Patent application number | Description | Published |
20080291391 | HYBRID CONTACT LENSES PREPARED WITH EXPANSION CONTROLLED POLYMERIC MATERIALS - A hybrid contact lens includes a substantially rigid center portion and a substantially flexible skirt portion connected to the center portion. The skirt portion is formed using xerogels compatible with diluents comprising at least one selected from polylactic acid, polyglycolic acid, lactide, glycolide, a polyacetal, a cyclic acetal, a polyketal, a cyclic ketal, a polyorthoester, a cyclic orthoester, di-t-butyl-dicarbonate, tris(trimethylsilyl)amine, and 2,2,2-trifluoroacetamide. These diluents are formulated to function as a stand-in for water in the xerogel polymer, allowing the xerogel to form and bond to the rigid center portion in its fully expanded state. Upon hydration of the hybrid lens, substantially little dimensional change, and thus substantially little distortion, is obtained in the skirt portion. The diluents of the present invention further preserve the mechanical integrity of the xerogel, allowing the xerogel to be machined to final shape, improving the dimensional tolerances which can be achieved in the hybrid lens. | 11-27-2008 |
20100208196 | Surface Modification of Contact Lenses - Contact lenses which exhibit improved wetability are provided. In one aspect, the surface of the contact lenses may be modified using a hydrophilic layer which imparts improved wetability to the contact lens. The contact lens may be exposed to a first plasma so as to generate free radicals on the contact lens surface. An organic compound may be further reacted with the free radicals on the surface to form an organic coating. The contact lens may be exposed to a under conditions selected to oxidize the organic coating and form the hydrophilic layer. Surface modified contact lenses may exhibit contact angles with respect to water less than about 50° using a broad range of organic compounds, including alcohols, ethers, aldehydes, ketones, esters, organosilicon, organophosphorous, organotitanium, organotin, organogermanium, and organoboron compounds. The improved wetability is also substantially maintained when the lens is subject to wear. | 08-19-2010 |
Patent application number | Description | Published |
20080212894 | METHOD AND APPARATUS FOR SIMULATION OF FACIAL SKIN AGING AND DE-AGING - A novel method and system is disclosed to realistically simulate the progress or worsening of facial skin features that contribute to the overall look and condition of the skin. The method utilizes two close-up photographs of the face, one is captured with a digital camera in standard white light, and the other is captured with the same camera in UV light. Then, the method processes these images to simulate the progress or worsening of the major skin features: hyperpigmented spots, wrinkles and small texture features. The worsening of these features simulates facial skin aging due to prolonged exposures to sunlight, biological aging or degradation of the skin health. The progress of these features simulates the improvement of facial skin in terms of overall look and healthiness as though the patient has gone through a treatment. Therefore, the present invention discloses a series of methods that are useful in dermatology, cosmetics and computer animations. | 09-04-2008 |
20090028380 | METHOD AND APPARATUS FOR REALISTIC SIMULATION OF WRINKLE AGING AND DE-AGING - Methods and systems are disclosed to realistically simulate facial wrinkle aging of a person using a neutral state (natural look) image and one or more expression images (e.g., smile, frown, pout, wink) that induce wrinkles. The neutral and expression images are processed to simulate wrinkle aging by registering the wrinkles that are visible in the expression image onto the neutral image, thereby generating a wrinkle-aged simulated image. Advantageously, a person's own wrinkle histological data is utilized, hence providing an accurate and realistic wrinkle aging simulation. Similarly, the neutral image is processed to eliminate all visible wrinkles thereby generating a wrinkle de-aged simulation image. Additionally, blending of a neutral image with an aged or de-aged simulation image is disclosed, where the degree of blending is based on statistical modeling of skin condition with age and/or expected outcome of a particular type of treatment. The methods and systems disclosed have wide applicability, including, for example, areas such as dermatology, cosmetics and computer animation, among others. | 01-29-2009 |
20090196475 | AUTOMATIC MASK DESIGN AND REGISTRATION AND FEATURE DETECTION FOR COMPUTER-AIDED SKIN ANALYSIS - Methods and systems for automatically generating a mask delineating a region of interest (ROI) within an image containing skin are disclosed. The image may be of an anatomical area containing skin, such as the face, neck, chest, shoulders, arms or hands, among others, or may be of portions of such areas, such as the cheek, forehead, or nose, among others. The mask that is generated is based on the locations of anatomical features or landmarks in the image, such as the eyes, nose, eyebrows and lips, which can vary from subject to subject and image to image. As such, masks can be adapted to individual subjects and to different images of the same subjects, while delineating anatomically standardized ROIs, thereby facilitating standardized, reproducible skin analysis over multiple subjects and/or over multiple images of each subject. Moreover, the masks can be limited to skin regions that include uniformly illuminated portions of skin while excluding skin regions in shadow or hot-spot areas that would otherwise provide erroneous feature analysis results. Methods and systems are also disclosed for automatically registering a skin mask delineating a skin ROI in a first image captured in one imaging modality (e.g., standard white light, UV light, polarized light, multi-spectral absorption or fluorescence imaging, etc.) onto a second image of the ROI captured in the same or another imaging modality. Such registration can be done using linear as well as non-linear spatial transformation techniques. | 08-06-2009 |