Patent application number | Description | Published |
20130034533 | High Molecular Weight Derivatives of Vitamin K-Dependent Polypeptides - Modifications of vitamin K-dependent polypeptides that lead to enhanced protein function on a weight or molar basis and/or increase of protein lifetime in the circulation are described. Both objectives are important for using vitamin K-dependent polypeptides for pro- and anti-coagulation therapies, as well as for other uses in the circulation. | 02-07-2013 |
20130035394 | Calixarene-Based Peptide Conformation Mimetics, Methods of Use, and Methods of Making - A class of topomimetic calixarene-based peptide mimetics is described. Calixarene-based peptide mimetics have various biological activities such as, for example, bactericidal activity, antiangiogenic activity, and/or antitumor activity. Methods of use and methods of designing calixarene-based peptide mimetics are described. | 02-07-2013 |
20130062890 | CARBON DIOXIDE-BASED GEOTHERMAL ENERGY GENERATION SYSTEMS AND METHODS RELATED THERETO - Novel carbon dioxide-based geothermal energy generation systems, i.e., carbon plume geothermal (CPG) systems, and methods are provided. With the novel systems and methods described herein, geothermal energy can now be provided at lower temperatures and at locations other than hot, dry rock formations, without negatively impacting the surrounding area through use of large-scale hydrofracturing. Use of a carbon dioxide-based geothermal system further provides a means for sequestering and storing excess carbon dioxide, rather than having it released to the atmosphere. | 03-14-2013 |
20130068841 | SYMBOL-BASED DECODING OF OPTICAL CODES - Techniques and systems for decoding optical codes using symbol-based algorithms are described. In one example, a method includes acquiring a signal representative of light reflected from an optical code comprising one or more symbols of a finite set of symbols and applying a decoding model to the signal. The decoding model may relate measured signals to the finite set of symbols, such that each of the symbols of the finite set of symbols are associated with a respective encoded character of a finite set of encoded characters. The method may also include determining, by a processor, a sequence of one or more of the encoded characters based on the application of the decoding model to the signal. In this manner, the optical code may be decoded by directly fitting an acquired signal from the optical code to possible symbols within the optical code and the associated encoded characters. | 03-21-2013 |
20130090692 | INTRAOPERATIVE SPINAL STABILIZATION - A number of spinal stabilization devices are disclosed for aligning and fixing vertebrae during surgery, e.g. to facilitate accurate placement of pedicle screws. One stabilization device includes a pair of spiked rails biased to clamp shut and thereby passively engage a number of vertebrae. Another stabilization device includes a tie-rod that connects two or more fiducial markers, each of which is connected to a vertebra, to stabilize the vertebrae including and between each vertebra to which the markers are attached. | 04-11-2013 |
20130090698 | STRIPPED PEDICLE SCREW DRIVER BIT - A pedicle screw driver bit includes an elongated shank and a head. The shank includes a plurality of threads. The head is connected to one end of and configured to rotate relative to the shank. The head is configured to be received by a tulip connected to a pedicle screw. The threads of the shank are configured to engage a plurality of threads of the tulip such that when the shank is rotated the tulip is drawn into engagement with the head such that the shank, the head, the tulip, and the pedicle screw are substantially prevented from rotating relative to one another. | 04-11-2013 |
20130096413 | OPTICAL ULTRASOUND TRANSDUCER - In general, this disclosure describes various optical ultrasound transducers and methods of producing such. As one example, an optical ultrasound transducer comprises an optical fiber and a polymer layer formed on the optical fiber to receive light from the optical fiber. The polymer layer may absorb light of a first wavelength and be substantially transparent to light of a second wavelength. In response to the light of the first wavelength, the polymer layer may generate an acoustic tone. The optical ultrasound transducer may further include an optical detector formed on the polymer layer, the optical detector comprising an etalon structure having a first mirror layer and a second mirror layer separated by a compressible layer, wherein the compressible layer resonates in response to the light of the second wavelength passing through the polymer layer and is compressible in response to acoustic pressure from echoes of the acoustic tone. | 04-18-2013 |
20130112608 | METHODS, COMPOSITIONS AND DEVICES UTILIZING STRUCTURALLY STABLE CYANURIC ACID HYDROLASE - The present invention relates to stable cyanuric acid hydrolase enzymes, compositions, and devices for use in the treatment of a liquid, such as water. The present invention also relates to methods of using these enzymes, compositions and devices for the treatment of a liquid, such as water. | 05-09-2013 |
20130131659 | THERMOCHEMICAL ABLATION OF BODILY TISSUE - Thermochemical ablation techniques may provide ablation of bodily tissue using chemical reaction energy. | 05-23-2013 |
20130195752 | FUNCTIONALIZED NANOPARTICLES AND METHODS OF USE THEREOF - Certain embodiments of the present invention provide functionalized nanoparticles and methods of use thereof. Certain embodiments provide nanoparticles functionalized with streptokinase. Certain embodiments of the present invention provide methods for treating a pathological fibrin associated disorder (e.g., cancer) in an animal. | 08-01-2013 |
20130197241 | CYCLIZATION METHODS - The invention provides methods for cyclizing poly-yne compounds under mild conditions to provide cyclic compounds. | 08-01-2013 |
20130199093 | SOLAR GASIFIER - In various embodiments, the present invention provides a reaction chamber, including a catalyst, and a heating chamber configured to receive light. The heating chamber is positioned underneath at least a portion of the reaction chamber. | 08-08-2013 |
20130203978 | NUCLEOSIDES WITH ANTIVIRAL AND ANTICANCER ACTIVITY - The invention provides a compound of formula (I), wherein R1-R6 and X have any of the values described, as well as pharmaceutical compositions comprising such compounds and therapeutic methods comprising the administration of such compounds. | 08-08-2013 |