Phuoc
Phuoc Tran, Ellicott City, MD US
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20140018606 | COMPOUNDS AND METHODS OF USE IN ABLATIVE RADIOTHERAPY - Provided herein is the compound RK-33, or a salt, solvate, stereoisomer, or derivative thereof, which is shown to be an inhibitor if the DEAD box helicase DDX3, in mammalian cells. RK-33 is also provided herein for use as a radiation dose sensitizer in a subject suffering from a proliferative disease and undergoing radiation therapy. Methods of treatment of proliferative diseases, such as cancer with a combination of RK-33 and radiotherapy methods such as stereotactic ablative radiotherapy (SABR) are also provided. | 01-16-2014 |
20140121130 | METHOD OF DETERMINING THE PROGNOSIS OF HEPATOCELLULAR CARCINOMAS USING A MULTIGENE SIGNATURE ASSOCIATED WITH METASTASIS - Expression of MYC alone, in a conditional transgenic mouse model of Twist1- and MYC-induced hepatocellular carcinoma (HCC), resulted in tumors that failed to metastasize, whereas Twist1 co-expression with MYC resulted in tumors associated with extra-hepatic metastases to the lymph nodes, spleen, peritoneum, and lungs. Twist1 also caused a marked increase in circulating tumor cells. Combined inactivation of Twist1 and MYC resulted in sustained regression of both primary and metastatic tumors as shown by gross and microscopic pathology, X-ray computed tomography and bioluminescence imaging, as well as the suppression of circulating tumor cells. Through genomic analysis a 20-gene signature comprising 17 up-regulated genes and 3 down-regulated genes has been identified that is highly predictive of metastasis and overall survival in human patients with HCC. Another aspect of the disclosure methods of determining the metastatic status of an hepatocellular carcinoma of a patient, comprising obtaining a first differential gene expression profile from a carcinoma sample from a subject having an hepatocellular carcinoma and creating a report summarizing the normalized data obtained by the first gene expression analysis and including a determination of the metastatic status of the hepatic carcinoma. | 05-01-2014 |
Phuoc Tran-Gia, Wurzburg DE
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20090157641 | QUERY ROUTING IN DISTRIBUTED DATABASE SYSTEM - A query message is received at a first server of a plurality of servers of a first server type, at least part of data contained in the query message is transformed to a transforming result, based on the transforming result and a first lookup table at said first server, a storage location of a respective second lookup table at one of said plurality of servers of said first type is determined, the respective second lookup table is accessed at the determined storage location of the respective second lookup table at one of said plurality of servers of said first type, and an indicator indicating a storage location of data requested by the query message is retrieved from the respective second lookup table. | 06-18-2009 |
20090157684 | LOAD DISTRIBUTION IN DISTRIBUTED DATABASE SYSTEM - A state change in a network comprising a master server among a plurality of servers is determined, at the master server, a first lookup table is calculated, said first lookup table indicating respective partitions of a second lookup table distributed among active servers of said plurality of servers, the calculated first lookup table is distributed to each active server, and based on the first lookup table, at the master server, a modified partition of the second lookup table is generated. | 06-18-2009 |
20100074103 | SIMPLE AND RESOURCE-EFFICIENT RESILIENT NETWORK SYSTEMS - The invention is related to a method for resilient multi-path connections between edge devices of a communication network. First are determined connection-specific traffic distribution functions for the multi-paths depending on a plausible failure pattern of active and inactive paths of the multi-path of this connection. Further is selected the traffic distribution function for a multi-path depending on the current failure pattern of active an inactive paths of the multi-path of this connection and is distributed the traffic of the connection onto the path of the corresponding multi-path pursuant to the selected traffic distribution function. An essential advantage of the invention is a significant decrease of network capacity for resilient multi-path connections. Another advantage of the invention is the short reaction time in case of an outage of one or more paths of the multi-path connections. | 03-25-2010 |
Phuoc Tran-Gia, Wuerzburg DE
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20150312305 | METHOD, SYSTEM AND APPARATUS FOR THE TRANSMISSION AND ADAPTION OF DATA - A method for the transmission and adaption of data can include the steps of generating generic requirement documents, identifying a plurality of suitable communication patterns on the basis of the generic requirement documents, determining currently available transport options and their service quality across at least one communication network, and selecting a communication pattern from a plurality of suitable communication patterns based on the network transmission qualities of the at least one communication network. The method can utilize a first functional layer and a second functional layer that are integrated between a software application layer and a network access layer that each receive input documents that are independent of each other. The input documents of the second functional layer can contain transport-related information while the input documents of the first functional layer can contain application-related information. Systems and devices can be configured to facilitate use of embodiments of the method. | 10-29-2015 |
20150312306 | Method and Apparatus for Transmitting Encoded Media Data - A method for transmitting encoded media data on the basis of a layer model includes dividing the media data onto a basic layer and at least one additional enhanced layer, transmitting the basic layer and the at least one enhanced layer via at least two network accesses, selecting a first network access to transmit the basic layer that has a network quality and/or stability that is sufficient for transmitting the basic layer; and selecting at least one second network access from among the network accesses depending upon the bandwidth of the first network access and the quality and stability of the network accesses for transmitting the at least one enhanced layer. An apparatus can be configured to execute the method. In some embodiments, the apparatus can include a communication system, a server computer device and/or a mobile terminal. | 10-29-2015 |