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Prabhakar, US
Aparna Prabhakar, White Plains, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100276277 | ELECTROCHEMICAL LIQUID CELL APPARATUS - An electrochemical cell apparatus is disclosed where the cell has a chamber for containing an electrolyte. The chamber is situated between a bottom and a top substrate. One or more bottom windows are in the bottom substrate and one or more top windows are in the top substrate. Each window has a window cover facing the chamber. The top window and bottom window each have a portion in alignment so that an electron beam passes through both respective portions. A spacer is deposited between the top and bottom substrate and forming walls surrounding the chamber. Two or more electrodes, each having an interior portion that is within the chamber and electrically continuous with an exterior portion external to the chamber, are located on the chamber side of the bottom substrate. | 11-04-2010 |
Aparna Prabhakar, North White Plains, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20110266539 | High Performance Compliant Wafer Test Probe - An electrical connection includes a first electrical contact made of electrically conductive material. The first electrical contact is formed with a depression therein. Also included are a deformable pad, having a Young's modulus of less than 1,000,000 psi, which bears on the first contact; and a second electrical contact, made of electrically conductive material, which contacts the first electrical contact and is at least partially received into the depression. The deformable pad at least partially causes at least one lateral force on the first electrical contact, so as to induce the first electrical contact to make an electrical connection with the second electrical contact. An array of such contacts is also contemplated, as is an array of cantilevered contacts, which may or may not have depressions, and which are supported by at least one elastomeric pad, having a Young's modulus of less 72,500 psi. | 11-03-2011 |
| 20110290402 | Handler Attachment for Integrated Circuit Fabrication - A method for attaching a handler to a wafer, the wafer comprising an integrated circuit (IC), includes forming a layer of an adhesive on the wafer, the adhesive comprising a polyimide-based polymer configured to withstand processing at a temperature of over about 280° C.; and adhering a handler to the wafer using the layer of adhesive. A system for attaching a handler to a wafer, the wafer comprising IC, includes a layer of an adhesive located on the wafer, the adhesive comprising a polyimide-based polymer configured to withstand processing at a temperature of over about 280° C.; and a handler adhered to the wafer using the layer of adhesive. | 12-01-2011 |
| 20110290406 | Laser Ablation for Integrated Circuit Fabrication - A method for releasing a handler from a wafer, the wafer comprising an integrated circuit (IC) includes attaching the handler to the wafer using an adhesive comprising a polymer; performing edge processing to remove an excess portion of the adhesive from an edge of the handler and wafer; ablating the adhesive through the handler using a laser, wherein a wavelength of the laser is selected based on the transparency of the handler material; and separating the handler from the wafer. A system for releasing a handler from a wafer, the wafer comprising an IC includes a handler attached to a wafer using an adhesive comprising a polymer; an edge processing module, the edge processing module configured to remove an excess portion of the adhesive from the edge of the handler and wafer; and a laser, the laser configured to ablate the adhesive through the handler. | 12-01-2011 |
| 20110290413 | Laser Ablation of Adhesive for Integrated Circuit Fabrication - A method for releasing a handler from a wafer, the wafer comprising an integrated circuit (IC), includes attaching the handler to the wafer using an adhesive comprising a thermoset polymer, the handler comprising a material that is transparent in a wavelength range of about 193 nanometers (nm) to about 400 nm; ablating the adhesive through the handler using a laser, wherein a wavelength of the laser is selected based on the transparency of the handler material; and separating the handler from the wafer. | 12-01-2011 |
| 20120045853 | SER Testing for an IC Chip Using Hot Underfill - A method for detecting soft errors in an integrated circuit (IC) due to transient-particle emission, the IC comprising at least one chip and a substrate includes mixing an epoxy with a radioactive source to form a hot underfill (HUF); underfilling the chip with the HUF; sealing the underfilled chip; measuring a radioactivity of the HUF at an edge of the chip; measuring the radioactivity of the HUF on a test coupon; testing the IC for soft errors by determining a current radioactivity of the HUF at the time of testing based on the measured radioactivity; and after the expiration of a radioactive decay period of the radioactive source, using the IC in a computing device by a user. | 02-23-2012 |
| 20120138145 | STRUCTURE AND DESIGN OF CONCENTRATOR SOLAR CELL ASSEMBLY RECEIVER SUBSTRATE - A substrate has a top side and a bottom side. A solar cell is secured to the top side of the substrate and has an anode and a cathode. A heat transfer element is secured to the bottom side of the substrate. An anode pad is formed on the top side of the substrate and is coupled to the anode of the solar cell; similarly, a cathode pad is formed on the top side of the substrate and is coupled to the cathode of the solar cell. The substrate coefficient of thermal expansion and the solar cell coefficient of thermal expansion match within plus or minus ten parts per million per degree C. | 06-07-2012 |
| 20120329295 | High Performance Compliant Wafer Test Probe - An electrical connection includes a first electrical contact made of electrically conductive material. The first electrical contact is formed with a depression therein. Also included are a deformable pad, having a Young's modulus of less than 1,000,000 psi, which bears on the first contact; and a second electrical contact, made of electrically conductive material, which contacts the first electrical contact and is at least partially received into the depression. The deformable pad at least partially causes at least one lateral force on the first electrical contact, so as to induce the first electrical contact to make an electrical connection with the second electrical contact. An array of such contacts is also contemplated, as is an array of cantilevered contacts, which may or may not have depressions, and which are supported by at least one elastomeric pad, having a Young's modulus of less 72,500 psi. | 12-27-2012 |
Bellur S. Prabhakar, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20110117627 | REGULATION OF APOPTOSIS BY NEURAL SPECIFIC SPLICE VARIANTS OF IG20 - Pro-apoptotic signaling caused by down-modulation of KIAA0358 or expression of IG20-SV4 effectively induces spontaneous apoptosis and sensitization to TNFα-induced apoptosis in neuroblastoma cells. Methods and composition to enhance cell death in neuroblastoma are provided. Methods and compositions to reduce cell death in neurodegenerative disorders are provided. | 05-19-2011 |
Bellur S. Prabhakar, Oak Brook, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080233645 | Methods and Compositions of Ig20 and Denn-Sv Splice Variants - Methods and compositions relating to IG20 expression, splice variants of IG20, effects of endogenous DENN-SV function with respect to processes regulating cell proliferation, cell survival and cell death are disclosed. | 09-25-2008 |
| 20090075929 | IG20 SPLICE VARIANTS THERAPEUTICS FOR CANCER - Methods and compositions inhibit the growth of cancer cells by selectively down-regulating the expression of an IG20 splice variant including MADD. Specific knock-down of MADD splice variant resulted in the apoptosis of cancer cells. Interfering RNAs including small hairpin RNAs (shRNA) to down-regulate MADD expression in vivo are disclosed. Inhibition of MADD phosphorylation by Akt results in activation of cancer cell death. Down-regulation of MADD expression results in switching to apoptotic mode due to lack of MAPK activation upon TNF-α-based induction. | 03-19-2009 |
| 20090232854 | USES OF BISPECIFIC ANTIBODY COATED DENDRITIC CELLS PULSED WITH ANTIGENS AND GM-CSF IN IMMUNE REGULATION - GM-CSF administered before immunization exerted a sustained suppressive effect against the induction of myasthenia gravis (MG). This suppression was associated with lowered serum autoantibody levels, reduced T cell proliferative responses to AChR, and an expansion in the population of FoxP3+ regulatory T cells. Manipulating DCs to expand regulatory T cells is useful for the control of autoimmune diseases such as myasthenia gravis MG. | 09-17-2009 |
Bellur S. Prabhakar, Oakbrook, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20080248043 | Antibodies to SARS coronavirus - The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that specifically bind to human SARS-CoV S protein, and that function to neutralize SARS-CoV. The invention also relates to antibodies that are bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulins derived from human anti-SARS-CoV S protein antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of using the antibodies and compositions for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-SARS-CoV S protein antibodies. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention. | 10-09-2008 |
Jay Prabhakar, Bedford, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20080254846 | GAME PIECE ADVANCING SKILL GAME AND METHODS - A game piece advancing skill game having a base with a mole figure that extends upwardly through an opening in the base, and a tower having a bell at its upper end. Another mole character is mounted on the tower and the toy is adapted such that striking the mole character on the base causes the mole character on the tower to be advanced upwardly toward the bell by an amount proportional to the striking force applied to the character on the base. A toy mallet is provided for striking the mole character on the base. In addition, LEDs are provided at spaced intervals on the tower as designated by numerals | 10-16-2008 |
Karthir Prabhakar, Atlanta, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20120301105 | SYSTEMS AND METHODS FOR RETRIEVING CASUAL SETS OF EVENTS FROM UNSTRUCTURED SIGNALS - A method for providing improved performance in retrieving and classifying causal sets of events from an unstructured signal can comprise applying a temporal-causal analysis to the unstructured signal. The temporal-causal analysis can comprise representing the occurrence times of visual events from an unstructured signal as a set of point processes. An exemplary embodiment can comprise interpreting a set of visual codewords produced by a space-time-dictionary representation of the unstructured video sequence as the set of point processes. A nonparametric estimate of the cross-spectrum between pairs of point processes can be obtained. In an exemplary embodiment, a spectral version of the pairwise test for Granger causality can be applied to the nonparametric estimate to identify patterns of interactions between visual codewords and group them into semantically meaningful independent causal sets. The method can further comprise leveraging the segmentation achieved during temporal causal analysis to improve performance in categorizing causal sets. | 11-29-2012 |
Nanduri R. Prabhakar, Chicago, IL US
| Patent application number | Description | Published |
|---|---|---|
| 20130131028 | METHODS FOR TREATMENT OF SLEEP-RELATED BREATHING DISORDERS - Described herein are methods for modulation of the activity of the carotid body that afford therapeutic benefit for sleep-related breathing disorders and related conditions. | 05-23-2013 |
Prakash Prabhakar, Braintree, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100112570 | Genetic Markers for Weight Management and Methods of Use Thereof - This application relates to methods and tests that allow for the establishment of personalized weight-loss programs for a subject based upon the subject's metabolic genotype in key metabolic genes. Kits and methods are disclosed for determining a subject's metabolic genotype, which may be used to select an appropriate therapeutic/dietary regimen or lifestyle recommendation based upon the likelihood of a subject's responsiveness to certain diets and activity levels. Such a personalized weight-loss program will have obvious benefits (e.g., yield better results in terms of weight loss and weight maintenance) over traditional weight-loss programs that do not take into account genetic information. | 05-06-2010 |
| 20110008906 | Genetic Association of Polymorphisms in Perilipin (PLIN) Gene With Resistance to Weight Loss - Diagnostics and therapeutics for resistance to weight-loss, which are based upon the identification of a subject's PLIN polymorphisms, haplotype and genotype pattern, are described in this invention. | 01-13-2011 |
| 20130011841 | Genetic Association of Polymorphisms in Perilipin (PLIN) Gene With Resistance to Weight Loss - Diagnostics and therapeutics for resistance to weight-loss, which are based upon the identification of a subject's PLIN polymorphisms, haplotype and genotype pattern, are described in this invention. | 01-10-2013 |
Rajeev S. Prabhakar, Wilmington, DE US
| Patent application number | Description | Published |
|---|---|---|
| 20090007779 | METHOD AND SYSTEM OF PROVIDING CARBON DIOXIDE-ENRICHED GAS FOR GREENHOUSES - A feed gas is separated into a CO | 01-08-2009 |
| 20100275777 | Membrane-Based Process for CO2 Capture from Flue Gases Generated by Oxy-Combustion of Coal - Disclosed is a membrane-based method and system for treatment of flue gases from an oxy-combustion coal-fired boiler to recover approximately 90% (vol/vol) to approximately 95% (vol/vol) of the carbon dioxide in the flue gas and produce a carbon dioxide product having a carbon dioxide concentration of approximately 90% (vol/vol dry basis) to approximately 97% (vol/vol dry basis). | 11-04-2010 |
| 20110000261 | Low Maintenance Burner for Glass Forehearth - A burner recessed from a combustion space in a burner block adjacent the combustion space injects a secondary reactant (a second portion of a first reactant) around and upstream of a stream of a primary reactant (a first portion of the first reactant) and a stream of a second reactant in order to prevent or inhibit deposition of material from recirculating gases in the combustion space upon the burner. The first reactant is one of a fuel and an oxidant while the second reactant is the other of a fuel and an oxidant. The secondary stream may be injected from a continuous annulus formed in an outer body of the burner or from a plurality of radially spaced holes formed in the outer body. The primary stream is injected from one of an inner bore formed in an inner body of the burner and a reactant annulus defined between the inner and outer bodies while the second reactant is injected from the other of the inner bore and the reactant annulus. | 01-06-2011 |
| 20110183278 | Combustion Tool Comprising a Quarl Block and an Injector, Assembly of Said Tool and Furnace Equipped with Said Tool - The invention relates to a combustion tool including a quarl block made of refractory material, the quarl block defining a quarl exit and a passage between the entry surface and quarl block, said tool including an injector of oxidizer and/or fuel that extends through the passage and opens into the quarl block, and also including a sheath that surrounds the injector in the passage section. | 07-28-2011 |
| 20120009531 | DISTRIBUTED COMBUSTION PROCESS AND BURNER - During a heating phase, injection of a jet of fuel and oxidant (fuel annularly enshrouding oxidant or oxidant annularly enshrouding fuel) from a fuel-oxidant nozzle is combusted in a combustion space. During a transition from the heating phase to a distributed combustion phase, an amount of a secondary portion of either the fuel or oxidant is injected as a jet into the combustion space while the primary portion of that same reactant from the fuel-oxidant nozzle is decreased. At some point during the transition phase, a jet of actuating fluid is injected at an angle towards the jet of reactants from the fuel-oxidant nozzle and/or towards the jet of the secondary portion of reactant. The jet of primary portions of reactants and/or secondary portion of reactant is caused to be bent/deviated towards the other of the two jets. The staging of the secondary portion of reactant is increased until a desired degrees of staging and commencement of a distributed combustion phase are achieved. | 01-12-2012 |
| 20120009532 | DISTRIBUTED COMBUSTION PROCESS AND BURNER - During a heating phase, injection of a jet of fuel and oxidant (fuel annularly enshrouding oxidant or oxidant annularly enshrouding fuel) from a fuel-oxidant nozzle is combusted in a combustion space. During a transition from the heating phase to a distributed combustion phase, an amount of a secondary portion of either the fuel or oxidant is injected as a jet into the combustion space while the primary portion of that same reactant from the fuel-oxidant nozzle is decreased. At some point during the transition phase, a jet of actuating fluid is injected at an angle towards the jet of reactants from the fuel-oxidant nozzle and/or towards the jet of the secondary portion of reactant. The jet of primary portions of reactants and/or secondary portion of reactant is caused to be bent/deviated towards the other of the two jets. The staging of the secondary portion of reactant is increased until a desired degrees of staging and commencement of a distributed combustion phase are achieved. | 01-12-2012 |
| 20120171629 | Flameless Combustion Burner - A burner has a fuel/oxidant nozzles and a pair of dynamical lances spaced on either side thereof that inject a jet of fuel and primary oxidant along a fuel injection axis, and jets of secondary oxidant, respectively. Jets of actuating fluid impinge against the jets of secondary oxidant to fluidically angle the jets of secondary oxidant away from the fuel injection axis. The action of the angling away together with staging of the oxidant between primary and secondary oxidant injections allows achievement of distributed combustion conditions. | 07-05-2012 |
Sunil Prabhakar, West Lafayette, IN US
| Patent application number | Description | Published |
|---|---|---|
| 20120209822 | SYSTEM AND METHODS FOR ENSURING INTEGRITY, AUTHENTICITY, INDEMNITY, AND ASSURED PROVENANCE FOR UNTRUSTED, OUTSOURCED, OR CLOUD DATABASES - A system and methods for providing guarantees about faithful execution of databases that run under the control of an untrusted entity—such as a cloud computing service provider—that is different than the owner of the data and applications being outsourced; or runs on a server that may be compromised by unauthorized users. Specifically, the system and methods establishes that an untrusted database is being faithfully hosted and provides indemnity for the service provider from false claims, enabling the server to prove its innocence against untrue claims of faulty operation. The invention also provides assured provenance for all changes made to the database. | 08-16-2012 |
Vikas Prabhakar, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20080248080 | Decelluarlized Tissue Engineered Constructs and Tissues - New methods for producing tissue engineered constructs and engineered native tissues are disclosed. The methods include producing a tissue engineered construct by growing cells in vitro on a substrate and then decellularizing the construct to produce a decellularized construct consisting largely of extracellular matrix components. The construct can be used immediately or stored until needed. The decellularized construct can be used for further tissue engineering, which may include seeding the construct with cells obtained from the intended recipient of the construct. During any of the growth phases required for production of the construct, the developing construct may be subjected to various tissue engineering steps such as application of mechanical stimuli including pulsatile forces. The methods also include producing an engineered native tissue by harvesting tissue from an animal or human, performing one or more tissue engineering steps on the tissue, and subjecting the tissue to decellularization. The decellularized, engineered native tissue may then be subjected to further tissue engineering steps. | 10-09-2008 |
| 20120135049 | Decellularized tissue engineered constructs and tissues - Methods for producing tissue engineered constructs and engineered native tissues include producing a tissue engineered construct by growing cells in vitro on a substrate and then decellularizing the construct to produce a decellularized construct consisting largely of extracellular matrix components. The construct can be used immediately or stored until needed. The decellularized construct can be used for further tissue engineering, which may include seeding the construct with cells obtained from the intended recipient of the construct. During any of the growth phases required for production of the construct, the developing construct may be subjected to various tissue engineering steps such as application of mechanical stimuli including pulsatile forces. | 05-31-2012 |