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Ramshaw

Bruce John Ramshaw, Columbia, MO US

Patent application numberDescriptionPublished
20100106233BIONANOCOMPOSITE FOR TISSUE REGENERATION AND SOFT TISSUE REPAIR - The present invention provides a bionanocomposite including a pre-selected decellularized tissue crosslinked with a pre-selected nanomaterial. Also provided is a process for fabricating the bionanocomposite. Additionally, applications for using the bionanocomposite as soft tissue repair materials or scaffolds for tissue engineering are described.04-29-2010

Clifford Ramshaw, San Rafael, CA US

Patent application numberDescriptionPublished
20120299914ACCELERATED SUBSURFACE SCATTERING DETERMINATION FOR RENDERING 3D OBJECTS - The present disclosure includes, among other things, systems, methods, and program products for estimating radiant exitance due to subsurface scattering. For example, one or more aspects of the subject matter described in this disclosure can be embodied in one or more methods that include distributing a plurality of sample points across the surface of a 3D object model to be rendered into a 2D image and determining a solid angle subtended by a first sample point and a second sample point relative to a region on the 3D object model. Depending on the determined solid angle relative to a threshold value, a previously determined subsurface scattering contribution for the region or a newly determined subsurface scattering contribution for the region may selectively be used for rendering a portion of the 2D image.11-29-2012

Heather Ramshaw, Napanee CA

Patent application numberDescriptionPublished
20100008902P450RAI-2 (P450 CYTOCHROME 26B), ENCODING NUCLEIC ACID MOLECULES AND METHODS AND USES THEREOF - The present invention provides a novel all-trans-RA inducible all-trans-RA metabolizing cytochrome P450, P450RAI-2, that is predominantly expressed in the brain, cerebellum in particular. It is also expressed in normal and tumour lung tissue and in breast cancer cells and may have a correlation with lung and breast cancer. Human P450RAI-2 show 42% amino acid identity to human P450RAI-1 and when transfected into COS-1 cells causes the rapid conversion of all-trans-RA into more polar metabolites including the inactive products 4-oxo-RA, 4-OH-RA and 18-OH-RA. P450RAI-2, as with P450RAI-1, is also inducible in certain cultured cell lines exposed to all-trans-RA. Methods for and uses of the new polynucleotide, polypeptide, fragments thereof and inhibitors thereof, include the treatment of dermatological disorders, cancer and certain brain disorders.01-14-2010

Patent applications by Heather Ramshaw, Napanee CA

Ian Allister Ramshaw, Duffy AU

Patent application numberDescriptionPublished
20120177668IMMUNOMODULATING COMPOSITIONS COMPRISING INTERLEUKIN 13 INHIBITORS AND USES THEREFOR - This invention relates generally to compositions and methods for modulating immune responses. More particularly, the present invention relates to the co-expression, co-location or co-presentation on host cells (e.g. antigen-presenting cells, leukocytes, etc) of an inhibitor of IL-13 function and an immune stimulator that stimulates an immune response to a target antigen in compositions and methods for stimulating protective or therapeutic immune responses to the target antigen. The compositions and methods of the present invention are particularly useful in the prophylaxis and/or treatment of a range of diseases or conditions including pathogenic infections and cancers.07-12-2012

John Ramshaw, Pascoe Vale AU

Patent application numberDescriptionPublished
20120116053EXPRESSION OF TRIPLE-HELICAL COLLAGEN-LIKE PRODUCTS IN E.COLI - Recombinant bacterial triple-helical collagen-like proteins comprising two or more repetitive sequences of Gly-Xaa-Yaa yielding high-stability polymeric constructs without the need for post-translational modifications and which may incorporate one or more functional domains of biological or structural importance. The polymers are capable of high-yield production for a variety of applications05-10-2012

John Alan Maurice Ramshaw, Pascoe Vale AU

Patent application numberDescriptionPublished
20090324675BIOOCOMPATIBLE POLYMER COMPOSITIONS - The present invention provides a biocompatible prepolymer comprising hydrophilic and hydrophobic segments, wherein the hydrophobic segments have at least one ethylenically unsaturated functional group and at least 5% of the segments have two or more ethylenically unsaturated functional groups and water. The invention further provides a biocompatible prepolymer composition comprising hydrophilic and hydrophobic prepolymers, wherein at least one of the hydrophobic prepolymers has at least one ethylenically unsaturated functional group and at least 5% of the prepolymers have two or more ethylenically unsaturated functional groups and water. The invention further provides use of the prepolymer or prepolymer compositions of the invention in biomedical applications such as tissue engineering, as bone substitutes or scaffolds, and in wound treatment.12-31-2009

John Alan Maurice Ramshaw, Victoria AU

Patent application numberDescriptionPublished
20090098177Methods and devices for tissue repair - Methods for treating diseased or damaged tissue in a subject are disclosed, involving administering to said subject at a site wherein diseased or damaged tissue occurs, cells of a type(s) normally found in healthy tissue corresponding to the diseased or damaged tissue, and/or suitable progenitor cells thereof, in association with bioresorbable beads or particles and optionally a gel and/or gel-forming substance. Where the cells an/or suitable progenitor cells thereof are chondrocytes, embryonic stem cells and/or bone marrow stromal cells, the methods of the invention are suitable for treating, for example, articular cartilage degeneration associated with primary osteoarthritis. Also disclosed is a device having tissue-like characteristics for treating diseased or damaged tissue in a subject, wherein the device comprises cells of a type(s) normally found in healthy tissue corresponding to the diseased or damaged tissue, and/or suitable progenitor cells thereof, in association with bioresorbable beads or particles and optionally a gel and/or gel-forming substance.04-16-2009
20090104593Preparation and Use of Basement Membrane Particles - A method for supporting the in vitro growth of one or more eukaryotic cell type(s), the method comprising; seeding cells of said cell type(s) onto particles comprising basement membrane or a basement membrane-like substrate, and culturing said seeded cells in vitro under conditions suitable for expansion of said seeded cells, wherein said particles are less than about 500 μm in size.04-23-2009
20110190813PHOTOACTIVATED CROSSLINKING OF A PROTEIN OR PEPTIDE - A method of crosslinking a protein or peptide for use as a biomaterial, the method comprising the step of irradiating a photoactivatable metal-ligand complex and an electron acceptor in the presence of the protein or peptide, thereby initiating a crosslinking reaction to form a 3-dimensional matrix of the biomaterial.08-04-2011

John A.m. Ramshaw, Victoria AU

Patent application numberDescriptionPublished
20090176971Method for Determining Thermal Stability of Collagen or Collagen-Like Peptide - The present invention is a method for determining the thermal stability of a collagen peptide, collagen-like peptide or triple-helix construct with the repeating peptide unit Gly-Xaa07-09-2009

Lyle H. Ramshaw, Palo Alto, CA US

Patent application numberDescriptionPublished
20110270671Predicting number of selections of advertisement using hierarchical Bayesian model - A predetermined distribution type of a number of selections of an advertisement within a predetermined time period for a predetermined phrase and having a predetermined advertisement location is specified. A parameterization of a mean of the predetermined distribution type is also specified. The mean is determined using a hierarchical Bayesian model, based on the predetermined distribution type, the parameterization, and historical data regarding a number of actual selections of the advertisement for each of a number of phrases similar to the predetermined phrase. The mean corresponds to an average number of selections of the advertisement within the predetermined time period for the predetermined phrase and having the predetermined advertisement location, as predicted by the model.11-03-2011
20110283283DETERMINING MULTIPROGRAMMING LEVELS - A method of managing the execution of a workload of transactions of different transaction types on a computer system. Each transaction type may have a different resource requirement. The method may include intermittently, during execution of the workload, determining the performance of each transaction type. A determination may be made of whether if there is an overloaded transaction type in which performance is degraded with an increase in the number of transactions of the transaction type. If there is an overloaded transaction type, the number of transactions of at least one transaction type may be changed.11-17-2011
20110283294DETERMINING MULTI-PROGRAMMING LEVEL USING DIMINISHING-INTERVAL SEARCH - A method of determining a multiprogramming level (MPL) for a first computer subsystem may be implemented on a second computer subsystem. The method may include selecting an initial MPL interval having endpoints that bound a local extremum of a computer-system operation variable that is a unimodal function of the MPL. For each interval having a length more than a threshold, operation-variable values for two intermediate MPLs in the interval may be determined. The interval may be diminished by the section of the interval between the one of the intermediate MPLs having an operation-variable value further from the extremum, and the interval endpoint adjacent to the one intermediate MPL. The operating MPL may be set equal to the other intermediate MPL when the interval has a length that is not more than the threshold.11-17-2011

Lyle Harold Ramshaw, Palo Alto, CA US

Patent application numberDescriptionPublished
20120110597DETERMINING MULTI-PROGRAMMING LEVELS - An embodiment includes determining user loads and control parameter values. The determining control parameter values are mapped to a performance metric using a function. A constant performance metric is determined where the value of the function calculated at each control parameter value is less than said constant performance metric. An isocontour is defined based on the constant performance metric for each user load. Finally an operating envelope is calculated by correlating the isocontours of multiple user loads.05-03-2012

Sylvain Ramshaw, Sugar Land, TX US

Patent application numberDescriptionPublished
20090316528JOB MONITORING METHODS AND APPARATUS FOR LOGGING-WHILE-DRILLING EQUIPMENT - Job monitoring methods and apparatus for logging-while-drilling equipment are disclosed. A disclosed example method includes obtaining a fluid associated with an underground geological formation, analyzing the fluid with one or more sensors to form respective ones of sensor outputs, identifying a downhole scenario associated with the fluid based on the sensor outputs, the identifying being performed while the sensors are within the underground geological formation, and selecting a telemetry frame type based on the identified downhole scenario.12-24-2009
20120152533Control of a Component of a Downhole Tool - An apparatus including a downhole tool for conveyance in a wellbore extending into a subterranean formation and method of use thereof. The downhole tool may include a turbo-alternator disposed in a passageway for drilling mud, and a controller to: track operating points of the turbo-alternator, determine from the operating points a flow rate of the drilling mud, and control a component of the downhole tool based on the flow rate.06-21-2012
20120166089Job Monitoring Methods and Apparatus for Logging-While-Drilling Equipment - Job monitoring methods and apparatus for logging-while-drilling equipment are disclosed. A disclosed example method includes obtaining a fluid associated with an underground geological formation, analyzing the fluid with one or more sensors to form respective ones of sensor outputs, identifying a downhole scenario associated with the fluid based on the sensor outputs, the identifying being performed while the sensors are within the underground geological formation, and selecting a telemetry frame type based on the identified downhole scenario.06-28-2012