Patent application number | Description | Published |
20090093475 | Oxo-substituted imidazo[1,2b]pyridazines, their preparation and use as pharmaceuticals - The invention relates to novel inhibitors of kinases of the general formula (I): | 04-09-2009 |
20100048891 | METASUBSTITUTED THIAZOLIDINONES, THEIR MANUFACTURE AND USE AS A DRUG - Thiazolidinones of general formula (I) | 02-25-2010 |
20100105744 | SUBSTITUTED 7-SULFANYLMETHYL-, 7-SULFINYLMETHYL- AND 7-SULFONYLMETHYLINDOLES AND THE USE THEREOF - The present application relates to novel 7-sulfanylmethyl-, 7-sulfinylmethyl- and 7-sulfonylmethylindole derivatives, processes for the preparation thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases, and the use thereof for the manufacture of medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders. | 04-29-2010 |
20110201564 | SUBSTITUTED 7-SULFANYLMETHYL, 7-SULFINYLMETHYL AND 7-SULFONYLMETHYL INDOLES AND USE THEREOF - The present application relates to novel 7-sulfanylmethyl-, 7-sulfinylmethyl- and 7-sulfonylmethylindole derivatives, processes for the preparation thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases, and the use thereof for the manufacture of medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders. | 08-18-2011 |
20130156756 | Substituted Triazolopyridines - The present invention relates to substituted triazolopyridine compounds of general formula (I): in which R | 06-20-2013 |
20140135323 | OXO-SUBSTITUTED IMIDAZO[1,2B]PYRIDAZINES, THEIR PREPARATION AND USE AS PHARMACEUTICALS - The invention relates to novel inhibitors of kinases of the general formula (I): | 05-15-2014 |
Patent application number | Description | Published |
20090005786 | Bone hole measuring device - A measuring device for measuring the length of a through-hole in a bone has an elongated hollow sleeve preferably having an outer cross-section adapted to a cross-section of the through-hole and having an opening at its distal extremity. The measuring device further comprises a rod having a hook-shaped end at its distal extremity. The rod is at least partly housed within the hollow sleeve and is slidable with respect to the sleeve along its longitudinal axis. The sleeve and the rod are designed such that, when the rod is slid to a distal position of the sleeve, the hook-end can be displaced such as to protrude through the opening of the sleeve and laterally over the lateral outer surface of the sleeve. When the rod is slid to a proximal position of the sleeve, the rod no longer protrudes laterally over the outer surface of the sleeve. | 01-01-2009 |
20130190569 | SURGICAL INSTRUMENT FOR POSITIONING A SLEEVE - A surgical instrument for positioning a sleeve is presented. The surgical instrument comprises a shaft, a handle connected to one end of the shaft, a sleeve holder connected to the opposite end of the shaft and defining a space in which the sleeve is to be positioned. The surgical instrument further comprises a locking element adapted to protrude into the space for engagement of the sleeve and a magnet adapted to force the locking element into the space by a magnetic force. | 07-25-2013 |
20130190570 | GUIDE SLEEVE FOR SUPRAPATELLAR SURGERY - A tissue protection sleeve for use in suprapatellar surgery is provided. The sleeve has a first end, a second end, an inner surface and an outer surface. The sleeve further comprises at least two open grooves that extend along the inner surface from the first end to the second end. The grooves are adapted to accommodate elongated fixation elements inserted into a tibia. A drill guide sleeve and a trocar for inserting a guide wire are also provided and can be accommodated by the tissue protection sleeve. | 07-25-2013 |
20130274811 | TARGETING DEVICE FOR ORTHOPEDIC IMPLANTS - A medical system includes parts used in a method for detachably establishing a spatial orientation between a body implant and an aiming device. A positioning arm being connected to the aiming device and an adaptor device being connected to or integrally formed with a bone stabilizing plate are hooked into each other. This is accomplished by means of an engaging element of the positioning arm, which engaging element is designed such that it may be coupled with an attachment element of the adaptor device. Further, there is provided a snapping mechanism which is designed to automatically engage in an interlocking element of the adaptor device, when the positioning arm, when hooked into the adaptor device, is rotated relative to the adaptor device towards a final angular position. | 10-17-2013 |
20130325010 | BONE FASTENER AND METHOD OF MANUFACTURING THE SAME - A bone fastener for use in orthopaedic surgery for anchoring an intramedullary nail to bone has a shaft with a front region and a rear region adjacent to the front region. The rear region has one or more explantation grooves helically arranged for facilitating the explantation of the bone fastener. Two axially spaced apart grooves or groove sections are separated by a flat shaft portion defining an outside diameter of the rear region, wherein the rear region has a core diameter greater than a core diameter of the front region. | 12-05-2013 |
20140364859 | TARGETING ADJUSTMENT - A targeting system for aligning an axis of a targeting sleeve and a bore in a distal end portion of an intramedullary nail is proposed, the targeting device comprising a distal targeting arm with a first end being configured to be coupled to a trailing end of an intramedullary nail, an adjusting device, the adjusting device being configured to be coupled to the distal targeting arm. The adjusting device may comprise an adjusting element and a nail follower including two targeting holes each being configured to receive a sleeve assembly. The adjusting element may cooperate with the nail follower such that the positions of the two targeting holes are adjustable so as to correspond to respective locking holes at a leading end of the intramedullary nail, even when the nail is bent. | 12-11-2014 |
20140364863 | SLEEVE CLAMP - A sleeve clamp has a body with a through bore for receiving a sleeve, and a clamping element. The clamping element includes a clamping edge and may be arranged at the body so as to be movable between two positions, i.e. a neutral position and a deflected position. In the neural position, the clamping edge protrudes laterally into a lumen which is occupied by the sleeve when the sleeve is received in the through bore. In the deflected position, the clamping element may be elastically deformed and the clamping edge does not protrude into the lumen which is occupied by the sleeve when the sleeve is received in the through bore. | 12-11-2014 |