Reed, MD
Floyd Allan Reed, Greenbelt, MD US
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20110104689 | Single nucleotide polymorphisms and the identification of lactose intolerance - The present invention relates generally to methods, kits, genotyping and/or nucleic acid molecules associated with the identification of a predisposition for lactase persistence, lactase non-persistence, lactose tolerance and/or lactose intolerance. The methods of the present invention comprise in general determining the presence or absence of at least one variant allele having one or more single nucleotide polymorphisms within a gene associated with the expression of lactase-phlorizin hydrolase. The single nucleotide polymorphism is selected from the group consisting essentially of C-14010, G-13915 and G-13907, as measured from the start of the LCT gene. | 05-05-2011 |
Jennifer Reed, Clarksburg, MD US
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20100266594 | IL-9 IN FIBROTIC AND INFLAMMATORY DISEASE - The present invention encompasses methods of employing inhibitors of IL-9 in the treatment of fibrotic disorders, e.g., COPD and inflammatory bowel disease. | 10-21-2010 |
Jennifer L. Reed, Clarksburg, MD US
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20090162933 | EPHA2 AND HYPERPROLIFERATIVE CELL DISORDERS - The present invention relates to methods and compositions designed for the treatment, management, or prevention of a non-neoplastic hyperproliferative cell or excessive cell accumulation disorders, particularly those involving hyperproliferation of epithelial or endothelial cells. In one embodiment, the methods of the invention comprise the administration of an effective amount of one or more EphA2 agonistic agents that bind to EphA2 and increase EphA2 cytoplasmic tail phosphorylation and/or increase EphA2 autophosphorylation, in cells which EphA2 has been agonized. In another embodiment, the methods of the invention comprise the administration of an effective amount of one or more EphA2 agonistic agents that bind to EphA2 and reduce EphA2 activity (other than autophosphorylation). In another embodiment, the methods of the invention comprise administration of an effective amount of one or more EphA2 agonistic agents that bind to EphA2 and decrease a pathology-causing cell phenotype (e.g., a pathology-causing epithelial cell phenotype or a pathology-causing endothelial cell phenotype). In another embodiment, the methods of the invention comprise the administration of an effective amount of one or more EphA2 agonistic agents that are EphA2 antibodies that bind to EphA2 with a very low K | 06-25-2009 |
20110059100 | C/CLP Antagonists And Methods Of Use Thereof - The invention relates to the novel discovery that antagonizing a C/CLP can be useful for the treatment of diseases associated with the upregulation of one or more C/CLP such as Th2-driven and/or IL-13 mediated inflammatory diseases. Accordingly the present invention provides C/CLP antagonists and also provides compositions and methods for the prevention, management, treatment or amelioration of an inflammatory condition associated with the upregulation of a C/CLP or one or more symptoms thereof and/or the inhibition of IL-13 mediated inflammation. | 03-10-2011 |
Jennifer Lynne Reed, Clarksburg, MD US
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20080299134 | Recombinant Anti-Interleukin-9 Antibodies - The application describes neutralizing chimeric and humanized anti-human IL-9 antibodies, and the use thereof to identify neutralizing epitopes on human IL-9 and as medicaments to prevent and treat asthma, bronchial hyperresponsiveness, atopic allergy, and other related disorders. Particularly disclosed are recombinant antibodies derived from three murine anti-human IL-9 antibodies identified infra as MH9A3, MH9D1, and MH9L1. | 12-04-2008 |
20090047277 | RECOMBINANT IL-9 ANTIBODIES AND USES THEREOF - The present invention provides novel antibodies that immunospecifically bind to an IL-9 polypeptide and compositions comprising said antibodies. The present invention also provides methods and compositions preventing, treating, managing, and/or ameliorating diseases and disorders associated with aberrant expression and/or activity of IL 9 or IL-9 receptor or subunits thereof, autoimmune diseases, inflammatory diseases, proliferative diseases, and infections comprising administration of one or more antibodies thereof that immunospecifically bind to an IL-9 polypeptide. The invention also encompasses methods and compositions for diagnosing, monitoring, and prognosing these disorders. The present invention further relates to articles of manufacture and kits comprising antibodies that immunospecifically bind to an IL-9 polypeptide. | 02-19-2009 |
20090186038 | Methods of Preventing or Treating Respiratory Conditions - The present invention provides prophylactic an therapeutic protocols designed to prevent, manage, treat, or ameliorate a respiratory condition or one or more symptoms thereof. In particular, the present invention provides methods for preventing, managing, treating, or ameliorating a respiratory condition or one or symptoms caused by environmental factors or a respiratory infection. The present invention encompasses combination therapies, pharmaceutical compositions, articles of manufacture, and kits. | 07-23-2009 |
20120109097 | RECOMBINANT IL-9 ANTIBODIES AND USES THEREOF - The present invention provides novel antibodies that immunospecifically bind to an IL-9 polypeptide and compositions comprising said antibodies. The present invention also provides methods and compositions preventing, treating, managing, and/or ameliorating diseases and disorders associated with aberrant expression and/or activity of IL 9 or IL-9 receptor or subunits thereof, autoimmune diseases, inflammatory diseases, proliferative diseases, and infections comprising administration of one or more antibodies thereof that immunospecifically bind to an IL-9 polypeptide. The invention also encompasses methods and compositions for diagnosing, monitoring, and prognosing these disorders. The present invention further relates to articles of manufacture and kits comprising antibodies that immunospecifically bind to an IL-9 polypeptide. | 05-03-2012 |
20130273071 | Recombinant IL-9 Antibodies And Uses Thereof - The present invention provides novel antibodies that immunospecifically bind to an IL-9 polypeptide and compositions comprising said antibodies. The present invention also provides methods and compositions preventing, treating, managing, and/or ameliorating diseases and disorders associated with aberrant expression and/or activity of IL 9 or IL-9 receptor or subunits thereof, autoimmune diseases, inflammatory diseases, proliferative diseases, and infections comprising administration of one or more antibodies thereof that immunospecifically bind to an IL-9 polypeptide. The invention also encompasses methods and compositions for diagnosing, monitoring, and prognosing these disorders. The present invention further relates to articles of manufacture and kits comprising antibodies that immunospecifically bind to an IL-9 polypeptide. | 10-17-2013 |
John W. Reed, Ellicott City, MD US
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20100281638 | WHEEL WASHER - A wheel washer includes a frame. The wheel washer also includes a arm attachable to the frame, the arm being capable of movement with respect to the frame. The wheel washer further includes a brush attachable to the arm, the brush being capable of movement both in and out with respect to a surface of the frame and being capable of rotation in either a clockwise direction or a counterclockwise direction. The arm can be an articulated arm or a multi-axis arm. | 11-11-2010 |
Kenny Reed, Bethesda, MD US
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20160127342 | System and Method for Providing Security Monitoring - The present disclosure describes systems and methods for processing security sensor data that enhances the ability of a user to quickly and efficiently review portions of the sensor data streams. | 05-05-2016 |
Mason Reed, Perry Hall, MD US
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20150229269 | METHOD AND EQUIPMENT FOR TESTING PHOTOVOLTAIC ARRAYS - Devices and processes are provided configured to test electrical and physical function of photovoltaic modules at the location where the photovoltaic modules are installed and without having to disconnect the photovoltaic modules from their mechanical support or electrical circuits. | 08-13-2015 |
Mason Jacob Reed, Perry Hall, MD US
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20100021641 | SYSTEM AND METHOD FOR DISTRIBUTING A FLUIDIC MASS - Disclosed herein is a system for distributing a fluidic mass. The system includes, a receptacle, receptive of the fluidic mass to be distributed, an opening, fluidically connected to the receptacle, a surface in operable communication with the opening and receptive of a distribution of the fluidic mass from the receptacle such that a rate of the distribution of the fluidic mass is determined by a speed of the surface relative to the opening, and a substratum. The substratum is positioned below the surface and movable relative to the surface, and movement of the substratum relative to the surface controls a thickness of a base layer of the fluidic mass formed on the substratum. | 01-28-2010 |
Meredith L. Reed, Perry Hall, MD US
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20100187550 | LIGHT EMITTING DIODE - In a preferred embodiment, a light emitting device comprising: a polar template; a p-type layer grown on the polar template; the p-type layer having a first polarization vector; the first polarization vector having a first projection relative to a growth direction; an n-type layer grown on the p-type layer; the n-type layer having a second polarization vector; the second polarization vector having a second projection relative to said growth direction that is larger than the first projection of the first polarization vector for the p-type layer; the n-type layer and p-type layer forming an interface; whereby the first polarization vector in the p-layer and second polarization vector in the n-layer create a discontinuity at the interface resulting in a negative charge appearing at the interface. In another preferred embodiment, a light emitting device comprising: a polar template; a n-type layer grown on the template; the n-type layer having a first polarization vector; the first polarization vector having a first projection relative to a growth direction; an p-type layer grown on the n-type layer; the p-type layer having a second polarization vector; the second polarization vector having a second projection relative to said growth direction that is larger than the first projection of the first polarization vector for the p-type layer; the n-type layer and p-type layer forming an interface; whereby the first polarization vector in the p-layer and second polarization vector in the n-layer create a discontinuity at the interface resulting in a negative charge appearing at the interface. | 07-29-2010 |
Patrick W. Reed, Rockville, MD US
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20090280517 | METHODS OF DIAGNOSIS AND PROGNOSIS FOR A MUSCULAR DYSTROPHY - The invention relates to the treatment, diagnosis, and prognosis of a muscular dystrophy or myopathy. The present inventors have found that the quantity of mu-crystallin is increased in a muscular dystrophy. In particular, the inventors have found that mu-crystallin is increased in facioscapulohumeral muscular dystrophy (FSHD). Based on the inventors' findings, the invention provides a novel means for the treatment, diagnosis, and prognosis of a muscular dystrophy or myopathy. | 11-12-2009 |
Toby E. Reed, Columbia, MD US
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20100259607 | METHODS AND APPARATUS FOR IMAGING - Methods and apparatus for imaging according to various aspects of the present invention may generate an enhanced image of a target in an environment using image data from a sensor. The methods and apparatus may scale the image data to a higher resolution and register the image represented by the image data with other images of the same target. The enhanced image of the target is generated according to the registered images. | 10-14-2010 |