Pletnev
Alexander G. Pletnev, Gaithersburg, MD US
Patent application number | Description | Published |
---|---|---|
20100316670 | CHIMERIC SLE/DENGUE TYPE 4 ANTIGENIC VIRUSES - Embodiments described herein concern attenuated, St. Louis Encephalitis Virus/dengue virus type 4 antigenic chimeric viruses, which can be used to prepare immunogenic compositions, vaccines, and diagnostic reagents. Methods of making and using the foregoing are provided. | 12-16-2010 |
20120076821 | ANTIGENIC CHIMERIC TICK-BORNE ENCEPHALITIS VIRUS/DENGUE VIRUS TYPE 4 RECOMBINANT VIRUSES - Disclosed herein are chimeric TBEV/DEN4 flaviviruses including a first nucleic acid molecule including a 5′ non-coding region (NCR) from a DEN4 virus, a nucleic acid encoding a C protein and non-structural proteins from a DEN4 virus, and a 3′ NCR from a DEN4 virus, wherein nonstructural protein NS4B includes a phenylalanine at amino acid position 112, nonstructural protein NS5 includes an alanine at amino acid position 654 and an alanine at amino acid position 655, and the 3′ NCR includes a deletion of nucleotides 10478-10507. The chimeric construct also includes a second nucleic acid molecule, which is operably linked to the first nucleic acid molecule, encoding a prM protein and an E protein from a TBEV, wherein the E protein includes an amino acid substitution that differs from the wild type TBEV at amino acid position 315 and a tryptophan at amino acid position 240. Also disclosed are methods of eliciting an immune response using the disclosed TBEV/DEN4 chimeric flaviviruses and immunogenic compositions including the disclosed chimeric flaviviruses and a pharmaceutically acceptable carrier. | 03-29-2012 |
20140004147 | ANTIGENIC CHIMERIC TICK-BORNE ENCEPHALITIS VIRUS/DENGUE VIRUS TYPE 4 RECOMBINANT VIRUSES | 01-02-2014 |
20140294892 | CONSTRUCTION OF WEST NILE VIRUS AND DENGUE VIRUS CHIMERAS FOR USE IN A LIVE VIRUS VACCINE TO PREVENT DISEASE CAUSED BY WEST NILE VIRUS - The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines. | 10-02-2014 |
Alexandre A. Pletnev, Etna, NH US
Patent application number | Description | Published |
---|---|---|
20090259065 | METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS AND HYDROCYANATION - The invention is directed to methods of making organic compounds by metathesis and hydrocyanation. The method of the invention may be used, for example, to make industrial important organic compounds such as diacids, diesters, acid-amines, acid-alcohols, acid-nitriles, ester-amines, ester-alcohols, and ester-nitriles. | 10-15-2009 |
20150094481 | METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS AND HYDROCYANATION - The invention is directed to methods of making organic compounds by metathesis and hydrocyanation. Hydrocyanation functions to introduce a nitrile group into the organic compound. The nitrile group may be converted into an amine group, an aldehyde group, an alcohol group, or a carboxylic acid group. The method of the invention may be used, for example, to make industrial important organic compounds such as diacids, diesters, acid-amines, acid-alcohols, acid-nitriles, ester-amines, ester-alcohols, and ester-nitriles. | 04-02-2015 |
Andrei Pletnev, Minsk BY
Patent application number | Description | Published |
---|---|---|
20150343232 | METHOD OF COMBINED TREATMENT OF MALIGANT TUMORS - The invention relates to oncology. | 12-03-2015 |
Andrei Pletnev US
Patent application number | Description | Published |
---|---|---|
20150343232 | METHOD OF COMBINED TREATMENT OF MALIGANT TUMORS - The invention relates to oncology. | 12-03-2015 |
Andrey S. Pletnev, Minsk BY
Patent application number | Description | Published |
---|---|---|
20120296150 | PORTABLE APPARATUS FOR LOCAL COMBINED ELECTROMAGNETIC IRRIDATION - The present invention relates to the electromagnetic field physiotherapy and may be used for treating and preventing various diseases and disorders. | 11-22-2012 |
Sergey Pletnev US
Patent application number | Description | Published |
---|---|---|
20150343232 | METHOD OF COMBINED TREATMENT OF MALIGANT TUMORS - The invention relates to oncology. | 12-03-2015 |
Sergey Pletnev, Minsk BY
Patent application number | Description | Published |
---|---|---|
20150343232 | METHOD OF COMBINED TREATMENT OF MALIGANT TUMORS - The invention relates to oncology. | 12-03-2015 |
Sergey V. Pletnev, Minsk BY
Patent application number | Description | Published |
---|---|---|
20120296150 | PORTABLE APPARATUS FOR LOCAL COMBINED ELECTROMAGNETIC IRRIDATION - The present invention relates to the electromagnetic field physiotherapy and may be used for treating and preventing various diseases and disorders. | 11-22-2012 |
Sergey Vladimirovich Pletnev, Minsk BY
Patent application number | Description | Published |
---|---|---|
20100179371 | METHOD FOR HYDROMAGNETOTHERAPY (VARIANTS) AND DEVICE FOR REALIZING THE METHOD - This invention relates to the field of medicine, in particular, to the method and device for magnetotherapy and/or prophylaxis of human diseases. The therapeutic effect is achieved by simultaneously combining acoustic and vibration action in the presence of a fluid medium. The effect-producing harmonic exposure is used as an acoustic exposure. Medical solutions are used as a fluid medium. The magnetic field amplitude is modulated by an acoustic signal. | 07-15-2010 |
20120203055 | APPARATUS FOR TREATING AND/OR PREVENTING DISEASES AND FUNCTIONAL DISORDERS OF EXTERNAL GENITAL ORGANS - The present invention relates to a method for treatment and/or prevention of diseases and functional disorders of external genital organs and a device for realizing the same. The method comprises exposure of an organ to periodic action of vacuum and/or mechanical oscillations and low-frequency pulsed magnetic field and is characterized in that the organ is additionally exposed to a light field and the light exposure of different wavelengths is combined. | 08-09-2012 |