL received from the server, and displaying the illuminated second object. | 09-18-2014 |
20140267282 | System And Method For Context Dependent Level Of Detail Adjustment For Navigation Maps And Systems - A method for displaying visual information in a navigation system includes displaying a map of a geographic region including a first plurality of map features where each map feature in the first plurality of map features having an associated priority level that is below a predetermined priority level is displayed with a reduced level of detail. The method further includes identifying a second threshold in response to receiving an input signal from an input device and generating a second display of the map, the second display of the map including a modified visual depiction for at least one map feature in the first plurality of map features. | 09-18-2014 |
20140267346 | System and Method for Display of a Repeating Texture Stored in a Texture Atlas - In one embodiment, a method for generating textured graphics includes identifying border colors of pixels around two texture images and generating arrangements of border texels from the border colors that are positioned next to the two images in a texture atlas. The method includes generating mip-maps of the texture atlas with texels in the jump level assigned with the border color of the corresponding textures in the full-resolution texture atlas instead of the averaged color of the textures that would be assigned using a traditional mip-map process. The method includes storing the texture atlas including the two texture images and the border texels in a memory for use in generating repeated textures on an object in a virtual environment using at least one of the texture images with a mip-map without seam artifacts between the repeated textures. | 09-18-2014 |
20140277939 | Time and Environment Aware Graphical Displays for Driver Information and Driver Assistance Systems - A graphics display system for driver information and driver assistance applications generates controllable and dynamic graphical effects in conjunction with 3D visualization of maps. The system generates a display of a map in a 3D virtual environment that responds to the environment changes in a dynamic and visually intuitive manner for a vehicle operator. The system processes environment information, including lighting condition, weather condition, and other data acquired from different sensors in the vehicle such as cameras and lighting sensors, or through networked information services. The graphics display can be integrated with different driver information and driver assistance system embodiments including mobile platforms, in-vehicle information systems, web platforms, and PC systems. | 09-18-2014 |
20140278065 | System and Method for Distortion Correction in Three-Dimensional Environment Visualization - A method for graphics in a three-dimensional virtual environment corresponding to a physical environment around a vehicle includes photographs in a plurality of directions extending outward from the vehicle, generating sensor data corresponding to a relative distance from the vehicle and a direction from the vehicle of an object in the physical environment, generating a default three-dimensional projection surface centered around a virtual representation of the vehicle in a virtual environment, deforming the three-dimensional projection surface at relative locations and distances corresponding to the sensor data, projecting the plurality of photographs onto the deformed three-dimensional projection surface, and displaying graphics corresponding to the deformed three-dimensional projection surface with the plurality of projected photographs with a display device. | 09-18-2014 |
20160061622 | Occlusion-Reduced 3D Routing for 3D City Maps - In one embodiment, a method for rendering a route in a 3D virtual environment includes generating with a processor a 3D virtual environment including a plurality of 3D objects, the 3D virtual environment corresponding to a physical region, identifying with the processor a route for navigation through the 3D virtual environment corresponding to a route of travel through the physical region, generating with the processor and a display device a graphical rendering of the 3D virtual environment and the route with a height of the route being increased in regions of the 3D virtual environment where one or more of the plurality of 3D objects occludes a view of route, rendering of the route with partial transparency to provide visibility of objects occluded by the route and/or with navigation information, e.g. animated direction arrow, street names. | 03-03-2016 |
20160063757 | System and Method for Remote Shadow Rendering in a 3D Virtual Environment - A method for rendering shadows in a 3D virtual environment includes generating a depth rasterization map corresponding to a plurality of objects in a three-dimensional virtual environment and a shadow interval map with reference to the depth map and a predetermined path of a light source in the environment that casts light onto at least one object in the plurality of objects that generates a shadow in the three-dimensional virtual environment with a server computing device. The method includes transmitting the shadow interval map from the server to a client and generating, with a processor in the client, a graphical depiction of the virtual environment including at least one shadow generated with reference to the shadow interval map, the at least one shadow corresponding to the light source and the plurality of objects in the virtual environment. | 03-03-2016 |
Patent application number | Description | Published |
20130296225 | Microcrystalline Y Receptor Agonists - The disclosure provides microcrystals of Y receptor agonists; microcrystalline pellets of Y receptor agonists, and microcrystalline suspensions of Y receptor agonists. Pharmaceutical compositions containing these microcrystals, microcrystalline pellets, and microcrystalline suspensions have prolonged pharmacokinetic profiles making them useful for once daily or once weekly administration. | 11-07-2013 |
20150133373 | TRANSMUCOSAL DELIVERY OF ENGINEERED POLYPEPTIDES - Formulations are provided that comprise compounds having inter alia good duration of action, high potency and/or convenient dosing regimens, and a permeation enhancer for transmucosal administration. The compounds are engineered polypeptides which incorporate an albumin binding domain in combination with one or more biologically active polypeptides. The pharmaceutical compositions provided are suitable for methods of treatment for diseases and disorders including obesity and overweight, diabetes, dyslipidemia, hyperlipidemia, Alzheimer's disease, fatty liver disease, short bowel syndrome, Parkinson's disease, cardiovascular disease, and other and disorders of the central nervous system. | 05-14-2015 |
20150174209 | INSULIN-PRAMLINTIDE COMPOSITIONS AND METHODS FOR MAKING AND USING THEM - In alternative embodiments, the invention provides formulations, pharmaceutical compositions, devices and other products of manufacture comprising a therapeutically effective mixture of an insulin and a pramlintide, and methods for making and using them. For example, methods and compositions of the invention are used in the treatment or amelioration of a diabetes, a dementia or Alzheimer's disease, any abnormality of blood glucose control, an inability to control blood glucose, an elevation of fasting glucose or Impaired Fasting Glucose (IFG), an abnormality of tolerance to a glucose load or Impaired Glucose Tolerance (IGT), a hyperglycemia induced by an illness, a trauma, a medication administration or a form of metabolic, psychological or physical stress, or a hyperglycemia induced by steroids (steroid-induced diabetes), a latent autoimmune diabetes in adults (LADA), a postprandial or reactive Hypoglycemia or an insulin resistance, a PolyCystic Ovary Syndrome (PCOS), a ketoacidosis, a gestational diabetes, a hyperkalemia, a cancer or cachexia, a beta blocker overdose, or a jaundice. In alternative embodiments, the invention provides insulin pumps, devices, subcutaneous insulin infusion therapy devices, continuous subcutaneous insulin infusion therapy devices, infusion therapy devices, reservoirs, ampoules, vials, syringes, cartridges, disposable pen or jet injectors, prefilled pens or syringes or cartridges, cartridge or disposable pen or jet injectors, two chambered or multi-chambered pumps, syringes, cartridges or pens or jet injectors, or an artificial pancreas, comprising a formulation having an insulin:pramlintide ratio of the invention. | 06-25-2015 |
Patent application number | Description | Published |
20090294664 | ELECTRON BEAM APPARATUS - The present invention includes an electron beam device for examining defects on semiconductor devices. The device includes an electron source for generating a primary electron beam, wherein the total acceleration potential is divided and is provided across the ground potential. Also included is at least one condenser lens for pre-focusing the primary electron beam, an aperture for confining the primary electron beam to ameliorate electron-electron interaction, wherein the aperture is positioned right underneath the last condenser lens, and a SORIL objective lens system for forming immersion magnetic field and electrostatic field to focus the primary beam onto the specimen in the electron beam path. A pair of grounding rings for providing virtual ground voltage potential to those components within the electron beam apparatus installed below a source anode and above a last polepiece of the SORIL objective lens. | 12-03-2009 |
20100102227 | ELECTRON BEAM APPARATUS - The present invention relates to a charged particle beam apparatus which employs a scanning electron microscope for sample inspection and defect review. | 04-29-2010 |
20100150429 | E-BEAM DEFECT REVIEW SYSTEM - The present invention relates to a defect review system, and/or particularly, to an apparatus and method of defect review sampling, review method and classification on a semiconductor wafer or a pattern lithography reticle during integrated circuit fabrication. These objects are achieved in comparing a reviewed image with a reference image pick-up through a smart sampling filter. A clustering computer system base on high speed network will provide data cache and save operation time and memory. A smart review sampling filter automatically relocate abnormal pattern or defects and classify the device location extracted from design database and/or from golden die image on the same substrate. The column of the present defect review system is comprised of the modified SORIL type objective lens. This column provides solution of improving throughput during sample review, material identification better image quality, and topography image of defect. One embodiment of the present invent adopts an optical auto focusing system to compromise micro height variation due wafer surface topography. And another embodiment adopts surface charge control system to regulate the charge accumulation due to electron irradiation during the review process. | 06-17-2010 |
20110139996 | MULTI-AXIS MAGNETIC LENS - The present invention relates to a multi-axis magnetic lens for a charged particle beam system. The apparatus eliminates the undesired non-axisymmetric transverse magnetic field components from the magnetic field generated by a common excitation coil and leaves the desired axisymmetric field for focusing each particle beam employed within the system. | 06-16-2011 |
20120145898 | PARTICLE DETECTION SYSTEM - This invention provides a design to process a large range of detection beam current at low noise with a single detector. With such a design, the detection system can generate up to 10 | 06-14-2012 |
20120145900 | APPARATUS OF PLURAL CHARGED PARTICLE BEAMS WITH MULTI-AXIS MAGNETIC LENS - An apparatus basically uses a simple and compact multi-axis magnetic lens to focus each of a plurality of charged particle beams on sample surface at the same time. In each sub-lens module of the multi-axis magnetic lens, two magnetic rings are respectively inserted into upper and lower holes with non-magnetic radial gap. Each gap size is small enough to keep a sufficient magnetic coupling and large enough to get a sufficient axial symmetry of magnetic scale potential distribution in the space near to its optical axis. This method eliminates the non-axisymmetric transverse field in each sub-lens and the round lens field difference among all sub-lenses at the same time; both exist inherently in a conventional multi-axis magnetic lens. In the apparatus, some additional magnetic shielding measures such as magnetic shielding tubes, plates and house are used to eliminate the non-axisymmetric transverse field on the charged particle path from each charged particle source to the entrance of each sub-lens and from the exit of each sub-lens to the sample surface. | 06-14-2012 |
20120145917 | APPARATUS OF PLURAL CHARGED PARTICLE BEAMS WITH MULTI-AXIS MAGNETIC LENS - An apparatus basically uses a simple and compact multi-axis magnetic lens to focus each of a plurality of charged particle beams on sample surface at the same time. In each sub-lens module of the multi-axis magnetic lens, two magnetic rings are respectively inserted into upper and lower holes with non-magnetic radial gap. Each gap size is small enough to keep a sufficient magnetic coupling and large enough to get a sufficient axial symmetry of magnetic scale potential distribution in the space near to its optical axis. This method eliminates the non-axisymmetric transverse field in each sub-lens and the round lens field difference among all sub-lenses at the same time; both exist inherently in a conventional multi-axis magnetic lens. In the apparatus, some additional magnetic shielding measures such as magnetic shielding tubes, plates and house are used to eliminate the non-axisymmetric transverse field on the charged particle path from each charged particle source to the entrance of each sub-lens and from the exit of each sub-lens to the sample surface. | 06-14-2012 |
20120318978 | Monochromator for Charged Particle Beam Apparatus - The monochromator for reducing energy spread of a primary charged particle beam in charged particle apparatus comprises a beam adjustment element, two Wien-filter type dispersion units and an energy-limit aperture. In the monochromator, a dual proportional-symmetry in deflection dispersion and fundamental trajectory along a straight optical axis is formed, which not only fundamentally avoids incurring off-axis aberrations that actually can not be compensated but also ensures the exit beam have a virtual crossover which is stigmatic, dispersion-free and inside the monochromator. The present invention also provides two ways to build a monochromator into a SEM, in which one is to locate a monochromator between the electron source and the condenser, and another is to locate a monochromator between the beam-limit aperture and the objective. The former provides an additional energy-angle depending filtering, and obtains a smaller effective energy spread. | 12-20-2012 |
20130112889 | WIEN FILTER - This invention provides a multi-pole type Wien filter, which acts more purely approaching its fundamentally expected performance. A 12-electrode electric device acts as an electric deflector,or acts as an electric deflector and an electric stigmator together. A cylindrical 4-coil magnetic device with a magnetic core acts as a magnetic deflector. Both can produce a dipole field while only incurring a negligibly-small 3rd order field harmonic. The magnetic core enhances the strength and more preciously regulates the distribution of the magnetic field originally generated by the coils. Then two ways to construct a Wien filter are proposed. One way is based on both of the foregoing electric and magnetic devices, and the other way is based on the foregoing electric device and a conventional magnetic deflector. The astigmatism in each of such Wien filters can be compensated by the electric stigmator of the electric device. | 05-09-2013 |
20130153782 | Multi-axis Magnetic Lens for Focusing a Plurality of Charged Particle Beams - The present invention provides two ways to form a special permeability-discontinuity unit inside every sub-lens of a multi-axis magnetic lens, which either has a simpler configuration or has more flexibility in manufacturing such as material selection and mechanical structure. Accordingly several types of multi-axis magnetic lens are proposed for various applications. One type is for general application such as a multi-axis magnetic condenser lens or a multi-axis magnetic transfer lens, another type is a multi-axis magnetic non-immersion objective which can require a lower magnetomotive force, and one more type is a multi-axis magnetic immersion objective lens which can generate smaller aberrations. Due to using permeability-discontinuity units, every multi-axis magnetic lens in this invention can also be electrically excited to function as a multi-axis electromagnetic compound lens so as to further reduce aberrations thereof and/or realize electron beam retarding for low-voltage irradiation on specimen. | 06-20-2013 |
20130181138 | Multi-axis Magnetic Lens for Focusing a Plurality of Charged Particle Beams - A cellular-type PD unit is proposed and a plurality of the cellular-type PD units is used in pairs in a multi-axis magnetic lens for focusing a plurality of charged beams. First type PD units or second type PD units (called as hybrid PD unit as well) can be applied to cellular-type PD units to flexibly construct sub-lenses. Furthermore, magnetic shielding plates with a plurality of through openings can be placed above and/or below the multi-axis magnetic lens to make magnetic flux leaking out of the multi-axis magnetic lens vanish away rapidly outside the magnetic shielding plates. | 07-18-2013 |
20130248730 | Multi-axis Magnetic Lens for Focusing a Plurality of Charged Particle Beams - The present invention provides two ways to form a special permeability discontinuity unit inside every sub-lens of a multi-axis magnetic lens, which either has a simpler configuration or has more flexibility in manufacturing such as material selection and mechanical structure. Accordingly several types of multi-axis magnetic lens are proposed for various applications. One type is for general application such as a multi-axis magnetic condenser lens or a multi-axis magnetic transfer lens, another type is a multi-axis magnetic non-immersion objective which can require a lower magnetomotive force, and one more type is a multi-axis magnetic immersion objective lens which can generate smaller aberrations. Due to using permeability-discontinuity units, every multi-axis magnetic lens in this invention can also be electrically excited to function as a multi-axis electromagnetic compound lens so as to further reduce aberrations thereof and/or realize electron beam retarding for low-voltage irradiation on specimen. | 09-26-2013 |
20130277554 | Charged Particle Beam Apparatus - The present invention provides a charged particle beam apparatus which employs LVSEM to inspect sample surface with a throughput much higher than the prior art. The high throughput is realized by providing a probe current and a FOV both several times of those of the prior art. Accordingly several means are proposed to avoid obvious degradation of image resolution due to the increases in Coulomb effect and geometric aberrations, and increase efficiency and uniformity of secondary charged particle collection. | 10-24-2013 |
20140151554 | System and Method for Controlling Charge-up in an Electron Beam Apparatus - The present invention provides means and corresponding embodiments to control charge-up in an electron beam apparatus, which can eliminate the positive charges soon after being generated on the sample surface within a frame cycle of imaging scanning. The means are to let some or all of secondary electrons emitted from the sample surface return back to neutralize positive charges built up thereon so as to reach a charge balance within a limited time period. The embodiments use control electrodes to generate retarding fields to reflect some of secondary electrons with low kinetic energies back to the sample surface. | 06-05-2014 |
20140284476 | Energy Filter for Charged Particle Beam Apparatus - This invention provides a method for improving performance of a reflective type energy filter for a charged particle beam, which employs a beam-adjusting lens on an entrance side of a potential barrier of the energy filter to make the charged particle beam become a substantially parallel beam to be incident onto the potential barrier. The method makes the energy filter have both a fine energy-discrimination power over a large emission angle spread and a high uniformity of energy-discrimination powers over a large FOV. A LVSEM using this method in the energy filter can obviously improve image contrast. The invention also provides multiple energy-discrimination detection devices formed by using the advantages of the method. | 09-25-2014 |
20140291510 | Charged Particle Beam Apparatus - The present invention provides apparatuses to inspect small particles on the surface of a sample such as wafer and mask. The apparatuses provide both high detection efficiency and high throughput by forming Dark-field BSE images. The apparatuses can additionally inspect physical and electrical defects on the sample surface by form SE images and Bright-field BSE images simultaneously. The apparatuses can be designed to do single-beam or even multiple single-beam inspection for achieving a high throughput. | 10-02-2014 |
20150060662 | APPARATUS OF PLURAL CHARGED PARTICLE BEAMS WITH MULTI-AXIS MAGNETIC LENS - An apparatus of plural charged particle beams with multi-axis magnetic lens is provided to perform multi-functions of observing a specimen surface, such as high-throughput inspection and high-resolution review of interested features thereof and charge-up control for enhancing image contrast and image resolution. In the apparatus, two or more sub-columns are formed and each of the sub-columns performs one of the multi-functions. Basically the sub-columns take normal illumination to get high image resolutions, but one or more may take oblique illuminations to get high image contrasts. | 03-05-2015 |
20150060665 | System and Method for Controlling Charge-up in an Electron Beam Apparatus - The present invention provides means and corresponding embodiments to control charge-up in an electron beam apparatus, which can eliminate the positive charges soon after being generated on the sample surface within a frame cycle of imaging scanning. The means are to let some or all of secondary electrons emitted from the sample surface return back to neutralize positive charges built up thereon so as to reach a charge balance within a limited time period. The embodiments use control electrodes to generate retarding fields to reflect some of secondary electrons with low kinetic energies back to the sample surface. | 03-05-2015 |
20150060670 | System and Method for Controlling Charge-up in an Electron Beam Apparatus - The present invention provides means and corresponding embodiments to control charge-up in an electron beam apparatus, which can eliminate the positive charges soon after being generated on the sample surface within a frame cycle of imaging scanning. The means are to let some or all of secondary electrons emitted from the sample surface return back to neutralize positive charges built up thereon so as to reach a charge balance within a limited time period. The embodiments use control electrodes to generate retarding fields to reflect some of secondary electrons with low kinetic energies back to the sample surface. | 03-05-2015 |
20150083912 | Charged Particle Beam Apparatus - The present invention provides apparatuses to inspect small particles on the surface of a sample such as wafer and mask. The apparatuses provide both high detection efficiency and high throughput by forming Dark-field BSE images. The apparatuses can additionally inspect physical and electrical defects on the sample surface by form SE images and Bright-field BSE images simultaneously. The apparatuses can be designed to do single-beam or even multiple single-beam inspection for achieving a high throughput. | 03-26-2015 |
20150144788 | Charged Particle Beam Apparatus - The present invention provides a dual-beam apparatus which employs the dark-field e-beam inspection method to inspect small particles on a surface of a sample such as wafer and mask with high throughput. The dual beam apparatus comprises two single-beam dark-field units placed in a same vacuum chamber and in two different orientations. The two single-beam dark-field units can perform the particle inspection separately or almost simultaneously by means of the alternately-scanning way. The invention also proposes a triple-beam apparatus for both inspecting and reviewing particles on a sample surface within the same vacuum chamber. The triple-beam apparatus comprises one foregoing dual-beam apparatus performing the particle inspection and one high-resolution SEM performing the particle review. | 05-28-2015 |
20150155133 | Charged Particle Beam Apparatus - The present invention provides apparatuses to inspect small particles on the surface of a sample such as wafer and mask. The apparatuses provide both high detection efficiency and high throughput by forming Dark-field BSE images. The apparatuses can additionally inspect physical and electrical defects on the sample surface by form SE images and Bright-field BSE images simultaneously. The apparatuses can be designed to do single-beam or even multiple single-beam inspection for achieving a high throughput. | 06-04-2015 |
20150179384 | Multi-axis Magnetic Lens for Focusing a Plurality of Charged Particle Beams - A multi-axis magnetic lens with stable performance in focusing a plurality of charged particle beams is provided. The multi-axis magnetic lens comprises a plurality of magnetic dub-lens modules. On the one hand, the multi-axis magnetic lens employs an annular permanent-magnet unit to provide a basic and stable magnetic flux to the plurality of magnetic sub-lens modules. One the other hand, the multi-axis magnetic lens uses a plurality of subsidiary coils to provide additional and adjustable magnetic flux to the plurality of magnetic sub-lens modules respectively. The invention also proposes a method to turn off or adjust the basic and stable magnetic flux for some applications. Hence, this invention will benefit the applications which need to execute in a long time period while keeping a high stabilization in performance. | 06-25-2015 |
20150248990 | Energy-discrimination detection device - This invention provides a method for improving performance of a reflective type energy filter for a charged particle beam, which employs a beam-adjusting lens on an entrance side of a potential barrier of the energy filter to make the charged particle beam become a substantially parallel beam to be incident onto the potential barrier. The method makes the energy filter have both a fine energy-discrimination power over a large emission angle spread and a high uniformity of energy-discrimination powers over a large FOV. A LVSEM using this method in the energy filter can obviously improve image contrast. The invention also provides multiple energy-discrimination detection devices formed by using the advantages of the method. | 09-03-2015 |
20150371820 | Charged Particle Beam Apparatus - The present invention provides apparatuses to inspect small particles on the surface of a sample such as wafer and mask. The apparatuses provide both high detection efficiency and high throughput by forming Dark-field BSE images. The apparatuses can additionally inspect physical and electrical defects on the sample surface by form SE images and Bright-field BSE images simultaneously. The apparatuses can be designed to do single-beam or even multiple single-beam inspection for achieving a high throughput. | 12-24-2015 |
20160035533 | Energy Filter for Charged Particle Beam Apparatus - This invention provides two methods for improving performance of an energy-discrimination detection device with an energy filter of reflective type for a charged particle beam. The first method employs a beam-adjusting means to improve the energy-discrimination power, and the second method uses an electron-multiplication means to enhance the image signal without noise raise. A LVSEM with such an improved energy-discrimination detection device can provide variant high-contrast images of interested features on a specimen surface for multiple application purposes. | 02-04-2016 |
20160064180 | Apparatus of Plural Charged Particle Beams with Multi-axis Magnetic Lenses - A new apparatus of plural charged particle beams with multi-axis magnetic lenses is provided, which comprises a plurality of sub-columns The apparatus employs two modified multi-axis magnetic lenses, and magnetic sub-lenses thereof therefore function as the objective lenses and the condenser lenses of all the sub-columns respectively. The plurality of sub-columns can perform the same function or different functions required for observing a surface of a specimen, such as high-throughput inspection and high-resolution review of interested features thereon. Accordingly, the apparatus can be used as a yield management tool in semiconductor manufacturing industry. | 03-03-2016 |
Patent application number | Description | Published |
20080205360 | Balancing clusters of a wireless mesh network - An apparatus and method of propagating a size of a cluster within a wireless mesh network is disclosed. The method includes a gateway within the cluster maintaining information of access nodes within the cluster. The gateway determines a cluster size based on the maintained information, and transmits routing packets that include the cluster size of the gateway. An apparatus and method of balancing clusters of a wireless mesh network is also disclosed. The method includes the gateway of each cluster originating beacons, wherein the beacons include a size of the cluster of the gateway. The access nodes of each cluster, re-broadcasts beacons received from the gateway of the cluster. A connecting access node selects which cluster to connect to at least in part based on the size of each of the clusters. | 08-28-2008 |
20080261535 | Detection of underperforming antennas of nodes of wireless networks - An apparatus and method of detecting underperforming antennas of a wireless node of a wireless network are disclosed. The method includes measuring a wireless link quality between a first antenna of the wireless node and a receiver, and measuring a wireless link quality between a second antenna of the wireless node and the receiver. A difference between the wireless link quality of the first antenna and the link quality of the second antenna is determined. The wireless node is identified as having an underperforming antenna, if the difference between the wireless link qualities between the first antenna and the second antenna is greater than a faulty antenna detection threshold. | 10-23-2008 |
20080267141 | Identification of long links within a wireless network - An apparatus and method of identifying long links within a wireless network is disclosed. The method includes identifying long links within a wireless network. The method includes a first node estimating a link quality of a wireless link between the first node and a second node of the wireless network. The first node uni-casts packets to the second node. The first node monitors a packet acknowledgment success rate. The first node identifies the wireless link to be a long link if the link quality is above a link threshold, and the packet acknowledgment success rate is below an acknowledgment threshold. | 10-30-2008 |
20100202397 | Wireless Routing Based On Data Packet Classfication - Apparatuses and methods of using multiple radios of a wireless access node of a wireless network are disclosed. One method includes selecting a 4.9 GHz radio exclusively for public safety data packets, selecting other radios for other types of data packets, and selecting other radios for public safety data packets depending upon specification by a network operator. | 08-12-2010 |
20140064142 | UPDATING MULTICAST GROUP INFORMATION OF A CLIENT DEVICE OF A WIRELESS MESH NETWORK - Systems, methods and apparatuses for updating multicast group information of a client device of a wireless mesh network are disclosed. One method includes an access node of the wireless mesh network determining multicast group information of the client device that is connected to the access node, and the access node providing routing updates to upstream access nodes and a first upstream gateway, wherein the multicast group information of the client device is included within the routing updates of the client device. | 03-06-2014 |
20140068750 | ESTABLISHING AN IPSEC (INTERNET PROTOCOL SECURITY) VPN (VIRTUAL PRIVATE NETWORK) TUNNEL - Systems, methods and apparatuses of establishing an IPsec (Internet Protocol Security) VPN (Virtual Private Network) tunnel are disclosed. One method includes receiving, by a wireless mesh network access point, a user configuration, wherein the user configuration includes a type of traffic, determining an internal interface of the wireless mesh network access node based on the type of traffic, dynamically determining a local endpoint address for the IPsec VPN tunnel based on the selected internal interface, and establishing the IPsec VPN tunnel through the selected internal interface of the wireless mesh network access node. | 03-06-2014 |
20150033325 | ESTABLISHING AN IPSEC (INTERNET PROTOCOL SECURITY) VPN (VIRTUAL PRIVATE NETWORK) TUNNEL AND ENCAPSULATING NON-IP PACKETS - Systems, methods and apparatuses of establishing an IPsec (Internet Protocol Security) VPN (Virtual Private Network) tunnel are disclosed. One method includes receiving, by a wireless mesh network access point, a user configuration, wherein the user configuration includes a type of traffic, determining an internal interface of the wireless mesh network access node based on the type of traffic, dynamically determining a local endpoint address for the IPsec VPN tunnel based on the selected internal interface, establishing the IPsec VPN tunnel through the selected internal interface of the wireless mesh network access node, and encapsulating non-IP packets of non-IP traffic within IP packets. | 01-29-2015 |
20150200735 | DISTRIBUTION OF BROADCAST TRAFFIC THROUGH A MESH NETWORK - Systems, methods and apparatuses for supporting broadcast traffic through a wireless mesh network are disclosed. One method includes obtaining broadcast listening information of a broadcast listening access node, wherein the broadcast listening information includes an identifier of the broadcast listening access node, and a broadcast identifier of the broadcast listening device. The method further includes obtaining broadcast sourcing information of a broadcast sourcing access node, wherein the broadcast sourcing information includes an identifier of the broadcast sourcing access node, and a broadcast identifier of the broadcast sourcing device. The method further includes providing broadcast listening information of the broadcast listening access node to the broadcast sourcing access node upon determining the broadcast identifier of the broadcast sourcing device matches the broadcast identifier of the broadcast listening device. | 07-16-2015 |
20150201312 | DISTRIBUTION OF MULTICAST TRAFFIC THROUGH A MESH NETWORK - Systems, methods and apparatuses for distributing multicast traffic through a wireless mesh network are disclosed. One apparatus includes an access node that includes one or more transceivers for communicating with other devices of a wireless mesh network, and a processor. The processor is operative to receive a unicast IP packet that includes a special destination IP address through at least one of the one or more transceivers, determine, based on the special destination IP address and a multicast group ID of a multicast distribution table, whether to forward the unicast IP packet to a downstream device, and route the unicast IP packet to the downstream device based on the determination. | 07-16-2015 |
20150201323 | ENCAPSULATING RECEIVED MULTICAST TRAFFIC IN UNICAST IP PACKETS TO SUPPORT DISTRIBUTION OF MULTICAST TRAFFIC THROUGH A MESH NETWORK - Systems, methods and apparatuses of supporting multicast traffic of a wireless mesh network are disclosed. One apparatus includes an access node that includes one or more transceivers for communicating with other devices of a wireless mesh network, and a processor. The processor is operative to receive multicast traffic from a multicast traffic source through the one or more transceivers, associate the multicast traffic with a multicast group ID, and encapsulate the received multicast traffic in unicast IP packets that include a special destination IP address associated with the multicast group ID. | 07-16-2015 |
20150319629 | WIRELESS MESH ACCESS NODE NEIGHBORING CHANNEL QUALITY ESTIMATION - A controller of a wireless access node is operative to estimate an adjacent one of a plurality of wireless channels while the access node is communicating over a present one of the plurality of wireless channels, comprising the controller, determining a difference between a measured signal quality of a signal communicated over the present wireless channel and a measured signal quality of a signal communicated over the adjacent channel, estimate a difference between a packet success rate of the present channel and a packet success rate of the adjacent channel based on the determined difference, and estimating a packet success rate of the adjacent channel based on a packet success rate of the present channel and the estimated difference between the packet success rate of the present channel and the packet success rate of the adjacent channel. | 11-05-2015 |
Patent application number | Description | Published |
20140155412 | OLIGOMER-DIARYLPIPERAZINE CONJUGATES - The invention relates to (among other things) oligomer-diarylpiperazine conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over previously administered un-conjugated diarylpiperazine compounds. | 06-05-2014 |
20140323514 | MULTI-ARM POLYMER PRODRUGS - Provided herein are water-soluble prodrugs, compositions comprising such prodrugs, and related methods of making and administering the same. The prodrugs of the invention comprise a water-soluble polymer having three or more arms, at least three of which are typically covalently attached to an active agent, e.g., a small molecule. The conjugates of the invention provide an optimal balance of polymer size and structure for achieving improved drug loading, since the conjugates of the invention possess three or more active agents releasably attached to a multi-armed water-soluble polymer. The prodrugs of the invention are therapeutically effective, and exhibit improved properties in-vivo when compared to unmodified parent drug. | 10-30-2014 |
20140323529 | OLIGOMER-CALCIUM CHANNEL BLOCKER CONJUGATES - The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water soluble oligomer. | 10-30-2014 |
20140371168 | OLIGOMER-NUCLEOSIDE PHOSPHATE CONJUGATES - The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble, non-peptidic oligomer. The conjugates of the invention, when administered by any of a number administration routes, exhibits advantages over previously administered compounds. | 12-18-2014 |
20140378520 | OLIGOMER-NITROIMIDAZOLE ANTI-INFECTIVE CONJUGATES - The invention provides (among other things) small molecule drugs that are chemically modified by covalent attachment of a water-soluble oligomer. | 12-25-2014 |
20150335628 | OLIGOMER-CALCIUM CHANNEL BLOCKER CONJUGATES - The invention provides small molecule drugs that are chemically modified by covalent attachment of a water soluble oligomer. A conjugate of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from the characteristics of the small molecule drug not attached to the water soluble oligomer. | 11-26-2015 |
20150335640 | OLIGOMER-DIARYLPIPERAZINE CONJUGATES - The invention relates to (among other things) oligomer-diarylpiperazine conjugates and related compounds. A conjugate of the invention, when administered by any of a number of administration routes, exhibits advantages over previously administered un-conjugated diarylpiperazine compounds. | 11-26-2015 |