Pohl, US
Andrew Peter Pohl, Hampton, VA US
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20110091702 | Composite Products and Methods for Manufacturing - The present disclosure relates to a method for forming a composite product. The method involves compressing a semi-hydraulic medium within a compression cell thereby causing the semi-hydraulic medium to fill voids in the compression cell and to encapsulate an incompressible element within the compression cell. The present disclosure also relates to composite products made in accordance with the above method. | 04-21-2011 |
20110219921 | Cutting System - A cutting system for cutting natural or composite products is disclosed. The cutting system includes a fixed shear cutting blade having a cutting edge that faces upwardly. The cutting system also includes a movable ram positioned above the cutting edge. The movable ram can be moved upwardly and downwardly relative to the cutting edge. In use of the cutting system, a product desired to be cut is fed between the movable ram and the cutting edge of the cutting blade. By moving the movable ram downwardly toward the cutting blade, the product is compressed against the cutting blade thereby causing the cutting edge of the cutting blade to cut upwardly through the product. | 09-15-2011 |
Brad Pohl, Leander, TX US
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20100093476 | INFINITELY VARIABLE TRANSMISSIONS, CONTINUOUSLY VARIABLE TRANSMISSIONS, METHODS, ASSEMBLIES, SUBASSEMBLIES, AND COMPONENTS THEREFOR - Inventive embodiments are directed to components, subassemblies, systems, and/or methods for infinitely variable transmissions (IVT) having a variator provided with a plurality of tilting spherical planets. In one embodiment, a variator is provided with multiple planet arrays. In another embodiment, a hydraulic system is configured to control the transmission ratio of the IVT. Various inventive idler assemblies and planet-pivot arm assemblies can be used to facilitate adjusting the transmission speed ratio of an IVT. Embodiments of a transmission housing and bell housing are adapted to house components of an IVT and, in some embodiments, to cooperate with other components of the IVT to support operation and/or functionality of the IVT. Various related devices include embodiments of, for example, a control feedback mechanism, axial force generation and management mechanisms, a control valve integral with an input shaft, and a rotatable carrier configured to support planet-pivot arm assemblies. | 04-15-2010 |
20100093479 | CONTINUOUSLY VARIABLE TRANSMISSIONS AND METHODS THEREFOR - Inventive embodiments are directed to components, subassemblies, systems, and/or methods for continuously variable transmissions (CVT) having a variator provided with a plurality of tilting, traction planets and traction rings. In one embodiment, a variator is coupled to a rangebox to provide multiple operating modes. In another embodiment, a hydraulic system is configured to control the transmission ratio of the variator and the rangebox. Various inventive shift-cam-and-sun subassemblies can be used to facilitate shifting of the transmission ratio of a CVT. Embodiments of a transmission housing and bell housing are adapted to house components of a CVT and, in some embodiments, to cooperate with other components of the CVT to support operation and/or functionality of the CVT. Various related devices include embodiments of, for example, a pivot arm, a control feedback mechanism, axial force generation and management mechanisms, a control valve integral with an input shaft, a pivot pin hub, and a rotatable carrier configured to support planet-pivot arm assemblies. FIG. | 04-15-2010 |
20120115667 | CONTINUOUSLY VARIABLE TRANSMISSION - Disclosed embodiments are directed to components, subassemblies, systems, and/or methods for continuously variable transmissions (CVT). In one embodiment, a CVT has a number of spherical planets in contact with an idler. Various idler assemblies can be used to facilitate to improve durability, fatigue life, and efficiency of a CVT. In one embodiment, the idler assembly has two rolling elements having contact surfaces that are angled with respect to a longitudinal axis of the CVT. In some embodiments, a bearing is operably coupled between the first and second rolling elements. The bearing is configured to balance axial force between the first and second rolling elements. In one embodiment, the bearing is a ball bearing. In another embodiment, the bearing is an angular contact bearing. In yet other embodiments, needle roller bearings are employed. | 05-10-2012 |
20130143708 | INFINITELY VARIABLE TRANSMISSIONS, CONTINUOUSLY VARIABLE TRANSMISSIONS, METHODS, ASSEMBLIES, SUBASSEMBLIES, AND COMPONENTS THEREFOR - Inventive embodiments are directed to components, subassemblies, systems, and/or methods for infinitely variable transmissions (IVT) having a variator provided with a plurality of tilting spherical planets. In one embodiment, a variator is provided with multiple planet arrays. In another embodiment, a hydraulic system is configured to control the transmission ratio of the IVT. Various inventive idler assemblies and planet-pivot arm assemblies can be used to facilitate adjusting the transmission speed ratio of an IVT. Embodiments of a transmission housing and bell housing are adapted to house components of an IVT and, in some embodiments, to cooperate with other components of the IVT to support operation and/or functionality of the IVT. Various related devices include embodiments of, for example, a control feedback mechanism, axial force generation and management mechanisms, a control valve integral with an input shaft, and a rotatable carrier configured to support planet-pivot arm assemblies. | 06-06-2013 |
20140073470 | INFINITELY VARIABLE TRANSMISSIONS, CONTINUOUSLY VARIABLE TRANSMISSIONS, METHODS, ASSEMBLIES, SUBASSEMBLIES, AND COMPONENTS THEREFOR - Inventive embodiments are directed to components, subassemblies, systems, and/or methods for infinitely variable transmissions (IVT) having a variator provided with a plurality of tilting spherical planets. In one embodiment, a variator is provided with multiple planet arrays. In another embodiment, a hydraulic system is configured to control the transmission ratio of the IVT. Various inventive idler assemblies and planet-pivot arm assemblies can be used to facilitate adjusting the transmission speed ratio of an IVT. Embodiments of a transmission housing and bell housing are adapted to house components of an IVT and, in some embodiments, to cooperate with other components of the IVT to support operation and/or functionality of the IVT. Various related devices include embodiments of, for example, a control feedback mechanism, axial force generation and management mechanisms, a control valve integral with an input shaft, and a rotatable carrier configured to support planet-pivot arm assemblies. | 03-13-2014 |
Brad Philip Pohl, Leander, TX US
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20140262672 | VARIATOR BYPASS CLUTCH - A dog clutch operable to bypass a variator of a transmission is disclosed. The dog clutch includes a housing engaged with an input ring of the variator. The dog clutch also includes a piston engaged with the housing and movable from a first position in which the piston is disengaged from an output ring of the variator to a second position in which the piston is engaged with the output ring. The variator input ring and output ring are locked together when the dog clutch is in the second position to prevent the variator from producing continuously variable torque output. The variator is operable to produce continuously-variable torque output when the dog clutch is in the first position. | 09-18-2014 |
Brent Pohl, Timonium, MD US
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20150376562 | PROCESS TUBE AND CARRIER TRAY - The disclosure provides a system and method to safely and efficiently store and transport process tubes in a carrier tray comprising prior to and during amplification of nucleotides in the process tubes. The process tube disclosed includes a securement region having an annular ledge, a neck, and a protrusion. The securement region of the process tube can secure the process tube in a port of the carrier tray, but still allows the process tube to adjust or float in order to align the process tube into a rigid heater well of a thermal cycler. | 12-31-2015 |
Daniel Pohl, Stillwater, MN US
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20120115627 | ALIGNMENT OF GOLF PUTTERS WITH AN INTENDED PUTTING DIRECTION - High performance putters utilizing effective visual alignment features, enhanced feel, and excellent rolling characteristics. | 05-10-2012 |
Daniel Pohl, Princeton, IN US
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20140317776 | Maize Hybrid X18C108 - A novel maize variety designated X18C108 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X18C108 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X18C108 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X18C108, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X18C108. This invention further relates to methods for producing maize varieties derived from maize variety X18C108. | 10-23-2014 |
Douglas Alan Pohl, Davenport, IA US
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20150276298 | APPARATUSES AND METHODS TO IMPROVE AIR FLOW IN ON-THE-DOOR ICEMAKERS - On-the-door icemakers having improved air flow are disclosed. An example icemaker includes an ice mold configured to produce ice by removing heat from the ice mold using supplied cold air, and a shaped air flow redirection member disposed at least partially between the icemaker and the door to redirect at least a portion of the cold air away from the door toward the freezer compartment. | 10-01-2015 |
Jan Pohl, Tucker, GA US
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20100297666 | METHODS FOR DETERMINATION OF PROTEIN PHOSPHATASE ACTIVITY, AND USES IN PREDICTING THERAPEUTIC OUTCOMES - One aspect of the present disclosure encompasses methods for determining a protein kinase or phosphatase activity in a biological sample, comprising: contacting in a reaction mix a first test sample and a fluorescently-labeled peptide substrate capable of being modified by a protein phosphatase or a protein kinase, contacting the reaction mix with a TiO | 11-25-2010 |
20120308597 | SEROLOGIC CORRELATES OF PROTECTION AGAINST BACILLIS ANTHRACIS INFECTION - Regions of | 12-06-2012 |
20130122514 | METHODS FOR DETERMINATION OF PROTEIN PHOSPHATASE ACTIVITY, AND USES IN PREDICTING THERAPEUTIC OUTCOMES - One aspect of the present disclosure encompasses methods for determining a protein kinase or phosphatase activity in a biological sample, comprising: contacting in a reaction mix a first test sample and a fluorescently-labeled peptide substrate capable of being modified by a protein phosphatase or a protein kinase, contacting the reaction mix with a TiO | 05-16-2013 |
20140004139 | SEROLOGIC CORRELATES OF PROTECTION AGAINST BACILLIS ANTHRACIS INFECTION | 01-02-2014 |
20150246108 | SEROLOGIC CORRELATES OF PROTECTION AGAINST BACILLUS ANTHRACIS INFECTION - Regions of | 09-03-2015 |
Jeff Pohl, Fort Wayne, IN US
Patent application number | Description | Published |
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20090196585 | CHEMICAL HEATING ASSEMBLY - A chemical heating assembly includes a face plate, a chemical packet, a housing, a pair of electrical prongs carried by the housing, and a light assembly. The housing includes a first sliding arrangement and a first snap-fit arrangement, is connected to the face plate, and at least partially defines a pocket for the chemical packet. The light assembly includes a lamp, a second sliding arrangement engaged with the first sliding arrangement, and a second snap-fit arrangement coupled with the first snap-fit arrangement. The light assembly is mechanically connected to the housing and electrically connected with the pair of electrical prongs using the first and second sliding arrangements and the first and second snap-fit arrangements. | 08-06-2009 |
Jeffery Murray Pohl, Mapleton, IL US
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20090063223 | Systems and methods for assessing the level of conformance of a business process - A system for assessing a level of conformance of a business process with one more activities is disclosed. The disclosed system includes a memory to store program code and a process to assess the level of conformance. The assessment process includes storing a process standard, a business process classification, and a conformance scoring criterion, and determining a first conformance score for a first activity in the business process based on the conformance scoring criterion and the process standard. The assessment process further includes the steps of determining a second conformance score for a group of activities including the first activity based on one or more conformance scores including the first conformance score, determining a third conformance score based on the second conformance score, and assessing the level of conformance of the business process based on the third conformance score. | 03-05-2009 |
Jeffrey C. Pohl, Fort Wayne, IN US
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20100247372 | CHEMICAL DELIVERY ASSEMBLY - A chemical delivery system includes: a chemical storage device configured for emitting a volatilized chemical therefrom; a heating element which provides an exothermic chemical reaction; an at least substantially rigid housing element containing the heating element; a tray including a well, the well having an absence of a through-hole and defining a space which is slightly larger than the chemical storage device, the tray being attached to the housing element, the chemical storage device being mounted to the well, the heating element being in thermal communication with the chemical storage device via the well; a retainer attached to the well and including at least one hole configured for passing therethrough the volatilized chemical to an ambient environment, the retainer being configured for retaining the chemical storage device in the space; and a removable covering directly attached to the tray and covering the retainer and the well to thereby hermetically seal the chemical storage device within the space. | 09-30-2010 |
Jeffrey K. Pohl, Soddy Daisy, TN US
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20140188013 | METHOD AND APPARATUS FOR APPLYING NEUROMUSCULAR ELECTRICAL STIMULATION - A method and apparatus for applying neuromuscular electrical stimulation to an agonist/antagonist muscle pair to move a limb about a joint includes generating a first pattern of neuromuscular electrical stimulation pulses for output through a first channel to a first pair of electrodes and generating a second pattern of neuromuscular stimulation pulses for output through a second channel to a second pair of electrodes. The first pair of electrodes are attached to the agonist muscle of the agonist/antagonist muscle pair, and the second pair of electrodes are attached to the antagonist muscle. A first pattern of electrical stimulation pulses is transmitted through the first pair of electrodes to the agonist muscle at a first intensity level to initiate contraction of the agonist muscle, and then at a second intensity level which is less than the first intensity level to continue contraction of the agonist muscle. A second pattern of electrical stimulation pulses is transmitted through the second pair of electrodes to the antagonist muscle at a first intensity level to reduce the acceleration of the limb, and then at a second intensity level which is less than the first intensity level to regulate the movement of the limb. | 07-03-2014 |
J. Mark Pohl, Morristown, NJ US
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20140343026 | Dosage Form to Increase Prasterone Bioavailability - A way to formulate prasterone to both increase its oral bioavailability, and decrease the variability of its oral bioavailability. | 11-20-2014 |
J. Mark Pohl US
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20120276197 | Dosage Form to Increase Prasterone Bioavailability - A way to formulate prasterone to both increase its oral bioavailability, and decrease the variability of its oral bioavailability. | 11-01-2012 |
Kenneth Randall Pohl, Largo, FL US
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20130128261 | OPTICAL HAZARD AVOIDANCE AND METHOD - A source of light that could cause ocular damage within a given range from the source of light, such as a first laser, is accompanied by an optical hazard avoidance device, such as a second laser, that stimulates voluntary, involuntary, or both voluntary and involuntary responses, either physiological or behavioral or both physiological and behavioral, within one or more hazard zones, such as by inducing gaze aversion within the viewer. For example, a visible laser beam induces gaze aversion, pupil contraction or a combination of gaze aversion and pupil contraction, reducing the dose rate or exposure of the ocular tissue to damaging radiation from a primary source. In one example, the primary source is a UV Raman detector and the visible laser beam is selected to induce gaze aversion. | 05-23-2013 |
Kennth Pohl, Clearwater, FL US
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20130293882 | LASER DETECTION SYSTEM AND METHOD - A system comprises a processing system, a laser system, a telescope system, a detector system and optical systems operatively arranged such that the laser system may be capable of outputting multiple wavelengths to a common telescope system, and the detector system is capable of receiving signatures from the same telescope system, under the control of a control system. The processor system processes signals received from the detector system to determine substances identified by known signatures. For example, a plurality of detectors in the detector system each receive a range of wavelengths of the signatures received by the telescope system. For example, a variable beam diverger and variable beam expander operatively control expansion and divergence of the output the laser system. For example, a beam reducer and lenslet array may operatively transmit signatures via optical fiber bundle to one or more of the detectors. | 11-07-2013 |
Kilian M. Pohl, Santa Cruz, CA US
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20120197848 | VALIDATION OF INGESTED DATA - Methods and systems for validating ingested data are disclosed. In accordance with the methods and systems, data elements can be received for storage in slots of an individual descriptor in a storage medium. In addition, at least one validation test can be selected based on a weighting of the data elements that indicates a respective degree of importance of the data elements. The selected validation test or tests can be applied to the data elements stored in the slots to generate respective validation results. Further, a validation score indicating a sufficiency of the stored data elements can be generated based on the validation results. | 08-02-2012 |
20120330901 | VALIDATION OF INGESTED DATA - Methods and systems for validating ingested data are disclosed. In accordance with the methods and systems, data elements can be received for storage in slots of an individual descriptor in a storage medium. In addition, at least one validation test can be selected based on a weighting of the data elements that indicates a respective degree of importance of the data elements. The selected validation test or tests can be applied to the data elements stored in the slots to generate respective validation results. Further, a validation score indicating a sufficiency of the stored data elements can be generated based on the validation results. | 12-27-2012 |
Michael H. Pohl, Canton, MI US
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20080305907 | INPUT BRAKE ASSEMBLY - An input brake assembly is provided for selectively grounding a transmission input member. The packaging location of the input brake assembly does not interfere with, and thus still allows the option of providing a bypass clutch for a flex plate-type flywheel connecting the engine with the transmission input member. The input brake assembly includes a flywheel, preferably a flex plate, for transferring rotary torque between the engine and the transmission input member and a ring gear secured to the outer periphery of the flex plate. A pinion gear is axially movable into and out of meshing engagement with the ring gear. A grounding device is operatively connected to the pinion gear and is operable to prevent rotation of the pinion gear, thereby braking the flex plate as well as the transmission input member operatively connected thereto when the pinion gear is in meshing engagement with the ring gear. | 12-11-2008 |
Naomi Pohl, Morristown, NJ US
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20130333627 | Temperature-Controllable Aquaculture Apparatus - An inexpensive, easily manufactured aquaculture apparatus featuring a water temperature control feature, useful for studying the effect of water temperature changes on the viability of aquatic species. The apparatus is useful to, for example, study the potential effect of global warming and rising ocean water temperatures on various aquatic species. | 12-19-2013 |
Nicola Lucia Pohl, Ames, IA US
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20100159604 | AUTOMATED SOLUTION-PHASE ITERATIVE SYNTHESIS - The first method for iterative solution-phase biomolecule synthesis is described. The method requires only 3 or fewer equivalents of building block at each coupling cycle, and incorporates a FSPE step at the end of each coupling/deprotection sequence to eliminate most byproducts. | 06-24-2010 |
20110009612 | AUTOMATED SOLUTION-PHASE ITERATIVE SYNTHESIS - The first method for iterative solution-phase biomolecule synthesis is described. The method requires only 3 or fewer equivalents of building block at each coupling cycle, and incorporates a FSPE step at the end of each coupling/deprotection sequence to eliminate most byproducts. | 01-13-2011 |
Roderike Pohl, Sherman, CT US
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20090137455 | RAPID ACTING AND LONG ACTING INSULIN COMBINATION FORMULATIONS - An injectable formulation containing a combination of a rapid acting insulin and a long acting insulin has been developed wherein the pH of the rapid acting insulin is adjusted so that the long acting insulin, e.g. insulin glargine, remains soluble when they are mixed together. In the preferred embodiment, this injectable basal bolus insulin is administered before breakfast, provides adequate bolus insulin levels to cover the meal, does not produce hypoglycemia after the meal and provides adequate basal insulin for up to 24 hours. Lunch and dinner can be covered by two bolus injections of a fast acting, or a rapid acting or a very rapid acting insulin. Alternatively, through adjustment of the ratio of rapid acting insulin to long acting insulin, the long acting insulin may be shortened to a 12 hour formulation. This rapid and long acting blend is re-administered to the patient at dinner time, providing a safe and effective basal insulin level until morning. As a result, a patient using intensive insulin therapy should only inject three, rather than four, times a day. | 05-28-2009 |
20090175840 | INSULIN FORMULATIONS FOR INSULIN RELEASE AS A FUNCTION OF TISSUE GLUCOSE LEVELS - Injectable insulin formulations that are capable of modifying the amount of insulin released based on the patient's tissue glucose levels, methods for making and using these formulations are described herein. The formulation may be administered via subcutaneous, intradermal or intramuscular administration. In one preferred embodiment, the formulations are administered via subcutaneous injection. The formulations contain insulin, an oxidizing agent or enzyme and a reducing agent or enzyme, a diluent and optionally one or more thickening agents. If a thickening agent is present in the formulation, the thickening agent increases the viscosity of the formulation following administration. Preferably the formulation contains an insulin, a diluent, glucose oxidase and peroxidase. Following administration to a patient, the insulin is released from the formulations as a function of the patient's tissue glucose level, which in turn maintains the patient's blood glucose level within an optimum range. The formulation is often referred to as a “smart” formulation since it modifies its release rate of insulin according to the patient's needs at a particular time. In a preferred embodiment, the formulation is designed to release insulin into the systemic circulation over time with a basal release profile following injection in a patient. In another embodiment, the formulation is designed to release insulin into the systemic circulation over time with a non-basal release profile following injection in a patient, such as a regular human insulin release profile or a prandial release profile. | 07-09-2009 |
20100069292 | INSULIN WITH A BASAL RELEASE PROFILE - A clear basal insulin formulation composed of insulin (preferably human recombinant insulin), buffering agents, precipitating agents, and/or stabilizing agents for subcutaneous, intradermal or intramuscular administration. The formulation is designed to form a precipitate of insulin following injection, creating a slow releasing “basal insulin” over a period of 12 to 24 hours, which can be varied by compositional changes to tailor the release profile to the needs of the individual diabetic patient | 03-18-2010 |
20100227795 | INSULIN FORMULATIONS FOR RAPID UPTAKE - Injectable insulin formulations with improved stability and rapid onset of action are described herein. The formulations may be for subcutaneous, intradermal or intramuscular administration. In the preferred embodiment, the formulations are administered via subcutaneous injection. The formulations contain insulin in combination with a chelator and dissolution agent, and optionally additional excipients. In the preferred embodiment, the formulation contains human insulin, a zinc chelator such as EDTA and a dissolution agent such as citric acid or sodium citrate. These formulations are rapidly absorbed into the blood stream when administered by subcutaneous injection. In the preferred embodiment, the insulin is provided as a clear liquid, neutral pH, in a multi-use sterile vial. In an alternative embodiment, the insulin is provided as a powder in a sterile vial. This is mixed with a diluent containing a pharmaceutically acceptable carrier, such as water, a zinc chelator such as EDTA and a dissolution agent such as citric acid shortly before or at the time of administration. In another embodiment, the insulin is stored as a frozen mixture, ready for use upon thawing. | 09-09-2010 |
20110097386 | STABILIZED GLUCAGON SOLUTIONS - A formulation composed of a sugar such as glucose and a surfactant such as myristoyl lysophosphocholine (LMPC) has been designed to stabilize both hydrophilic and hydrophobic portions of the glucagon molecule, under prolonged physiological conditions, in a formulation that is sufficiently similar to the pH and osmolarity of plasma so as not to induce or to minimize site irritation. The combination of a simple sugar and an surfactant stabilizes the glucagon molecule in an aqueous solution for seven days at 37° C. | 04-28-2011 |
20110237510 | STABILIZED GLUCAGON SOLUTIONS - A formulation composed of a sugar such as glucose and a surfactant such as myristoyl lysophosphocholine (LMPC) has been designed to stabilize both hydrophilic and hydrophobic portions of the glucagon molecule, under prolonged physiological conditions, in a formulation that is sufficiently similar to the pH and osmolarity of plasma so as not to induce or to minimize site irritation. The combination of a simple sugar and an surfactant stabilizes the glucagon molecule in an aqueous solution for seven days at 37° C. | 09-29-2011 |
20110281790 | INSULIN WITH A STABLE BASAL RELEASE PROFILE - A basal insulin formulation composed of insulin, preferably insulin glargine, injectable zinc and injectable iron compounds as precipitating and/or stabilizing agents has been developed for subcutaneous, intradermal or intramuscular administration. The formulation is designed to form a precipitate of insulin following injection, creating a slow releasing “basal insulin” over a period of 12 to 24 hours. | 11-17-2011 |
20120178675 | Compositions And Methods For Modulating The Pharmacokinetics and Pharmacodynamics of Insulin - Compositions and methods for modulating the pharmacokinetics and pharmacodynamics of rapid acting injectable insulin formulations are described herein. In the preferred embodiment, the formulations are administered via subcutaneous injection. The formulations contain insulin in combination with a zinc chelator such as ethylenediaminetetraacetic acid (“EDTA”) and a dissolution/stabilization agent, and optionally additional excipients. Calcium disodium EDTA is less likely to remove calcium from the body, and typically has less pain on injection in the subcutaneous tissue. Modulating the type and quantity of EDTA can change the insulin absorption profile. Increasing the quantity of citrate can further enhance absorption and chemically stabilize the formulation. In the preferred embodiment, the formulation contains human insulin, calcium disodium EDTA and a dissolution/stabilization agent such as citric acid or sodium citrate. These formulations are rapidly absorbed into the blood stream when administered by subcutaneous injection. | 07-12-2012 |
20120240929 | UNIT DOSE CARTRIDGE AND DRY POWDER INHALER - A dry powder inhaler having improved aerodynamic properties for diluting, dispersing, and metering drug particles for increasing the efficiency of pulmonary drug delivery to a patient is described. The inhaler comprises, in general, a housing having an air intake, an air flow-control/check-valve, a mixing section and a mouthpiece. A cartridge loaded with a single dose of medicament can be installed in the mixing section. | 09-27-2012 |
20140113856 | Magnesium Compositions for Modulating the Pharmacokinetics and Pharmacodynamics of Insulin and Insulin Analogs, and Injection Site Pain - Compositions and methods for modulating injection site pain associated with rapid acting injectable insulin formulations have been developed for subcutaneous injection. The formulations contain insulin in combination with a zinc chelator such as ethylenediaminetetraacetic acid (“EDTA”), a dissolution/stabilization agent such as citric acid, a magnesium salt, and, optionally, additional excipients. New presentations include rapid acting concentrated insulin formulations and a way to enhance the absorption of commercially available rapid acting analog formulations by mixing them with a vial containing dry powder excipients that accelerate their absorption. Devices for mixing excipient and insulin together at the time of administration, while minimizing residence time of the mixture, are also described. | 04-24-2014 |
20140135263 | Rapid Acting Injectable Insulin Compositions - Injectable insulin formulations with improved stability and rapid onset of action are described herein. The formulations may be for subcutaneous, intradermal or intramuscular administration. In the preferred embodiment, the formulations are administered via subcutaneous injection. The formulations contain insulin in combination with a chelator and dissolution agent, and optionally additional excipients. In the preferred embodiment, the formulation contains human insulin, a zinc chelator such as EDTA and a dissolution agent such as citric acid. These formulations are rapidly absorbed into the blood stream when administered by subcutaneous injection. In the preferred embodiment, the insulin is provided as a dry powder in a sterile vial. This is mixed with a diluent containing a pharmaceutically acceptable carrier, such as water, a zinc chelator such as EDTA and a dissolution agent such as citric acid shortly before or at the time of administration. In another embodiment, the insulin is stored as a frozen mixture, ready for use upon thawing. | 05-15-2014 |
20140357554 | Magnesium Compositions for Modulating the Pharmacokinetics and Injection Site Pain of Insulin - Compositions and methods for modulating injection site pain associated with rapid acting injectable insulin formulations have been developed for subcutaneous injection. The formulations contain insulin in combination with a zinc chelator such as ethylenediaminetetraacetic acid (“EDTA”), a dissolution/stabilization agent such as citric acid, a magnesium salt, and, optionally, additional excipients. New presentations include rapid acting concentrated insulin formulations and a way to enhance the absorption of commercially available rapid acting analog formulations by mixing them with a vial containing dry powder excipients that accelerate their absorption. Devices for mixing excipient and insulin together at the time of administration, while minimizing residence time of the mixture, are also described. | 12-04-2014 |
20150122258 | UNIT DOSE CARTRIDGE AND DRY POWDER INHALER - A dry powder inhaler having improved aerodynamic properties for diluting, dispersing, and metering drug particles for increasing the efficiency of pulmonary drug delivery to a patient is described. The inhaler comprises, in general, a housing having an air intake, an airflow-control/check-valve, a mixing section and a mouthpiece. A cartridge loaded with a single dose of medicament can be installed in the mixing section. | 05-07-2015 |
20150273022 | STABILIZED ULTRA-RAPID-ACTING INSULIN FORMULATIONS - Compositions and methods for enhancing the stability of rapid acting injectable insulin formulations have been developed for subcutaneous injection. The formulations contain insulin in combination with a zinc chelator such as ethylenediaminetetraacetic acid (“EDTA”), a dissolution/stabilization agent such as citric acid, a magnesium salt, a zinc compound and, optionally, additional excipients. New presentations include rapid acting concentrated insulin formulations and a way to enhance the absorption of commercially available rapid acting analog formulations while maintaining insulin stability. | 10-01-2015 |
Russell A. Pohl, Sioux Falls, SD US
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20100233775 | System for the production of methane and other useful products and method of use - A system for the production of methane and other useful products and method of use for generating green natural gas as a fuel or component for use in the manufacturing of specialty chemicals. The system for the production of methane and other useful products and method of use includes a culture of methanogenic archea for converting an input material into an output material, a reactor vessel for housing at least a portion of the culture of methanogenic archea, an input material stream directed into the reactor vessel to facilitate contact between the input material stream and the methanogenic archea, and an output material stream created at least in part by the culture of methanogenic archea. | 09-16-2010 |
20100248344 | Methanogenic reactor - A methanogenic reactor for the production of methane, cellular biomass and other useful products for use in the manufacturing of specialty chemicals. The methanogenic reactor includes a bottom wall, perimeter wall, and top wall defining an interior space environmentally separable from an exterior space outside of the reactor vessel for holding a methanogenic culture and growth media. The reactor also includes at least one sparger positioned substantially within the interior space for facilitating the direction of an input gas stream into the reactor to be brought into contact with the methanogenic culture. The reactor also includes an output material stream port for releasing an output material stream created at least in part by the methanogenic culture. | 09-30-2010 |
Ryan Pohl, Hamden, CT US
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20130123034 | APPARATUS, METHOD, SYSTEM AND COMPUTER PROGRAM PRODUCT FOR RECORDING AND REVIEWING DIGITAL VIDEO MEDIA OF A GOLF SWING - A golf swing training apparatus, system, method and computer program product is disclosed for recording and providing digital review a media recording of a filmed golf swing. The golf swing training apparatus allows a golfer to pay to have his/her swing digitally recorded simultaneously from a plurality of camera perspectives, and to review video media of the golf swing in slow motion so as to improve technique, posture, and swing trajectory. The golf swing training apparatus, in one embodiment, comprises a plurality of cameras, an interface for prompting a golfer to make payment, and a display for reviewing footage of a golf swing from one of a plurality of perspectives. In some embodiments, flashing lights inform the golfer that the recording is about to begin. | 05-16-2013 |
Stephen L. Pohl, Prescott, WI US
Patent application number | Description | Published |
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20140031654 | SENSOR MODULE WITH ENHANCED CAPILLARY FLOW - A sensor module is disclosed herein. The sensor module includes a main housing defining an analysis zone within the housing. The sensor module also includes a skin piercing member mounted within the main housing. The skin piercing member is movable relative to the main housing between a retracted position and an extended position. The main housing of the sensor module defines a fluid sample flow passage that extends from a sampling end of the main housing to the analysis zone. The fluid sample flow passage includes a funnel structure through which the skin piecing member extends when in the extended position. The fluid sample flow passage also includes capillary flow enhancing slots that extend outwardly from opposite sides of the funnel structure. | 01-30-2014 |
William Pohl, Morgan Hill, CA US
Patent application number | Description | Published |
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20080263545 | SIGNAL DELIVERY TO A PROCESS IN A PROCESS GROUP - A method of handling a signal for delivery to a process in a process group along with an apparatus and computer-readable medium storing instructions therefore are described. The method comprises obtaining a lock on a portion of a process group management structure and storing a signal to the process group management structure, wherein the signal is to be delivered to one or more processes of a process group, wherein an operating system manages the process group management structure. The method further comprises transmitting a wakeup signal to a signal daemon and releasing the obtained lock. A method of delivering a signal to a process in a process group is also described. The method comprises obtaining a signal from a process group management structure, obtaining a lock on a process list, transmitting the signal to a process specified in the process list; and releasing the lock on the process list. | 10-23-2008 |
20080270687 | Cache chunked list concrete data type - An embodiment of the invention provides a concrete data type and a method for providing a cached chunked list concrete data type. The method can perform steps including: storing at least one datum in a chunk in a cache line; and setting a lower bit value (LB) in a link/space pointer in the chunk to indicate the empty slots in the chunk. | 10-30-2008 |
20080270728 | BURST STRUCTURE ALLOCATION FOR PARALLEL CACHE PRE-LOADING - A method of allocating memory and a memory allocation apparatus are described. The method comprises allocating a set of memory locations for at least a portion of a data structure, wherein the allocated set comprises memory space storing a counter corresponding to each memory location in the set. A method of traversing a data structure is described. The method comprises incrementing, by a predetermined value, a reference address of a pointer to a first data structure of a portion of a set of allocated memory locations to obtain a reference address to a second data structure in the portion of the set. The portion of the set of allocated memory locations comprises a counter for each allocated memory location. | 10-30-2008 |