Patent application number | Description | Published |
20080280374 | METHODS AND SYSTEMS FOR DETECTING BIOLOGICAL AND CHEMICAL MATERIALS ON A SUBMICRON STRUCTURED SUBSTRATE - Methods and systems for detecting biological or biochemical analytes generally comprising, a metal film having one or more surfaces comprising one or more submicron structures; a device for applying one or more analytes to at least a portion of the film surface to interact with said metal film; a light source for illuminating a surface of the metal film so that at least some of the light is adapted to be optically altered by the functionalized metal film; and an optical detection subsystem for collecting the optically altered light, wherein the altered light is indicative of surface plasmon resonance on the film, and detecting one or more properties of the analytes based on the collected light. | 11-13-2008 |
20080302672 | SYSTEMS AND METHODS FOR SENSING - A sensor system for measuring a plurality of chemical species is disclosed. The sensor system includes a plurality of semiconductor device sensor elements, wherein each sensor element includes at least one wide band gap semiconductor layer and at least one catalytic layer configured to have an electrical property modifiable on exposure to an analyte including one or more chemical species; and an acquisition and analysis system configured to receive sensor signals from the plurality of sensor elements and to use multivariate analysis techniques to analyze the sensor signals to provide multivariate analyte measurement data. | 12-11-2008 |
20090044603 | ARTICLE, DEVICE, AND METHOD - An article includes a substrate assembly for use in a detector system. The substrate assembly includes a substrate; a sample reception structure secured to the substrate; a test window extending through the substrate; and a fluid channel defined by a surface of the substrate and extending from the sample reception structure to the test window. | 02-19-2009 |
20090204250 | SYSTEM AND METHOD FOR INTEGRATING RFID SENSORS IN MANUFACTURING SYSTEM COMPRISING SINGLE USE COMPONENTS - The present invention provides a system and method for measuring physical, chemical and biological properties of a manufacturing system comprising embedding a plurality of RFID sensors in a plurality of corresponding single use components wherein each of the plurality of RFID sensors is configured to provide multi-parameter measurements for at least one single use component from the plurality of single use components, and each of the plurality of RFID sensors is further configured to provide simultaneous digital identification for the single use component and for its respective RFID sensor and further comprises reading the multi-parameter measurements and the digital identification for the plurality of single use components using at least one RFID writer/reader, processing the measurements using a processor, and controlling subsequent process steps by comparing the measurements of at least one parameter to a predetermined value. | 08-13-2009 |
20090210169 | HAND-HELD SYSTEMS AND METHODS FOR DETECTION OF CONTAMINANTS IN A LIQUID - A method for detecting contaminants in a liquid is provided. The method can include filling at least a portion of a sample container interior chamber with a liquid sample and submerging a sensor probe of a hand-held portable sensing device in a liquid sample. The method can additionally include sensing an electrical conductivity of the liquid sample utilizing at least one conductivity sensor and automatically selecting a particular one of a plurality of contaminant concentration detection (CCD) algorithms based on the sensed conductivity. The method can further include setting a sensitivity of at least one ionic species sensor to a sensitivity level particular to the selected CCD algorithm and sensing non-desired contaminants in the liquid sample utilizing the at least one ionic species sensor. A concentration of the non-desired contaminant in the liquid sample is then determined in accordance with the selected CCD algorithm. | 08-20-2009 |
20090256679 | RFID BASED METHODS AND SYSTEMS FOR USE IN MANUFACTURING AND MONITORING APPLICATIONS - Methods and systems for optimizing information associated with RFID devices that, include a memory chip written with redundant data and read by an RFID reader and, are adapted for operation of RFID tags and chemical, biological, and physical RFID sensors that are exposed to gamma radiation, such as disposable devices used in bioprocessing. | 10-15-2009 |
20090257055 | HOLLOW-CORE WAVEGUIDE-BASED RAMAN SYSTEMS AND METHODS - Embodiments of the invention include a system for sensing homonuclear diatomic molecules, such as, for example, nitrogen. Other embodiments include a method for sensing homonuclear diatomic molecules. The system may include a light source, a hollow-core wave-guiding device that exhibits a low attenuation at predetermined operating optical frequencies and is in optical communication with the light source, a gas introduction system for introducing a gaseous medium between the light source and the hollow-core wave-guiding device, and a detector in optical communication with the hollow-core wave-guiding device. | 10-15-2009 |
20090278685 | METHODS AND SYSTEMS FOR CALIBRATION OF RFID SENSORS - Methods and systems for calibration of RFID sensors used in manufacturing and monitoring systems are provided. The methods include measuring impedance of an RFID sensor antenna, relating the measurement of impedance to one or more parameters (such as physical, chemical and biological properties), computing one or more analytical fit coefficients, and storing the one or more analytical fit coefficients on a memory chip of the RFID sensor. Measuring impedance of the RFID sensor may comprise measuring complex impedance which involves measuring complex impedance spectrum, phase angle and magnitude of the impedance, at least one of frequency of the maximum of the real part of the complex impedance, magnitude of the real part of the complex impedance, zero-reactance frequency, resonant frequency of the imaginary part of the complex impedance, and antiresonant frequency of the imaginary part of the complex impedance. Also provided are manufacturing or monitoring systems comprised of an RFID sensor wherein the RFID sensor comprises, a memory chip, an antenna, and a sensing film wherein analytical fit coefficients are stored on the memory chip to allow calibration of the RFID sensor. Also provided are manufacturing or monitoring systems comprised of an RFID sensor wherein the RFID sensor comprises, a memory chip, an antenna, and a complementary sensor attached to the antenna where the complementary sensor in a pre-calibrated fashion predictably affects the impedance of the antenna. | 11-12-2009 |
20090289792 | DISPOSABLE SENSING DEVICE HAVING RADIO FREQUENCY BASED SENSOR - A sensing device for sensing one or more conditions inside a container is provided. The sensing device comprises a radio frequency based sensor; a support for positioning the sensor in operative proximity to the inside of the container, and a pick-up coil in operative association with the sensor. | 11-26-2009 |
20100007876 | HOLLOW-CORE WAVEGUIDE-BASED RAMAN SYSTEMS AND METHODS - Embodiments of the invention include a method for sensing. Other embodiments include a method for sensing molecules, for example, homonuclear diatomic molecules. The method may include transmitting light from a light source through a hollow-core wave-guiding device that exhibits a low attenuation at predetermined operating optical frequencies; introducing a gaseous medium between the light source and the hollow-core wave-guiding device; and detecting molecules within the gas. | 01-14-2010 |
20100073135 | SENSORS HAVING GAP BASED SENSING DEVICES AND METHODS OF MAKING AND USING THE SAME - A sensor is provided. The sensor comprises at least one sensing device comprising a first electrode and a second electrode, and a gap defined as a distance between one or more facing inner surfaces of the first and second electrodes, wherein the gap distance at least in part determines a threshold of one or more sensed parameters, and an antenna in operative association with the sensing device. | 03-25-2010 |
20100084573 | DETECTOR SYSTEM FOR UNIDENTIFIED SUBSTANCES - Disclosed herein is a detection system for identifying an unidentified substance in a sample, comprising light emitting sources, where at least one of the light emitting sources emits light in the infrared region; a circuit board; a trigger, that activates a pulse of electrons from the circuit board to the light emitting sources; a detector; and a central processing unit, where fluorescence generated from the unknown unidentified substance that is illuminated by light from the light emitting sources is collected in the detector and analyzed in the central processing unit. | 04-08-2010 |
20100134286 | RADIO FREQUENCY BASED SENSORS EMPLOYING ANALYTE RECOGNITION ELEMENT - A radio frequency based sensor is provided. The sensor comprises a radio frequency identification tag having a substrate, where the radio frequency identification tag generates an associated electromagnetic field. The sensor further includes an analyte recognition element in operative association with the substrate, where the analyte recognition element is capable of binding to a target analyte, and a signal amplification entity coupled to the analyte recognition element, where the signal amplification entity facilitates change in electromagnetic field in presence of the target analyte. | 06-03-2010 |
20100141273 | SYSTEMS AND METHODS FOR USING FERRITE ALIGNMENT KEYS IN WIRELESS REMOTE SENSORS - The present invention related to devices and methods for using ferrite alignment keys in wireless remote sensor assemblies. In one aspect, the invention provides wireless resonant sensor assemblies comprising a pick-up coil, a ferrite alignment key positioned in and extending from the pick-up coil, and wireless resonant sensor having a receiving element wherein the pick-up coil and the wireless resonant sensor align upon insertion of the ferrite alignment key into the receiving element. The ferrite alignment key may also be part of a resonant sensor such that insertion of a pick-up coil into a receiving element of the alignment key results in a configuration where the alignment key is positioned in and extended from the pick-up coil. Methods of measuring one or more parameters of a monitoring system are also provided. The insertion of the ferrite alignment key aligns the pick-up coil and wireless resonant sensor thereby increasing sensing of the wireless resonant sensor by the pick-up coil. | 06-10-2010 |
20100258745 | OPTICAL ARTICLE HAVING ANTI-THEFT FEATURE AND A SYSTEM AND METHOD FOR INHIBITING THEFT OF SAME - A system for altering a functionality of an optical article from a pre-activated state to an activated state, comprising an optical article comprising an optical data layer for storing data, an external radiation source for generating an external stimulus adapted to interact with the optical article, such interaction causing a change in optical accessibility of optically stored data, a directing material, wherein said directing material is for directing the external stimulus to selective portions of the optical article, thereby altering the functionality of the optical article from a pre-activated state to an activated state; a convertible element capable of responding to the external stimulus to irreversibly alter the optical article from the pre-activated state of functionality to the activated state of functionality, wherein said convertible element comprises a color-shift dye, a magnetic material, a thermo-chromic material, a magneto-optical material, a light scattering material, a phase-change material, dye aggregates, or combinations thereof. | 10-14-2010 |
20100268479 | SENSOR SYSTEM AND METHODS FOR ANALYTE DETECTION - A system for selectively determining at least two analytes, comprising at least one resonant sensor circuit comprising a sensing material that predictably affects the resonant complex impedance response of a sensor electrode, wherein the sensing material having at least two material properties that change upon exposure to two or more analytes; and a processor that generates a multivariate sensor response pattern that is based at least in part on a change in the two material properties of the sensing material and a sensing device and methods adapted to detect an analyte using the same sensor system. | 10-21-2010 |
20110012736 | METHODS AND SYSTEMS FOR SENSING UPON RADIATION EXPOSURE - A method for sensing physical, chemical, and biological characteristics of an environment is provided. The method comprises using a radio frequency identification (RFID) sensor component having a predetermined range of power initiation levels and having predetermined resonant circuit parameters comprising the steps of activating the RFID sensor component and determining whether a range of power levels, needed for activating the sensor component, is below the predetermined range of power initiation levels; sensing at least one of the physical, chemical, and biological characteristics of the environment; quantifying the sensed characteristic of the environment using one or more selected resonant parameters, wherein the selection of parameters is based in part on the range of power levels needed to activate the sensor. | 01-20-2011 |
20110101996 | METHOD AND SYSTEM FOR PERFORMANCE ENHANCEMENT OF RESONANT SENSORS - The present invention related to methods and systems for simultaneously sensing two or more environmental parameters of a sample. Included is an inductor-capacitor-resistor (LCR) resonator sensor and a pick up coil in operative association with the LCR resonator sensor wherein viscoelastic changes in the sensing film cause displacement of the antenna relative to the pick up coil. | 05-05-2011 |
20110210271 | Detector System For Unidentified Substances - Disclosed herein is a detection system for identifying an unidentified substance in a sample, comprising a light emitting source; a circuit board; a trigger, that activates a pulse of electrons from the circuit board to the light emitting source such that the light emitting source emits light; a detector for collecting light from the unidentified substance; and a central processing unit for analyzing the collected light to identify the unidentified substance. | 09-01-2011 |
20110320142 | TEMPERATURE INDEPENDENT PRESSURE SENSOR AND ASSOCIATED METHODS THEREOF - A temperature independent pressure sensor for selectively determining pressure is provided. The sensor comprises a resonance sensor circuit, a pressure sensitive component disposed on the sensor circuit, and an electromagnetic field modulator. A temperature independent pressure sensor system comprises a resonance sensor circuit, a pressure sensitive component disposed on the sensor circuit, an electromagnetic field modulator, and a processor that generates a multivariate analysis of sensor response pattern that is based on a change in an environmental pressure of the sensor system. A method of detecting a pressure response pattern in a temperature independent manner is also provided. | 12-29-2011 |
20120001730 | METHODS AND SYSTEMS FOR INTEGRATED INTERROGATION OF RFID SENSORS - An integrated interrogator for a RFID sensor is provided. The integrated interrogator comprises a digital reader in communication with the RFID sensor, an impedance reader in communication with the RFID sensor, and one or more controllers that coordinate actions of the digital reader and the impedance reader. | 01-05-2012 |
20120004851 | FIELD-PORTABLE IMPEDANCE READER AND METHODS OF MAKING THE SAME - A field-portable impedance reader is provided. The impedance reader comprises a reader antenna, an impedance compensator, a calibrator, and a synchronous sampler. The impedance reader further comprises a digital processor that receives and processes signals from the synchronous sampler. Further, a wireless system comprising the impedance reader of the invention is provided. | 01-05-2012 |
20120114089 | Apparatus for Detecting Contaminants in a Liquid and a System for Use Thereof - Disclosed herein are apparatus and methods for detecting and quantifying contaminants in aqueous solutions. In one embodiment, an apparatus for the detection of contaminants within a liquid comprises a sensor and a controller. The sensor comprises a film and a transducer configured such that, during use, a first surface of the transducer is in fluid communication with a liquid, and the film is disposed between the first surface and the liquid. The film can be a polymeric material capable of hindering the transport of a non-desired species therethrough. The controller is in operational communication to the transducer, and is configured to determine the concentration of contaminants within the liquid. | 05-10-2012 |
20120116683 | HIGHLY SELECTIVE CHEMICAL AND BIOLOGICAL SENSORS - Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g. 10×, 1,000,000×) compared to other components in the mixture. | 05-10-2012 |
20120161787 | TEMPERATURE-INDEPENDENT CHEMICAL AND BIOLOGICAL SENSORS - Methods and sensors for selective fluid sensing are provided. A sensor includes a resonant inductor-capacitor-resistor (LCR) circuit and a sensing material disposed over a sensing region. The sensing region comprises at least a portion of the LCR circuit. Temperature-dependent response coefficients of inductance L, capacitance C, and resistance R properties of the LCR circuit and the sensing material are at least approximately 5 percent different from one another. The difference in the temperature-dependent response coefficients of the properties of the LCR circuit and the sensing material enables the sensor to selectively detect analyte fluids from an analyzed fluid mixture substantially independent of temperature. | 06-28-2012 |
20120166095 | HIGHLY SELECTIVE CHEMICAL AND BIOLOGICAL SENSORS - Methods and sensors for selective fluid sensing are provided. A sensor includes a resonant inductor-capacitor-resistor (LCR) circuit and a sensing material disposed over the LCR circuit. The sensing material includes a coordination compound of a ligand and a metal nanoparticle. The coordination compound has the formula: (X) | 06-28-2012 |
20120235690 | METHODS FOR ANALYTE DETECTION - A method is provided for selectively detecting the presence and concentration of at least four analytes in a mixture. In certain embodiments, the method comprises contacting a single sensor with the mixture of analytes, wherein the sensor comprises at least one resonant sensor circuit comprising a sensing material that comprises at least two material properties that change in the presence of four or more analytes in their mixtures, and generating a multivariate sensor response pattern. The methods disclosed herein further optionally comprise performing analyte classification and analyte quantitation. Methods for selectively detecting the concentration of at least one analyte in a mixture further comprising at least one interference are also described in the instant application. | 09-20-2012 |
20130052084 | CHEMICAL AND BIOLOGICAL SENSORS, SYSTEMS AND METHODS BASED ON RADIO FREQUENCY IDENTIFICATION - An embodiment of the invention described herein is directed to a detection system utilizing at least one radiofrequency identification (RFID) sensor comprising: an RFID sensor comprising: a substrate; an antenna; a sensor material selected to be sensitive to one of chemical or biological environment; and a reader, wherein said reader is configured to measure a signal in the form of a complex impedance from said RFID tag wherein said signal comprises a plurality of frequencies and a frequency shift of the maximum of the imaginary part of the complex impedance, a frequency shift of the minimum of the imaginary part of the complex impedance, a frequency shift of the maximum of the real part of the complex impedance, and changes in magnitude of the real part of the complex impedance; and, wherein said complex impedance is related to a nature and a concentration of analyte species derived from multivariate analysis. | 02-28-2013 |
20130135617 | PLASMONIC OPTICAL TRANSDUCER - A transducer includes a source of electromagnetic radiation, a substrate having a plurality of flow through passages and a receiver. The plurality of nanoparticles is disposed on the substrate and includes a material having a dielectric constant being arranged to support a photonically excited Plasmon in response to electromagnetic radiation from the source. The receiver measures the electromagnetic radiation and is disposed in optical communication with the substrate. | 05-30-2013 |
20130154847 | SYSTEM AND METHOD FOR MONITORING DOWN-HOLE FLUIDS - In one aspect the present invention provides a down-hole monitoring system, comprising one or more pieces of down-hole equipment, for example a down-hole logging tool, and at least one resonant sensor for obtaining physical and chemical parameters of a down-hole fluid in proximity to the sensor. In another aspect, the present invention provides a method for detecting material properties of a down-hole fluid, the method comprising placing a resonant LCR sensor within a piece of down-hole equipment, taking sensor readings down-hole, transmitting the sensor readings to a reader device, and analyzing the sensor readings. | 06-20-2013 |
20140002111 | RESONANT SENSOR AND AN ASSOCIATED SENSING METHOD | 01-02-2014 |
20140019067 | TEMPERATURE-INDEPENDENT CHEMICAL AND BIOLOGICAL SENSORS - Methods and sensors for selective fluid sensing are provided. A sensor includes a resonant inductor-capacitor-resistor (LCR) circuit and a sensing material disposed over a sensing region. The sensing region comprises at least a portion of the LCR circuit. Temperature-dependent response coefficients of inductance L, capacitance C, and resistance R properties of the LCR circuit and the sensing material are at least approximately 5 percent different from one another. The difference in the temperature-dependent response coefficients of the properties of the LCR circuit and the sensing material enables the sensor to selectively detect analyte fluids from an analyzed fluid mixture substantially independent of temperature. | 01-16-2014 |
20140025313 | HIGHLY SELECTIVE CHEMICAL AND BIOLOGICAL SENSORS - Methods and sensors for selective fluid sensing are provided. Each sensor includes a resonant inductor-capacitor-resistor (LCR) sensor that is coated with a sensing material. In order to collect data, an impedance spectrum is acquired over a relatively narrow frequency range, such as the resonant frequency range of the LCR circuit. A multivariate signature may be calculated from the acquired spectrum to discern the presence of certain fluids and/or fluid mixtures. The presence of fluids is detected by measuring the changes in dielectric, dimensional, resistance, charge transfer, and other changes in the properties of the materials employed by observing the changes in the resonant electronic properties of the circuit. By using a mathematical procedure, such as principal components analysis (PCA) and others, multiple fluids and mixtures can be detected in the presence of one another, even in a high humidity environment or an environment wherein one or more fluids has a substantially higher concentration (e.g. 10×, 1,000,000×) compared to other components in the mixture. | 01-23-2014 |
20140028327 | METHOD FOR SENSOR READER CALIBRATION - In one embodiment a method for sensor reader calibration comprising: performing a calibration of a sensor reader wherein the calibration comprises open circuit calibration, a short circuit calibration, and a load circuit calibration, or any combination thereof in any succession; enabling connection of a pickup coil to the sensor reader to measure a sensor response; and applying a baseline correction to the sensor response, wherein the baseline correction is obtained utilizing measurements from the calibration step. In a further embodiment, a method for sensor response calibration incorporating environmental correction comprising: measuring a first resonance impedance spectrum of the sensor with a first applied power to the pickup coil; measuring a second resonance impedance spectrum of the sensor with a second applied power to the pickup coil; and applying a correction to the sensor response corresponding to the respective measured first and second resonance impedance spectrum to mitigate for environmental parameters. | 01-30-2014 |
20140028330 | METHOD AND SYSTEM FOR IMPROVED WIRELESS SENSING - In one embodiment, a RF sensor comprising a sensing antenna and a reference antenna, wherein a sensing material is disposed upon said sensing antenna and wherein the sensing antenna is configured to test for specific analyte by measurement of the resonant impedance spectra, and the reference antenna is configured to mitigate and correct for environmental parameters and positionn. In a further embodiment, a method for sensing comprising; utilizing an RF sensor, wherein the RF sensor comprises a sensing antenna and a reference antenna, wherein said RF sensor is configured to test for a specific analyte; and, measuring a resonant impedance spectra of the sensing antenna and reference antennaat multiple frequencies to provide a subsequent multivariate analysis of a signal response from the RF sensor. | 01-30-2014 |
20140091811 | SYSTEMS AND METHODS FOR MONITORING SENSORS - A method for multivariable measurements using a single-chip impedance analyzer includes providing a sensor, exposing the sensor to an environmental parameter, determining a complex impedance of the sensor over a measured spectral frequency range of the sensor, and monitoring at least three spectral parameters of the sensor. | 04-03-2014 |
20140095102 | SYSTEMS AND METHODS FOR MONITORING SENSORS - An impedance analyzer is provided. The analyzer includes a signal excitation generator comprising a digital to analog converter, where a transfer function of the digital to analog converter from digital to analog is programmable. The impedance analyzer further includes a receiver comprising a low noise amplifier (LNA) and an analog to digital converter (ADC), where the LNA is a current to voltage converter; where the programmable digital to analog transfer function is implemented by a direct digital synthesizer (DDS) and a voltage mode digital to analog converter, or a digital phase locked loop (PLL), or both. Further, a multivariable sensor node having an impedance analyzer is provided. Furthermore, a multivariable sensor network having a plurality of multivariable sensor nodes is provided. | 04-03-2014 |
20140182362 | SYSTEMS FOR ANALYSIS OF FLUIDS - A resonant sensor assembly includes a dielectric substrate having a sensing region. The sensor assembly further comprises a plurality of tuning elements operatively coupled to the sensing region, where the sensing region is coupled to the plurality of tuning elements to define a plurality of resonant circuits. | 07-03-2014 |
20140182363 | METHODS FOR ANALYSIS OF FLUIDS - A method for analyzing a sample includes providing a sensor assembly having a sensing region with a plurality of resonant circuits, and a plurality of tuning elements. The method further includes exposing the sensor assembly to an environment comprising the sample, and probing the sample with one or more frequencies generated by the sensor assembly. Furthermore, the method includes determining an impedance of a sensor response over a measured spectral frequency range of the sensor assembly, and relating measurement of impedance of the sensor assembly to at least one environmental property of the sample. | 07-03-2014 |
20150080226 | METHODS OF SELECTING BINDING-ELEMENTS AND USES THEREOF - Methods for selecting a binding-element are provided. The method comprised of different steps. A first mixture is formed using at least one target molecule and a plurality of oligomers, followed by incubating the first mixture to form a second mixture comprising at least one target-bound oligomer and at least one target-unbound oligomer. Then a first accelerator is added to cleave the target-unbound oligomer and the target-bound oligomer is separated from the target molecule. This is followed by addition of a second accelerator for ligation, and a third accelerator for amplification followed by sequencing and post sequence analysis to select the binding-element. | 03-19-2015 |