Patent application number | Description | Published |
20080200462 | SUBSTITUTED PYRAZOLE AND TRIAZOLE COMPOUNDS AS KSP INHIBITORS - Disclosed are new substituted pyrazole and triazole compounds of Formula (I) and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the derivatives together with pharmaceutically acceptable carriers, and uses thereof: | 08-21-2008 |
20080207589 | CYCLIZED DERIVATIVES AS EG-5 INHIBITORS - The present invention relates to new substituted imidazole compounds have the following Formula (I) and to the pharmaceutically acceptable salts, esters, or prodrugs thereof, to compositions of the compounds together with pharmaceutically acceptable carriers, and to uses of the compounds: | 08-28-2008 |
20090258016 | Substituted imidazole derivatives - The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds. The compounds of the invention have the following general formula: | 10-15-2009 |
20090281100 | Benzimidazole quinolinones and uses thereof - Methods of inhibiting various enzymes and treating various conditions are provided that include administering to a subject a compound of Structure I or IB, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer. Compounds having the Structure I and IB have the following structures and have the variables described herein. Such compounds may be used to prepare medicaments for use in inhibiting various enzymes and for use in treating conditions mediated by such enzymes. | 11-12-2009 |
20090285849 | Thiosemicarbazones as anti-virals and immunopotentiators - Novel immune potentiators, novel vaccine adjuvants, novel compounds and pharmaceutical compositions, as well as novel methods for treating viral infections, including HCV, by administering the compounds and compositions, and novel methods for modulating the immune response by administering the compounds and/or compositions. | 11-19-2009 |
20100034813 | SUBSTITUTED PYRAZOLE AND TRIAZOLE COMPOUNDS AS KSP INHIBITORS - Disclosed are new substituted pyrazole and triazole compounds of Formula (I) and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the derivatives together with pharmaceutically acceptable carriers, and uses thereof: | 02-11-2010 |
20110003791 | Cyclized Derivatives as EG-5 Inhibitors - The present invention relates to new substituted imidazole compounds have the following Formula (I) and to the pharmaceutically acceptable salts, esters, or prodrugs thereof, to compositions of the compounds together with pharmaceutically acceptable carriers, and to uses of the compounds: | 01-06-2011 |
20110028492 | Heteroaryl Compounds and Their Uses - The present invention provides a compound of formula (I): | 02-03-2011 |
20110130380 | Heteroaryl Kinase Inhibitors - The present invention provides compounds of Formula (I): | 06-02-2011 |
20110256128 | TRIAZOLE COMPOUNDS AS KSP INHIBITORS - The present invention provides triazole compounds of Formula I: | 10-20-2011 |
20120165306 | PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES - The present invention provides a compound of Formula (I): | 06-28-2012 |
20120189623 | CYCLIZED DERIVATIVES AS EG-5 INHIBITORS - The present invention relates to new substituted imidazole compounds have the following Formula (I) and to the pharmaceutically acceptable salts, esters, or prodrugs thereof, to compositions of the compounds together with pharmaceutically acceptable carriers, and to uses of the compounds: | 07-26-2012 |
20130017196 | SUBSTITUTED IMIDAZOLE DERIVATIVES - The present invention relates to new substituted imidazole compounds and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the new compounds together with pharmaceutically acceptable carriers, and uses of the new compounds. The compounds of the invention have the following general formula: | 01-17-2013 |
20130172354 | HETEROARYL COMPOUNDS AND THEIR USES - The present invention provides a compound of formula (I): | 07-04-2013 |
20130224186 | OXAZOLE AND THIAZOLE COMPOUNDS AS KSP INHIBITORS - Disclosed are new substituted oxazole and thiazole compounds of Formula (I) and pharmaceutically acceptable salts, esters or prodrugs thereof, compositions of the derivatives together with pharmaceutically acceptable carriers, and uses thereof: | 08-29-2013 |
20130303507 | SUBSTITUTED HETERO-BIARYL COMPOUNDS AND THEIR USES - The present invention provides a compound of formula (II): | 11-14-2013 |
20130324530 | 3-(AMINOARYL)-PYRIDINE COMPOUNDS - The present invention provides a compound of formula (I): | 12-05-2013 |
20140275003 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS - The present invention provides compounds of Formula (I) | 09-18-2014 |
20140288076 | HETEROARYL COMPOUNDS AND THEIR USES - The present invention provides a compound of formula (I): | 09-25-2014 |
20140322247 | CELL PROLIFERATION INHIBITORS AND CONJUGATES THEREOF - Disclosed herein are immunoconjugates comprising an inhibitor of Eg5 linked to an antigen binding moiety such as an antibody, that are useful for treating cell proliferative disorders. Also disclosed are novel inhibitors of Eg5 that can be used either alone or as part of an immunoconjugate to treat cell proliferation disorders. The Eg5 inhibitors include compounds of this formula as described herein: | 10-30-2014 |