| Patent application number | Description | Published |
|---|
| 20080227851 | LAULIMALIDE AND LAULIMALIDE ANALOGS - Novel laulimalide analogs, methods for the treatment of proliferative disease and processes for the synthesis of laulimalide and novel laulimalide analogs are described. | 09-18-2008 |
| 20080280973 | Laulimalide Analogues as Therapeutic Agents - Laulimalide analogues useful as microtubule stabilizing agents, and in the treatment of abnormal cell proliferation, are disclosed. Methods of making the compounds, as well as methods of using such compounds in treating abnormal cell proliferation diseases are also described. | 11-13-2008 |
| 20090099252 | NOVEL LAULIMALIDE ANALOGUES AS THERAPEUTIC AGENTS - Laulimalide analogues useful as microtubule stabilizing agents, and in the treatment of abnormal cell proliferation, are disclosed. Methods of making the compounds, as well as methods of using such compounds in treating abnormal cell proliferation diseases are also described. | 04-16-2009 |
| 20090187046 | Process to Produce Prostratin and Structural or Functional Analogs Thereof - This invention concerns a process to convert a hydroxyl group (bold in R | 07-23-2009 |
| 20090270492 | BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES - Biologically active compounds related to the bryostatin family of compounds, including methods of utilizing the same. | 10-29-2009 |
| 20100081618 | Transporters Comprising Spaced Arginine Moieties - The present invention provides compositions and methods for enhancing transport of biologically active compounds across biological membranes and across and into animal epithelial or endothelial tissues. The composition includes a biologically active agent and a transport moiety. The transport moiety includes a structure selected from the group consisting of (ZYZ) | 04-01-2010 |
| 20100255499 | COMPOSITIONS AND METHODS FOR TRANSPORT OF MOLECULES WITH ENHANCED RELEASE PROPERTIES ACROSS BIOLOGICAL BARRIERS - Conjugates of a cargo molecule with a transporter molecule are disclosed, where the cargo molecule and the transporter molecule are linked covalently by a releasable linker. The cargo of the conjugate can be a biologically active agent or a reporter molecule. The transporter modulates the transport of the cargo across a biological barrier (e.g., a cell membrane) compared to the transport of the unconjugated cargo. Releasable linkers suitable for rapid and facile conjugation to various types of cargo and transporters are also disclosed, along with methods for using the linkers in the synthesis of conjugates. | 10-07-2010 |
| 20100280262 | BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES - Biologically active compounds related to the bryostatin family of compounds, having simplified spacer domains and/or improved recognition domains are disclosed, including methods of preparing and utilizing the same. | 11-04-2010 |
| 20110014699 | PROSTRATIN ANALOGS, BRYOSTATIN ANALOGS, PRODRUGS, SYNTHETIC METHODS, AND METHODS OF USE - Embodiments of the present disclosure provide for prostratin analogs, bryostatin analogs, prodrugs of prostratin and prostratin analogs, methods of making prostratin analogs, and methods of making prodrugs of prostratin and prostratin analogs, methods of use of prostratin analogs, bryostatin analogs, and prodrugs thereof, and the like. | 01-20-2011 |
