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Pilon, US
Anthony R. Pilon, Lancaster, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080228413 | SYSTEMS AND METHODS FOR PREDICTING ACOUSTIC SIGNATURES - A system for determining an acoustic signature of a device is disclosed that includes a computer processor operable to determine strength and location of shock wave sound signals based on propagation of sound waves generated by the device. The strength and location of the shock wave signals are modified due to dissipation and dispersion effects in a non-uniform atmosphere. The shock wave signals are separated into even and odd numbered signals, and oscillations in the signals are smoothed by averaging even and odd numbered shock signals. | 09-18-2008 |
Aprile L. Pilon, Gaithersburg, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090029917 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF FIBROTIC CONDITIONS & IMPAIRED LUNG FUNCTION & TO ENHANCE LYMPHOCYTE PRODUCTION - The present invention provides methods and compositions to treat fibrotic conditions, to increase lymphocyte production in vivo, and to improve and/or normalize lung function, pulmonary compliance, blood oxygenation, and blood pH to inhibit inflammatory processes to stimulate or inhibit pro-inflammatory and immune cells, and to inhibit migration of vascular endothelial cells. The invention contemplates the administration of human uteroglobin, native or recombinant, as a means of achieving these ends. Specifically, it has been found that uteroglobin inhibits cell adhesion to fibronectin, increases lymphocyte production in vivo, and improves and/or normalizes lung function, pulmonary compliance, blood oxygenation, and blood pH, and inhibits inflammatory process. In addition it has been found that uteroglobin can stimulate or inhibit pro-inflammatory and immune cells and inhibitor migration of vascular endothelial cells. | 01-29-2009 |
| 20100183640 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF FIBROTIC CONDITIONS AND IMPAIRED LUNG FUNCTION AND TO ENHANCE LYMPHOCYTE PRODUCTION - The present invention provides methods and compositions to treat fibrotic conditions, to increase lymphocyte production in vivo, and to improve and/or normalize lung function, pulmonary compliance, blood oxygenation, and blood pH to inhibit inflammatory processes to stimulate or inhibit pro-inflammatory and immune cells, and to inhibit migration of vascular endothelial cells. The invention contemplates the administration of human uteroglobin, native or recombinant, as a means of achieving these ends. Specifically, it has been found that uteroglobin inhibits cell adhesion to fibronectin, increases lymphocyte production in vivo, and improves and/or normalizes lung function, pulmonary compliance, blood oxygenation, and blood pH, and inhibits inflammatory process. In addition it has been found that uteroglobin can stimulate or inhibit pro-inflammatory and immune cells and inhibitor migration of vascular endothelial cells. | 07-22-2010 |
Aprile L. Pilon, Germantown, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20090197808 | METHODS AND COMPOSITIONS FOR THE REDUCTION OF NEUTROPHIL INFLUX AND FOR THE TREATMENT OF BRONCHPULMONARY DYSPLASIA, RESPIRATORY DISTRESS SYNDROME, CHRONIC LUNG DISEASE, PULMONARY FIBROSIS, ASTHMA AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE - The present invention relates generally to the use of recombinant human CC10 (rhCC10), also known as recombinant human uteroglobin, for use as a therapeutic in the treatment of Respiratory Distress Syndrome (RDS), Bronchopulmonary dysplasia (BPD), chronic lung disease and/or pulmonary fibrosis, Asthma and Chronic Obstructive Pulmonary Disease (COPD). More particularly, the invention provides methods, including broadly the critical dosage ranges of rhCC10, which may be administered to safely and effectively treat the aforementioned conditions. The invention further provides a composition useful in administering rhCC10 to humans. | 08-06-2009 |
| 20110240012 | RECOMBINANT HUMAN CC10 AND COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF NASAL RHINITIS - The present invention relates generally to the use of recombinant human CC10 (rhCC10), also known as recombinant human uteroglobin, for use as a therapeutic in the treatment of nasal rhinitis, nasal sinusitis, chronic rhinosinusitis, and nasal polyposis. More particularly, the invention provides methods, including broadly the critical dosage ranges of rhCC10 and intranasal route of administration, which may be administered to safely and effectively treat the aforementioned conditions. The invention further provides a composition useful in administering rhCC10 to humans. | 10-06-2011 |
Brent Pilon, Greenville, TN US
| Patent application number | Description | Published |
|---|---|---|
| 20110278212 | SEDIMENT AND DETENTION BASIN DRAINAGE SYSTEM AND METHOD - A fluid drainage system configured for draining a basin impounding fluid and sediment, solids or the like of varying density and turbidity. The system includes a first conduit and a second conduit within or adjacent to the first conduit to form a fluid receiving chamber between the first and second conduits, each conduit having apertures therethrough, with the apertures of the first and second conduits being sized and arranged relative to one another and so configured as to preferentially discharge fluid from the top of a basin, thus providing flow conditions which inhibit the entry of sediment into the system so as to maximize the retention of sediment within the basin and reduce turbidity and Total Suspended Sediment in the discharged fluid. | 11-17-2011 |
Laurent G. Pilon US
| Patent application number | Description | Published |
|---|---|---|
| 20110298333 | DIRECT CONVERSION OF NANOSCALE THERMAL RADIATION TO ELECTRICAL ENERGY USING PYROELECTRIC MATERIALS - The embodiment provided herein are directed to a pyroelectric (PE) energy converter which is capable of combining nanoscale thermal radiation and pyroelectric energy conversion for harvesting low grade waste heat. The converter advantageously makes use of the enhanced radiative heat transfer across a nanosize gap to achieve high operating frequencies or large temperature oscillations in a composite PE plate. The PE energy converter generally comprises a hot source, a cold source, and a PE plate, wherein the PE plate oscillates between the hot and cold source and the PE plate can be subjected to a power cycle in the displacement-electric field diagram. The hot and cold sources of the converter can be coated with SiO | 12-08-2011 |
Lawrence Pilon, Grand Island, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090056577 | Compositions compatible with jet printing and methods therefor - Apparatus and methods for controlling application of a substance to a substrate involve the use of a gating agent that blocks the substance from or attracts the substance to the substrate. The apparatus and methods may utilize ink jet technology to apply the gating agent directly to the substrate or to an intermediate surface. The gating agent composition includes a nonionic surfactant, and water. The gating agent composition does not contain a discernable amount of dye, pigment or other colorant agent. | 03-05-2009 |
| 20090064886 | Apparatus and methods for controlling application of a substance to a substrate - Apparatus and methods for controlling application of a substance to a substrate involve the use of a functional agent that blocks the substance from or attracts the principal substance to the substrate. The apparatus and methods may utilize ink jet technology to apply the functional agent directly to the substrate or to an intermediate surface. The principal substance may be an ink, a dye, a marking substance other than an ink, or a carrier for any other type of substance. | 03-12-2009 |
Michael Pilon, Littleton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090050786 | Fast and Precise Time-Resolved Spectroscopy with Linear Sensor Array - Time-resolved analysis of a spectrum is performed by illuminating a one-dimensional array of charge-transfer device light-sensitive pixel cells and periodically non-destructively copying charges in the light-sensitive cells to respective storage cells (“row storage registers”) co-located with the light-sensitive cells in an integrated circuit. Information about the charges stored in at least some of the storage cells is provided to a component external to the integrated circuit. | 02-26-2009 |
Roger E. Pilon, Avoca, MI US
| Patent application number | Description | Published |
|---|---|---|
| 20100207001 | Conductive And Isolated 2-Shot Tube Clamp - A clamp includes polymeric body portions connected by a living hinge. A retention section is each created in each body portion. Elastically deflectable material insert members have injection molded features adapted to engage to the retention sections. An electrically conductive material is included with the elastically deflectable material to render the clamp electrically conductive. | 08-19-2010 |
| 20100242231 | BREAK-AWAY BUNDLING DEVICE - A bundling device includes a molding of a polymeric material. A flexible strap includes multiple teeth each including a notch. The strap is frangible at the notch of any one of the teeth. A strap engagement portion connected to the strap includes first and second flexible wings defining a strap receiving aperture therebetween receiving the flexible strap in a first direction. The flexible wings engage successive ones of the teeth to oppose removal of the strap in an opposite second direction. The first and second flexible wings each include a first arm having a first raised portion extending into the strap receiving portion; and a second arm having a second raised portion axially displaced with respect to the first raised portion and oriented out of plane with respect to the first raised portion. | 09-30-2010 |
| 20110278760 | FASTENER CLIP WITH SEAL - A single-piece fastener includes a relatively hard clip and a relatively soft seal. The seal can be overmolded onto the clip. A thermal bond is formed between the seal and the clip to inhibit removal of the seal from the clip. The flexible nature of the umbrella of the clip and the seal can accommodate sealing openings in panels of varying thicknesses. | 11-17-2011 |