Patent application number | Description | Published |
20110097305 | Gem-Disubstituted and Spirocyclic Amino Pyridines/Pyrimidines as Cell Cycle Inhibitors - Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-me-dialed disorders, such as cancer. The subject compounds arc gem-disubstituted or spimcyclic pyridine, pyrimidine and triazine derivatives. | 04-28-2011 |
20110142796 | Fused Pyridine, Pyrimidine and Triazine Compounds as Cell Cycle Inhibitors - Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-mediated disorders, such as cancer. The subject compounds are fused pyridine, pyrimide and triazine derivatives. | 06-16-2011 |
20120214854 | CARBOXY OXAZOLE OR THIAZOLE COMPOUNDS AS DGAT- 1 INHIBITORS USEFUL FOR THE TREATMENT OF OBESITY - Heteroaryl compounds, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or disorders mediated by Diacylglycerol acyltransferase (DGAT) enzyme, particularly DGAT-1 is described. | 08-23-2012 |
20120232072 | IMIDAZOPYRIDINE DERIVATIVES - The present invention relates to compounds of formula (I), | 09-13-2012 |
20120289505 | INHIBITORS OF DIACYLGLYCEROL ACYL TRANSFERASE - The present invention relates to heterocyclic compounds in all their stereoisomeric and tautomeric forms; and their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutically acceptable polymorphs. The invention also relates to processes for the manufacture of the heterocyclic compounds and to pharmaceutical compositions containing them. The said compounds and their pharmaceutical compositions are useful in the prevention and treatment of diseases or disorders mediated by diacylglycerol acyltransferase (DGAT), particularly DGAT1. The present invention further provides a method of treatment of such diseases or disorders by administering a therapeutically effective amount of said compounds or their pharmaceutical compositions, to a mammal in need thereof. | 11-15-2012 |
20130116248 | SUBSTITUTED IMIDAZOQUINOLINE DERIVATIVES AS KINASE INHIBITORS - The present invention relates to substituted imidazo[4,5-c]quinoline derivatives, the compounds of formula (I), wherein R | 05-09-2013 |
20130158075 | HETEROCYCLIC COMPOUNDS AS DGAT1 INHIBITORS - The present invention relates to heterocyclic compounds of formula 1, in all their stereoisomeric and tautomeric forms; and their pharmaceutically acceptable salts, solvates, polymorphs, prodrugs, carboxylic acid isosteres and N-oxides. The invention also relates to processes for the manufacture of the heterocyclic compounds and to pharmaceutical compositions containing them. The said compounds and their pharmaceutical compositions are useful in the prevention and treatment of diseases or disorders mediated by diacylglycerol acyltransferase (DGAT), particularly DGAT1. The present invention further provides a method of treatment of such diseases or disorders by administering a therapeutically effective amount of said compounds or their pharmaceutical compositions, to a mammal in need thereof. | 06-20-2013 |
20130310374 | Substituted Imidazoquinoline Derivatives - The present invention relates to substituted imidazo[4,5-c]quinoline derivatives of formula (I), wherein R | 11-21-2013 |
20140045832 | Insulin-Like Growth Factor-1 Receptor Inhibitors - The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating Insulin-Like-Growth Factor I Receptor and Insulin Receptor. The compounds of the instant invention possess a core structure that comprises a sulfonyl indole moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds. | 02-13-2014 |
20150072969 | PHENYL ALKANOIC ACID DERIVATIVES AS GPR AGONISTS - The present invention relates to phenyl alkanoic acid derivatives (the compounds of Formula (I)); and their isotopic forms, stereoisomeric and tautomeric forms and mixtures thereof in all ratios, or pharmaceutically acceptable salts, pharmaceutically acceptable solvates, prodrugs, polymorphs, N-oxides, S-oxides or carboxylic acid isosteres thereof. The invention also relates to processes for the preparation of compounds of Formula (I) | 03-12-2015 |
20150080312 | HEXADEPSIPEPTIDE ANALOGUES AS ANTICANCER COMPOUNDS - This invention relates to an isolated, compound of Formula (1) | 03-19-2015 |