Patent application number | Description | Published |
20100292313 | COMPOSITIONS AND METHODS FOR TREATING ISCHEMIA AND ISCHEMIA-REPERFUSION INJURY - The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula II: | 11-18-2010 |
20110160294 | COMPOSITIONS AND METHODS FOR TREATING ISCHEMIA AND ISCHEMIA-REPERFUSION INJURY - The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula I: | 06-30-2011 |
20120135932 | Compositions And Methods For Treating Ischemia And Ischemia-Reperfusion Injury - The present invention relates, in some embodiments, to compositions comprising a substantially pure compound represented by Structural Formula (I) and methods of using such compounds to activate cytoprotective kinases. In additional embodiments, the invention relates to methods for treating an ischemia or an ischemia-reperfusion injury in a subject, comprising administering to the subject an effective amount of a compound of the invention (e.g., in multiple doses). The values and preferred values of the variables in Structural Formula (I) are defined herein. | 05-31-2012 |
20130237483 | Lipoyl Compounds And Their Use for Treating Ischemic Injury - The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (la) or compositions comprising compounds of Structural Formulas (I) and (la), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed. | 09-12-2013 |
20140274917 | Compositions and Methods for Treating Ischemia and Ischemia-Reperfusion Injury - The present invention relates to compositions comprising a substantially pure compound represented by Structural Formula I: | 09-18-2014 |
20150065564 | LIPOYL COMPOUNDS AND METHODS FOR TREATING ISCHEMIC INJURY - The present invention relates, in various embodiments, to a compound represented by Structural Formula (I), pharmaceutically acceptable salts or prodrugs thereof, and compositions comprising said compounds, or pharmaceutically acceptable salts or prodrugs thereof. Methods of using compounds of Structural Formulas (I) and (Ia) or compositions comprising compounds of Structural Formulas (I) and (Ia), or pharmaceutically acceptable salts or prodrugs thereof, to treat ischemia or ischemia-reperfusion injury are also disclosed. | 03-05-2015 |
20150329519 | Formulations Comprising Lipoyl Compounds - Provided herein are aqueous pharmaceutical formulations comprising monomeric lipoyl compounds, such as compounds of Structural Formula I: | 11-19-2015 |