Ramón
Ramón Arana Errasqui, Mexico MX
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20100330679 | DEVICE AND METHOD FOR MEASURING THE WATER ACTIVITY OF FOODS - Example embodiments relate a device for measuring the water activity of foods and method for obtaining a water activity measurement. The device includes a container housing the food sample, a disc of permeable material to support a reactive substance which in turn is used to record the water activity level of the food sample ( | 12-30-2010 |
Ramón Arana Errasqui, Mexico MX
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20100330679 | DEVICE AND METHOD FOR MEASURING THE WATER ACTIVITY OF FOODS - Example embodiments relate a device for measuring the water activity of foods and method for obtaining a water activity measurement. The device includes a container housing the food sample, a disc of permeable material to support a reactive substance which in turn is used to record the water activity level of the food sample ( | 12-30-2010 |
Ramón Artigas Puerto, San Cugat Del Valles ES
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20110294659 | PHOTOCATALYTIC MIXTURE FOR THE DEGRADATION OF NITROGEN OXIDES - A first aspect of the invention consists of a photocatalytic mixture designed to obtain degradation of nitrogen oxides through synergic combination of the two compounds: TiO | 12-01-2011 |
Ramón Artigas Puerto, Barcelona ES
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20120172222 | STRENGTHENING COMPOSITION REGULATING TRANSPIRATION AND PROTECTING LEAVES AND FRUIT, AND THE USE OF SAME - The invention relates to the field of agriculture and, in particular, to products for improving agricultural crop yields. More specifically, the present invention relates to a strengthening composition that regulates transpiration and protects leaves and fruits, said composition containing zeolite as a base, preferably zeolite 4A, and other additives which boost the activity thereof and facilitate the application of same in an aqueous suspension or dry. In addition, the invention relates to the different uses of said composition. | 07-05-2012 |
Ramón Berenguer Maimó, Barcelona ES
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20080242867 | ACETONE SOLVATE OF PHTHALOYL AMLODIPINE - An acetone solvate of phthaloyl amlodipine, as well as a process for its preparation including dissolving phthaloyl amlodipine in acetone and cooling the mixture. The present invention also comprises a method for the synthesis of amlodipine, its salts or solvates, which comprises the use of an acetone solvate of phthaloyl amlodipine. | 10-02-2008 |
20100004446 | Process for the Preparation of Abacavir - Process for removal of the amino protective group of a N-acylated [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl]methanol of formula (II) where R═H or a (C | 01-07-2010 |
20100041883 | Process for the preparation of abacavir - Process for the preparation of abacavir, or its salts or its solvates comprising the step of reacting a compound (IV) where R | 02-18-2010 |
20100298354 | Crystalline Form Of Abacavir That Is Essentially Free Of Solvent - Crystalline form of abacavir that is essentially free of solvent of formula (I), in particular crystalline Form I, and its preparation process which comprises the following steps: a) crystallizing abacavir from a solution of said compound in a (C | 11-25-2010 |
20120309976 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE - A preparation process of esomeprazole sodium substantially free of sulfone impurity including the steps of: a) combining either esomeprazole with a (C | 12-06-2012 |
20120316336 | 4-[-2-[[5-METHYL-1-(2-NAPHTALENYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE HYDROCHLORIDE POLYMORPHS AND SOLVATES - The present invention relates to polymorphs and solvates of the hydrochloride salt of 4-[2-[[5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine (P027), processes for their preparation, and to pharmaceutical compositions comprising them. | 12-13-2012 |
20130184472 | Process for the Preparation of 1-ARYL-PYRAZOL-3-ONE Intermediates Useful in the Synthesis of SIGMA Receptors Inhibitors - The invention relates to a process for preparing 1-aryl-pyrazol-3-one intermediates, tautomers, and salts thereof, to novel intermediates, and to the use of the intermediates in the preparation of sigma receptor inhibitors. | 07-18-2013 |
20130296558 | PREPARATION PROCESS OF AN ANTIVIRAL DRUG (ENTECAVIR) AND INTERMEDIATES THEREOF - It comprises a preparation process of entecavir comprising: submitting a (1S,3R)-3-(tert-butyldimethylsilyloxy)-1-(oxiran-2-yl)pent-4-yn-1-ol (VIII) to a double esterification and to a radicalary cyclization, yielding a compound of formula (V), where either a compound of formula (VIII) is submitted to a first esterification reaction, then to a catalytic radicalary cyclization using titanocene dichloride as catalyst in the presence of Mn/2,4,6-collidine HCl or Zn/2,4,6-collidine/trimethylsilyl chloride, and finally to a second esterification reaction or, alternatively, the compound of formula (VIII) is submitted first to a catalytic radicalary cyclization, and then to an esterification reaction. Entecavir can be obtained by submitting compound (V) to a desilylation reaction to remove the TBS group and then to a Mitsunobu coupling with 2-amino-6-chloroguanine, followed by hydrolysis. It also relates to some new intermediates of the process. | 11-07-2013 |
Ramón Berenguer Maimó, Barcelona ES
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20100004446 | Process for the Preparation of Abacavir - Process for removal of the amino protective group of a N-acylated [(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-cyclopent-2-enyl]methanol of formula (II) where R═H or a (C | 01-07-2010 |
20100041883 | Process for the preparation of abacavir - Process for the preparation of abacavir, or its salts or its solvates comprising the step of reacting a compound (IV) where R | 02-18-2010 |
20100298354 | Crystalline Form Of Abacavir That Is Essentially Free Of Solvent - Crystalline form of abacavir that is essentially free of solvent of formula (I), in particular crystalline Form I, and its preparation process which comprises the following steps: a) crystallizing abacavir from a solution of said compound in a (C | 11-25-2010 |
20120309976 | PREPARATION PROCESS OF THE SODIUM SALT OF ESOMEPRAZOLE - A preparation process of esomeprazole sodium substantially free of sulfone impurity including the steps of: a) combining either esomeprazole with a (C | 12-06-2012 |
20120316336 | 4-[-2-[[5-METHYL-1-(2-NAPHTALENYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE HYDROCHLORIDE POLYMORPHS AND SOLVATES - The present invention relates to polymorphs and solvates of the hydrochloride salt of 4-[2-[[5-methyl-1-(2-naphthalenyl)-1H-pyrazol-3-yl]oxy]ethyl]morpholine (P027), processes for their preparation, and to pharmaceutical compositions comprising them. | 12-13-2012 |
20130296558 | PREPARATION PROCESS OF AN ANTIVIRAL DRUG (ENTECAVIR) AND INTERMEDIATES THEREOF - It comprises a preparation process of entecavir comprising: submitting a (1S,3R)-3-(tert-butyldimethylsilyloxy)-1-(oxiran-2-yl)pent-4-yn-1-ol (VIII) to a double esterification and to a radicalary cyclization, yielding a compound of formula (V), where either a compound of formula (VIII) is submitted to a first esterification reaction, then to a catalytic radicalary cyclization using titanocene dichloride as catalyst in the presence of Mn/2,4,6-collidine HCl or Zn/2,4,6-collidine/trimethylsilyl chloride, and finally to a second esterification reaction or, alternatively, the compound of formula (VIII) is submitted first to a catalytic radicalary cyclization, and then to an esterification reaction. Entecavir can be obtained by submitting compound (V) to a desilylation reaction to remove the TBS group and then to a Mitsunobu coupling with 2-amino-6-chloroguanine, followed by hydrolysis. It also relates to some new intermediates of the process. | 11-07-2013 |
Ramón Castey Dominguez, Girona ES
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20110209307 | HEAT-PROTECTED HANDLE SUITABLE FOR A COOKING VESSEL - The invention relates to a heat-protected handle suitable for a cooking vessel, including a rigid structural part fixed or attached to the cooking vessel and one or more heat protection elements which partially cover the structural part, including a cover made from an elastic material configured to be adapted to and tightly coupled on the structural part such as to cover same at least partially and in a lower region of the cover the configuration provides a portion adjacent to the structural element or vessel which acts as a barrier between the user's fingers and the vessel. | 09-01-2011 |
Ramón Cisterna Cáncer, Jaen ES
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20120308586 | COMPOSITION BASED ON EXTRA VIRGIN OLIVE OILS - This invention relates to a composition based on a mixture of different olive oils, preferably virgin and extra virgin olive oils, from ecological farms, and to the use thereof in the treatment or prevention of different disorders in humans and animals. Moreover, this invention also relates to a dermatological/dermocosmetic preparation that comprises the composition of this invention and to the use of this dermatological/dermocosmetic preparation in the treatment of skin disorders in humans and animals. Underlying these systemic and/or skin disorders, there are metabolic and immunoinflammatory-oxidative alterations, which may be positively modified by the systemic (oral) or topical (cutaneous) use of the composition of this invention. The special physical-chemical structure of the composition allows for a better digestive and cutaneous arrangement. | 12-06-2012 |
Ramón Colomer Bosch, Girona ES
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20100190856 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors - The present invention relates to new polyhydroxylated compounds and, in particular, to its activity as fatty acid synthase (FASN) inhibitors and to their use for the treatment of pathological states for which an inhibitor of this enzyme is indicated. The invention further relate to pharmaceutical compositions containing them and to a process for the preparation of such compounds. | 07-29-2010 |
Ramón Colomer Bosch, Girona ES
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20100190856 | Novel Polyhydroxylated Compounds as Fatty Acid Synthase (FASN) Inhibitors - The present invention relates to new polyhydroxylated compounds and, in particular, to its activity as fatty acid synthase (FASN) inhibitors and to their use for the treatment of pathological states for which an inhibitor of this enzyme is indicated. The invention further relate to pharmaceutical compositions containing them and to a process for the preparation of such compounds. | 07-29-2010 |
Ramón Eritja Casadellá, Barcelona ES
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20130274317 | DERIVATIVES OF SMALL INTERFERING RNAS AND USE THEREOF - The present invention relates to a small interfering RNA (siRNA) being 2′-O-methyl modified and there being attached thereto by a phosphodiester bond a position 3′, wherein group R in position 3′, wherein R is selected from among: a C | 10-17-2013 |
Ramón Farré Berga, Lleida ES
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20110217675 | SCREW TO FIX A PROSTHESIS ON A DENTAL IMPLANT, SURGICAL DRIVER, KIT AND TORQUE KEY (AS AMENDED) | 09-08-2011 |
20120103147 | COUPLING STRUCTURE BETWEEN SCREW HEAD AND TIGHTENING TOOL - A coupling structure between a screw head and a tightening tool includes a recess ( | 05-03-2012 |
20120246916 | ABUTMENT FOR THE MANUFACTURING OF THE INTERNAL STRUCTURE OF DENTAL PROSTHESIS - An Abutment ( | 10-04-2012 |
Ramón Mangues, Barcelona ES
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20100041594 | Use of Aplidine for the Treatment of Pancreatic Cancer - Aplidine is active against cancer of the pancreas, including metastatic pancreatic cancer. | 02-18-2010 |
Ramón Mangues, Barcelona ES
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20100041594 | Use of Aplidine for the Treatment of Pancreatic Cancer - Aplidine is active against cancer of the pancreas, including metastatic pancreatic cancer. | 02-18-2010 |
Ramón Múgica Garay, Madrid ES
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20130095249 | ANTI-GRAFFITI EMULSIONS WITH ANTI-HUMIDITY BARRIER CHARACTERISTIC - The present invention relates to anti-graffiti emulsions comprising at least one type of wax, oil, additives and at least one medium or carrier. Additionally, the present invention relates to a process for preparing an anti-graffiti emulsion, a method for application thereof and a method for cleaning and recovering the protective effect of graffiti-painted surfaces. Finally, the invention relates to the use of the anti-graffiti emulsion for any type of surface against graffiti and sticking of posters. | 04-18-2013 |
Ramón Naranjo-Tackman, Mexico City MX
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20110160710 | LASER SYSTEM AND METHOD FOR PERFORMING AND SEALING CORNEAL INCISIONS IN THE EYE - There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined self-sealing incisions in the cornea. The systems, apparatus and methods further provide laser systems that can provide these incisions in conjunction with the removal and replacement of the natural human crystalline lens. | 06-30-2011 |
20110160711 | LASER SYSTEM AND METHOD FOR CORRECTION OF INDUCED ASTIGMATISM - There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined clear corneal incisions that are capable of reducing induced astigmatism. The systems, apparatus and methods further provide laser systems that can provide these incisions at or below Bowman's membrane. | 06-30-2011 |
20110166557 | LASER SYSTEM AND METHOD FOR ASTIGMATIC CORRECTIONS IN ASSSOCIATION WITH CATARACT TREATMENT - There is provided a system, apparatus and methods for developing laser systems that can create precise predetermined clear corneal incisions that are capable of reducing astigmatism. The systems, apparatus and methods further provide laser systems that can provide these incisions at or below Bowman's membrane and in conjunction a precise predetermined capsulotomy shot pattern. | 07-07-2011 |
Ramón Riera Garriga, Girona ES
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20100295892 | METHOD OF CLEANING A SCRAPER DEVICE - The invention relates to a method of cleaning doctor devices ( | 11-25-2010 |
Ramón Riera Garriga, Girona ES
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20100295892 | METHOD OF CLEANING A SCRAPER DEVICE - The invention relates to a method of cleaning doctor devices ( | 11-25-2010 |
Ramón Sans Rovira, Vic Barcelona ES
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20120096733 | TUNNEL-TYPE ROTARY-DRUM TUMBLE DRYER - A tunnel-type rotary drum tumble dryer includes a cabinet ( | 04-26-2012 |
Ramón Segarra Guerrero, Valencia ES
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20110224290 | COMBINE USE OF PTEROSTILBENE AND QUERCETIN FOR THE PRODUCTION OF CANCER TREATMENT MEDICAMENTS - The invention relates to the combined use of pterostilbene and quercetin for the production of cancer treatment medicaments. The in vitro growth of melanoma cells B16-F10 (B16M-F10) is inhibited (56%) by combined exposures of short duration (60 min/day) to PTER (40 μM)+QUER (20 μM) (˜average values of plasma concentrations measured within the first hour following the IV administration of 20 mg of each polyphenol/kg ˜). The combined intravenous administration of PTER+QUER (20 mg/kg×day) to mice inhibits (73%) the metastatic growth of melanoma B16M-F10 in the liver, a common site for metastasis development. The invention demonstrates that the combination of PTER+QUER inhibits the growth of malignant melanoma metastasis and prolongs the survival of the carrier host. | 09-15-2011 |
Ramón Tamarit Rios, Puzol ES
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20110108552 | DOUBLE OPENING SYSTEM FOR BEVERAGE CANS - The lid of a beverage can has two punched segments, breaking of which forms the respective openings for allowing the liquid to flow out and the air to enter. Breaking of these punched parts is performed by pivoting upwards a main ring mounted on a rivet of the lid and, after breaking open the punched part, pushing downwards a secondary lever with cutting pressure pieces which cut into the punched parts so as to cause breakage thereof. The said secondary lever is mounted on the same rivet, having an end segment which rests against a stop of the ring in order to prevent in the rest condition the pressure pieces cutting into the punched parts. In another simpler embodiment, the secondary lever is dispensed with, so that the pressure piece is incorporated along the contour of the associated main ring. | 05-12-2011 |
Ramón Tamarit Rios, Puzol ES
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20110108552 | DOUBLE OPENING SYSTEM FOR BEVERAGE CANS - The lid of a beverage can has two punched segments, breaking of which forms the respective openings for allowing the liquid to flow out and the air to enter. Breaking of these punched parts is performed by pivoting upwards a main ring mounted on a rivet of the lid and, after breaking open the punched part, pushing downwards a secondary lever with cutting pressure pieces which cut into the punched parts so as to cause breakage thereof. The said secondary lever is mounted on the same rivet, having an end segment which rests against a stop of the ring in order to prevent in the rest condition the pressure pieces cutting into the punched parts. In another simpler embodiment, the secondary lever is dispensed with, so that the pressure piece is incorporated along the contour of the associated main ring. | 05-12-2011 |
Ramón Torrecillas San Millán, Oviedo ES
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20110301016 | MATERIALES BASADOS EN ALUMINOSILICATOS DE LITIO CON COEFICIENTE DE EXPANSION TERMICA NEGATIVOS EN UN AMPLIO INTERVALO DE TEMPERATURA, PROCEDIMIENTO DE PREPARACION Y USO - New process for obtaining lithium aluminosilicate-based (LAS) ceramic materials having a near-zero and negative thermal expansion coefficient within a temperature range of (−150° C. to 450° C.). These materials are applicable to the manufacture of components that require a high level of dimensional stability. | 12-08-2011 |
Ramón Torrecillas San Millán, Bendones ES
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20120040005 | NANOSTRUCTURED CALCIUM-SILVER PHOSPHATE COMPOSITE POWDERS, PROCESS FOR OBTAINING THE POWDERS, AND BACTERICIDAL AND FUNGICIDAL APPLICATIONS THEREOF - Described in example embodiments are nanocomposite powders including calcium phosphate and silver nanoparticles on the surface of the calcium phosphate. Other example embodiments, describe methods of forming nanocomposite powders comprising a) preparing a nanometric calcium phosphate by a sol-gel processing route; and b) depositing silver nanoparticles on the calcium phosphate surface. Compositions including nanocomposite powders and uses of those compositions are also described. | 02-16-2012 |
Ramón Trullas Oliva, Barcelona ES
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20110070234 | NP1 ACTIVITY REGULATING ELEMENTS USEFUL FOR THE PRODUCTION OF DRUGS FOR THE TREATMENT OR PREVENTION OF HUMAN NEURODEGENERATIVE DISEASES, RESULTING DRUGS AND USE THEREOF - The invention relates to a series of compounds useful for the production of drugs or pharmaceutical compositions for the treatment or prevention of human neurological diseases, preferably neurodegenerative diseases, which inhibit the activity of the human NP1 protein which acts as an inducer of neurodegeneration and neural apoptosis. Said compounds include iRNA inhibitors of the gene expression of the NP1 gene and specific antibodies of the human NP1 protein, as well as peptides derived from same, which can be used in passive and active immunisation methods respectively against said diseases. | 03-24-2011 |
Ramón Trullas Oliva, Barcelona ES
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20110070234 | NP1 ACTIVITY REGULATING ELEMENTS USEFUL FOR THE PRODUCTION OF DRUGS FOR THE TREATMENT OR PREVENTION OF HUMAN NEURODEGENERATIVE DISEASES, RESULTING DRUGS AND USE THEREOF - The invention relates to a series of compounds useful for the production of drugs or pharmaceutical compositions for the treatment or prevention of human neurological diseases, preferably neurodegenerative diseases, which inhibit the activity of the human NP1 protein which acts as an inducer of neurodegeneration and neural apoptosis. Said compounds include iRNA inhibitors of the gene expression of the NP1 gene and specific antibodies of the human NP1 protein, as well as peptides derived from same, which can be used in passive and active immunisation methods respectively against said diseases. | 03-24-2011 |