Raftery
Daniel Raftery, West Lafayette, IN US
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20110202285 | NMR METHOD FOR DIFFERENTIATING COMPLEX MIXTURES - A method for differentiating complex mixtures each having one or more chemical species is provided. The method comprises producing a sample NMR spectrum by subjecting a mixture to a selective spectroscopy process, wherein the NMR spectrum has individual spectral peaks representative of the one or more chemical species within the mixture. The one or more chemical species within the mixture are identified by analyzing the individual spectral peaks, and the individual spectral peaks are then subjected to a multivariate statistical analysis. | 08-18-2011 |
Daniel M. Raftery, Lafayette, IN US
Emmet Raftery, Ontario CA
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20110129096 | METHOD AND SYSTEM FOR REDUCING ACOUSTICAL REVERBERATIONS IN AN AT LEAST PARTIALLY ENCLOSED SPACE - A method of increasing the intelligibility of an audio broadcast in an at least partially enclosed space from at least one amplified audio source. An input microphone receives an incident audio wavefront at a first position in the at least partially enclosed space. An active noise control system is employed to generate a cancelling audio wavefront having a magnitude substantially equal to the magnitude of incident audio wavefront and a phase substantially opposite to the phase of the incident audio wavefront. The cancelling audio wavefront is broadcast at a second position in the at least partially enclosed space adjacent to a reflective surface of the at least partially enclosed space so as to attenuate the incident audio wavefront substantially at or near the reflective surface in order to reduce reverberations of the incident audio wavefront. In this manner, reverberations which could reduce the intelligibility of the audio broadcast to an audience is reduced. | 06-02-2011 |
M. Daniel Raftery, Seattle, WA US
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20130023056 | EARLY DETECTION OF RECURRENT BREAST CANCER USING METABOLITE PROFILING - A monitoring test for recurrent breast cancer with a high degree of sensitivity and specificity is provided that detects the presence of a panel of multiplicity of biomarkers that were identified using metabolite profiling methods. The test is capable of detecting breast cancer recurrence about a years earlier than current available monitoring diagnostic tests. The panel of biomarkers is identified using a combination of nuclear magnetic resonance (NMR) and two dimensional gas chromatography-mass spectrometry (GC×GC-MS) to produce the metabolite profiles of serum samples. The NMR and GC×GC-MS data are analyzed by multivariate statistical methods to compare identified metabolite signals between samples from patients with recurrence of breast cancer and those from patients having no evidence of disease. | 01-24-2013 |
20130282300 | Combined Spectroscopic Method for Rapid Differentiation of Biological Samples - A method for differentiating complex biological samples, each sample having one or more metabolite species. The method comprises producing a mass spectrum by subjecting the sample to a mass spectrometry analysis, the mass spectrum containing individual spectral peaks representative of the one or more metabolite species contained within the sample; subjecting the individual spectral peaks of the mass spectrum to a statistical pattern recognition analysis; identifying the one or more metabolite species contained within the sample by analyzing the individual spectral peaks of the mass spectrum; and assigning the sample into a defined sample class. | 10-24-2013 |
20140148349 | Metabolite Biomarkers for the Detection of Esophageal Cancer Using NMR - Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. In other aspects, methods for detection and screening for the progression of high-risk conditions (BE and HGD) to EAC and to monitoring treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. The biomarkers are sensitive and specific for the detection of EAC, and can also be used to classify Barrett's esophagus (BE) and high-grade dysplasia (HGD), which are widely regarded as precursors of EAC. | 05-29-2014 |
20140162903 | Metabolite Biomarkers For Forecasting The Outcome of Preoperative Chemotherapy For Breast Cancer Treatment - The present disclosure relates to a panel of metabolite species that is useful for forecasting the outcome of preoperative chemotherapy for the treatment of breast cancer, including methods for identifying and using such metabolite species that can be measured in biological samples taken before treatment. In preferred embodiments, a method of forecasting a treatment outcome before subjecting a breast cancer patient to preoperative chemotherapy is disclosed that includes measuring the concentration of at least one metabolite species in a sample of a biofluid taken from the breast cancer patient before preoperative chemotherapy treatment. | 06-12-2014 |
20150056605 | IDENTIFICATION OF BLOOD BASED METABOLITE BIOMARKERS OF PANCREATIC CANCER - The present disclosure relates to a panel of a plurality of metabolite species that is useful for the identification or detection of subjects having pancreatic cancer, including methods for identifying such metabolic biomarkers within biological samples. The disclosure also includes a statistical model for predicting the presence of pancreatic cancer in a subject's biofluid by quantifying and comparing positive and negative fold changes in metabolite species' concentration; comparing the subject's metabolite species' concentrations to a predetermined value. | 02-26-2015 |
M. Daniel Raftery, West Lafayette, IN US
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20110123976 | Biomarkers and identification methods for the early detection and recurrence prediction of breast cancer using NMR - A method is provided for the parallel identification of one or more metabolite species within a biological sample. The method comprises analyzing the sample to produce a spectrum containing individual spectral peaks representative of the one or more metabolite species contained within the sample; subjecting each of the individual spectral peaks to a statistical pattern recognition analysis to identify the one or more metabolite species contained within the sample; and identifying the one or more metabolite species contained within the sample by analyzing the individual spectral peaks of the spectra. | 05-26-2011 |
20120107955 | METABOLITE BIOMARKERS FOR THE DETECTION OF ESOPHAGEAL CANCER USING MS - Results of studies of nucleosides in biofluid specimens from patients with esophageal adenocarcinoma and related disorders have identified five biomarkers of the conditions: 1-methyladenosine, N | 05-03-2012 |
20120142542 | Metabolite Biomarkers for the Detection of Esophageal Cancer Using NMR - Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. In other aspects, methods for detection and screening for the progression of high-risk conditions (BE and HOD) to EAC and to monitoring treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. The biomarkers are sensitive and specific for the detection of EAC, and can also be used to classify Barrett's esophagus (BE) and high-grade dysplasia (HOD), which are widely regarded as precursors of EAC. | 06-07-2012 |
Michael Daniel Raftery, Seattle, WA US
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20150133331 | METABOLITE BIOMARKERS FOR THE DETECTION OF LIVER CANCER - Methods for the detection and screening of hepatocellular carcinoma (HCC) patients and for the monitoring of HCC treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. In other aspects, methods for detection and screening for the progression of high-risk conditions, such as HCV infections, to HCC and to monitoring treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. The biomarkers are sensitive and specific for the detection of HCC, and can also be used to classify HCV infections that are regarded as precursors of HCC. | 05-14-2015 |
Michael William Raftery, Hawley, PA US
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20080217921 | WAVE ENERGY HARNESSING DEVICE - A system for converting fluid surface wave energy into electrical energy. The system includes an electrical generating device, positioned in a waterproof housing, for producing electrical energy. A float, deployed on the fluid surface, is attached to the generating device when the housing is submerged within the fluid. Vertical motion of the surface waves produce vertical motion of the float, which turns and powers the electrical generating device. A plurality of anchors, positioned on the fluid floor, are attached to the housing so that the housing may be positioned proximate the fluid surface for creating a shoaling effect when a plurality of systems are deployed on the fluid surface. | 09-11-2008 |
20100025993 | WAVE ENERGY HARNESSING DEVICE - A hydrokinetic device having a water surface float tethered to a submerged buoyant housing is provided with mechanisms for optimizing the amount of wave energy extracted from the waves by the device. Based on wave conditions, the optimization functionalities include controlling the depth of the housing to produce wave shoaling or storm avoidance, as well as to perform continuous phase control and load control for the purpose of matching the response frequency of the device to the frequency of the incident waves. | 02-04-2010 |
Paul Raftery, Red Hill AU
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20120130875 | ASSET ACQUISITION, MANAGEMENT AND OCCUPATION SYSTEMS AND METHODS - Asset acquisition, management and/or occupation systems and methods are disclosed. One of the methods of acquiring an asset includes a first party approving the asset selected by a second party and the first party purchasing the asset. The method includes the first party and the second party agreeing that the second party has an option or right to purchase, lease, license, or settle or not settle the purchase of the asset from the first party at or before a predetermined time. | 05-24-2012 |
Paul Anthony Raftery, Red Hill AU
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20110145118 | ASSET ACQUISITION, MANAGEMENT AND OCCUPATION SYSTEMS AND METHODS - Asset acquisition, management and/or occupation systems and methods are disclosed. One of the methods of acquiring an asset includes a first party approving the asset selected by a second party and the first party purchasing the asset. The method includes the first party and the second party agreeing that the second party has an option or right to purchase, lease, license, or settle or not settle the purchase of the asset from the first party at or before a predetermined time. | 06-16-2011 |
Stephanie S. Raftery, Kent, CT US
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20080209615 | SELF-CONSTRICTING PONYTAIL LOOP - A self-constricting loop in a hat, headband, or other headwear restrains a ponytail by constricting when the loop is under tension. The loop is created from a gap in the lower edge of an article of headwear. The portion of the gap nearest the lower edge has overlapping tails mutually attached along the lower edge, leaving an opening offset from the lower edge. When the lower edge is not under tension, the opening can be expanded in area by spreading the opening while the lower edge twists. When a ponytail is drawn through the expanded loop and the headwear is placed on a head, the lower edge is straightened, forcing the opening to constrict, thereby restraining the ponytail. | 09-04-2008 |
William Raftery, Canton, OH US
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20100133893 | CHAIR HAVING ELASTIC BANDS FOR SUPPORT SURFACES AND DEVICE FOR SECURING THE BANDS TO THE CHAIR - A chair uses multiple elastic bands to form the seating surfaces. The elastic bands are held in place with a mounting bracket which facilitates easy assembly of the chair and reduces the likelihood of breakage or improper assembly of the elastic bands. The elastic bands are positioned nearly level with the chair side rails and mounting bracket, and the elastic bands cover the mounting screws to provide a chair which is more comfortable and more aesthetically pleasing. | 06-03-2010 |
William Barret Raftery, Canton, OH US
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20110314707 | SKID FOR A SNOW BLOWER AND A SNOW BLOWER INCORPORATING THE SAME - A skid for use on a snow blower, where the snow blower includes an auger housing through which snow removed from an area is channeled. The skid includes a body that is secured to a vertical side wall of the auger housing. The body includes a sliding surface which assists the auger housing in sliding over snow-covered regions of the area being cleared; and a rolling surface which assists the auger housing to travel over snow-free regions of the area. A slot is provided in the sliding surface of the skid and a portion of the rolling surface projects for a distance below the sliding surface. An adapter plate may be positioned between the body and the side wall of the auger housing. The adapter plate enables the body to be secured to different makes of auger housing. | 12-29-2011 |