Rayner
Christopher Gary Rayner, Kaiapoi NZ
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20150014962 | SPLITBOARD BINDING APPARATUS - A boot attachment system is provided for a split board, wherein the boot attachment provides two alternative attachment configurations. The first configuration provides a ‘ride mode’ in which the rider's boots are attached across the two halves of the split board allowing the joined board halves to be used as a complete snowboard for riding downhill. The second configuration provides a ‘ski mode’ in which the rider's boots are attached one on each half of the split board. This system allows the halves of the board to be used in a similar manner to traditional skis. This system is particularly useful when travelling uphill or on terrain that is insufficiently steep for the board configuration to be useable. | 01-15-2015 |
Craig Rayner, South Yarra AU
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20140378376 | Dosage Regime for Apolipoprotein Formulations - An apolipoprotein formulation is provided at a fixed dosage that is efficacious in the prophylactic and/or therapeutic treatment of diseases or conditions including, but not limited to cardiovascular disease, acute coronary syndrome, atherosclerosis, unstable angina pectoris, and myocardial infarction. More particularly, the fixed dosage apolipoprotein formulation displays relatively reduced inter-patient variability compared to weight-adjusted dosages. Typically, the apolipoprotein formulation is a reconstituted high density lipoprotein formulation comprising ApoA1, one or more lipids such as phosphatidylcholine, sphingomyelin and/or phosphatidylglycerol and, optionally, a detergent such as cholate at a level that does not induce liver toxicity. | 12-25-2014 |
Danielle Rayner, Singapore SG
Katey Rayner, Ottawa CA
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20090054340 | Use of heat-shock protein 27 for cardiovascular disease prevention and treatment - A method of preventing or treating cardiovascular disease is provided. The method comprises administering heat shock protein 27 (HSP27), a co-factor, variant or analogue thereof. The cardiovascular disease can include atherosclerosis. A pharmaceutical composition comprising HSP27 for use in the prevention or treatment of cardiovascular disease is also provided. | 02-26-2009 |
20110124568 | USE OF HEAT-SHOCK PROTEIN 27 FOR CARDIOVASCULAR DISEASE PREVENTION AND TREATMENT - A method of reducing cholesterol in a subject is provided. The method may be used to decrease serum cholesterol and/or arterial wall cholesterol. The method comprises administering a therapeutically effective amount of heat shock protein 27 (HSP27), or a co-factor, variant or analogue thereof. The method may be used to treat, prevent or reverse cardiovascular disease (including atherosclerosis); to decrease atherosclerotic lesion formation or rupture; to decrease apoptosis within a plaque; to decrease macrophage accumulation; and/or to reverse the accumulation of atherosclerotic plaque mass in a subject. Kits and pharmaceutical compositions comprising HSP27 for preventing or treating of cardiovascular disease, such as atherosclerosis, are also provided. | 05-26-2011 |
Katey J. Rayner, Ottawa CA
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20140080899 | miR-33 Inhibitors and Uses Thereof to Decrease Inflammation - The inhibition of miRNA miR-33 is shown to promote the polarization of macrophages from an M1 to an M2 phenotype. MiR-33 inhibitors are therefore useful for treating inflammation in subjects. Endogenous microRNAs can be silenced using antagomirs. The miR-33 inhibitor is preferably an antagomir having a single-stranded nucleic acid sequence that is complementary to at least 12 contiguous nucleotides in miR-33 and therefore forms a duplex with miR-33 under physiological conditions. | 03-20-2014 |
Kevin Rayner, Cambridge CA
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20120225276 | METHODS AND APPARATUS FOR MAKING FOAM COMPOSITES REINFORCED WITH FIBERS AND FIBER PRE-FORMS HAVING PARTICLES THEREIN - According to one aspect, a method of forming foam composites. The method includes providing a plurality of microspheres in contact with a fiber pre-form having a plurality of fibers, inserting at least one penetrating element into the fiber pre-form, and repeatedly moving the at least one penetrating element within the fiber pre-form so as to encourage the plurality of microspheres to disperse within the fiber pre-form. The fiber pre-form with the microspheres dispersed therein is then heated, causing the microspheres to expand and fuse together to form the foam composite. | 09-06-2012 |
Marilyn Rayner, Lund SE
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20090264550 | MANUFACTURING METHOD OF A MEMBRANE AND A MEMBRANE THEREOF, FOR EMULSIFICATION - A manufacturing method of a membrane, a membrane obtained therefrom, and a use of said membrane for membrane emulsification. A desired shape of the membrane pores for spontaneous interfacial tension driven droplet formation is achieved by stretching the membrane material containing pores with a first shape, such that a second shape, i.e. the pores having an aspect ratio greater or equal to 3, is obtained. | 10-22-2009 |
20150125498 | NEW PARTICLE STABILIZED EMULSIONS AND FOAMS - The present invention relates to a particle stabilized emulsion or foam comprising at least two phases and solid particles, wherein said solid particles are starch granules and said starch granules or a portion thereof are situated at the interface between the two phases providing the particle stabilized emulsion or foam. The invention further relates to the use of said particle stabilized emulsion or foam for encapsulation of substances chosen from biopharmaceuticals, proteins, probiotics, living cells, enzymes and antibodies, sensitive food ingredients, vitamins, and lipids in food products, cosmetic products, skin creams, and pharmaceutical formulations. | 05-07-2015 |
Michael John Rayner, Vancouver CA
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20160085854 | Dynamic Natural Language Conversation - Technologies are described herein for providing dynamic natural language interactions between a user and a computing device. In one aspect, a computing device managing a conversation with a user is enhanced with the identification and management of one or more topics. Using techniques described herein, the computing device can focus on one or more topics, shift between topics and/or introduce new topics. Techniques disclosed herein may also manage and process interruptions that may be introduced during a conversation. Dynamic access of contextual information may assist in the generation of contextually-relevant statements, and the contextual information may be used to balance priorities between various topics. Each topic may also have an associated decay rate so that the lifespan of individual topics may track realistic scenarios. In addition, the priorities of individual topics may be dynamically adjusted so topics may track events created by a user and a computing device. | 03-24-2016 |
Terrence John Rayner, London CA
Timothy Edward Rayner, Netherby South Australia AU
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20100239556 | PROMOTING ECM PRODUCTION BY FIBROBLAST CELLS AND/OR PROMOTING MIGRATION OF FIBROBLAST CELLS IN A BIOLOGICAL SYSTEM - The present invention relates to a method of promoting production of one or more components of extracellular matrix by one or more fibroblast cells in a biological system and/or promoting migration of one or more fibroblast cells in a biological system. The method includes exposing one or more fibroblast cells in the biological system to an effective amount of an agent with peroxidase activity. | 09-23-2010 |
William Rayner, Annandale AU
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20120151780 | CUTTING APPARATUS - Cutting apparatus for cutting material, the apparatus comprising two blades arranged so that in use together they can effect a cutting operation in a cutting region therebetween, the blades being mounted relative to one another so that they are urged together in the cutting region as a result of a cutting force initiated by the cutting operation. In one embodiment at least one of the blades is mounted for pivotal movement about a pivot axis so that during the cutting operation the cutting or shearing force generated causes the blade to be pivotally urged towards the other blade. In another embodiment one blade is a rotatable cutter blade and the other blade is a further cutter blade which is adapted to cooperate together to perform the cutting operation in a cutting region, the further cutting blade being mounted so as to be urged towards the rotatable blade as a result of the cutting or shearing forces generated during the cutting operation. | 06-21-2012 |
20140116223 | CUTTING APPARATUS - In a first aspect there is provided a cutting apparatus for cutting material by a shearing action. The cutting apparatus comprises a first arm comprising a first cutting blade and a second arm comprising a second cutting blade. The second arm is operatively associated with the first arm and mounted relative to the first arm so as to define a cutting region between the first cutting blade and the second cutting blade in which cutting region a cutting operation of material is in use effected as a result of cooperation between the first cutting blade and the second cutting blade. At least one of the first and the second arm is operatively mounted so as to pivot about a pivot axis relative to the other arm. The second cutting blade is mounted to the second arm via a mounting region, the mounting region being laterally offset from the cutting region in a direction along the pivot axis such that cutting or shearing forces generated during a cutting operation cause the second cutting blade to be urged towards the first cutting blade. | 05-01-2014 |
William Rayner, Neutral Bay AU
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20090320664 | CUTTER DEVICE - A manually operable cutter device for cutting flexible sheet material, the cutter device comprising a cutter body which is movable over a work surface on which the flexible sheet being cut can rest. The device comprises a cutting blade assembly operatively mounted to the cutter body and including a rotatable cutter blade having a peripheral edge portion and a fixed cutter blade adapted to cooperate together to provide a cutting zone in which sheet material can be cut. The rotatable cutting blade is mounted for rotation about an axis which extends generally laterally with respect to a normal feed direction of the sheet material to the cutting zone and the direction of rotation of the peripheral edge portion through the cutting zone is in the normal feed direction. The tangential peripheral speed of the rotating cutter blade in the cutting zone is not less than the speed of the feed of sheet material to the cutting zone. | 12-31-2009 |