| Patent application number | Description | Published |
| 20080300220 | Linkable Lewis X Analogs - Disclosed herein is a class of linkable tetrasaccharide compounds that includes the amino phenyl glycoside of sialyl Lewis X (SLe | 12-04-2008 |
| 20090131636 | TARGETING VECTOR-PHOSPHOLIPID CONJUGATES - Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly useful in therapeutic and diagnostic methods, such as in imaging KDR-containing tissue and in the evaluation and treatment of angiogenic processes associated with neoplastic conditions. The present invention also provides processes for the large scale production of highly pure dimeric and monomeric peptide phospholipid conjugates as well as precursor materials used to form the conjugates. The present invention further provides processes for the large scale production of highly pure peptide phospholipid conjugates which contain very low levels of TFA. | 05-21-2009 |
| 20100003195 | KDR AND VEGF/KDR BINDING PEPTIDES AND THEIR USE IN DIAGNOSIS AND THERAPY - The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a K | 01-07-2010 |
| 20100233090 | TARGETING VECTOR-PHOSPHOLIPID CONJUGATES - Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions. Such ultrasound contrast agents are particularly useful in therapeutic and diagnostic methods, such as in imaging KDR-containing tissue and in the evaluation and treatment of angiogenic processes associated with neoplastic conditions. The present invention also provides processes for the large scale production of highly pure dimeric and monomeric peptide phospholipid conjugates as well as precursor materials used to form the conjugates. The present invention further provides processes for the large scale production of highly pure peptide phospholipid conjugates which contain very low levels of TFA. | 09-16-2010 |
| Patent application number | Description | Published |
| 20090148391 | SYNERGISTIC ACTIVE PREPARATIONS COMPRISING DIPHENYLMETHANE DERIVATIVES AND FURTHER SKIN AND/OR HAIR LIGHTENING AND/OR SENILE KERATOSIS REDUCING COMPOUNDS - The present invention relates to specific synergistic active skin- and/or hair-lightening and/or senile keratosis-reducing (cosmetic or pharmaceutical) preparations comprising a mixture comprising or consisting of
| 06-11-2009 |
| 20090297468 | Mixtures Comprising Anthranilic Acid Amides and Cooling Agents as Cosmetic and Pharmaceutical Compositions for Alleviating Itching - The invention relates to a mixture comprising or consisting of:
| 12-03-2009 |
| 20090306154 | SYNERGISTIC ANTI-MICROBIAL MIXTURES OF TROPOLONE (DERIVATIVES) AND SELECTED COMPOUNDS - The present invention relates to the antimicrobial mixture comprising or consisting of:
| 12-10-2009 |
| 20100196504 | SYNERGISTIC ACTIVE PREPARATIONS COMPRISING 1,2-DECANEDIOL AND FURTHER ANTIMICROBIAL ACTIVE COMPOUNDS - The present invention relates to specific synergistic active antimicrobial compositions for hygiene disinfectant products like antimicrobial liquid or solid soaps, disinfectant cleansing solutions and disinfectant emulsions for the treatment of skin surface, specifically for the treatment of hand surface and/or for the treatment of technical surfaces like e.g. surgery equipment comprising a mixture comprising or consisting of
| 08-05-2010 |
| 20100216892 | Use of synergistically active 1,2-alkanediol mixtures as skin moisture-regulating compositions - Synergistically active mixtures of straight-chain 1,2-alkanediols having 5 to 10 C atoms and their use as skin moisture-regulating compositions are described. Binary and ternary mixtures of 1,2-pentanediol, 1,2-hexanediol and 1,2-octanediol have proved to be particularly active here. Cosmetic or pharmaceutical formulations and ready-to-use cosmetic or pharmaceutical products comprising particularly synergistically active mixtures of the 1,2-alkanediols mentioned and the use of these formulations and products are furthermore described. | 08-26-2010 |
| Patent application number | Description | Published |
| 20090132433 | MATCHED FILTER APPROACH TO PORTFOLIO OPTIMIZATION - Given a fixed amount of capital, how to invest it optimally by distributing it among a set of stocks and securities so as to maximize the return while minimizing the overall risk is addressed here. Given that one has full freedom in selecting the type of stocks, a new strategy is outlined here by maximizing the ratio of the gain to risk—rather than minimizing the risk alone—to determine the fraction of capital that must go to each stock. An optimum gain versus variance plot can be used to determine the type of stocks to be selected in addition to their relative quantity for maximum yield over the duration of interest. By modifying the definition of risk to include a function of the covariance matrix of secondary stocks that are sympathetic to the primary stocks of interest, an alternate investment strategy is also developed here. If short selling of stocks and securities is not allowed in a portfolio, then stock selection becomes important so as to maintain the desired fractions to be positive. In this context, a new iterative method that incrementally increases the diagonal loading of the covariance matrix of the primary returns so as to achieve positive weight factors is also developed. | 05-21-2009 |
| 20090147625 | EFFICIENT METHODS FOR WIDEBAND CIRCULAR AND LINEAR ARRAY PROCESSING - The objective of this patent is to develop new signal processing algorithms for a wide-band circular electronically scanned array (CESA) or a wideband linear electronically scanned array (LESA) for use in surveillance and communications applications, where a sequence of pulses are transmitted and their returns are collected by the array for further processing. Instead of partitioning the entire wideband frequency into various subbands and then processing them separately using narrowband schemes, a frequency focusing method is proposed here to compensate and focus the wideband spatio-temporal data into a single narrow frequency band. This is made possible by operating with a pre-computed frequency focusing matrix that transforms the data from various frequency slots that are spread across the entire wideband region into a common narrowband frequency for the array outputs. Finally the focused narrowband data can be processed using conventional space-time adaptive processing methods to suppress the clutter/noise returns and detect any targets present. | 06-11-2009 |
| 20100106442 | GENERATION OF CONSTANT ENVELOPE OR NEARLY-CONSTANT ENVELOPE SIGNALS SATISFYING A GIVEN FOURIER TRANSFORM MAGNITUDE - One or more embodiments of the present invention relates to an iterative method for generating an almost-constant, nearly constant, or substantially-constant envelope time signal with prescribed Fourier transform magnitude in the frequency domain, and a constant envelope time signal whose Fourier transform magnitude closely matches the prescribed Fourier transform magnitude in the frequency domain. Different starting points for the iterative algorithm give rise to different solutions and their accuracy can be adjusted using a monotonic error criterion presented here. | 04-29-2010 |
| 20100164806 | TARGET AND CLUTTER ADAPTIVE ON-OFF TYPE TRANSMIT PULSING SCHEMES - One or more embodiments of the present invention relates to the design an adaptive transmit non-periodic ON-OFF pulse width modulated (PWM) signal sequence over a radar dwell time that is matched to the target and clutter characteristics so as to maximize the target response adaptively. In this context, in the first step, some optimality criterion such as maximizing the ratio of the target output signal power to the mean clutter power at the receiver input is used to design a pre-transmit waveform. In the second step, a Pulse Width Modulation method is used to convert the pre-transmit waveform so designed to a non-periodic ON-OFF pulse width modulated (PWM) waveform signal without destroying the target and clutter matching characteristics of the pre-transmit signal. This allows maximum response from the target and minimum response from the clutter and the environment when the target and its surroundings are interrogated with the non-periodic ON-OFF pulse width modulated (PWM) signal waveform. | 07-01-2010 |