Peyman
Anusch Peyman, Frankfurt Am Main DE
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20160115246 | METHODS FOR INHIBITING ATHEROSCLEROSIS BY ADMINISTERING AN INHIBITOR OF PCSK9 - The present invention provides methods and compositions for inhibiting atherosclerotic plaque formation in a subject. In certain embodiments, the methods of the present invention comprise selecting a subject who has, or is at risk of developing, atherosclerosis, and administering to the subject a pharmaceutical composition comprising a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody, or antigen binding protein. | 04-28-2016 |
Gholam Peyman, Sun City, AZ US
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20100049447 | Method of modeling the behavior of an eye subjected to an external force - A method for simulating the behavior of an eye comprising the steps of (i) generating a FEM model of the eye representing the physical structure of the eye, the FEM model including an elastic walled corneo-scleral shell, (ii) modeling deformations of the eye with the FEM model, the deformation modeling including the simulated application of at least one external force to the FEM model, and (iv) obtaining FEM model solutions iteratively in an incremental fashion, whereby adjustable nodal pressure is introduced inside the corneo-scleral shell. | 02-25-2010 |
20100100054 | Intravitreal injection device and system - An intravitreal injection system for administering a pharmacological agent formulation to an intravitreal compartment of an eye, comprising (i) an injection member coupled to, or comprising, an internal formulation chamber that is adapted to receive and contain the pharmacological agent formulation therein, (ii) a needle having a first end that is in communication with a formulation chamber and a second injection end, and (iii) a movable platform for positioning the system on the eye, guiding the needle, and limiting the penetration depth of the needle into the eye. | 04-22-2010 |
20110054291 | Eye tonometry apparatus, systems and methods - A system for measuring intraocular pressure (IOP) of an eye, comprising a plurality of force sensors that are adapted to contact a surface of an eye, means for measuring the forces exerted on the force sensors when in contact with the eye surface, and processing means that is adapted to receive the measured forces and determine IOP of the eye as a function of the measured forces. | 03-03-2011 |
20120089021 | Method and system for three-dimensional (3D) imaging of biological structures - An ultrasonic scanning apparatus that includes a unique ultrasonic array to transmit ultrasonic energy to a biological structure, such as an eye. The ultrasonic array provides specific three-dimensional (3-D) information relating to the eye and precise volumetric information relating to structures associated therewith, such as a tumor, prior, during and/or after treatment. The ultrasonic array can also be combined with a therapeutic ultrasonic unit for real-time 3-D observation of a structure and the focal point of the transmitted therapeutic beam(s) on a monitor during the treatment of a structure, e.g., treatment of a lesion. | 04-12-2012 |
20120095349 | Apparatus, systems and methods for laser coagulation of the retina - An integral laser imaging and coagulation apparatus, and associated systems and methods that allow an ophthalmologist to perform laser retinal surgical procedures with an integral laser imaging and coagulation apparatus disposed at a first (i.e. local) location from a control system disposed at a second (i.e. remote) location, e.g., a physician's office. In some embodiments, communication between the integral laser imaging and coagulation apparatus and control system is achieved via the Internet®. | 04-19-2012 |
20120323228 | Laser coagulation of an eye structure from a remote location - An integral laser imaging and coagulation apparatus, and associated systems and methods that allow an ophthalmologist to perform laser retinal surgical procedures with an integral laser imaging and coagulation apparatus disposed at a first (i.e. local) location from a control system disposed at a second (i.e. remote) location, e.g., a physician's office. In some embodiments, communication between the integral laser imaging and coagulation apparatus and control system is achieved via the Internet®. | 12-20-2012 |
20130286309 | Variable Focal Length Achromatic Lens System - A variable focal length achromatic lens includes a flat liquid crystal diffractive lens and a pressure-controlled fluidic refractive lens. The diffractive lens is composed of a flat binary Fresnel zone structure and a thin liquid crystal layer, producing high efficiency and millisecond switching times while applying a low ac voltage input. The focusing power of the diffractive lens is adjusted by electrically modifying the sub-zones and re-establishing phase wrapping points. The refractive lens includes a fluid chamber with a flat glass surface and an opposing elastic polydimethylsiloxane (PDMS) membrane surface. Inserting fluid volume through a pump system into the clear aperture region alters the membrane curvature and adjusts the refractive lens' focal position. Primary chromatic aberration is remarkably reduced through the coupling of the fluidic and diffractive lenses at a number of selected focal lengths. Potential applications include miniature color imaging systems, medical and ophthalmic devices, or any design that utilizes variable focal length achromats. | 10-31-2013 |
Gholam A. Peyman US
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20130079806 | VITREOUS CUTTER - A vitrectomy or needle made of a hard resistance metal glass alloy. The wall of the outer tubing or the entire needle can be illuminated when connected to a light source. The instrument, when inserted inside the tissue or the eye, provides illumination, thereby illuminating the surrounding tissue structure and eliminating the need for additional internal or external illumination. | 03-28-2013 |
Gholam A. Peyman, Tucson, AZ US
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20110039790 | ENHANCED OCULAR NEUROPROTECTION AND NEUROSTIMULATION - Use of topically applied cyclosporine to enhance corneal sensitivity restoration rate in an eye of an individual after ocular surgery such as laser-assisted in situ keratomileusis (LASIK) in which nerves are severed. | 02-17-2011 |
Gholam A. Peyman, New Orleans, LA US
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20090069817 | INTRASTROMAL CORNEAL MODIFICATION - A method for modifying the curvature of a live cornea to correct a patient's vision. The live cornea is first separated into first and second opposed internal surfaces. Next, a laser beam or a mechanical cutting device can be directed onto one of the first and second internal surfaces, or both, if needed or desired. The laser beam or mechanical cutting device can be then used to incrementally and sequentially ablate or remove a three-dimensional portion of the cornea for making the cornea less curved. An ocular material is then introduced to the cornea to modify the curvature. The ocular material can be either a gel or a solid lens or a combination thereof. In one embodiment, a pocket is formed in the central portion of the cornea to receive an ocular material. In another embodiment, a plurality of internal tunnels are formed in the cornea to receive the ocular material. The ocular material can be either a fluid such as a gel or a solid member. In either case, the ocular material is transparent or translucent, and can have a refractive index substantially the same as the intrastromal tissue of the cornea or a different refractive index from the intrastromal tissue of the cornea. | 03-12-2009 |
Kevin Arash Peyman, Richmond, VA US
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20150217848 | AIRSHIP POWERED AEROSPACE VEHICLE - An aerospace vehicle comprising an airplane or spacecraft, operatively coupled to an airship balloon containing lighter than air gas adapted to elevate the vehicle. A control system adapted to deflate the balloon upon reaching a specific altitude by directing the gas to a propulsion system and high pressure gas chambers for powering the vehicle at a greater speed or to a greater altitude. The balloon can be retracted into the vehicle to achieve a better aerodynamic shape and further re-inflated for decreasing the speed of the vehicle upon reaching a destination. | 08-06-2015 |
Nazmi Peyman, Richmond, VA US
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20150157404 | SYSTEM AND METHOD FOR GENERATING HEAT AT TARGET AREA OF PATIENT'S BODY - A method and system is provided for generating and distributing heat at a target area of a patient's body for treating lesions, tumours, cancers, body pain and nerve pain. The generated heat and the tissue temperature are monitored in real time. The system comprises a radio frequency (RF) antenna for receiving the RF waves generated from the RF generator. A RF absorber comprising several closed loop circuits and a miniaturized thermometer are implanted inside the body close to the target tissue. A controller/optimizer regulates a frequency and a transmission timing of the RF waves based on the measured target tissue temperature. The thermometer, the RF absorber and the wireless transmitter are placed in a screw. The RF absorber is made of metal with RF absorption rate higher than that of biological tissues. A ultrasound energy is also used to treat the target area. | 06-11-2015 |
20150217848 | AIRSHIP POWERED AEROSPACE VEHICLE - An aerospace vehicle comprising an airplane or spacecraft, operatively coupled to an airship balloon containing lighter than air gas adapted to elevate the vehicle. A control system adapted to deflate the balloon upon reaching a specific altitude by directing the gas to a propulsion system and high pressure gas chambers for powering the vehicle at a greater speed or to a greater altitude. The balloon can be retracted into the vehicle to achieve a better aerodynamic shape and further re-inflated for decreasing the speed of the vehicle upon reaching a destination. | 08-06-2015 |
Sally Peyman, Leeds GB
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20150099055 | COATED MICROBUBBLES - The present invention relates to methods and apparatus to provide coated microbubbles, particularly but not exclusively microbubbles at least partially coated with a component, for example a clinically active component. Systems of the present invention use electromagnetic fields to move microbubbles between streams of liquids in order to perform coating or washing steps. | 04-09-2015 |
Sally Anne Peyman, Leeds GB
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20140321231 | 3D EXPANDING GEOMETRY - This invention relates to bubble generation, in particular to microbubble generation in a microfluidic device, which bubbles may be useful as contrasting agents or drug delivery vehicles. The invention further relates to apparatuses, systems and methods for manufacturing said microbubbles, microbubbles produced by such methods and to their uses, e.g. in medical, diagnostic and other such applications. The microbubbles are preferentially formed using a microspray regime. | 10-30-2014 |