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Pinar Akcora, New York, NY US

Patent application numberDescriptionPublished
20100303874ANISOTROPIC SELF-ASSEMBLY OF NANOPARTICLES IN COMPOSITES - An anisotropic self assembled structure comprises isotropic grafted nanoparticles in a polymeric matrix, the self-assembled structure comprising (a) a one-dimensional string of the grafted nanoparticles within the matrix, the string having a width of one nanoparticle and a length of 1-10 nanoparticles, (b) a substantially two-dimensional sheet of the grafted nanoparticles within the matrix, the sheet having a length and a breadth of at least one micron respectively, wherein the sheet is about 2-5 nanoparticles in thickness, or (c) a plurality of three dimensionally interconnected structures where the width of each of the structures is 1-10 nanoparticles; wherein each grafted nanoparticle comprises a substantially spherical inorganic core nanoparticle and a polymeric brush structure grafted thereto.12-02-2010

Pinar Akpinar, Santa Monica, CA US

Patent application numberDescriptionPublished
20100119489Stimulation of Pancreatic Beta Cell Proliferation - This invention provides a polypeptide, TMEM27, and secreted forms thereof, nucleic acids and constructs encoding the same, and cells comprising the same. The TMEM27 protein is expressed in hormone positive cells at early stages of pancreas development and pancreatic β-cells in the mature pancreas, whose expression promotes pancreatic β-cell replication and increased islet mass. Applications of the protein in diagnostics and therapeutics are described.05-13-2010

Pinar Karpinar, Goettingen DE

Patent application numberDescriptionPublished
20110296539Mutant Alpha-Synuclein, and Methods Using Same - The present invention relates to a mutant human alpha-synuclein with increased toxicity compared to wild-type alpha-synuclein, or a homologue thereof, wherein the mutant alpha-synuclein or homologue thereof comprises at least one amino acid substitution selected from the group consisting of a substitution at the alanine at position 56 (A56), at the alanine at position 76 (A76), at the methionine at position 127 (M127) and/or at the valine at position 118 (V118), as defined in the claims. Further, the invention relates to a polynucleotide encoding the mutant alpha-synuclein or homologue thereof, or an expression vector comprising said polynucleotide, a cell comprising the polynucleotide or expression vector, as defined in the claims. Also, a non-human animal comprising the cell of the invention is provided, as defined in the claims. Finally, the invention provides methods for identifying a substance that prevents or reduces toxicity of alpha-synuclein, as defined in the claims.12-01-2011

Pinar Tabur, Emeryville, CA US

Patent application numberDescriptionPublished
20120040396METHODS FOR PURIFYING BIO-ORGANIC COMPOUNDS - Methods and systems for purifying bio-organic compounds are described. In certain embodiments, the methods comprise the steps of (a) providing a composition or an emulsion comprising a surfactant, host cells, an aqueous medium and a bio-organic compound produced by the host cells, wherein the solubility of the surfactant in the aqueous medium decreases with increasing temperature and wherein the temperature of the composition or emulsion is at least about 1° C. below a phase inversion temperature of the composition or emulsion; (b) raising the temperature of the composition or emulsion to at least about 1° C. above the phase inversion temperature; and (c) performing a liquid/liquid separation of the composition to provide a crude bio-organic composition or emulsion.02-16-2012

Pinar Taskiran-Cyr, Doraville, GA US

Patent application numberDescriptionPublished
20090158383System and Method for Upgrading a Multiprocessor Set-Top Box Device with a Monolithilic Firmware Image - A system and method for downloading a code image at a set-top gateway host that includes an embedded set-top box and an embedded cable modem. The embedded set-top box and the embedded cable modem interact so that each leverages the resources of the other, thereby minimizing the functionality that must be built into each.06-18-2009

Pinar Wennerberg, Munich DE

Patent application numberDescriptionPublished
20090313243METHOD AND APPARATUS FOR PROCESSING SEMANTIC DATA RESOURCES - A semantic data resource of a domain is processed by calculating relevance scores for terms which occur in domain corpora and weighting the semantic data resource depending on the relevance scores calculated for these terms. The semantic data resource may include domain-specific terms and relations, such as a domain ontology, a domain terminology and a domain classification. The domain ontology may include a domain-specific-hierarchy of terms assigned to nodes which are connected by edges and may be encoded in a web ontology language. The relevance scores may be chi-square scores which are calculated depending on a frequency of a term in the domain corpora and an expected frequency of the term.12-17-2009
20110016130Method and an apparatus for providing at least one configuration data ontology module - A method and an apparatus provide at least one configuration data ontology module. Modules are extracted from an ontology under consideration of the semantics of the ontology. Therefore, individual concepts are selected from the ontology which are in a subsequent step connected by relations. The method and apparatus are used in ontology modularization, and especially in biomedical application domains.01-20-2011

Pinar Zorlutuna, Ankara TR

Patent application numberDescriptionPublished
20100167401STACKED, PATTERNED BIOMATERIALS AND/OR TISSUE ENGINEERING SCAFFOLDS - Stacked, lamellar constructs comprised of, synthetic or natural, polymeric membrane structures which are brought together to form 3D scaffolds for biomaterial and guided tissue engineering applications have been developed. Each layer can have 2D or 3D nano and micro topographical features similar to or different than each other which can be arranged during the construction of each lamellae and their orientation can be adjusted during construction phase of the 3D structure. Such a construct was utilized in the development of an artificial cornea with human primary cells, in which patterned surface of the components of the lamellar structure mimics the oriented collagen structure inherent in natural cornea. Similar exploitation of the 3D patterned structure can be made for tissues where aligned ECM architecture is crucial, such as ligaments, bone, tendon, skin.07-01-2010