Randolph B.
Randolph B. Deprince, Raleigh, NC US
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20100310510 | N-TERMINALLY CHEMICALLY MODIFIED PROTEIN COMPOSITIONS AND METHODS - Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon. | 12-09-2010 |
20120296072 | N-TERMINALLY CHEMICALLY MODIFIED PROTEIN COMPOSITIONS AND METHODS - Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon. | 11-22-2012 |
20130189219 | N-TERMINALLY CHEMICALLY MODIFIED PROTEIN COMPOSITIONS AND METHODS - Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon. | 07-25-2013 |
Randolph B. Haagens, Bellevue, WA US
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20120239722 | READ-ONLY OPERATIONS PROCESSING IN A PAXOS REPLICATION SYSTEM - Embodiments are directed to processing read-only operations without storing the operations persistently, determining a processing order for read-only requests, and to directing read-only requests to nodes best able to handle the requests. In an embodiment, a quorum leader receives various read-only requests. The quorum leader controls process ordering for replicas in the leader's quorum. The quorum leader determines an appropriate order for processing the read-only operations, without clock-based synchronization. The quorum leader sends the read-only request to an appropriate replica in the quorum and executes the read-only request at the appropriate replica without storing the operation persistently. | 09-20-2012 |
20140181026 | READ-ONLY OPERATIONS PROCESSING IN A PAXOS REPLICATION SYSTEM - Embodiments are directed to processing read-only operations without storing the operations persistently, determining a processing order for read-only requests, and to directing read-only requests to nodes best able to handle the requests. In an embodiment, a quorum leader receives various read-only requests. The quorum leader controls process ordering for replicas in the leader's quorum. The quorum leader determines an appropriate order for processing the read-only operations, without clock-based synchronization. The quorum leader sends the read-only request to an appropriate replica in the quorum and executes the read-only request at the appropriate replica without storing the operation persistently. | 06-26-2014 |
Randolph B. Krafcik, Aurora, OH US
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20140303281 | HYBRID LATEX PARTICLES FOR SELF-STRATIFYING COATINGS - The present invention relates to coating compositions formed by combining two latex resins: a base latex resin and a stratifying latex resin. The stratifying latex resin comprises hybrid metal oxide latex particles wherein the hybrid particles are the polymerization reaction product of at least one or more copolymerizable monoethylenically unsaturated monomers, wherein the monoethylenically unsaturated monomers comprise at least one low surface energy driver monomer selected from the group consisting of (i) a fluorine containing monomer; and (ii) a silane-containing monomer; and wherein the polymerization reaction is in the presence of a metal oxide nanoparticle; and wherein the metal oxide nanoparticle is embedded within the hybrid particles. | 10-09-2014 |
Randolph B. Lipscher, Austin, TX US
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20130066648 | SYSTEMS AND METHODS FOR DISEASE MANAGEMENT ALGORITHM INTEGRATION - A system includes a disease management advisor system configured to receive a disease management algorithm from a disease management advisor, the disease management algorithm including a selection condition and a healthcare provider system response action; a healthcare provider system communicatively coupled to the disease management advisor system and to receive the disease management algorithm from the disease management advisor system; and a conversion module accessible to the healthcare provider system and to convert the disease management algorithm to a healthcare provider algorithm based on a controlled medical vocabulary, the healthcare provider system to implement the healthcare provider system response action in accordance with the healthcare provider algorithm. | 03-14-2013 |
Randolph B. Robert, Iii, Athens, OH US
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20140257036 | Method And Device For Detecting Thermal Effects Of Tissue Ablation On A Tissue Of A Patient - A method and device for detecting thermal effects of tissue ablation on a tissue of a patient includes an endoscope, a biopsy forceps, and an electrical measurement circuit. The method includes measuring a first value of an electrical property of the tissue and removing at least a portion of the tissue with the hot biopsy forceps. The method also includes measuring a second value of the electrical property of the remaining tissue. Accordingly, the electrical measurement circuit is configured to correlate the difference between the first and second values to a depth of ablation. | 09-11-2014 |