Patent application number | Description | Published |
20110150314 | SPECTRAL ANALYSIS OF BIOLOGICAL GROWTH MEDIA - This disclosure is directed to imaging techniques and image analysis techniques for automated analysis of biological growth media. According to this disclosure, the spectral responses of biological growth media can be used to identify and count biological agents from images of biological growth media. The biological growth media may be illuminated with two or more different wavelengths of electromagnetic radiation, and images of the biological growth media can be captured under these different illuminations. The spectral reflectance values in one or more first images can be normalized based on the spectral reflectance values in one or more second images, wherein the first images are associated with a different wavelength of illumination than the second images. The normalization may allow for better identification of biological agents that manifest on the biological growth media. | 06-23-2011 |
20110151501 | MODULAR SYSTEM AND METHOD FOR DETECTING MICROORGANISMS - A modular automated system ( | 06-23-2011 |
20110158499 | INFORMATION MANAGEMENT IN AUTOMATED PROCESSING OF BIOLOGICAL GROWTH MEDIA - This disclosure is directed to information management techniques that may be used during automated processing of biological growth media. In one embodiment, a method comprises reading one or more identification elements of a biological growth medium, identifying manufacturing information related to the biological growth medium based on the one or more identification elements of the biological growth medium, identifying sample information related to a sample being tested by the biological growth medium based on the one or more identification elements of the biological growth medium, generating one or more images of the biological growth medium, counting biological agents formed on the biological growth medium based on the one or more images, wherein counting the biological agents comprises generating a count value, and associating the manufacturing information, the sample information and the count value with the one or more identification elements of the biological growth medium. | 06-30-2011 |
20120244574 | ILLUMINATION APPARATUS AND METHODS FOR A BIOLOGICAL GROWTH PLATE SCANNER - Illumination apparatus for illuminating growth plates in a biological growth plate ( | 09-27-2012 |
20120252049 | METHODS OF DETECTING MICROORGANISMS AND KITS THEREFORE - A method of detecting microorganisms in a test sample is provided. The method includes the steps of: a) incubating the test sample with a growth media to form an incubated sample, wherein the growth media includes an enzyme substrate and the enzyme substrate includes an enzymatically hydrolysable group and a fluorescent group, wherein microorganisms present in the test sample include an enzyme that hydrolyzes the hydrolysable group from the fluorescent group to form a fluorescently detectable product, wherein the fluorescently detectable product has both an acidic and basic species; b) exciting the fluorescently detectable product with light having a wavelength of Exλiso for a time sufficient for the fluorescently detectable product to emit light, wherein Exλiso is the absorbance isosbestic point of the fluorescently detectable product; and c) detecting light emitted at a wavelength of Emλ1. | 10-04-2012 |
20130149738 | MICROBIAL DETECTION SYSTEM AND METHODS - The disclosure provides culture devices and methods for a microorganism in a sample. The devices include a base member, a cover sheet, an adhesive layer coupled to the base member or the cover sheet, and a cold water-soluble gelling agent disposed on the base member; wherein the devices are substantially optically transmissive when the gelling agent is hydrated with a clear liquid. Methods of use include detecting or enumerating microorganisms. The methods further provide for detecting a microorganism by detecting the presence or size of an abiogenic gas bubble ( | 06-13-2013 |
20130177231 | SPECTRAL ANALYSIS OF BIOLOGICAL GROWTH MEDIA - This disclosure is directed to imaging techniques and image analysis techniques for automated analysis of biological growth media. According to this disclosure, the spectral responses of biological growth media can be used to identify and count biological agents from images of biological growth media. The biological growth media may be illuminated with two or more different wavelengths of electromagnetic radiation, and images of the biological growth media can be captured under these different illuminations. The spectral reflectance values in one or more first images can be normalized based on the spectral reflectance values in one or more second images, wherein the first images are associated with a different wavelength of illumination than the second images. The normalization may allow for better identification of biological agents that manifest on the biological growth media. | 07-11-2013 |
20130316443 | SYSTEM FOR DETECTING MICROORGANISMS - A system for detecting microorganisms in a test sample is provided that includes a fluorescently detectable product having both acidic and basic species, wherein the fluorescently detectable product is the reaction product of (a) an enzyme substrate that comprises an enzymatically hydrolysable group and a fluorescent group and (b) a test sample comprising a microorganism having an enzyme that hydrolyzes the hydrolysable group from the fluorescent group of the enzyme substrate. The fluorescently detectable product has an excitation isosbestic point Exλiso where the absorbance of the acid species is the same as the absorbance of the basic species. The system also includes a first light source having a wavelength of Exλiso for irradiating the fluorescently detectable product, The fluorescently detectable product emits light at a wavelength of Emλ1, and the quantity of light emitted at the wavelength Emλ1 is substantially constant across a pH range of 2.5 to 8.0. | 11-28-2013 |