Inventors list |
Assignees list |
Classification tree browser |
Top 100 Inventors |
Top 100 Assignees |
Pearson, MA
Andre Pearson, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110086822 | Substituted Tetracycline Compounds - The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression. | 04-14-2011 |
Andre Lee Pearson, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100184649 | NOVEL ANTIBACTERIAL AGENTS FOR THE TREATMENT OF GRAM POSITIVE INFECTIONS - The present invention relates to novel lipopeptide compounds, pharmaceutical compositions of these compounds and methods of using these compounds as antibacterial compounds. The compounds of the invention are particularly useful against a variety of bacteria, including resistant strains. The compounds are useful as antibacterial agents against | 07-22-2010 |
Christopher Pearson, Grafton, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120220994 | INVASIVE ABLATION PROBE WITH NON-CORING DISTAL TIP - A medical device for delivering RF energy to a target tissue region includes an elongate delivery cannula having a lumen in communication with a distal opening. A deployment member is positioned and longitudinally movable in the lumen. An array of electrode elements are secured to a distal end of the deployment member, the deployment member being movable from a delivery position, in which the electrode elements are positioned within the lumen, to a deployed position, in which the electrode elements extend distally out of the cannula distal opening. A sealing member formed from a bio-compatible material sufficiently rigid to penetrate solid body tissue partially extends from, and substantially seals, the distal cannula opening when the deployment member is in the delivery position. | 08-30-2012 |
David Pearson, Hudson, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090146331 | DEFORMABLE MOLDS AND METHODS FOR THEIR USE IN THE MANUFACTURE OF OPHTHALMIC LENSES - The present provides deformable molds and methods for manufacturing ophthalmic lenses using deformable molds. The molds of the invention may be used in the custom manufacture of ophthalmic lenses. | 06-11-2009 |
James Philip Pearson, Cambridge, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090118503 | FAAH INHIBITORS - Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole. | 05-07-2009 |
| 20090264653 | USEFUL INDOLE COMPOUNDS - Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO. | 10-22-2009 |
| 20100197708 | INDOLE COMPOUNDS - Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole. | 08-05-2010 |
Jeffrey A. Pearson, Plymouth, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20100261580 | Process And Apparatus For Exercising An Operator - A process is disclosed for enabling an operator to exercise on an exercise device. The process includes measuring a range of movement of the operator during exercising on the exercise device for generating an electronic range of movement data. A strength is measured of the operator during exercising on the exercise device for generating an electronic strength data. An electronic program is designed based on the electronic range of movement data and the electronic strength data. The electronic program is stored in an electronic media. The electronic program is displayed as a moving scale on a screen for instructing the operator to exercise at the same rate as the moving scale to complete the exercise in a timely and controlled matter. | 10-14-2010 |
| 20100292052 | Exercising Apparatus - An apparatus is disclosed for enabling an operator to exercise comprising a frame having a body, a base and a top. A load is positioned on the frame for providing a resistive force. A press is positioned on the frame for displacement by the operator. A linkage joins the load with the press for displacing the load upon displacement of the press by the operator. An arm extends between a support end and a user end. A support pivot secures the support end of the arm to the top of the frame for pivoting the arm about the frame. A user interface inputs and outputs data. A user pivot securing the user interface to the user end of the arm for pivoting the user interface about the arm. | 11-18-2010 |
| 20120302405 | Process and Apparatus for Exercising An Operator - A process is disclosed for enabling an operator to exercise on an exercise device. The process includes measuring a range of movement of the operator during exercising on the exercise device for generating an electronic range of movement data. A strength is measured of the operator during exercising on the exercise device for generating an electronic strength data. An electronic program is designed based on the electronic range of movement data and the electronic strength data. The electronic program is stored in an electronic media. The electronic program is displayed as a moving scale on a screen for instructing the operator to exercise at the same rate as the moving scale to complete the exercise in a timely and controlled matter. | 11-29-2012 |
| 20120316037 | Exercising Apparatus - An apparatus is disclosed for enabling an operator to exercise comprising a frame having a body, a base and a top. A load is positioned on the frame for providing a resistive force. A press is positioned on the frame for displacement by the operator. A linkage joins the load with the press for displacing the load upon displacement of the press by the operator. An arm extends between a support end and a user end. A support pivot secures the support end of the arm to the top of the frame for pivoting the arm about the frame. A user interface inputs and outputs data. A user pivot securing the user interface to the user end of the arm for pivoting the user interface about the arm. | 12-13-2012 |
Jonathan D. Pearson, Topsfield, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20090219980 | Feedback System and Apparatus for Video Compensation - A system and apparatus for compensating cable losses in a video signal transmission system includes feedback circuits to determine the spectral attenuation of a received signal and to control an equalizer circuit to amplify selected frequencies of the received signal, and to determine the various times of arrival of two or more video signals and selectively adjust one or more delay lines to reduce the differences in their arrival times. | 09-03-2009 |
Nathaniel Pearson, Somerville, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120110013 | Flexibly Filterable Visual Overlay Of Individual Genome Sequence Data Onto Biological Relational Networks - The present invention pertains to methods, apparatuses and systems for providing a visually simple and salient display of an individual's genomic data overlaid onto one or more relational networks of one or more biological objects, such as information about genes, regulatory regions, promoters or enhancers. The present invention utilizes individual genomic variant information that is annotated with variant information of one or more relational networks having information of biological objects. The display also provides a representation as to the type and nature of individual's variant associated with the relational network such as homozygous variants, heterozygous variants, previously reported genotype-phenotype association, situation within a splice-site region, category of change (e.g., frameshift, nonsense, missense, etc.), predicted effect on protein function (function-changing, tolerated, etc.), and novelty. | 05-03-2012 |
| 20120191366 | Methods and Apparatus for Assigning a Meaningful Numeric Value to Genomic Variants, and Searching and Assessing Same - The present invention relates to methods, apparatus and computer systems for assigning a numerical value to a genotype at a single- or multi-base segment in an individual's genome to denote the presence of a match or a mismatch of a nucleic acid base sequence of one or more chromosomal copies of the segment, as compared to the nucleic acid base sequence at a reference genome segment that corresponds to the segment of the individual's genome. The methods involve assigning a single digit numerical value to the match or the mismatch of each chromosomal copy of the segment in the genome, so that the numerical value assigned to a mismatch is greater than the numerical value of the match. A null symbol is assigned to a no call determination. The assigned numerical values are summed and a total numerical value which is a single digit or a fixed number of digits is obtained. The steps are repeated to create a vector of total numerical values for the segment among the set of genomes, to thereby obtain a segment-specific pattern of genotype match/mismatch between a set of genomes and the nucleic acid base sequence at the reference genome segment. The segment-specific pattern, also referred to as a “diff pattern” can be used to filter or uncover specific trends or sub-patterns across a set of genomes, and more quickly identify genotypic/phenotypic relationships by identifying sites where the distribution of genotypes in the set of genomes relates in a distinctive, causal way to the distribution of a given phenotype among the individuals whose genomes are under study. | 07-26-2012 |
Tadhg Pearson, Waltham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20120324476 | PASTING DATA - A method of pasting data from a source application to a destination application, where the source and destination applications are not the same; the method comprising the steps of: identifying a data type for the data and an appropriate input handler for the data type; converting the data using the appropriate input handle to a standard format based on the data type; in an output module determining the context of the data in the standard format to identify an appropriate output handler; obtaining a suggested paste operation from a suggestion engine based on the type and context of the data; and instructing a paste operation on the basis of the suggested paste operation. | 12-20-2012 |