Patent application number | Description | Published |
20080220411 | NON-LINEAR ROTATION RATES OF REMOTELY DRIVEN PARTICLES AND USES THEREOF - The present invention relates to biological sensors. In particular, the present invention relates to the use of remotely driven nonlinear rotation of particles (e.g., magnetic particles) for detection of cells such as microorganisms (e.g., bacteria and viruses). The present invention further relates to the use of remotely driven nonlinear rotation of particles for measurement of physical properties of a solution (e.g., viscosity). | 09-11-2008 |
20080230717 | PHOTOACOUSTIC INDICATORS - A method of measuring fluorophore excited state lifetimes comprising initiating an excitation laser pulse at a dye to excite dye molecules of the dye from a ground state to an excited state and initiating a probing pulse at the dye molecules thereby generating a first set of photoacoustic waves at a first time delay resulting in a first intensity point. The process can be repeated, optionally introducing a second excitation laser pulse, to generate a second set of photoacoustic waves at a second time delay resulting in a second intensity point. The data can be analyzed to determine a slope between the first intensity point and the second intensity point. | 09-25-2008 |
20080297137 | UNIVERSAL, WIRELESS, NANO-OPTICAL VOLTMETERS - A universal, wireless, nano-optical voltmeter comprises an organic core having at least one voltage-sensitive dye and at least one polymeric shell substantially surrounding the organic core. The nano-optical voltmeter can detect electric fields in cells. The nano-optical voltmeter allows three-dimensional E field profiling throughout the entire volume of living cells. The nano-optical voltmeter may be calibrated externally and then applied for E field determinations inside any live cell or cellular compartment, with no further calibration steps. | 12-04-2008 |
20100098637 | DYE-LOADED NANOPARTICLE - The present invention generally relates to dye-loaded nanoparticles. In particular, the present invention provides methods for the staining and visualization of tumor and tumor boundaries using dye-loaded nanoparticles. | 04-22-2010 |
20110091373 | PAA NANOPARTICLES FOR ENHANCEMENT OF TUMOR IMAGING - A composition comprising PAA nanoparticles containing a post loaded tetrapyrollic photosensitizer and an imaging agent and methods for making and using same. | 04-21-2011 |
20120164680 | Asynchronous Magnetic Bead Rotation Sensing Systems and Methods - Described herein are various methods, devices and systems for performing asynchronous magnetic bead rotation (AMBR) to detect and monitor cellular growth and/or behavior. Cluster rotation of magnetic particles for AMBR is descried. In particular, described herein are systems for the parallel analysis of multiple wells of a sample plate. Also described herein are methods for controlling the illumination and imaging of rotating magnetic particles. | 06-28-2012 |
20130195758 | PAA NANOPLATFORMS CONTAINING FLUOROPHORES AND TARGETED MOIETIES COVALENTLY LINKED AND PHOTOSENSITIZER POST-LOADED - A PAA nanoparticle containing a covalently linked fluorescent dye and a post-loaded tetrapyrrolic photosensitizer. | 08-01-2013 |
20130202525 | MULTIFUNCTIONAL NANOPLATFORMS FOR FLUORESCENCE IMAGING AND PHOTODYNAMIC THERAPY DEVELOPED BY POST-LOADING PHOTOSENSITIZER AND FLUOROPHORE TO POLYACRYLAMIDE NANOPARTICLES - A composition comprising PAA nanoparticles containing a post loaded tetrapyrollic photosensitizer and a postloaded imaging agent and methods for making and using same. | 08-08-2013 |
20130202526 | PAA NANOPARTICLES FOR PET IMAGING AND PDT TREATMENT - PAA nanoparticles containing at least one tetrapyrrolic photosensitizer and at least one PET imaging agent. | 08-08-2013 |
20140248632 | Magnetically Induced Microspinning for Super-Detection and Super-Characterization of Biomarkers and Live Cells - Identification, quantification and characterization of biological micro- and nano-systems is enabled by magnetically spinning these natural, non-magnetic systems with the aid of induced magnetization. Biofriendly magnetic micro- and nano-labels enable magnetorotation in extremely weak electromagnetic fields. The spinning of these micromotors can be observed by a simple, CD-like, optical tracking system. The spinning frequency response enables real-time monitoring of single (cancer) cell morphology, with sub-microscopic resolution, yielding previously undeterminable information. Likewise, it enables super-low detection limits for any (cancer) biomarker. | 09-04-2014 |