Priyesh
Priyesh Jain, Tampa, FL US
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20130065837 | INTEGRIN INTERACTION INHIBITORS FOR THE TREATMENT OF CANCER - Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically effective amount of the integrin interaction inhibitor. Data show that integrin interaction inhibitors act synergistically or additively interact with anti-proliferative agents such as doxorubicin, SAHA, arsenic trioxide, and etoposide. | 03-14-2013 |
20150017259 | INTEGRIN INTERACTION INHIBITORS FOR THE TREATMENT OF CANCER - Integrin interaction inhibitors using a beta-turn promoter are described herein. These peptides are useful in treating cancer, such as multiple myeloma, by administering a therapeutically effective amount of the integrin interaction inhibitor. Data show that integrin interaction inhibitors act synergistically or additively interact with anti-proliferative agents such as doxorubicin, SAHA, arsenic trioxide, and etoposide. | 01-15-2015 |
20150071918 | PEPTIDES FOR THE TREATMENT OF CANCER - The invention relates to novel cyclic compounds (cyclic peptides), linkers useful as beta-turn promoters in cyclic peptides, and methods for treatment of malignant cells in vitro or in vivo using one or more linear and cyclic peptides. The peptides can act as integrin interaction inhibitors and may be used in the treatment of cancers as monotherapies or in combination with other anti-cancer agents, such as proteasome inhibitors, inhibitors of autophagy, alkylating agents, MEK inhibitors, FAK/PYK2 inhibitors, and EGFR inhibitors. The invention further concerns a method of predicting the binding of a cyclic or linear HYD1 peptide to a cancer cell by assessing overexpression of biomarkers such as CD44, VLA-4 integrin, basigin, CD138 (syndecan 1), NCAM, ICAM1, ICAM3, and CD59. The invention further concerns a method of detecting one or more members of a complex comprising CD44, VLA-4 integrin, basigin, CD138 (syndecan 1), NCAM, ICAM1, ICAM3, and CD59, using a linear or cyclic HYD1 peptide bearing a detectable moiety. | 03-12-2015 |
20150105328 | PEPTOID-PEPTIDE HYBRIDS AND THEIR USE - The invention concerns peptoid-peptide hybrids that may act as protein interaction inhibitors (PPIIs). Another aspect of the invention concerns a method for treating a disorder (e.g., an oncologic disorder) in a human or animal subject, comprising administering an effective amount of a peptoid-peptide hybrid (a peptoid body) of the invention, or a composition comprising a peptoid-peptide hybrid, to the subject in need thereof. Another aspect of the subject invention concerns a method for killing or inhibiting the growth of cells (e.g., cancer cells or malaria-infected cells), comprising contacting a cancer cell in vitro or in vivo with an effective amount of a peptoid-peptide hybrid, or a composition comprising the peptoid-peptide hybrid. Another aspect of the invention concerns a method for producing a peptoid-peptide hybrid. | 04-16-2015 |
Priyesh Jayendrakumar Jani, Haryana IN
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20150210939 | HYDROTREATING COKER KEROSENE WITH A SEPARATE TRIM REACTOR - A process for hydrotreating coker kerosene is described. Instead of a post treat reactor, a smaller trim reactor zone which operates at a lower pressure than the post treat reactor is used downstream of the product stripper. The trim reactor uses a noble metal catalyst to reduce the BI of the stripped product to less than about 150, and desirably in the range of about 50 to about 100. | 07-30-2015 |
Priyesh Kumar, Bangalore IN
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20140033198 | EXTENSIBLE DISTRIBUTION/UPDATE ARCHITECTURE - Methods and systems to install a player to process content data are disclosed. In some embodiments, a method includes launching a content access manager on a user device to read metadata containing compatible player data, determine whether a compatible player able to access the content data is installed on the user device, and if not, to install a compatible player. Other embodiments involve receiving content data and data about one or more compatible players able to access the content data, generating the metadata using the data about one or more compatible players, and distributing the content data, the metadata, and the content access manager in a transmittable unit. Additional apparatus, systems, and methods are disclosed. | 01-30-2014 |
Priyesh Padmavilasom, Newcastle, WA US
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20140325470 | METHOD AND SYSTEM FOR PLATFORM-INDEPENDENT APPLICATION DEVELOPMENT - A non-transitory computer-readable medium having instructions that when executed cause the implementation of a method is disclosed herein. The medium has instructions for facilitating the execution of at least a first hybrid application on a first device, the first hybrid application comprising commands related to platform-specific functionality and platform-independent functionality of the first device. The method includes initializing a loosely-coupled native engine configured to receive commands from the first hybrid application and to facilitate platform-specific functionality on the first device. The loosely-coupled native engine comprises a webserver module. The method includes receiving commands from the first hybrid application, wherein at least one of the commands comprises a device command to be converted to a corresponding platform-specific code prior to execution of the platform-specific code. And the method includes creating a handler to serve the device command and facilitate execution of the corresponding platform-specific code. | 10-30-2014 |
Priyesh Vijayakar, Maloja IN
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20140163241 | NOVEL CRYSTALLINE FORMS - The present invention relates to two novel crystalline forms of zofenopril calcium, to processes for their preparation and their use in pharmaceutical compositions. | 06-12-2014 |
Priyesh Vijayakar, Maharashtra IN
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20140378523 | NOVEL CRYSTALLINE FORMS OF ZOFENOPRIL CALCIUM - The present invention relates to two novel crystalline forms of zofenopril calcium, to processes for their preparation and their use in pharmaceutical compositions. | 12-25-2014 |
Priyesh Vijaykar, Hyderabad IN
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20140275551 | PROCESS FOR THE PREPARATION OF ROFLUMILAST - The present invention relates to an improved process for the preparation of Roflumilast. The present invention also relates to crystalline Form-I of Roflumilast. | 09-18-2014 |