Patent application number | Description | Published |
20080269290 | Indoles - The present invention is concerned with novel indol-2-yl-carbonyl-piperidin-benzoimidazolon and indol-2-yl-carbonyl-piperidin-benzoxazolon derivatives as V1 | 10-30-2008 |
20080280898 | Spiro-piperidine derivatives - The present invention is concerned with novel spiro-piperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful in the prevention and/or treatment of anxiety and depressive disorders and other diseases. | 11-13-2008 |
20080281103 | AZASPIRO DERIVATIVES - The present invention is concerned with novel indol-3-yl-carbonyl-azaspiropiperidine derivatives as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use for the treatment of anxiety and depressive disorders and other diseases. In particular, the present invention is concerned with compounds of the general formula (I) | 11-13-2008 |
20100120751 | SPIRO-5,6-DIHYDRO-4H-2,3,5,10B-TETRAAZA-BENZO[E]AZULENES - The present invention is concerned with spiro-dihydrotetraazabenzoazulenes, i.e. spiro-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulenes of formula I | 05-13-2010 |
20100125066 | ALKYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES - The present invention is concerned with alkylcyclohexylethers of dihydro-tetraazabenzoazulenes, i.e. alkylcyclohexylethers of 5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulene s of formula I | 05-20-2010 |
20100222357 | INDOL-3-Y-CARBONYL-PIPERIDIN AND PIPERAZIN-DERIVATIVES - The present invention relates to indol-3-yl-carbonyl-piperidin and piperazin derivatives which act as V1a receptor antagonists and which are represented by Formula I: | 09-02-2010 |
20110105561 | SEROTONIN TRANSPORTER (SERT) INHIBITORS FOR THE TREATMENT OF DEPRESSION AND ANXIETY - The present invention relates to trans-derivatives of formula | 05-05-2011 |
20110105758 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED CYCLIC BETA-ARYL OR HETEROARYLCARBOCYCLIC ACIDS - The present invention relates to a process for the preparation of cis substituted cyclic β-aryl or heteroaryl carboxylic acid derivatives in high diastereo- and enantioselectivity by enantioselective hydrogenation in accordance with the following scheme | 05-05-2011 |
20110245237 | ARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES - The present invention is concerned with aryl-cyclohexyl-tetraazabenzo[e]azulenes of formula I | 10-06-2011 |
20110251183 | ARYL-/HETEROARYL-CYCLOHEXENYL-TETRAAZABENZO[E]AZULENES - The present invention is concerned with aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes of formula I | 10-13-2011 |
20110263573 | HETEROBIARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES - The present invention relates to heterobiaryl-cyclohexyl-tetraazabenzo[e]azulenes of formula I | 10-27-2011 |
20110263578 | HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES - The present invention is concerned with heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes of formula I | 10-27-2011 |
20110275801 | HETEROARYL-CYCLOHEXYL-TETRAAZABENZO[E]AZULENES - The present invention provides heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes of formula I | 11-10-2011 |
20120040990 | INDOL-3-Y-CARBONYL-PIPERIDIN AND PIPERAZIN-DERIVATIVES - The present invention relates to indol-3-yl-carbonyl-piperidin and piperazin derivatives which act as V1a receptor antagonists and which are represented by Formula I: | 02-16-2012 |
20120225865 | ARYLCYCLOHEXYLETHERS OF DIHYDROTETRAAZABENZOAZULENES - The present invention is concerned with arylcyclohexylethers of dihydro-tetraazabenzoazulenes, i.e. arylcyclohexylethers of 5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulenes of formula I | 09-06-2012 |
20130079333 | OXY-CYCLOHEXYL-4H,6H-5-OXA-2,3,10B-TRIAZA-BENZO[E]AZULENES AS V1A ANTAGONISTS - The present invention provides 4H,6H-5-oxa-2,3,10b-triaza-benzo[e]azulenes of the formula | 03-28-2013 |
20130253201 | PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED CYCLIC BETA-ARYL OR HETEROARYL CARBOCYCLIC ACIDS - The present invention relates to a process for the preparation of cis substituted cyclic β-aryl or heteroaryl carboxylic acid derivatives in high diastereo- and enantioselectivity by enantioselective hydrogenation in accordance with the following scheme | 09-26-2013 |
20140221350 | Cyclohexyl-4H,6H-5-oxa-2,3,10b-triaza-benzo[e]azulenes as V1a antagonists - The present invention provides 4H,6H-5-oxa-2,3,10b-triaza-benzo[e]azulenes, which act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful as therapeutics acting peripherally and centrally in the conditions of dysmenorrhea, male or female sexual dysfunction, hypertension, chronic heart failure, inappropriate secretion of vasopressin, liver cirrhosis, nephrotic syndrome, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, and aggressive behavior. | 08-07-2014 |