Patent application number | Description | Published |
20090093483 | Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof - Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures: | 04-09-2009 |
20100048572 | NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF - Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures: | 02-25-2010 |
20100160280 | AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS - Pyridine and pyrimidine compounds: | 06-24-2010 |
20110306587 | UNSATURATED NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS - Unsaturated nitrogen heterocyclic compounds of formula (I): | 12-15-2011 |
20110306590 | ARYL- AND HETEROARYL- NITROGEN-HETEROCYCLIC COMPOUNDS AS PDE10 INHIBITORS - Aryl- and heteroaryl-nitrogen heterocyclic compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like. | 12-15-2011 |
20110306591 | HETEROARYLOXYCARBOCYCLYL COMPOUNDS AS PDE10 INHIBITORS - Heteroaryloxycarbocyclyl compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like. | 12-15-2011 |
20130079325 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS PHOSPHODIESTERASE 10 INHIBITORS - Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like. | 03-28-2013 |
20130225552 | HETEROBICYCLIC COMPOUNDS - Heterobicyclic compounds of Formula (I): | 08-29-2013 |
20130338138 | AZETIDINE AND PIPERIDINE COMPOUNDS USEFUL AS PDE10 INHIBITORS - Azetidine and piperidine compounds of formula (I): | 12-19-2013 |
20140148435 | AZETIDINE AND PIPERIDINE COMPOUNDS USEFUL AS PDE10 INHIBITORS - Azetidine and piperidine compounds of formula (I): | 05-29-2014 |
20140213572 | UNSATURATED NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS - Unsaturated nitrogen heterocyclic compounds of formula (I): | 07-31-2014 |
20150376221 | Carbohydrate Phosphonate Derivatives as Modulators of Glycosylation - Compounds of Formula (I) are useful as modulators of glycosylation. Compounds of Formula (I) have the following structure: (I) and the definitions of the other variables are provided herein. | 12-31-2015 |
20160046618 | Cyclopropyl Fused Thiazin-2-Amine Compounds as Beta-Secretase Inhibitors and Methods of Use - The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: | 02-18-2016 |
20160102075 | UNSATURATED NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS - Unsaturated nitrogen heterocyclic compounds of formula (I): | 04-14-2016 |
Patent application number | Description | Published |
20080260187 | Devices and systems including transducers - A device includes a substrate and a transducer attached to the substrate, wherein the substrate includes a surface to which the transducer is attached and at least one edge member extending along at least a portion of the outside edge of the surface. The surface can be a generally planar surface. The edge member is stiffer than the surface. In several embodiments, the transducer is adapted to vibrate. The transducer can, for example, be selected from the group consisting of a piezoelectric transducer, an electrostrictive transducer and a magnetostrictive transducer. Preferably, the transducer is attached to the surface of the substrate by a metallic bonding agent and, more particularly, by welding. | 10-23-2008 |
20110014417 | ANISOTROPIC THERMAL CONDUCTION ELEMENT AND MANUFACTURING METHOD - An anisotropic thermal conductive element that can conduct heat from a thermal source with high efficiency in the thickness direction which maintaining strength and a method of making the element. To achieve the above, an anisotropic thermal conductive element that can conduct heat from a heat source, a structure with a stack of graphite sheets having a contact surface across the thickness direction of the graphite sheets, and the stack of graphite sheets has the surroundings thereof coated to form a support parts. The coating process covers the structure of stacked graphite with a support part. A cutting process can be performed by cutting along the surface in the stacking direction after the coating process. After the cutting process, a surface treatment process can make a surface treatment to a section. | 01-20-2011 |
Patent application number | Description | Published |
20090056383 | HOLEY OPTICAL FIBER WITH RANDOM PATTERN OF HOLES AND METHOD FOR MAKING SAME - A random array of holes is created in an optical fiber by gas generated during fiber drawing. The gas forms bubbles which are drawn into long, microscopic holes. The gas is created by a gas generating material such as silicon nitride. Silicon nitride oxidizes to produce nitrogen oxides when heated. The gas generating material can alternatively be silicon carbide or other nitrides or carbides. The random holes can provide cladding for optical confinement when located around a fiber core. The random holes can also be present in the fiber core. The fibers can be made of silica. The present random hole fibers are particularly useful as pressure sensors since they experience a large wavelength dependant increase in optical loss when pressure or force is applied. | 03-05-2009 |
20110117338 | OPEN PORE CERAMIC MATRIX COATED WITH METAL OR METAL ALLOYS AND METHODS OF MAKING SAME - Open pore foams are coated with metal or metal alloys by electrolytic or electroless plating. The characteristics of the plating bath are adjusted to decrease the surface tension such that the plate bath composition can pass into the pores of the foam, preferably at least two and most preferably more than five pores in depth from the surface of the foam matrix. This can be accomplished by adding a surfactant, solvent or other constituent to reduce the surface tension of the plate bath. In addition, heat and pressure can be used to drive in the plate bath composition into the passage ways of connected open pores in the foam matrix. The net result is to plate the inside surfaces of the pores in the foam matrix, while maintaining the passageways through the foam. Pretreatment of the pore surfaces can be used to promote adhesion of the metal. Particularly advantageous results are achieved when the foam matrix is a ceramic foam. | 05-19-2011 |
20130223804 | HOLEY OPTICAL FIBER WITH RANDOM PATTERN OF HOLES AND METHOD FOR MAKING SAME - A random array of holes is created in an optical fiber by gas generated during fiber drawing. The gas forms bubbles which are drawn into long, microscopic holes. The gas is created by a gas generating material such as silicon nitride. Silicon nitride oxidizes to produce nitrogen oxides when heated. The gas generating material can alternatively be silicon carbide or other nitrides or carbides. The random holes can provide cladding for optical confinement when located around a fiber core. The random holes can also be present in the fiber core. The fibers can be made of silica. The present random hole fibers are particularly useful as pressure sensors since they experience a large wavelength dependant increase in optical loss when pressure or force is applied. | 08-29-2013 |
20140013808 | HOLEY OPTICAL FIBER WITH RANDOM PATTERN OF HOLES AND METHOD FOR MAKING SAME - A random array of holes is created in an optical fiber by gas generated during fiber drawing. The gas forms bubbles which are drawn into long, microscopic holes. The gas is created by a gas generating material such as silicon nitride. Silicon nitride oxidizes to produce nitrogen oxides when heated. The gas generating material can alternatively be silicon carbide or other nitrides or carbides. The random holes can provide cladding for optical confinement when located around a fiber core. The random holes can also be present in the fiber core. The fibers can be made of silica. The present random hole fibers are particularly useful as pressure sensors since they experience a large wavelength dependant increase in optical loss when pressure or force is applied. | 01-16-2014 |
20140200837 | Analysis of Component Having Engineered Internal Space for Fluid Flow - A characteristic of a component having an engineered internal space can be analyzed by recording acoustic signals produced by fluid flow through the internal space at controlled flow rates, and determining one or more acoustic frequencies and acoustic intensities that are indicative of the characteristic of the component. A state and/or a source of the component can be predicted based on the results of such analysis. | 07-17-2014 |
Patent application number | Description | Published |
20110100580 | ONE-PIECE MANUFACTURING PROCESS - A method of making a turbomachine part, wherein the can include machining a blank into a base having blades extending therefrom, the blades defining a channel therebetween. The method can also include forming a bridge in the channel between the blades, and forming a cover on the tops of the blades and over the channel, such that the base, the blades, and the cover form a single substantially homogenous turbomachine part once the bridge is removed. | 05-05-2011 |
20120234512 | ONE-PIECE MANUFACTURING PROCESS - A method of making a turbomachine part, wherein the method can include machining a blank into a base having blades extending therefrom, the blades defining a channel therebetween. The method can also include forming a bridge constructed from refractory material in the channel between the blades, and forming a cover on the tops of the blades and over the channel, such that the base, the blades, and the cover form a single substantially homogenous turbomachine part once the bridge is removed. | 09-20-2012 |
20140230247 | ONE-PIECE MANUFACTURING PROCESS - A method of making a turbomachine part, wherein the method can include machining a blank into a base having blades extending therefrom, the blades defining a channel therebetween. The method can also include forming a bridge constructed from refractory material in the channel between the blades, and forming a cover on the tops of the blades and over the channel, such that the base, the blades, and the cover form a single substantially homogenous turbomachine part once the bridge is removed. | 08-21-2014 |