Pochan
Daniel J. Pochan, Landenberg, PA US
Patent application number | Description | Published |
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20110165200 | NOVEL HYDROGELS AND USES THEREOF - The present invention provides novel hydrogels and methods of making and using such hydrogels. The present invention provides hydrogels that may be formed by the self-assembly of peptides in solution. Such self-assembly may be brought about by a change in one or more characteristics of the solution. Characteristics of the solution that may be changed include pH, ionic strength, temperature, and concentration of one or more specific ions. In addition, hydrogels of the invention may be disassembled by changing one or more characteristic of the hydrogel such as pH, ionic strength, temperature, and concentration of one or more specific ions. | 07-07-2011 |
Darrin J. Pochan, Landenberg, PA US
Patent application number | Description | Published |
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20090238788 | DELIVERY OF HYDROGELS AS SPRAYS - A method for delivering β-sheet peptide hydrogels to a target surface by shear-thinning and spraying the peptide hydrogel on the surface is provided. The β-sheet peptide hydrogels can be applied over a range of thicknesses and can cover broad surface areas. The β-sheet peptide hydrogels may also include a therapeutic agent. | 09-24-2009 |
20100034881 | MACROMOLECULAR DIFFUSION AND RELEASE FROM SELF-ASSEMBLED BETA-HAIRPIN PEPTIDE HYDROGELS - A hydrogel for delayed release of an anionic macromolecule, wherein the hydrogel comprises the anionic macromolecule, 150 mM NaCl, and a peptide selected from the group consisting of SEQ ID NO:1 through SEQ ID NO:33 in an aqueous medium at a pH of 7.4; wherein the anionic macromolecule has an isoelectric point of at most 6.8; and wherein the hydrogel is capable of retaining at least 25% of the anionic macromolecule after 28-day extraction at 37° C. with a pH=7.4 BTP buffer containing 150 mM NaCl. | 02-11-2010 |
20110052692 | NOVEL HYDROGELS AND USES THEREOF - The present invention provides novel hydrogels and methods of making and using such hydrogels. The present invention provides hydrogels that may be formed by the self-assembly of peptides in solution. Such self-assembly may be brought about by a change in one or more characteristics of the solution. Characteristics of the solution that may be changed include pH, ionic strength, temperature, and concentration of one or more specific ions. In addition, hydrogels of the invention may be disassembled by changing one or more characteristic of the hydrogel such as pH, ionic strength, temperature, and concentration of one or more specific ions. | 03-03-2011 |
Darrin J. Pochan, Landenburg, PA US
Patent application number | Description | Published |
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20110171304 | INJECTABLE BETA-HAIRPIN PEPTIDE HYDROGEL THAT KILLS METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS - A peptide comprising the sequence VKVKVRVKV | 07-14-2011 |