Rajasekaran, US
Ayyappan K. Rajasekaran, Glen Mills, PA US
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20150140071 | KINASE INHIBITORS - The disclosed molecules are inhibitors of Bcr-Abl and Src kinases. The molecules are cytotoxic to Gleevec resistant cells. Inhibitors of Bcr-Abl and Src kinases are used in the treatment of Chronic Myelogenous Leukemia among other diseases. | 05-21-2015 |
John J. Rajasekaran, Los Altos, CA US
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20080242561 | MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS - Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of branched peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner. | 10-02-2008 |
20080318808 | MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS - Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of branched peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner. | 12-25-2008 |
20090258796 | MASSIVELY PARALLEL SYNTHESIS OF BIOPOLYMERIC ARRAYS - Methods for fabricating dense arrays of polymeric molecules in a highly multiplexed manner are provided using semiconductor-processing-derived lithographic methods. Advantageously, the methods are adaptable to the synthesis of a variety of polymeric compounds. For example, arrays of branched peptides and polymers joined by peptide bonds may be fabricated in a highly multiplexed manner. | 10-15-2009 |
20100240555 | Method for high throughput, high volume manufacturing of biomolecule micro arrays - The embodiments of the invention relate to a system and method for making a biomolecule microarray comprising a spacer attachment module adapted to attach a linker to a substrate surface of the biomolecule microarray, a coupling module adapted to couple a molecule to the linker, the molecule being capable of forming a peptide bond and containing a protecting group that prevents the formation of the peptide bond, and a deprotection module adapted to create deprotection of the protecting group with a radiation exposure of about 1-50 mJ/cm | 09-23-2010 |
John J. Rajasekaran, Hillsborough, CA US
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20140349888 | Substrates, Peptide Arrays, and Methods - Disclosed herein are formulations, substrates, and arrays. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays. Also disclosed are methods for identifying peptide sequences useful for diagnosis and treatment of disorders, and methods for using the peptide sequences for diagnosis and treatment of disorders, e.g., celiac disorder. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. | 11-27-2014 |
Kulothungan Rajasekaran, Sammamish, WA US
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20090125623 | DATA VALIDATION USING SIGNATURES AND SAMPLING - Architecture that facilitates validation of a data mapping of data from a data source to a data target. There is included a signature generation component that generates a source signature of all or a portion of the data source and a target signature of all or a corresponding portion of the data target, and a sampling component that obtains a sample of the source data a corresponding sample of the target data. The data signatures and data samples are compared respectively and processed with a processing component to determine the status of the validation process. | 05-14-2009 |
20090132461 | DATA VALIDATION USING SIGNATURES AND SAMPLING - Architecture that facilitates validation of a data mapping of data from a data source to a data target. There is included a signature generation component that generates a source signature of all or a portion of the data source and a target signature of all or a corresponding portion of the data target, and a sampling component that obtains a sample of the source data a corresponding sample of the target data. The data signatures and data samples are compared respectively and processed with a processing component to determine the status of the validation process. | 05-21-2009 |
20090132955 | DATA VALIDATION USING SIGNATURES AND SAMPLING - Architecture that facilitates validation of a data mapping of data from a data source to a data target. There is included a signature generation component that generates a source signature of all or a portion of the data source and a target signature of all or a corresponding portion of the data target, and a sampling component that obtains a sample of the source data a corresponding sample of the target data. The data signatures and data samples are compared respectively and processed with a processing component to determine the status of the validation process. | 05-21-2009 |
Manodev J. Rajasekaran, Pullman, WA US
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20140211624 | Network Device - Disclosed is a network communication switch that facilitates reliable communication of high priority traffic over lower priority traffic across all ingress and egress ports. The network communication switch may monitor the frame storage buffer regardless of egress port, and when the frame storage buffer reaches a predetermined level, the switch may discard lower priority frames from the most congested port. When the frame storage buffer reaches a second predetermined level, the switch may discard lower priority frames before they are stored according to egress port. The network communication switch may further monitor ingress frames for priority, and assign priority to frames according to pre-assigned priority, ingress port, and/or frame contents. | 07-31-2014 |
Mohan Rajasekaran, Bristol, CT US
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20110092996 | Surgical knife safety handle - A surgical knife safety device having a handle, a blade connected to the handle, and a guard carried by the handle for sliding movement between a retracted position in which the blade is exposed for use, and an extended position for covering the sharp cutting edge of the blade. In the retracted position, an enlarged guard radius is provided at the distal end of the handle to allow improved handle control and blade orientation. The enlarged guard radius is positioned to allow the user to firmly grip a large distal handle portion which is preferably molded as a single piece with the blade holder, preventing unwanted blade or handle movement due to guard mechanism tolerances. | 04-21-2011 |
20130204284 | Surgical Knife Safety Handle - A surgical knife safety device having a handle, a blade connected to the handle, and a guard carried by the handle for sliding movement between a retracted position in which the blade is exposed for use, and an extended position for covering the sharp cutting edge of the blade. In the retracted position, an enlarged guard radius is provided at the distal end of the handle to allow improved handle control and blade orientation. The enlarged guard radius is positioned to allow the user to firmly grip a large distal handle portion which is preferably molded as a single piece with the blade holder, preventing unwanted blade or handle movement due to guard mechanism tolerances. | 08-08-2013 |
Namakal S. Rajasekaran, Salt Lake City, UT US
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20140220152 | Compositions and Methods for Detecting, Treating, or Preventing Reductive Stress - Disclosed herein is a non-human animal model of protein aggregation cardiomyopathy. Also disclosed are compositions and methods of treating or preventing a condition in a subject caused or exacerbated by reductive stress. Also disclosed are compositions and methods of predicting, detecting, or monitoring reductive stress in a subject. | 08-07-2014 |
Namakkal S. Rajasekaran, Salt Lake City, UT US
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20120030779 | COMPOSITIONS AND METHODS FOR DETECTING, TREATING, OR PREVENTING REDUCTIVE STRESS - Disclosed herein is a non-human animal model of protein aggregation cardiomyopathy. Also disclosed are compo-sitions and methods of treating or preventing a condition in a subject caused or exacerbated by reductive stress. Also disclosed are compositions and methods of predicting, detecting, or monitoring reductive stress in a subject. | 02-02-2012 |
Sanguthevar Rajasekaran, Ellington, CT US
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20090138944 | METHOD AND APPARATUS FOR CAMOUFLAGING OF DATA, INFORMATION AND FUNCTIONAL TRANSFORMATIONS - A computer-representable object (including, without limitation, a cryptographic key, or a graph or a Boolean description of a system) is secured using a generalized camouflaging technique. The secured object need not be stored in the system, not even in encrypted form. Instead, the technique employs a composition function that regenerates the secured object when one inputs a valid password (which may be any computer-representable information held by a user). By regenerating the secured object each time a valid password is entered, there is no need to store the secured object. If one inputs an invalid password, the technique may generate an incorrect object, such that the user is unable to distinguish this incorrect object from the secured object. If the user tries to use the incorrect object, the user can be exposed as unauthorized, without the user's knowledge that he has been exposed. | 05-28-2009 |
Sanguthevar Rajasekaran, Los Altos, CA US
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20090138706 | TECHNIQUES FOR SEARCHING ENCRYPTED FILES - Techniques for efficiently searching encrypted searchable spaces. For example, embodiments of the present invention provide techniques for searching a plurality of files that are stored in encrypted (or ciphertext) form. According to embodiments of the present invention, the search can usually be performed by decrypting only a portion of the encrypted searchable space. According to an embodiment of the present invention, the search techniques determine a set of files comprising one or more files from the plurality of encrypted files that contain a user-specified query element. The set of files is usually determined by decrypting only a subset of the plurality of encrypted files. | 05-28-2009 |
Varun Prem Sagar Rajasekaran, Parrish, FL US
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20110113795 | MODULAR HEATING, VENTILATING, AIR CONDITIONING, AND REFRIGERATION SYSTEMS AND METHODS - Embodiments of a modular air conditioning (AC) unit include a base unit and a blower selected from a group of blowers configured for different cooling capacities. The module AC unit also includes at least one heat exchanger unit selected from a group of substantially identical modular heat exchanger units, the number of heat exchanger units being selected based upon the desired cooling capacity. The at least one heat exchanger unit and the blower are assembled to the base unit to form a modular air conditioning circuit. | 05-19-2011 |
20110113801 | CONDENSER ASSEMBLIES FOR HEATING, VENTILATING, AIR CONDITIONING, AND REFRIGERATION SYSTEMS - Embodiments of a modular condenser unit are provided. The modular condenser unit may include a housing and a first condenser coil and a second condenser coil disposed within a volume of the housing. A fan may also be disposed in an end of the housing and adapted to draw air through at least one of the first condenser coil and the second condenser coil. In some embodiments, the first condenser coil and/or the second condenser coil may be micro-channel condenser coils. | 05-19-2011 |
20120067965 | CONTROL SYSTEMS AND METHODS FOR MODULAR HEATING, VENTILATING, AIR CONDITIONING, AND REFRIGERATION SYSTEMS - Embodiments of a modular air conditioning (AC) unit include a base unit, a blower mounted to the base unit, and at least one heat exchanger module assembled to the base unit and communicatively coupled to the blower to form a modular AC circuit. The modular AC unit also includes a controller communicatively coupled to at least one component of the modular AC circuit and adapted to independently control operation of each of the components of the modular AC circuit. | 03-22-2012 |
Varun Prem Sagar Rajasekaran, Schaumburg, IL US
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20150028026 | SLIDABLE BIN WITHIN A REFRIGERATOR DRAWER - A bin positioned within a refrigerator drawer and slidable across the refrigerator drawer at one or more edges of the refrigerator drawer and/or at one or more sliding mechanisms attached to at least one side of the refrigerator drawer. | 01-29-2015 |
Vijay Rajasekaran, San Jose, CA US
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20090272881 | Apparatus, method, and system providing pixel having increased fill factor - A method, apparatus, and system providing a pixel having increased fill factor by removing the row select transistor. A reset transistor in the pixel is connected to a column line, and the column line is used alternatively as a pixel readout line and as a voltage supply line for resetting a storage region in the pixel through the resent transistor. | 11-05-2009 |
Vijay Rajasekaran, Santa Clara, CA US
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20120218451 | IMAGING PIXELS WITH DUMMY TRANSISTORS THAT REDUCE RESET CHARGE INJECTION - An imaging system may include imaging pixels. Each imaging pixel may include a reset transistor and a dummy transistor coupled to a floating diffusion storage node. When reset signals control are deasserted, capacitive coupling between the gate terminal of the reset transistor and the source-drain terminals of the reset transistor may lead to reset charge injection. The dummy transistor may have both of its source-drain terminals shorted together and shorted to the floating diffusion region. Dummy control signals, which may be provided by separate dummy control lines or may be provided using row-select signals, may be asserted on the dummy transistors at approximately the same time that the reset signals are deasserted. With arrangements of this type, the dummy control signals may inject an approximately equal and opposite charge onto the floating diffusion region, thereby reducing the reset charge injection caused by deasserting the reset control signals. | 08-30-2012 |
Vinod Rajasekaran, Houston, TX US
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20080265898 | DETERMINING ELECTRICAL CHARACTERISTICS OF AN ELECTRICAL CABLE - To characterize an electrical cable that is deployed in a well, a voltage input is applied to the electrical cable at an earth surface location, where the well extends from the earth surface location. A current response resulting from the voltage input is measured at the earth surface location. At least one parameter of the electrical cable is computed according to the measured current response. | 10-30-2008 |
20090322554 | Determining Electrical Characteristics of an Electrical Cable - To characterize an electrical cable that is deployed in a well, a voltage input is applied to the electrical cable at an earth surface location, where the well extends from the earth surface location. A current response resulting from the voltage input is measured at the earth surface location. At least one parameter of the electrical cable is computed according to the measured current response. | 12-31-2009 |