Patent application number | Description | Published |
20130096659 | SYSTEMS AND METHODS FOR ANCHORING LEADS OF ELECTRICAL STIMULATION SYSTEMS - A lead anchor assembly includes a burr hole cover that defines a first lead aperture in a side exterior surface, a second lead aperture in a bottom exterior surface, and a fastener aperture. An anchoring unit is disposed in the burr hole cover and includes a fastener for anchoring a lead to the burr hole cover. A lead pathway is defined through the burr hole cover and the anchoring unit. The lead pathway extends from the first lead aperture to the second lead aperture and is configured to receive a lead. A fastener pathway is defined through both the burr hole cover and the anchoring unit and intersects the lead pathway at an anchoring location. The fastener pathway is configured for movement of the fastener along the fastener pathway to engage and disengage the lead when the lead extends along the lead pathway across the anchoring location. | 04-18-2013 |
20130268025 | Verifying Correct Operation of an Implantable Neurostimulator Device Using Current Distribution Circuitry - Monitoring circuitry for an implantable stimulator device is disclosed. A switching matrix allows current from a current source to be distributed to any of a plurality of electrodes. A voltage drop across the active switches in the switch matrix is monitored and is compared to an expected voltage based upon the amplitude of the current and the known on resistance of the switch. If the monitored and expected voltages differ significantly, then a failure condition can be inferred, and an appropriate action can be taken, such shutting down stimulation. Using the already-existing switches in the switching matrix in this fashion is beneficial because it allows the current through the electrodes to be monitored without providing additional structures in the therapeutic current path, which would increase complexity and add unwanted resistance. | 10-10-2013 |
20140094823 | MICRO-ELECTRODE RECORDING-GUIDED IMPLANTATION OF DIRECTIONAL LEADS - A method for implanting a lead within brain tissue of a patient, wherein the lead comprises a set of radially segmented electrodes on a distal end of the lead is provided. The method includes performing a plurality of microelectrode recordings through a respective plurality of recording tracts in the brain tissue; based on the microelectrode recordings, creating a three-dimensional map of a brain structure; positioning a graphical representation of the radially segmented electrodes over the map of the brain structure to create a graphical depiction of a desired depth and a desired radial orientation of the lead within the brain tissue; and implanting the lead in the brain tissue in accordance with the desired depth and desired radial orientation. A device for determining a radial orientation of the lead includes a radially directional ruler and an indicator for indicating which electrode is in contact with the ruler. | 04-03-2014 |
Patent application number | Description | Published |
20110173189 | GRAPH QUERYING, GRAPH MOTIF MINING AND THE DISCOVERY OF CLUSTERS - A method for analyzing, querying, and mining graph databases using subgraph and similarity querying. An index structure, known as a closure tree, is defined for topological summarization of a set of graphs. In addition, a significance model is created in which the graphs are transformed into histograms of primitive components. Finally, connected substructures or clusters, comprising paths or trees, are detected in networks found in the graph databases using a random walk technique and a repeated random walk technique. | 07-14-2011 |
20120259915 | METHOD AND SYSTEM FOR MAXIMIZING CONTENT SPREAD IN SOCIAL NETWORK - A method, a system and a computer program product for maximizing content spread in a social network are provided. Samples of edges are generated from an initial candidate set of edges. Each edge of the samples of edges has a probability value for content flow. Further, a subset of edges is determined from the samples of edges based on gain corresponding to each edge. Also, each node of the subset of edges is having at least one of less than ‘K’ or equal to ‘K’ incoming edges. Further, the probability of each edge, of the subset of edges, may be incremented. Furthermore, a final set of edges may be determined by ensuring ‘K’ incoming edges. The ‘K’ incoming edges may be ensured by removing one or more incoming edges when a number of the incoming edges for a node of the final set is greater than ‘K’ incoming edge. | 10-11-2012 |
20120290624 | DEFINING AND MINING A JOINT PHARMACOPHORIC SPACE THROUGH GEOMETRIC FEATURES - A technique for mining pharmacophore patterns including computer-implemented methods for generating a database of pharmacophores and computer-implemented methods for classifying a query molecule with the database of pharmacophores. Generation of the pharmacophore database includes methods of defining a Joint Pharmacophore Space (JPS) using the three-dimensional geometry of pharmacophoric features of all active molecules against multiple targets. | 11-15-2012 |